| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting FOXO1 in Namalwa cell line (Study accession: SRP192099) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_13659_KD_FOXO1_SRP192099 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DUSP5 | dual specificity phosphatase 5 | 20.0 |
| CCL22 | chemokine (C-C motif) ligand 22 | 20.0 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 20.0 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 19.699 |
| BCL2A1 | BCL2-related protein A1 | 19.699 |
| ADGRG5 | adhesion G protein-coupled receptor G5 | 17.6576 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 17.1765 |
| NCF1 | neutrophil cytosolic factor 1 | 16.0088 |
| SCRT1 | scratch family zinc finger 1 | 15.5607 |
| CLEC17A | C-type lectin domain family 17, member A | 14.7535 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 14.2357 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 13.2534 |
| CCL3 | chemokine (C-C motif) ligand 3 | 13.2534 |
| TNFRSF13C | tumor necrosis factor receptor superfamily, member 13C | 13.0556 |
| CD82 | CD82 molecule | 12.0004 |
| CCL4 | chemokine (C-C motif) ligand 4 | 11.8102 |
| TMED4 | transmembrane emp24 protein transport domain containing 4 | 11.7183 |
| EGR3 | early growth response 3 | 11.6171 |
| MACC1 | metastasis associated in colon cancer 1 | 11.2633 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 10.9652 |
| IL10RA | interleukin 10 receptor, alpha | 10.882 |
| CPTP | ceramide-1-phosphate transfer protein | 10.882 |
| RNF213 | ring finger protein 213 | 10.8728 |
| ESPNL | espin-like | 10.7884 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 | 10.6487 |
| CCL4L2 | chemokine (C-C motif) ligand 4-like 2 | 10.4315 |
| C10ORF54 | chromosome 10 open reading frame 54 | 10.0411 |
| FCRL5 | Fc receptor-like 5 | 9.74362 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 9.70754 |
| BTG2 | BTG family, member 2 | 9.70754 |
| LY9 | lymphocyte antigen 9 | 9.59492 |
| TLR4 | toll-like receptor 4 | 9.47356 |
| TMEM229B | transmembrane protein 229B | 9.38385 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 9.28403 |
| PDCD1 | programmed cell death 1 | 9.25424 |
| PTAFR | platelet-activating factor receptor | 9.22049 |
| APOL1 | apolipoprotein L, 1 | 9.00339 |
| ZC3H12D | zinc finger CCCH-type containing 12D | 8.94028 |
| ABI3 | ABI family, member 3 | 8.866 |
| CD83 | CD83 molecule | 8.75137 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 8.5907 |
| ITGB7 | integrin, beta 7 | 8.48788 |
| BMF | Bcl2 modifying factor | 8.39771 |
| TRIM22 | tripartite motif containing 22 | 8.33131 |
| SGK223 | homolog of rat pragma of Rnd2 | 8.22881 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 8.1813 |
| POU2F2 | POU class 2 homeobox 2 | 8.0914 |
| TBX21 | T-box 21 | 8.00375 |
| TMEM150A | transmembrane protein 150A | 7.91542 |
| AMPD3 | adenosine monophosphate deaminase 3 | 7.86119 |
| KIAA1217 | KIAA1217 | 7.75449 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 | 7.67304 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 7.66443 |
| CD1C | CD1c molecule | 7.60775 |
| C11ORF48 | 7.51051 | |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 7.50771 |
| RGS16 | regulator of G-protein signaling 16 | 7.41688 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 7.35451 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | 7.31893 |
| DUSP2 | dual specificity phosphatase 2 | 7.31893 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 7.28661 |
| EBI3 | Epstein-Barr virus induced 3 | 7.26634 |
| PNKD | paroxysmal nonkinesigenic dyskinesia | 7.23515 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 7.21129 |
| CYTH4 | cytohesin 4 | 7.07569 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 | 7.04099 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 6.95772 |
| IFI6 | interferon, alpha-inducible protein 6 | 6.92877 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 6.89653 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 6.88846 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 6.82825 |
| CBX6 | chromobox homolog 6 | 6.77422 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 6.74261 |
| TNRC18 | trinucleotide repeat containing 18 | 6.74261 |
| CTTN | cortactin | 6.73933 |
| IFI27 | interferon, alpha-inducible protein 27 | 6.59806 |
| GSN | gelsolin | 6.52211 |
| ANGPTL2 | angiopoietin-like 2 | 6.45591 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 6.45437 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 6.39298 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 | 6.37468 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 6.3566 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | 6.32832 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 6.29722 |
| CTSZ | cathepsin Z | 6.24955 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 6.08546 |
| LY6E | lymphocyte antigen 6 complex, locus E | 6.06421 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 6.05845 |
| TRAF3IP3 | TRAF3 interacting protein 3 | 5.98085 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | 5.97131 |
| TNFRSF18 | tumor necrosis factor receptor superfamily, member 18 | 5.88505 |
| BCL9L | B-cell CLL/lymphoma 9-like | 5.82778 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 5.80377 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 | 5.68456 |
| NFKBID | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta | 5.68456 |
| TRAF4 | TNF receptor-associated factor 4 | 5.54914 |
| GPR137B | G protein-coupled receptor 137B | 5.47265 |
| ZBTB32 | zinc finger and BTB domain containing 32 | 5.47119 |
| SCAMP5 | secretory carrier membrane protein 5 | 5.45024 |
