Perturb_13930_OE_DLG2_ERP119345 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting DLG2 in neuroblastoma cell SH-SY5Y cell line (Study accession: ERP119345) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_13930_OE_DLG2_ERP119345 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 20.0
TNC tenascin C 20.0
TFPI2 tissue factor pathway inhibitor 2 20.0
BIRC3 baculoviral IAP repeat containing 3 20.0
BHLHE40 basic helix-loop-helix family, member e40 20.0
SFMBT2 Scm-like with four mbt domains 2 20.0
CCDC33 coiled-coil domain containing 33 20.0
LONRF2 LON peptidase N-terminal domain and ring finger 2 20.0
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 20.0
MMP24-AS1 MMP24 antisense RNA 1 20.0
MPG N-methylpurine-DNA glycosylase 20.0
THSD4 thrombospondin, type I, domain containing 4 20.0
GAP43 growth associated protein 43 20.0
PLXNA2 plexin A2 20.0
TRIB2 tribbles pseudokinase 2 20.0
SLIT2 slit homolog 2 (Drosophila) 20.0
NEFH neurofilament, heavy polypeptide 20.0
NEFM neurofilament, medium polypeptide 20.0
ARHGAP36 Rho GTPase activating protein 36 20.0
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 20.0
UNC13A unc-13 homolog A (C. elegans) 20.0
OPRM1 opioid receptor, mu 1 20.0
NFASC neurofascin 20.0
GPR39 G protein-coupled receptor 39 20.0
RNF144A ring finger protein 144A 20.0
C3 complement component 3 20.0
TBX3 T-box 3 20.0
SGK1 serum/glucocorticoid regulated kinase 1 20.0
RHOBTB3 Rho-related BTB domain containing 3 20.0
PTPRN protein tyrosine phosphatase, receptor type, N 20.0
MYT1L myelin transcription factor 1-like 20.0
COL4A1 collagen, type IV, alpha 1 20.0
COL4A2 collagen, type IV, alpha 2 20.0
FAM46A family with sequence similarity 46, member A 20.0
PDIA6 protein disulfide isomerase family A, member 6 20.0
IGLON5 IgLON family member 5 20.0
ECEL1 endothelin converting enzyme-like 1 20.0
OSBPL3 oxysterol binding protein-like 3 20.0
KIF1A kinesin family member 1A 20.0
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 20.0
IGFBP3 insulin-like growth factor binding protein 3 20.0
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 20.0
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 20.0
SV2C synaptic vesicle glycoprotein 2C 20.0
MEN1 multiple endocrine neoplasia I 20.0
PRKCA protein kinase C, alpha 20.0
LHFPL2 lipoma HMGIC fusion partner-like 2 20.0
HOOK2 hook microtubule-tethering protein 2 20.0
EGR1 early growth response 1 20.0
GLB1L2 galactosidase, beta 1-like 2 20.0
STRA6 stimulated by retinoic acid 6 20.0
NRCAM neuronal cell adhesion molecule 20.0
CTSB cathepsin B 20.0
CPLX2 complexin 2 20.0
VGF VGF nerve growth factor inducible 20.0
SYT7 synaptotagmin VII 20.0
B3GAT1 beta-1,3-glucuronyltransferase 1 20.0
PEG10 paternally expressed 10 20.0
CUX2 cut-like homeobox 2 20.0
DLG2 discs, large homolog 2 (Drosophila) 20.0
TMX4 thioredoxin-related transmembrane protein 4 20.0
NAP1L5 nucleosome assembly protein 1-like 5 20.0
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 20.0
UNC79 unc-79 homolog (C. elegans) 20.0
EML4 echinoderm microtubule associated protein like 4 20.0
FSTL5 follistatin-like 5 20.0
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 19.699
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 18.9586
VMP1 vacuole membrane protein 1 18.4949
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 18.2076
GAREM GRB2 associated, regulator of MAPK1 18.0706
PHF21B PHD finger protein 21B 17.5867
GOLGA7B golgin A7 family, member B 17.2041
NRXN2 neurexin 2 16.7073
TUBB4A tubulin, beta 4A class IVa 16.6012
RAB3C RAB3C, member RAS oncogene family 16.403
IGSF1 immunoglobulin superfamily, member 1 16.3977
RFPL1 ret finger protein-like 1 16.3696
RELN reelin 16.3439
TSHZ2 teashirt zinc finger homeobox 2 16.212
CRTAC1 cartilage acidic protein 1 15.7777
RIMS4 regulating synaptic membrane exocytosis 4 15.6297
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 15.5041
EDA2R ectodysplasin A2 receptor 15.3924
BEND4 BEN domain containing 4 15.1891
MARCH11 membrane-associated ring finger (C3HC4) 11 15.1807
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 15.0451
HMP19 HMP19 protein 14.9673
INA internexin neuronal intermediate filament protein, alpha 14.9275
KCNT1 potassium channel, sodium activated subfamily T, member 1 14.821
ELMO1 engulfment and cell motility 1 14.4382
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 14.4012
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 14.3914
COLEC11 collectin sub-family member 11 14.2534
VEGFA vascular endothelial growth factor A 14.0796
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 13.9633
GAL galanin/GMAP prepropeptide 13.8654
GBP2 guanylate binding protein 2, interferon-inducible 13.863
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 13.8195
SGCE sarcoglycan, epsilon 13.6685

