| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting DLG2 in neuroblastoma cell SH-SY5Y cell line (Study accession: ERP119345) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_13930_OE_DLG2_ERP119345 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 20.0 |
| TNC | tenascin C | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| BIRC3 | baculoviral IAP repeat containing 3 | 20.0 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 20.0 |
| SFMBT2 | Scm-like with four mbt domains 2 | 20.0 |
| CCDC33 | coiled-coil domain containing 33 | 20.0 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 20.0 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 20.0 |
| MMP24-AS1 | MMP24 antisense RNA 1 | 20.0 |
| MPG | N-methylpurine-DNA glycosylase | 20.0 |
| THSD4 | thrombospondin, type I, domain containing 4 | 20.0 |
| GAP43 | growth associated protein 43 | 20.0 |
| PLXNA2 | plexin A2 | 20.0 |
| TRIB2 | tribbles pseudokinase 2 | 20.0 |
| SLIT2 | slit homolog 2 (Drosophila) | 20.0 |
| NEFH | neurofilament, heavy polypeptide | 20.0 |
| NEFM | neurofilament, medium polypeptide | 20.0 |
| ARHGAP36 | Rho GTPase activating protein 36 | 20.0 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 20.0 |
| UNC13A | unc-13 homolog A (C. elegans) | 20.0 |
| OPRM1 | opioid receptor, mu 1 | 20.0 |
| NFASC | neurofascin | 20.0 |
| GPR39 | G protein-coupled receptor 39 | 20.0 |
| RNF144A | ring finger protein 144A | 20.0 |
| C3 | complement component 3 | 20.0 |
| TBX3 | T-box 3 | 20.0 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 20.0 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 20.0 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | 20.0 |
| MYT1L | myelin transcription factor 1-like | 20.0 |
| COL4A1 | collagen, type IV, alpha 1 | 20.0 |
| COL4A2 | collagen, type IV, alpha 2 | 20.0 |
| FAM46A | family with sequence similarity 46, member A | 20.0 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 20.0 |
| IGLON5 | IgLON family member 5 | 20.0 |
| ECEL1 | endothelin converting enzyme-like 1 | 20.0 |
| OSBPL3 | oxysterol binding protein-like 3 | 20.0 |
| KIF1A | kinesin family member 1A | 20.0 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 20.0 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 20.0 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 20.0 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 20.0 |
| SV2C | synaptic vesicle glycoprotein 2C | 20.0 |
| MEN1 | multiple endocrine neoplasia I | 20.0 |
| PRKCA | protein kinase C, alpha | 20.0 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 20.0 |
| HOOK2 | hook microtubule-tethering protein 2 | 20.0 |
| EGR1 | early growth response 1 | 20.0 |
| GLB1L2 | galactosidase, beta 1-like 2 | 20.0 |
| STRA6 | stimulated by retinoic acid 6 | 20.0 |
| NRCAM | neuronal cell adhesion molecule | 20.0 |
| CTSB | cathepsin B | 20.0 |
| CPLX2 | complexin 2 | 20.0 |
| VGF | VGF nerve growth factor inducible | 20.0 |
| SYT7 | synaptotagmin VII | 20.0 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 | 20.0 |
| PEG10 | paternally expressed 10 | 20.0 |
| CUX2 | cut-like homeobox 2 | 20.0 |
| DLG2 | discs, large homolog 2 (Drosophila) | 20.0 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 20.0 |
| NAP1L5 | nucleosome assembly protein 1-like 5 | 20.0 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 20.0 |
| UNC79 | unc-79 homolog (C. elegans) | 20.0 |
| EML4 | echinoderm microtubule associated protein like 4 | 20.0 |
| FSTL5 | follistatin-like 5 | 20.0 |
| PLCXD3 | phosphatidylinositol-specific phospholipase C, X domain containing 3 | 19.699 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 18.9586 |
| VMP1 | vacuole membrane protein 1 | 18.4949 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 18.2076 |
| GAREM | GRB2 associated, regulator of MAPK1 | 18.0706 |
| PHF21B | PHD finger protein 21B | 17.5867 |
| GOLGA7B | golgin A7 family, member B | 17.2041 |
| NRXN2 | neurexin 2 | 16.7073 |
| TUBB4A | tubulin, beta 4A class IVa | 16.6012 |
| RAB3C | RAB3C, member RAS oncogene family | 16.403 |
| IGSF1 | immunoglobulin superfamily, member 1 | 16.3977 |
| RFPL1 | ret finger protein-like 1 | 16.3696 |
| RELN | reelin | 16.3439 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 16.212 |
| CRTAC1 | cartilage acidic protein 1 | 15.7777 |
| RIMS4 | regulating synaptic membrane exocytosis 4 | 15.6297 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 15.5041 |
| EDA2R | ectodysplasin A2 receptor | 15.3924 |
| BEND4 | BEN domain containing 4 | 15.1891 |
| MARCH11 | membrane-associated ring finger (C3HC4) 11 | 15.1807 |
| NAT16 | N-acetyltransferase 16 (GCN5-related, putative) | 15.0451 |
| HMP19 | HMP19 protein | 14.9673 |
| INA | internexin neuronal intermediate filament protein, alpha | 14.9275 |
| KCNT1 | potassium channel, sodium activated subfamily T, member 1 | 14.821 |
| ELMO1 | engulfment and cell motility 1 | 14.4382 |
| SLC8A3 | solute carrier family 8 (sodium/calcium exchanger), member 3 | 14.4012 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 14.3914 |
| COLEC11 | collectin sub-family member 11 | 14.2534 |
| VEGFA | vascular endothelial growth factor A | 14.0796 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 13.9633 |
| GAL | galanin/GMAP prepropeptide | 13.8654 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 13.863 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 13.8195 |
