| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting RET in neuroblasotma cell SK-N-AS cell line (Study accession: ERP126468) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_13850_KO_RET_ERP126468 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 20.0 |
| IL6ST | interleukin 6 signal transducer | 20.0 |
| FN1 | fibronectin 1 | 20.0 |
| PTK7 | protein tyrosine kinase 7 (inactive) | 20.0 |
| LUM | lumican | 20.0 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 20.0 |
| TPM1 | tropomyosin 1 (alpha) | 20.0 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 20.0 |
| FBLN2 | fibulin 2 | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 20.0 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 20.0 |
| VCL | vinculin | 20.0 |
| GRN | granulin | 20.0 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 20.0 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 20.0 |
| LOXL2 | lysyl oxidase-like 2 | 20.0 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 20.0 |
| PITX3 | paired-like homeodomain 3 | 20.0 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 20.0 |
| CCDC80 | coiled-coil domain containing 80 | 20.0 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 20.0 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 20.0 |
| ASS1 | argininosuccinate synthase 1 | 20.0 |
| SQSTM1 | sequestosome 1 | 20.0 |
| FAM129B | family with sequence similarity 129, member B | 20.0 |
| MLLT1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | 20.0 |
| COL1A1 | collagen, type I, alpha 1 | 20.0 |
| CD46 | CD46 molecule, complement regulatory protein | 20.0 |
| GAS1 | growth arrest-specific 1 | 20.0 |
| C3 | complement component 3 | 20.0 |
| TXNRD1 | thioredoxin reductase 1 | 20.0 |
| MRC2 | mannose receptor, C type 2 | 20.0 |
| LAMA5 | laminin, alpha 5 | 20.0 |
| COL3A1 | collagen, type III, alpha 1 | 20.0 |
| MYH9 | myosin, heavy chain 9, non-muscle | 20.0 |
| TRIO | trio Rho guanine nucleotide exchange factor | 20.0 |
| ATP13A3 | ATPase type 13A3 | 20.0 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 20.0 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 20.0 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 20.0 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 20.0 |
| ACTG1 | actin gamma 1 | 20.0 |
| PLEC | plectin | 20.0 |
| TGOLN2 | trans-golgi network protein 2 | 20.0 |
| INHBA | inhibin, beta A | 20.0 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 20.0 |
| COL4A2 | collagen, type IV, alpha 2 | 20.0 |
| COL4A1 | collagen, type IV, alpha 1 | 20.0 |
| CAPN2 | calpain 2, (m/II) large subunit | 20.0 |
| ITGA1 | integrin, alpha 1 | 20.0 |
| CTSB | cathepsin B | 20.0 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 20.0 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 20.0 |
| ITGB5 | integrin, beta 5 | 20.0 |
| EXT1 | exostosin glycosyltransferase 1 | 20.0 |
| ITGA11 | integrin, alpha 11 | 20.0 |
| LRP1 | low density lipoprotein receptor-related protein 1 | 20.0 |
| ANTXR1 | anthrax toxin receptor 1 | 20.0 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 20.0 |
| COL6A1 | collagen, type VI, alpha 1 | 20.0 |
| NID1 | nidogen 1 | 20.0 |
| SLC38A2 | solute carrier family 38, member 2 | 20.0 |
| SLC38A1 | solute carrier family 38, member 1 | 20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 20.0 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 20.0 |
| ITGAV | integrin, alpha V | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 20.0 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 20.0 |
| ADAM12 | ADAM metallopeptidase domain 12 | 20.0 |
| CCNA2 | cyclin A2 | 20.0 |
| LAMB1 | laminin, beta 1 | 20.0 |
| ACTN1 | actinin, alpha 1 | 20.0 |
| COL6A2 | collagen, type VI, alpha 2 | 20.0 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 20.0 |
| MPZL1 | myelin protein zero-like 1 | 20.0 |
| SSFA2 | sperm specific antigen 2 | 20.0 |
| PRNP | prion protein | 20.0 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 20.0 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 20.0 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 20.0 |
| MMP2 | matrix metallopeptidase 2 | 20.0 |
| COL5A1 | collagen, type V, alpha 1 | 20.0 |
| LAMP1 | lysosomal-associated membrane protein 1 | 20.0 |
| KIRREL | kin of IRRE like (Drosophila) | 20.0 |
| TTYH3 | tweety family member 3 | 20.0 |
| ECE1 | endothelin converting enzyme 1 | 20.0 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 20.0 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 20.0 |
| TMSB4X | thymosin beta 4, X-linked | 20.0 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 20.0 |
| HEG1 | heart development protein with EGF-like domains 1 | 20.0 |
| FTH1 | ferritin, heavy polypeptide 1 | 20.0 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 20.0 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 20.0 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 20.0 |
| APP | amyloid beta (A4) precursor protein | 20.0 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 20.0 |
| TGM2 | transglutaminase 2 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UPP1 | uridine phosphorylase 1 | -20.0 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | -20.0 |
| UNC13A | unc-13 homolog A (C. elegans) | -20.0 |
