Perturb_1324_KD_RBM39_SRP301121 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting RBM39 in BE2C neuroblasoma cell line cell line (Study accession: SRP301121) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_1324_KD_RBM39_SRP301121 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
TAS1R3 taste receptor, type 1, member 3 20.0
DQX1 DEAQ box RNA-dependent ATPase 1 20.0
HDAC9 histone deacetylase 9 20.0
MST1 macrophage stimulating 1 20.0
JAM2 junctional adhesion molecule 2 20.0
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 20.0
FN1 fibronectin 1 20.0
GNG13 guanine nucleotide binding protein (G protein), gamma 13 20.0
ARRDC1 arrestin domain containing 1 20.0
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 20.0
NOXO1 NADPH oxidase organizer 1 20.0
COX20 COX20 cytochrome c oxidase assembly factor 20.0
C1ORF111 chromosome 1 open reading frame 111 20.0
JADE1 jade family PHD finger 1 20.0
UBXN6 UBX domain protein 6 20.0
SH3D19 SH3 domain containing 19 20.0
METRN meteorin, glial cell differentiation regulator 20.0
NIT2 nitrilase family, member 2 20.0
MAMDC4 MAM domain containing 4 20.0
CCDC78 coiled-coil domain containing 78 20.0
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 20.0
MPHOSPH8 M-phase phosphoprotein 8 20.0
SIAH1 siah E3 ubiquitin protein ligase 1 20.0
FLRT1 fibronectin leucine rich transmembrane protein 1 20.0
MACROD1 MACRO domain containing 1 20.0
CORO1B coronin, actin binding protein, 1B 19.3979
SLC19A1 solute carrier family 19 (folate transporter), member 1 18.1308
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 17.9101
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 17.9031
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 17.8601
NCAPG non-SMC condensin I complex, subunit G 17.0472
PEX5L peroxisomal biogenesis factor 5-like 16.983
HMHA1 histocompatibility (minor) HA-1 16.7823
RUNDC3A RUN domain containing 3A 16.7807
FGF22 fibroblast growth factor 22 16.7172
MYO15B myosin XVB 16.2992
H1FX H1 histone family, member X 16.2151
USP34 ubiquitin specific peptidase 34 16.136
SNRK SNF related kinase 16.1026
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 15.8962
SUN2 Sad1 and UNC84 domain containing 2 15.5827
NUP88 nucleoporin 88kDa 15.3146
FAM169A family with sequence similarity 169, member A 15.3087
MEIS2 Meis homeobox 2 14.914
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 14.827
RECQL4 RecQ protein-like 4 14.7048
FANCD2OS FANCD2 opposite strand 14.6947
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 14.1458
NNAT neuronatin 14.079
ZSWIM1 zinc finger, SWIM-type containing 1 14.052
POR P450 (cytochrome) oxidoreductase 13.9462
ADRM1 adhesion regulating molecule 1 13.7687
SCO2 SCO2 cytochrome c oxidase assembly protein 13.6552
PEX1 peroxisomal biogenesis factor 1 13.6268
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 13.6133
CALY calcyon neuron-specific vesicular protein 13.449
MFSD12 major facilitator superfamily domain containing 12 13.4053
RNF224 ring finger protein 224 13.4053
DXO decapping exoribonuclease 13.1995
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 13.1995
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 13.1825
CPTP ceramide-1-phosphate transfer protein 12.9377
ZSWIM8 zinc finger, SWIM-type containing 8 12.9219
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 12.665
NR1D1 nuclear receptor subfamily 1, group D, member 1 12.609
MYRF myelin regulatory factor 12.5537
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 12.3843
EML5 echinoderm microtubule associated protein like 5 12.2603
XRRA1 X-ray radiation resistance associated 1 12.2603
RNF31 ring finger protein 31 12.1463
GCHFR GTP cyclohydrolase I feedback regulator 12.1137
ZNF862 zinc finger protein 862 12.0783
PDCD1 programmed cell death 1 12.0512
ZDHHC8 zinc finger, DHHC-type containing 8 11.9191
NARFL nuclear prelamin A recognition factor-like 11.6804
CRACR2B calcium release activated channel regulator 2B 11.6749
FAM173A family with sequence similarity 173, member A 11.6683
GLS2 glutaminase 2 (liver, mitochondrial) 11.573
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 11.5693
TMEM108 transmembrane protein 108 11.445
KCNK12 potassium channel, two pore domain subfamily K, member 12 11.3118
KANK3 KN motif and ankyrin repeat domains 3 11.2595
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 11.0431
DGKQ diacylglycerol kinase, theta 110kDa 10.9973
PIANP PILR alpha associated neural protein 10.905
HDAC5 histone deacetylase 5 10.8945
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 10.8461
FSD2 fibronectin type III and SPRY domain containing 2 10.6995
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 10.6461
DUOX1 dual oxidase 1 10.5015
RNF151 ring finger protein 151 10.3941
CYSRT1 cysteine-rich tail protein 1 10.1787
KPNA1 karyopherin alpha 1 (importin alpha 5) 10.1122
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 9.81321
TUBB6 tubulin, beta 6 class V 9.80444
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 9.77334
SLC4A2 solute carrier family 4 (anion exchanger), member 2 9.73242
