Perturb_13677_KD_DHX9_SRP018815 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting DHX9 in NB1 cell line (Study accession: SRP018815) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Perturb_13677_KD_DHX9_SRP018815 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
NOTCH3 notch 3 20.0
SPATS2L spermatogenesis associated, serine-rich 2-like 20.0
FNDC5 fibronectin type III domain containing 5 20.0
TEAD2 TEA domain family member 2 20.0
EPHB4 EPH receptor B4 20.0
SOX4 SRY (sex determining region Y)-box 4 20.0
IGFBP5 insulin-like growth factor binding protein 5 20.0
C2ORF16 chromosome 2 open reading frame 16 20.0
FN1 fibronectin 1 20.0
VASH2 vasohibin 2 20.0
FGFRL1 fibroblast growth factor receptor-like 1 20.0
APOLD1 apolipoprotein L domain containing 1 20.0
FZD2 frizzled class receptor 2 20.0
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 20.0
LPPR3 lipid phosphate phosphatase-related protein type 3 20.0
WBSCR17 Williams-Beuren syndrome chromosome region 17 20.0
MRC2 mannose receptor, C type 2 20.0
OLFM2 olfactomedin 2 20.0
ACSF2 acyl-CoA synthetase family member 2 19.699
CBX2 chromobox homolog 2 19.5229
GNG7 guanine nucleotide binding protein (G protein), gamma 7 19.301
COL11A2 collagen, type XI, alpha 2 19.301
LOXL2 lysyl oxidase-like 2 19.0458
SOX11 SRY (sex determining region Y)-box 11 18.7959
KIF1C kinesin family member 1C 18.6021
IGSF9 immunoglobulin superfamily, member 9 17.699
TMEM173 transmembrane protein 173 16.3598
ITGB5 integrin, beta 5 16.0988
PLAC1 placenta-specific 1 16.0957
CXCL12 chemokine (C-X-C motif) ligand 12 15.7852
LRP1 low density lipoprotein receptor-related protein 1 15.7237
EFNA4 ephrin-A4 15.6952
TRIM36 tripartite motif containing 36 15.6278
CADPS Ca++-dependent secretion activator 15.2947
TRIP6 thyroid hormone receptor interactor 6 14.9761
YPEL1 yippee-like 1 (Drosophila) 14.8668
NTSR1 neurotensin receptor 1 (high affinity) 14.8351
CDON cell adhesion associated, oncogene regulated 14.83
MEIS3 Meis homeobox 3 14.2157
CERS4 ceramide synthase 4 14.1471
YAP1 Yes-associated protein 1 13.6812
TMSB10 thymosin beta 10 13.1756
LRRN2 leucine rich repeat neuronal 2 12.6244
ISLR immunoglobulin superfamily containing leucine-rich repeat 12.5838
MMP2 matrix metallopeptidase 2 12.093
ZCCHC24 zinc finger, CCHC domain containing 24 11.8154
DLX5 distal-less homeobox 5 11.807
ANKFY1 ankyrin repeat and FYVE domain containing 1 11.8019
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 11.7697
TGIF2 TGFB-induced factor homeobox 2 11.7697
HIP1 huntingtin interacting protein 1 11.6471
THSD1 thrombospondin, type I, domain containing 1 11.1918
FBN2 fibrillin 2 11.1649
TMEM2 transmembrane protein 2 10.9493
GRIK3 glutamate receptor, ionotropic, kainate 3 10.8986
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 10.8566
SH3PXD2B SH3 and PX domains 2B 10.7579
DLL1 delta-like 1 (Drosophila) 10.735
DEFA6 defensin, alpha 6, Paneth cell-specific 10.6802
SLAIN1 SLAIN motif family, member 1 10.621
CXCR4 chemokine (C-X-C motif) receptor 4 10.5396
FBLN1 fibulin 1 10.4963
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 10.3985
ZNF251 zinc finger protein 251 10.3732
VANGL2 VANGL planar cell polarity protein 2 10.3549
PSD2 pleckstrin and Sec7 domain containing 2 10.2724
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 10.2535
DENND2A DENN/MADD domain containing 2A 10.2258
GRIP2 glutamate receptor interacting protein 2 10.2069
TP53 tumor protein p53 10.1854
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 10.1552
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 10.0786
ANO6 anoctamin 6 9.72856
DDAH2 dimethylarginine dimethylaminohydrolase 2 9.19099
RBM3 RNA binding motif (RNP1, RRM) protein 3 8.85268
CCDC109B coiled-coil domain containing 109B 8.8152
DCAKD dephospho-CoA kinase domain containing 8.66002
COL4A1 collagen, type IV, alpha 1 8.62584
IQGAP2 IQ motif containing GTPase activating protein 2 8.61176
TP53I11 tumor protein p53 inducible protein 11 8.49093
IGFBPL1 insulin-like growth factor binding protein-like 1 8.47231
PLXDC1 plexin domain containing 1 8.44996
RND3 Rho family GTPase 3 8.39223
DLL3 delta-like 3 (Drosophila) 8.30591
SYNGR4 synaptogyrin 4 8.288
LOXL1 lysyl oxidase-like 1 8.22557
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 8.22557
C1R complement component 1, r subcomponent 8.22076
DPYSL4 dihydropyrimidinase-like 4 8.14931
TSHZ2 teashirt zinc finger homeobox 2 8.12203
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 8.0909
COMT catechol-O-methyltransferase 8.07444
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 8.0539
ADGRA2 adhesion G protein-coupled receptor A2 8.03242
R3HDM2 R3H domain containing 2 7.93676
MED22 mediator complex subunit 22 7.90366
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 7.87291
CAPN1 calpain 1, (mu/I) large subunit 7.82084
CCDC71L coiled-coil domain containing 71-like 7.81461
STK38 serine/threonine kinase 38 7.71577

decreased expression

Symbol Name Standardized Value