| IL17RD | interleukin 17 receptor D | -20.0 |
| FOXR2 | forkhead box R2 | -20.0 |
| TMEM100 | transmembrane protein 100 | -20.0 |
| PDZD4 | PDZ domain containing 4 | -20.0 |
| IFI44L | interferon-induced protein 44-like | -20.0 |
| PEAR1 | platelet endothelial aggregation receptor 1 | -20.0 |
| TPD52 | tumor protein D52 | -20.0 |
| TERT | telomerase reverse transcriptase | -20.0 |
| SLC16A9 | solute carrier family 16, member 9 | -20.0 |
| EML5 | echinoderm microtubule associated protein like 5 | -20.0 |
| EML1 | echinoderm microtubule associated protein like 1 | -20.0 |
| EFNB2 | ephrin-B2 | -20.0 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) | -20.0 |
| GAP43 | growth associated protein 43 | -20.0 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 | -20.0 |
| B3GNT7 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 | -20.0 |
| ZNF558 | zinc finger protein 558 | -20.0 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -20.0 |
| INA | internexin neuronal intermediate filament protein, alpha | -20.0 |
| VAMP5 | vesicle-associated membrane protein 5 | -20.0 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -20.0 |
| SOX18 | SRY (sex determining region Y)-box 18 | -20.0 |
| C5ORF63 | chromosome 5 open reading frame 63 | -20.0 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | -20.0 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -20.0 |
| C6 | complement component 6 | -20.0 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 | -20.0 |
| UNC80 | unc-80 homolog (C. elegans) | -20.0 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -20.0 |
| RASD1 | RAS, dexamethasone-induced 1 | -20.0 |
| THBS4 | thrombospondin 4 | -20.0 |
| RAB3C | RAB3C, member RAS oncogene family | -20.0 |
| ZNF585B | zinc finger protein 585B | -20.0 |
| NHSL2 | NHS-like 2 | -20.0 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -20.0 |
| ZNF22 | zinc finger protein 22 | -20.0 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -20.0 |
| CABP4 | calcium binding protein 4 | -20.0 |
| RASL10B | RAS-like, family 10, member B | -20.0 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -20.0 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -20.0 |
| TMEM145 | transmembrane protein 145 | -20.0 |
| PCLO | piccolo presynaptic cytomatrix protein | -20.0 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -20.0 |
| CLDN4 | claudin 4 | -20.0 |
| TLR7 | toll-like receptor 7 | -20.0 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -20.0 |
| TMEM200B | transmembrane protein 200B | -20.0 |
| TEX15 | testis expressed 15 | -20.0 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -20.0 |
| NDNF | neuron-derived neurotrophic factor | -20.0 |
| IL20RA | interleukin 20 receptor, alpha | -20.0 |
| HOOK1 | hook microtubule-tethering protein 1 | -20.0 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -20.0 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 | -20.0 |
| TNF | tumor necrosis factor | -20.0 |
| TCEA3 | transcription elongation factor A (SII), 3 | -20.0 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -20.0 |
| ZNF334 | zinc finger protein 334 | -20.0 |
| AARD | alanine and arginine rich domain containing protein | -20.0 |
| CHRNA7 | cholinergic receptor, nicotinic, alpha 7 (neuronal) | -20.0 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -20.0 |
| ACSS1 | acyl-CoA synthetase short-chain family member 1 | -20.0 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -20.0 |
| PCDHAC1 | protocadherin alpha subfamily C, 1 | -20.0 |
| BCL2 | B-cell CLL/lymphoma 2 | -20.0 |
| RTN1 | reticulon 1 | -20.0 |
| HSPA4L | heat shock 70kDa protein 4-like | -20.0 |
| PRUNE2 | prune homolog 2 (Drosophila) | -20.0 |
| PLCL1 | phospholipase C-like 1 | -20.0 |
| IGSF9 | immunoglobulin superfamily, member 9 | -20.0 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | -20.0 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | -20.0 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -20.0 |
| ABCD2 | ATP-binding cassette, sub-family D (ALD), member 2 | -20.0 |
| CDC25A | cell division cycle 25A | -20.0 |
| SBK1 | SH3 domain binding kinase 1 | -20.0 |
| KIAA1804 | mixed lineage kinase 4 | -20.0 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -20.0 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -20.0 |
| ISLR2 | immunoglobulin superfamily containing leucine-rich repeat 2 | -20.0 |
| ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif, 17 | -20.0 |
| TRAF1 | TNF receptor-associated factor 1 | -20.0 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -20.0 |
| NPAS3 | neuronal PAS domain protein 3 | -20.0 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -20.0 |
| DIABLO | diablo, IAP-binding mitochondrial protein | -20.0 |
| ELN | elastin | -20.0 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | -20.0 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 | -20.0 |
| RAB39A | RAB39A, member RAS oncogene family | -20.0 |
| FZD3 | frizzled class receptor 3 | -20.0 |
| RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 | -20.0 |
| HMP19 | HMP19 protein | -20.0 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -20.0 |
| DAND5 | DAN domain family member 5, BMP antagonist | -20.0 |
| MAST1 | microtubule associated serine/threonine kinase 1 | -20.0 |