NFE2L3 nuclear factor, erythroid 2-like 3 9.72199
ZFHX3 zinc finger homeobox 3 9.71352
BCAS3 breast carcinoma amplified sequence 3 9.65726

decreased expression

Symbol Name Standardized Value
PPP1R12B protein phosphatase 1, regulatory subunit 12B -20.0
STAB1 stabilin 1 -20.0
CPNE8 copine VIII -20.0
CTRL chymotrypsin-like -20.0
CCDC159 coiled-coil domain containing 159 -20.0
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -20.0
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -20.0
SLC22A25 solute carrier family 22, member 25 -20.0
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -20.0
ATXN2 ataxin 2 -20.0
TCP1 t-complex 1 -20.0
UNC45A unc-45 homolog A (C. elegans) -20.0
CIRBP cold inducible RNA binding protein -20.0
PRR29 proline rich 29 -20.0
KCNK15 potassium channel, two pore domain subfamily K, member 15 -20.0
C12ORF65 chromosome 12 open reading frame 65 -20.0
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -20.0
CENPN centromere protein N -20.0
CCDC33 coiled-coil domain containing 33 -20.0
SARDH sarcosine dehydrogenase -20.0
NR2C2AP nuclear receptor 2C2-associated protein -20.0
SNAP47 synaptosomal-associated protein, 47kDa -20.0
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -20.0
MAPK7 mitogen-activated protein kinase 7 -20.0
MCM3AP minichromosome maintenance complex component 3 associated protein -20.0
EMG1 EMG1 N1-specific pseudouridine methyltransferase -20.0
STRA6 stimulated by retinoic acid 6 -20.0
BCAN brevican -20.0
TUBA1C tubulin, alpha 1c -20.0
YIPF2 Yip1 domain family, member 2 -20.0
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -20.0
ISLR immunoglobulin superfamily containing leucine-rich repeat -20.0
PHKA2 phosphorylase kinase, alpha 2 (liver) -20.0
CGREF1 cell growth regulator with EF-hand domain 1 -20.0
CDK4 cyclin-dependent kinase 4 -20.0
C16ORF70 chromosome 16 open reading frame 70 -20.0
RPL10 ribosomal protein L10 -20.0
C12ORF60 chromosome 12 open reading frame 60 -19.699
STAT1 signal transducer and activator of transcription 1, 91kDa -19.1549
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -18.9586
FKRP fukutin related protein -18.6576
MYLK myosin light chain kinase -18.6198
FKBP15 FK506 binding protein 15, 133kDa -18.4815
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -17.9957
SARM1 sterile alpha and TIR motif containing 1 -17.8539
SNX32 sorting nexin 32 -17.6696
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -17.5272
LRRC55 leucine rich repeat containing 55 -17.3487
PHKG1 phosphorylase kinase, gamma 1 (muscle) -17.1013
CRYBG3 beta-gamma crystallin domain containing 3 -17.0273
LIG3 ligase III, DNA, ATP-dependent -17.007
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -16.965
CDON cell adhesion associated, oncogene regulated -16.9318
KLK2 kallikrein-related peptidase 2 -16.9289
LPCAT3 lysophosphatidylcholine acyltransferase 3 -16.8465
PEX14 peroxisomal biogenesis factor 14 -16.7878
TRAPPC4 trafficking protein particle complex 4 -16.7172
KRT17 keratin 17, type I -16.5629
CEP44 centrosomal protein 44kDa -16.5611
C15ORF40 chromosome 15 open reading frame 40 -16.5102
C1ORF122 chromosome 1 open reading frame 122 -16.3992
RSPH9 radial spoke head 9 homolog (Chlamydomonas) -15.959
APC2 adenomatosis polyposis coli 2 -15.7819
KIF2A kinesin heavy chain member 2A -15.45
SNAP23 synaptosomal-associated protein, 23kDa -15.3121
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) -15.3121
PRR19 proline rich 19 -15.3074
HIST1H4I histone cluster 1, H4i -15.2455
CYB561 cytochrome b561 -15.2244
HOOK2 hook microtubule-tethering protein 2 -14.943
PCNXL4 pecanex-like 4 (Drosophila) -14.9287
BRD7 bromodomain containing 7 -14.1439
ENDOG endonuclease G -13.9993
FAM134C family with sequence similarity 134, member C -13.9772
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -13.7557
VTI1B vesicle transport through interaction with t-SNAREs 1B -13.2849
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III -13.1725
MRPL43 mitochondrial ribosomal protein L43 -13.1698
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -13.0271
PRICKLE3 prickle homolog 3 (Drosophila) -12.8106
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -12.7689
TSPAN18 tetraspanin 18 -12.7415
CDC42SE1 CDC42 small effector 1 -12.673
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit -12.6652
GPS2 G protein pathway suppressor 2 -12.6452
FAM149B1 family with sequence similarity 149, member B1 -12.3858
SPTB spectrin, beta, erythrocytic -12.3574
TNPO1 transportin 1 -12.3358
NQO2 NAD(P)H dehydrogenase, quinone 2 -12.2862
CCNH cyclin H -12.1853
VIL1 villin 1 -12.1544
UBXN11 UBX domain protein 11 -12.1529
TMEM262 transmembrane protein 262 -12.1396
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -12.1156
GRIP2 glutamate receptor interacting protein 2 -12.1096
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -11.8298
RAPSN receptor-associated protein of the synapse -11.7339
MINA MYC induced nuclear antigen -11.5261
ZNF593OS ZNF593 opposite strand -11.4021
SERHL2 serine hydrolase-like 2 -11.3414