| COL6A3 | collagen, type VI, alpha 3 | 5.42928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RAG2 | recombination activating gene 2 | -20.0 |
| NUPL1 | nucleoporin like 1 | -20.0 |
| LOC124903372 | uncharacterized LOC124903372 | -20.0 |
| NUCB2 | nucleobindin 2 | -20.0 |
| KIAA0226L | KIAA0226-like | -20.0 |
| SOX4 | SRY (sex determining region Y)-box 4 | -20.0 |
| LINC00998 | long intergenic non-protein coding RNA 998 | -20.0 |
| BEST3 | bestrophin 3 | -20.0 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -19.2218 |
| FLT1 | fms-related tyrosine kinase 1 | -17.317 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -16.5088 |
| RANBP9 | RAN binding protein 9 | -15.7511 |
| KLHL5 | kelch-like family member 5 | -15.2442 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -14.2624 |
| ADAM32 | ADAM metallopeptidase domain 32 | -13.2209 |
| MAPK6 | mitogen-activated protein kinase 6 | -12.6826 |
| ORC1 | origin recognition complex, subunit 1 | -12.5219 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | -12.2197 |
| CSMD1 | CUB and Sushi multiple domains 1 | -12.0004 |
| HMGB1 | high mobility group box 1 | -11.7865 |
| IL1B | interleukin 1, beta | -11.3748 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -10.9924 |
| RTKN2 | rhotekin 2 | -10.5998 |
| GMFG | glia maturation factor, gamma | -10.5515 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -10.1094 |
| DFNA5 | deafness, autosomal dominant 5 | -9.66081 |
| RAD17 | RAD17 homolog (S. pombe) | -9.40774 |
| GSG2 | germ cell associated 2 (haspin) | -9.40301 |
| EFCAB2 | EF-hand calcium binding domain 2 | -9.40301 |
| CCND3 | cyclin D3 | -9.40301 |
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | -9.32582 |
| MNS1 | meiosis-specific nuclear structural 1 | -9.27262 |
| E2F8 | E2F transcription factor 8 | -9.25694 |
| WRB | tryptophan rich basic protein | -9.20137 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -9.00203 |
| DPYSL2 | dihydropyrimidinase-like 2 | -8.89291 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -8.89291 |
| KIF15 | kinesin family member 15 | -8.89291 |
| CEP135 | centrosomal protein 135kDa | -8.86113 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -8.86113 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -8.81787 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | -8.37163 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -8.25876 |
| SMYD2 | SET and MYND domain containing 2 | -7.91222 |
| VRK1 | vaccinia related kinase 1 | -7.83673 |
| SERTAD2 | SERTA domain containing 2 | -7.83673 |
| ZNF101 | zinc finger protein 101 | -7.77519 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -7.73548 |
| XBP1 | X-box binding protein 1 | -7.70355 |
| FCMR | Fc fragment of IgM receptor | -7.56376 |
| RAD51 | RAD51 recombinase | -7.56373 |
| HMGB2 | high mobility group box 2 | -7.49205 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -7.49205 |
| PLK4 | polo-like kinase 4 | -7.4783 |
| ASF1B | anti-silencing function 1B histone chaperone | -7.41722 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | -7.39419 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -7.30267 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -7.27979 |
| E2F1 | E2F transcription factor 1 | -7.18875 |
| ARF3 | ADP-ribosylation factor 3 | -7.07636 |
| IRF4 | interferon regulatory factor 4 | -7.07569 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -7.07335 |
| RFC1 | replication factor C (activator 1) 1, 145kDa | -6.92877 |
| ARL5B | ADP-ribosylation factor-like 5B | -6.91062 |
| TCL1B | T-cell leukemia/lymphoma 1B | -6.90769 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -6.87902 |
| RAB3IP | RAB3A interacting protein | -6.782 |
| STAMBPL1 | STAM binding protein-like 1 | -6.73933 |
| RACGAP1 | Rac GTPase activating protein 1 | -6.71276 |
| TCL1A | T-cell leukemia/lymphoma 1A | -6.67168 |
| BOD1 | biorientation of chromosomes in cell division 1 | -6.66233 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -6.56762 |
| MXD3 | MAX dimerization protein 3 | -6.50517 |
| ZNF569 | zinc finger protein 569 | -6.42065 |
| MESDC1 | mesoderm development candidate 1 | -6.3646 |
| ARL4C | ADP-ribosylation factor-like 4C | -6.30121 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -6.25952 |
| TRAM1 | translocation associated membrane protein 1 | -6.25085 |
| RAPSN | receptor-associated protein of the synapse | -6.2059 |
| CCDC150 | coiled-coil domain containing 150 | -6.15391 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -6.14561 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 | -6.1296 |
| SEPHS1 | selenophosphate synthetase 1 | -6.1157 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | -6.10406 |
| RMI2 | RecQ mediated genome instability 2 | -5.96995 |
| TLE4 | transducin-like enhancer of split 4 | -5.96923 |
| DUSP22 | dual specificity phosphatase 22 | -5.91283 |
| CCDC47 | coiled-coil domain containing 47 | -5.91147 |
| HECA | headcase homolog (Drosophila) | -5.91081 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | -5.84868 |
| HPS4 | Hermansky-Pudlak syndrome 4 | -5.84868 |
| CCDC112 | coiled-coil domain containing 112 | -5.80377 |
| RNF220 | ring finger protein 220 | -5.78619 |
| TIFA | TRAF-interacting protein with forkhead-associated domain | -5.69249 |
| ECEL1 | endothelin converting enzyme-like 1 | -5.6792 |
| CDK1 | cyclin-dependent kinase 1 | -5.67753 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -5.6638 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -5.6638 |
| CCNB2 | cyclin B2 | -5.64729 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -5.64285 |
