| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting YAP1/WWTR1 in N/TERT2G keratinocytes cell (Study accession: SRP221804) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_13604_KD_YAP1/WWTR1_SRP221804 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | 20.0 |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 | 20.0 |
| PAQR3 | progestin and adipoQ receptor family member III | 20.0 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 | 20.0 |
| BBIP1 | BBSome interacting protein 1 | 20.0 |
| SDR39U1 | short chain dehydrogenase/reductase family 39U, member 1 | 20.0 |
| NCOA3 | nuclear receptor coactivator 3 | 20.0 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 20.0 |
| PLTP | phospholipid transfer protein | 20.0 |
| SULF2 | sulfatase 2 | 18.2441 |
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 17.8327 |
| TLDC2 | TBC/LysM-associated domain containing 2 | 17.6946 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | 17.2815 |
| TBPL1 | TBP-like 1 | 15.3579 |
| CENPP | centromere protein P | 15.11 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 15.0819 |
| TRIM59 | tripartite motif containing 59 | 14.9094 |
| CTRL | chymotrypsin-like | 14.5973 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 14.4523 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 | 14.0822 |
| COG1 | component of oligomeric golgi complex 1 | 13.9585 |
| C5ORF45 | chromosome 5 open reading frame 45 | 13.8572 |
| C7ORF49 | chromosome 7 open reading frame 49 | 13.7264 |
| CLCC1 | chloride channel CLIC-like 1 | 13.4282 |
| HEATR1 | HEAT repeat containing 1 | 13.1874 |
| GLMP | glycosylated lysosomal membrane protein | 12.9869 |
| MINA | MYC induced nuclear antigen | 12.9752 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | 12.9565 |
| RNF214 | ring finger protein 214 | 12.9317 |
| KRT15 | keratin 15, type I | 12.8952 |
| USP50 | ubiquitin specific peptidase 50 | 12.1684 |
| HIST1H4I | histone cluster 1, H4i | 12.0214 |
| FAM184B | family with sequence similarity 184, member B | 11.7073 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 11.5192 |
| COG5 | component of oligomeric golgi complex 5 | 11.4102 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 11.2303 |
| NME7 | NME/NM23 family member 7 | 11.1922 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 11.1824 |
| SAMD14 | sterile alpha motif domain containing 14 | 11.0524 |
| MROH8 | maestro heat-like repeat family member 8 | 10.568 |
| ATG7 | autophagy related 7 | 10.4766 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 10.4354 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 10.0252 |
| CBLN3 | cerebellin 3 precursor | 9.85578 |
| ANGPTL6 | angiopoietin-like 6 | 9.36207 |
| STAG3 | stromal antigen 3 | 9.23451 |
| TMEM79 | transmembrane protein 79 | 9.20459 |
| PUS10 | pseudouridylate synthase 10 | 9.08782 |
| LIMD2 | LIM domain containing 2 | 9.01858 |
| C21ORF2 | chromosome 21 open reading frame 2 | 8.57887 |
| ACOT8 | acyl-CoA thioesterase 8 | 8.49382 |
| BCCIP | BRCA2 and CDKN1A interacting protein | 8.3791 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 8.37298 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C | 8.30097 |
| NCAPG | non-SMC condensin I complex, subunit G | 8.23521 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 | 8.21185 |
| MTFR1 | mitochondrial fission regulator 1 | 8.02514 |
| IAH1 | isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) | 8.00449 |
| FMNL3 | formin-like 3 | 7.94275 |
| POLG | polymerase (DNA directed), gamma | 7.91876 |
| COL7A1 | collagen, type VII, alpha 1 | 7.90976 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 7.8284 |
| DONSON | downstream neighbor of SON | 7.71028 |
