Perturb_13920_KD_HNRNPK_SRP312616 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting HNRNPK in neuroblastoma cell SH-SY5Y cell line (Study accession: SRP312616) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_13920_KD_HNRNPK_SRP312616 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 20.0
INSM2 insulinoma-associated 2 20.0
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 20.0
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 20.0
FAM83H family with sequence similarity 83, member H 20.0
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 20.0
RENBP renin binding protein 20.0
NFE2L3 nuclear factor, erythroid 2-like 3 20.0
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 20.0
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 20.0
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 20.0
TMEM151B transmembrane protein 151B 20.0
UNC13D unc-13 homolog D (C. elegans) 20.0
FAM65C family with sequence similarity 65, member C 20.0
GPR27 G protein-coupled receptor 27 20.0
CARTPT CART prepropeptide 20.0
PLD5 phospholipase D family, member 5 20.0
DOCK3 dedicator of cytokinesis 3 20.0
NEU4 sialidase 4 20.0
NFAM1 NFAT activating protein with ITAM motif 1 20.0
CHGA chromogranin A 20.0
CHGB chromogranin B 20.0
RCSD1 RCSD domain containing 1 20.0
CCL2 chemokine (C-C motif) ligand 2 20.0
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 20.0
BLACAT1 bladder cancer associated transcript 1 (non-protein coding) 20.0
CGNL1 cingulin-like 1 20.0
NR0B1 nuclear receptor subfamily 0, group B, member 1 20.0
ASIC4 acid sensing (proton gated) ion channel family member 4 20.0
GPSM3 G-protein signaling modulator 3 20.0
VSIG2 V-set and immunoglobulin domain containing 2 20.0
CMKLR1 chemerin chemokine-like receptor 1 20.0
TSPAN8 tetraspanin 8 20.0
UNC5CL unc-5 homolog C (C. elegans)-like 20.0
CLDN15 claudin 15 20.0
NFASC neurofascin 20.0
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 20.0
PLEKHA6 pleckstrin homology domain containing, family A member 6 20.0
RERG RAS-like, estrogen-regulated, growth inhibitor 20.0
CADPS Ca++-dependent secretion activator 20.0
ATG2A autophagy related 2A 20.0
PRLHR prolactin releasing hormone receptor 20.0
BTBD11 BTB (POZ) domain containing 11 20.0
PCOLCE procollagen C-endopeptidase enhancer 20.0
NCAN neurocan 20.0
LTBP1 latent transforming growth factor beta binding protein 1 20.0
IRF6 interferon regulatory factor 6 20.0
FAR2 fatty acyl CoA reductase 2 20.0
TSTA3 tissue specific transplantation antigen P35B 20.0
RAG2 recombination activating gene 2 20.0
PHOX2A paired-like homeobox 2a 20.0
TRIM58 tripartite motif containing 58 20.0
KDM8 lysine (K)-specific demethylase 8 20.0
PKDREJ polycystin (PKD) family receptor for egg jelly 20.0
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 20.0
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 20.0
AQP5 aquaporin 5 20.0
C11ORF95 chromosome 11 open reading frame 95 20.0
HVCN1 hydrogen voltage gated channel 1 20.0
KRT8 keratin 8, type II 20.0
ELN elastin 20.0
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 20.0
SYNPO synaptopodin 20.0
SPRED3 sprouty-related, EVH1 domain containing 3 20.0
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 20.0
GPC3 glypican 3 20.0
DCN decorin 20.0
DCX doublecortin 20.0
PLCD4 phospholipase C, delta 4 20.0
DEXI Dexi homolog (mouse) 20.0
ATP10D ATPase, class V, type 10D 20.0
GPR68 G protein-coupled receptor 68 20.0
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 20.0
VSTM4 V-set and transmembrane domain containing 4 20.0
FAM174B family with sequence similarity 174, member B 20.0
NAV2 neuron navigator 2 20.0
LHX1 LIM homeobox 1 20.0
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 20.0
NT5E 5'-nucleotidase, ecto (CD73) 20.0
C15ORF59 chromosome 15 open reading frame 59 20.0
C15ORF52 chromosome 15 open reading frame 52 20.0
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 20.0
S100A4 S100 calcium binding protein A4 20.0
ACVRL1 activin A receptor type II-like 1 20.0
CYTL1 cytokine-like 1 20.0
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 20.0
DGKG diacylglycerol kinase, gamma 90kDa 20.0
DGKB diacylglycerol kinase, beta 90kDa 20.0
BTBD19 BTB (POZ) domain containing 19 20.0
LINC00890 long intergenic non-protein coding RNA 890 20.0
TIMP3 TIMP metallopeptidase inhibitor 3 20.0
LAMP5 lysosomal-associated membrane protein family, member 5 20.0
TNS2 tensin 2 20.0
PRCP prolylcarboxypeptidase (angiotensinase C) 20.0
POPDC2 popeye domain containing 2 20.0
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 20.0
AMPD3 adenosine monophosphate deaminase 3 20.0
PIEZO2 piezo-type mechanosensitive ion channel component 2 20.0
DHRS2 dehydrogenase/reductase (SDR family) member 2 20.0
BIRC3 baculoviral IAP repeat containing 3 20.0

decreased expression

Symbol Name Standardized Value