PIRT phosphoinositide-interacting regulator of transient receptor potential channels -20.0
GDF15 growth differentiation factor 15 -20.0
HSPB8 heat shock 22kDa protein 8 -20.0
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -20.0
PI15 peptidase inhibitor 15 -20.0
TSPAN7 tetraspanin 7 -20.0
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -20.0
NPTX1 neuronal pentraxin I -20.0
RAB3C RAB3C, member RAS oncogene family -20.0
SNAP25 synaptosomal-associated protein, 25kDa -20.0
LAMC1 laminin, gamma 1 (formerly LAMB2) -20.0
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -20.0
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -20.0
EIF1 eukaryotic translation initiation factor 1 -19.699
ADSL adenylosuccinate lyase -19.699
RASD2 RASD family, member 2 -19.699
GAP43 growth associated protein 43 -19.1549
CTSB cathepsin B -19.0969
NPTXR neuronal pentraxin receptor -18.5376
DDAH1 dimethylarginine dimethylaminohydrolase 1 -17.5229
EMILIN1 elastin microfibril interfacer 1 -17.2441
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -16.7124
LINGO1 leucine rich repeat and Ig domain containing 1 -16.7106
KCNT1 potassium channel, sodium activated subfamily T, member 1 -15.2127
BMP7 bone morphogenetic protein 7 -14.9862
KCNK1 potassium channel, two pore domain subfamily K, member 1 -14.9761
DUSP6 dual specificity phosphatase 6 -14.9761
PDLIM4 PDZ and LIM domain 4 -14.9317
PXDN peroxidasin -14.8582
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -14.8316
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -14.7313
SCRG1 stimulator of chondrogenesis 1 -14.1576
PTPRN protein tyrosine phosphatase, receptor type, N -13.9202
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -13.7279
PTPRJ protein tyrosine phosphatase, receptor type, J -13.4528
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -13.2711
NPTN neuroplastin -12.9649
GCH1 GTP cyclohydrolase 1 -12.8326
ACHE acetylcholinesterase (Yt blood group) -12.7551
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -12.7551
FAM134B family with sequence similarity 134, member B -12.5314
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -12.5229
SGPP2 sphingosine-1-phosphate phosphatase 2 -12.1958
PHTF2 putative homeodomain transcription factor 2 -12.1704
NRN1 neuritin 1 -12.1126
TMEM255A transmembrane protein 255A -12.101
CALCB calcitonin-related polypeptide beta -12.0746
HMP19 HMP19 protein -12.0175
TRIM2 tripartite motif containing 2 -11.6638
EMC10 ER membrane protein complex subunit 10 -11.6316
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 -11.6118
TMEM59L transmembrane protein 59-like -11.4632
FAM167A family with sequence similarity 167, member A -11.3451
NUPR1 nuclear protein, transcriptional regulator, 1 -11.2231
LAMA5 laminin, alpha 5 -11.2231
STC2 stanniocalcin 2 -11.2023
SYT4 synaptotagmin IV -10.936
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 -10.9004
CYB561 cytochrome b561 -10.8986
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -10.7579
EPAS1 endothelial PAS domain protein 1 -10.754
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma -10.6802
GOT1 glutamic-oxaloacetic transaminase 1, soluble -10.4075
CPLX2 complexin 2 -10.3672
GTPBP2 GTP binding protein 2 -10.3549
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -10.3175
RYR1 ryanodine receptor 1 (skeletal) -10.3175
BCAN brevican -10.3175
SMAD9 SMAD family member 9 -10.2533
CPE carboxypeptidase E -10.2444
PCDHGC5 protocadherin gamma subfamily C, 5 -10.1318
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -10.0826
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -10.0826
ALCAM activated leukocyte cell adhesion molecule -9.97087
SDC2 syndecan 2 -9.97087
PCSK1 proprotein convertase subtilisin/kexin type 1 -9.86857
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -9.66238
TCEAL7 transcription elongation factor A (SII)-like 7 -9.65018
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -9.61687
MAP7D2 MAP7 domain containing 2 -9.52454
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -9.47296
PARM1 prostate androgen-regulated mucin-like protein 1 -9.4645
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -9.46093
IARS isoleucyl-tRNA synthetase -9.34006
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -9.2166
NQO2 NAD(P)H dehydrogenase, quinone 2 -9.16144
OGDHL oxoglutarate dehydrogenase-like -9.12976
CLSTN3 calsyntenin 3 -9.10697
PAM peptidylglycine alpha-amidating monooxygenase -9.00196
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -8.99998
CEL carboxyl ester lipase -8.93992
TMEM181 transmembrane protein 181 -8.89652
TRIM67 tripartite motif containing 67 -8.81325
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -8.74377
NGFR nerve growth factor receptor -8.74179
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -8.69362
HABP4 hyaluronan binding protein 4 -8.64812
IMPAD1 inositol monophosphatase domain containing 1 -8.59545
TMEM151A transmembrane protein 151A -8.54896
PTPRR protein tyrosine phosphatase, receptor type, R -8.54147