| PLD4 | phospholipase D family, member 4 | 7.67169 |
| STRADB | STE20-related kinase adaptor beta | 7.56035 |
| KRT10 | keratin 10, type I | 7.52803 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 7.4706 |
| IL18BP | interleukin 18 binding protein | 7.29969 |
| CCDC85C | coiled-coil domain containing 85C | 7.05356 |
| SLC5A10 | solute carrier family 5 (sodium/sugar cotransporter), member 10 | 7.04017 |
| SRPK2 | SRSF protein kinase 2 | 6.9471 |
| C12ORF65 | chromosome 12 open reading frame 65 | 6.77399 |
| NCBP2L | nuclear cap binding protein subunit 2-like | 6.7418 |
| DNAH10 | dynein, axonemal, heavy chain 10 | 6.63333 |
| MEA1 | male-enhanced antigen 1 | 6.58447 |
| HAGHL | hydroxyacylglutathione hydrolase-like | 6.3859 |
| PLLP | plasmolipin | 6.38566 |
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 6.23464 |
| RRP1 | ribosomal RNA processing 1 | 6.13226 |
| ADRM1 | adhesion regulating molecule 1 | 6.00252 |
| RHOC | ras homolog family member C | 5.92566 |
| TP53I13 | tumor protein p53 inducible protein 13 | 5.7691 |
| SETD6 | SET domain containing 6 | 5.67147 |
| PMEL | premelanosome protein | 5.58071 |
| LRRC24 | leucine rich repeat containing 24 | 5.55507 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 5.55427 |
| GLRX2 | glutaredoxin 2 | 5.52254 |
| NT5DC4 | 5'-nucleotidase domain containing 4 | 5.38523 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 5.36693 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 5.18659 |
| TMEM50B | transmembrane protein 50B | 5.1857 |
| MIA3 | melanoma inhibitory activity family, member 3 | 5.16406 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 5.13609 |
| CRMP1 | collapsin response mediator protein 1 | 5.01739 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | 4.98871 |
| PSCA | prostate stem cell antigen | 4.9466 |
| DDHD2 | DDHD domain containing 2 | 4.89405 |
| MED16 | mediator complex subunit 16 | 4.8648 |
| ELMOD3 | ELMO/CED-12 domain containing 3 | 4.85723 |
| MXRA8 | matrix-remodelling associated 8 | 4.85382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINB11 | serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) | -20.0 |
| DNASE1 | deoxyribonuclease I | -20.0 |
| ATG10 | autophagy related 10 | -20.0 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -20.0 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | -20.0 |
| FAM228B | family with sequence similarity 228, member B | -20.0 |
| FZD4 | frizzled class receptor 4 | -20.0 |
| FSIP1 | fibrous sheath interacting protein 1 | -20.0 |
| SH3D19 | SH3 domain containing 19 | -20.0 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | -20.0 |
| TCP1 | t-complex 1 | -20.0 |
| SNX22 | sorting nexin 22 | -20.0 |
| LRRC75A | leucine rich repeat containing 75A | -20.0 |
| C19ORF54 | chromosome 19 open reading frame 54 | -20.0 |
| FKBP15 | FK506 binding protein 15, 133kDa | -20.0 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -20.0 |
| LOC122455342 | testis-specific serine/proline-rich protein | -20.0 |
| FCMR | Fc fragment of IgM receptor | -20.0 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | -20.0 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | -20.0 |
| GPS2 | G protein pathway suppressor 2 | -19.301 |
| ARL10 | ADP-ribosylation factor-like 10 | -19.301 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -18.4318 |
| SZT2 | seizure threshold 2 homolog (mouse) | -17.9666 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -17.8928 |
| C12ORF73 | chromosome 12 open reading frame 73 | -17.0097 |
| KRT8 | keratin 8, type II | -16.67 |