decreased expression

Symbol Name Standardized Value
VASH1 vasohibin 1 -20.0
SARDH sarcosine dehydrogenase -20.0
TNS3 tensin 3 -20.0
NEUROG2 neurogenin 2 -20.0
COL3A1 collagen, type III, alpha 1 -20.0
PRDM8 PR domain containing 8 -20.0
CCDC80 coiled-coil domain containing 80 -20.0
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -20.0
MAGEA10 melanoma antigen family A10 -20.0
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -20.0
PDE3A phosphodiesterase 3A, cGMP-inhibited -20.0
CHGA chromogranin A -20.0
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -20.0
PTPRR protein tyrosine phosphatase, receptor type, R -20.0
NELL2 NEL-like 2 (chicken) -20.0
DACH1 dachshund family transcription factor 1 -20.0
INSM2 insulinoma-associated 2 -20.0
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -20.0
TBX18 T-box 18 -20.0
OPRD1 opioid receptor, delta 1 -20.0
FREM1 FRAS1 related extracellular matrix 1 -20.0
CRABP2 cellular retinoic acid binding protein 2 -20.0
SLC35E2B solute carrier family 35, member E2B -20.0
MAB21L2 mab-21-like 2 (C. elegans) -20.0
ARHGAP42 Rho GTPase activating protein 42 -20.0
TXNIP thioredoxin interacting protein -20.0
IGF2 insulin-like growth factor 2 -20.0
PDZRN3 PDZ domain containing ring finger 3 -19.5229
MOXD1 monooxygenase, DBH-like 1 -19.2218
CAMK4 calcium/calmodulin-dependent protein kinase IV -19.0969
RAB27B RAB27B, member RAS oncogene family -18.9586
PRPH peripherin -18.9586
NANOS1 nanos homolog 1 (Drosophila) -18.9586
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -18.6198
SESN3 sestrin 3 -17.6126
TGM2 transglutaminase 2 -17.1739
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 -15.7365
KIRREL kin of IRRE like (Drosophila) -15.6583
TBC1D2B TBC1 domain family, member 2B -15.6014
NREP neuronal regeneration related protein -15.5014
SFRP1 secreted frizzled-related protein 1 -15.488
ISL1 ISL LIM homeobox 1 -14.8034
PTPRB protein tyrosine phosphatase, receptor type, B -14.6583
YAP1 Yes-associated protein 1 -14.4564
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -14.2508
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -14.2047
PTER phosphotriesterase related -13.5961
EFNB2 ephrin-B2 -13.5718
LHX9 LIM homeobox 9 -13.5372
CHRM3 cholinergic receptor, muscarinic 3 -13.475
PPP1R12B protein phosphatase 1, regulatory subunit 12B -13.3895
ANTXR2 anthrax toxin receptor 2 -13.0881
TRIM56 tripartite motif containing 56 -13.0748
HIST1H4I histone cluster 1, H4i -13.0375
CLSTN2 calsyntenin 2 -13.0309
NARFL nuclear prelamin A recognition factor-like -12.4332
ALX3 ALX homeobox 3 -12.3582
FRMD4B FERM domain containing 4B -11.9579
MAPK7 mitogen-activated protein kinase 7 -11.703
VCAN versican -11.5559
TRIL TLR4 interactor with leucine-rich repeats -10.8051
CORIN corin, serine peptidase -10.6422
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 -10.4013
C11ORF96 chromosome 11 open reading frame 96 -10.2428
C14ORF166 chromosome 14 open reading frame 166 -10.2193
STARD4 StAR-related lipid transfer (START) domain containing 4 -9.80409
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -9.58941
MTMR11 myotubularin related protein 11 -9.4637
EYA4 EYA transcriptional coactivator and phosphatase 4 -9.4322
IL3RA interleukin 3 receptor, alpha (low affinity) -9.37494
CHDH choline dehydrogenase -9.19932
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) -9.14682
ANKRD34A ankyrin repeat domain 34A -8.95857
SLC35D3 solute carrier family 35, member D3 -8.90361
CYB5R2 cytochrome b5 reductase 2 -8.78107
BMPR1B bone morphogenetic protein receptor, type IB -8.72506
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -8.72169
CNTN3 contactin 3 (plasmacytoma associated) -8.50632
TOX thymocyte selection-associated high mobility group box -8.48274
NEBL nebulette -8.41476
ATXN1 ataxin 1 -8.3941
CDC37L1 cell division cycle 37-like 1 -8.3547
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -8.28357
FBXO8 F-box protein 8 -8.11938
DNAH11 dynein, axonemal, heavy chain 11 -7.97586
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -7.94947
CDK11B cyclin-dependent kinase 11B -7.89052
NUB1 negative regulator of ubiquitin-like proteins 1 -7.8763
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 -7.8487
TBPL1 TBP-like 1 -7.80875
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 -7.77255
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -7.66933
TACC2 transforming, acidic coiled-coil containing protein 2 -7.57498
LTBP1 latent transforming growth factor beta binding protein 1 -7.56891
LSP1 lymphocyte-specific protein 1 -7.40883
FN1 fibronectin 1 -7.40678
MFAP4 microfibrillar-associated protein 4 -7.36529
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -7.26481
KRT86 keratin 86, type II -7.22385
IL20RA interleukin 20 receptor, alpha -7.12252