| SGCE | sarcoglycan, epsilon | 13.6685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VASH1 | vasohibin 1 | -20.0 |
| SARDH | sarcosine dehydrogenase | -20.0 |
| TNS3 | tensin 3 | -20.0 |
| NEUROG2 | neurogenin 2 | -20.0 |
| COL3A1 | collagen, type III, alpha 1 | -20.0 |
| PRDM8 | PR domain containing 8 | -20.0 |
| CCDC80 | coiled-coil domain containing 80 | -20.0 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -20.0 |
| MAGEA10 | melanoma antigen family A10 | -20.0 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -20.0 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -20.0 |
| CHGA | chromogranin A | -20.0 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -20.0 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -20.0 |
| NELL2 | NEL-like 2 (chicken) | -20.0 |
| DACH1 | dachshund family transcription factor 1 | -20.0 |
| INSM2 | insulinoma-associated 2 | -20.0 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -20.0 |
| TBX18 | T-box 18 | -20.0 |
| OPRD1 | opioid receptor, delta 1 | -20.0 |
| FREM1 | FRAS1 related extracellular matrix 1 | -20.0 |
| CRABP2 | cellular retinoic acid binding protein 2 | -20.0 |
| SLC35E2B | solute carrier family 35, member E2B | -20.0 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -20.0 |
| ARHGAP42 | Rho GTPase activating protein 42 | -20.0 |
| TXNIP | thioredoxin interacting protein | -20.0 |
| IGF2 | insulin-like growth factor 2 | -20.0 |
| PDZRN3 | PDZ domain containing ring finger 3 | -19.5229 |
| MOXD1 | monooxygenase, DBH-like 1 | -19.2218 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | -19.0969 |
| RAB27B | RAB27B, member RAS oncogene family | -18.9586 |
| PRPH | peripherin | -18.9586 |
| NANOS1 | nanos homolog 1 (Drosophila) | -18.9586 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -18.6198 |
| SESN3 | sestrin 3 | -17.6126 |
| TGM2 | transglutaminase 2 | -17.1739 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -15.7365 |
| KIRREL | kin of IRRE like (Drosophila) | -15.6583 |
| TBC1D2B | TBC1 domain family, member 2B | -15.6014 |
| NREP | neuronal regeneration related protein | -15.5014 |
| SFRP1 | secreted frizzled-related protein 1 | -15.488 |
| ISL1 | ISL LIM homeobox 1 | -14.8034 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -14.6583 |
| YAP1 | Yes-associated protein 1 | -14.4564 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -14.2508 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -14.2047 |
| PTER | phosphotriesterase related | -13.5961 |
| EFNB2 | ephrin-B2 | -13.5718 |
| LHX9 | LIM homeobox 9 | -13.5372 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -13.475 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -13.3895 |
| ANTXR2 | anthrax toxin receptor 2 | -13.0881 |
| TRIM56 | tripartite motif containing 56 | -13.0748 |
| HIST1H4I | histone cluster 1, H4i | -13.0375 |
| CLSTN2 | calsyntenin 2 | -13.0309 |
| NARFL | nuclear prelamin A recognition factor-like | -12.4332 |
| ALX3 | ALX homeobox 3 | -12.3582 |
| FRMD4B | FERM domain containing 4B | -11.9579 |
| MAPK7 | mitogen-activated protein kinase 7 | -11.703 |
| VCAN | versican | -11.5559 |
| TRIL | TLR4 interactor with leucine-rich repeats | -10.8051 |
| CORIN | corin, serine peptidase | -10.6422 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | -10.4013 |
| C11ORF96 | chromosome 11 open reading frame 96 | -10.2428 |
| C14ORF166 | chromosome 14 open reading frame 166 | -10.2193 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -9.80409 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -9.58941 |
| MTMR11 | myotubularin related protein 11 | -9.4637 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | -9.4322 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) | -9.37494 |
| CHDH | choline dehydrogenase | -9.19932 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) | -9.14682 |
| ANKRD34A | ankyrin repeat domain 34A | -8.95857 |
| SLC35D3 | solute carrier family 35, member D3 | -8.90361 |
| CYB5R2 | cytochrome b5 reductase 2 | -8.78107 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -8.72506 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -8.72169 |
| CNTN3 | contactin 3 (plasmacytoma associated) | -8.50632 |
| TOX | thymocyte selection-associated high mobility group box | -8.48274 |
| NEBL | nebulette | -8.41476 |
| ATXN1 | ataxin 1 | -8.3941 |
| CDC37L1 | cell division cycle 37-like 1 | -8.3547 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -8.28357 |
| FBXO8 | F-box protein 8 | -8.11938 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -7.97586 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -7.94947 |
| CDK11B | cyclin-dependent kinase 11B | -7.89052 |
| NUB1 | negative regulator of ubiquitin-like proteins 1 | -7.8763 |
| AIFM2 | apoptosis-inducing factor, mitochondrion-associated, 2 | -7.8487 |
| TBPL1 | TBP-like 1 | -7.80875 |
| IGDCC3 | immunoglobulin superfamily, DCC subclass, member 3 | -7.77255 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | -7.66933 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -7.57498 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -7.56891 |
| LSP1 | lymphocyte-specific protein 1 | -7.40883 |
| FN1 | fibronectin 1 | -7.40678 |
| MFAP4 | microfibrillar-associated protein 4 | -7.36529 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -7.26481 |
| KRT86 | keratin 86, type II | -7.22385 |
| IL20RA | interleukin 20 receptor, alpha | -7.12252 |