| PAQR5 | progestin and adipoQ receptor family member V | -15.7747 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) | -15.2697 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -15.1705 |
| ACTN4 | actinin, alpha 4 | -15.1567 |
| CALD1 | caldesmon 1 | -14.3848 |
| THBS1 | thrombospondin 1 | -14.1804 |
| ENO3 | enolase 3 (beta, muscle) | -14.1046 |
| ANXA2 | annexin A2 | -13.0863 |
| ACTB | actin, beta | -12.138 |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | -11.6881 |
| ERCC1 | excision repair cross-complementation group 1 | -11.3709 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -11.1153 |
| TPM4 | tropomyosin 4 | -11.0421 |
| MYL5 | myosin, light chain 5, regulatory | -11.0328 |
| RPL7A | ribosomal protein L7a | -10.785 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | -10.768 |
| MXD3 | MAX dimerization protein 3 | -10.6448 |
| AGBL5 | ATP/GTP binding protein-like 5 | -10.4611 |
| TRIM14 | tripartite motif containing 14 | -10.4611 |
| RPS18 | ribosomal protein S18 | -10.4034 |
| ACTN1 | actinin, alpha 1 | -10.3521 |
| TTI2 | TELO2 interacting protein 2 | -10.0333 |
| CSNK1D | casein kinase 1, delta | -10.0168 |
| GPR137 | G protein-coupled receptor 137 | -9.98274 |
| CSDC2 | cold shock domain containing C2, RNA binding | -9.83976 |
| PTCD1 | pentatricopeptide repeat domain 1 | -9.57843 |
| GDF9 | growth differentiation factor 9 | -9.50603 |
| ZNF575 | zinc finger protein 575 | -9.29941 |
| RPL13A | ribosomal protein L13a | -9.20839 |
| OTUD4 | OTU deubiquitinase 4 | -8.91706 |
| RPS3 | ribosomal protein S3 | -8.74853 |
| CNTN1 | contactin 1 | -8.70052 |
| MCMDC2 | minichromosome maintenance domain containing 2 | -8.44877 |
| CCDC84 | coiled-coil domain containing 84 | -8.34478 |
| RPS24 | ribosomal protein S24 | -8.27589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -8.25825 |
| FBN2 | fibrillin 2 | -8.25309 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -8.23109 |
| RPL10 | ribosomal protein L10 | -8.21727 |
| RPL4 | ribosomal protein L4 | -8.20399 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | -8.00257 |
| TSPAN31 | tetraspanin 31 | -7.46106 |
| RPS25 | ribosomal protein S25 | -7.25073 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -7.13232 |
| PCED1B | PC-esterase domain containing 1B | -7.08119 |
| RPL7 | ribosomal protein L7 | -6.97652 |
| E2F5 | E2F transcription factor 5, p130-binding | -6.87565 |
| TPT1 | tumor protein, translationally-controlled 1 | -6.82266 |
| FAM35A | family with sequence similarity 35, member A | -6.62588 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -6.58208 |
| ENO1 | enolase 1, (alpha) | -6.47815 |
| RPL14 | ribosomal protein L14 | -6.47815 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -6.4668 |
| KIF2A | kinesin heavy chain member 2A | -6.43562 |
| VPS9D1 | VPS9 domain containing 1 | -6.42584 |
| RPS3A | ribosomal protein S3A | -6.27266 |
| RPS28 | ribosomal protein S28 | -6.27168 |
| EBNA1BP2 | EBNA1 binding protein 2 | -6.00201 |
| RPS6 | ribosomal protein S6 | -5.9711 |
| ACTG1 | actin gamma 1 | -5.97077 |
| S100A9 | S100 calcium binding protein A9 | -5.96339 |
| RPLP0 | ribosomal protein, large, P0 | -5.92178 |
| TMEM186 | transmembrane protein 186 | -5.90308 |
| HDDC2 | HD domain containing 2 | -5.86246 |
| ZNF593OS | ZNF593 opposite strand | -5.83991 |
| TMSB10 | thymosin beta 10 | -5.83869 |
| ARHGAP5 | Rho GTPase activating protein 5 | -5.78175 |
| NACA | nascent polypeptide-associated complex alpha subunit | -5.6402 |
| DOPEY1 | dopey family member 1 | -5.6173 |
| TATDN1 | TatD DNase domain containing 1 | -5.60021 |
| MARS | methionyl-tRNA synthetase | -5.55136 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -5.51402 |
| CFAP126 | cilia and flagella associated protein 126 | -5.50773 |