CPLX1 complexin 1 -20.0
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -20.0
TFB1M transcription factor B1, mitochondrial -20.0
FDPS farnesyl diphosphate synthase -20.0
ARHGAP33 Rho GTPase activating protein 33 -20.0
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -20.0
PACS1 phosphofurin acidic cluster sorting protein 1 -20.0
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -20.0
AKR1C3 aldo-keto reductase family 1, member C3 -20.0
LRRTM1 leucine rich repeat transmembrane neuronal 1 -20.0
ATF5 activating transcription factor 5 -20.0
PCDH7 protocadherin 7 -20.0
PHPT1 phosphohistidine phosphatase 1 -20.0
FAM216A family with sequence similarity 216, member A -20.0
NT5M 5',3'-nucleotidase, mitochondrial -20.0
FAM72D family with sequence similarity 72, member D -20.0
SEC24D SEC24 family member D -20.0
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 -20.0
DTNB dystrobrevin, beta -20.0
OXCT1 3-oxoacid CoA transferase 1 -20.0
EVL Enah/Vasp-like -20.0
USP25 ubiquitin specific peptidase 25 -20.0
YARS tyrosyl-tRNA synthetase -20.0
NAAA N-acylethanolamine acid amidase -20.0
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -20.0
ECI1 enoyl-CoA delta isomerase 1 -20.0
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -20.0
LTK leukocyte receptor tyrosine kinase -20.0
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -20.0
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -20.0
LAMA4 laminin, alpha 4 -20.0
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -20.0
CTH cystathionine gamma-lyase -20.0
LRP11 low density lipoprotein receptor-related protein 11 -20.0
MVD mevalonate (diphospho) decarboxylase -20.0
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -20.0
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I -20.0
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -20.0
HABP4 hyaluronan binding protein 4 -20.0
DOT1L DOT1-like histone H3K79 methyltransferase -20.0
IFI27L1 interferon, alpha-inducible protein 27-like 1 -20.0
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -20.0
FIGN fidgetin -20.0
AKNA AT-hook transcription factor -20.0
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit -20.0
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -20.0
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -20.0
REST RE1-silencing transcription factor -20.0
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -20.0
KIAA1958 KIAA1958 -20.0
MPLKIP M-phase specific PLK1 interacting protein -20.0
SMAD9 SMAD family member 9 -20.0
ENDOG endonuclease G -20.0
LINC00634 long intergenic non-protein coding RNA 634 -20.0
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -20.0
WWC2 WW and C2 domain containing 2 -20.0
DDIT3 DNA-damage-inducible transcript 3 -20.0
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -20.0
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -20.0
HSPA4L heat shock 70kDa protein 4-like -20.0
NCOA7 nuclear receptor coactivator 7 -20.0
NDE1 nudE neurodevelopment protein 1 -20.0
RELN reelin -20.0
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -20.0
IL15 interleukin 15 -20.0
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -20.0
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -20.0
DCAKD dephospho-CoA kinase domain containing -20.0
MMP17 matrix metallopeptidase 17 (membrane-inserted) -20.0
NRG1 neuregulin 1 -20.0
FAM72B family with sequence similarity 72, member B -20.0
FAM72A family with sequence similarity 72, member A -20.0
DEAF1 DEAF1 transcription factor -20.0
PRSS27 protease, serine 27 -20.0
TRIB3 tribbles pseudokinase 3 -20.0
RAVER2 ribonucleoprotein, PTB-binding 2 -20.0
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -20.0
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -20.0
MXD3 MAX dimerization protein 3 -20.0
USO1 USO1 vesicle transport factor -20.0
MECR mitochondrial trans-2-enoyl-CoA reductase -20.0
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -20.0
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -20.0
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -19.5229
HACD1 3-hydroxyacyl-CoA dehydratase 1 -19.5229
UIMC1 ubiquitin interaction motif containing 1 -19.5229
BTBD2 BTB (POZ) domain containing 2 -19.3979
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -19.301
AK7 adenylate kinase 7 -19.301
ATG10 autophagy related 10 -19.2218
C9ORF16 chromosome 9 open reading frame 16 -19.2218
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -18.9208
MAST2 microtubule associated serine/threonine kinase 2 -18.8539
STMN4 stathmin-like 4 -18.6198
TMEM120A transmembrane protein 120A -18.6021
SYT1 synaptotagmin I -18.5686
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit -18.3979
CRY2 cryptochrome circadian clock 2 -18.3468
LBH limb bud and heart development -18.2924
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -18.2518