| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting RNU11 in neuron cell (Study accession: SRP178463) (PerturbAtlas) |
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190 genes differentially expressed following the Perturb_13978_OE_RNU11_SRP178463 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 | 10.7747 |
| FLT1 | fms-related tyrosine kinase 1 | 10.2762 |
| ADAM19 | ADAM metallopeptidase domain 19 | 9.68813 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 8.50923 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 8.08863 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 7.41627 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 7.11916 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | 6.35757 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 6.02831 |
| MEDAG | mesenteric estrogen-dependent adipogenesis | 5.97838 |
| LOX | lysyl oxidase | 5.6798 |
| MFAP2 | microfibrillar-associated protein 2 | 5.039 |
| NOTCH3 | notch 3 | 4.8024 |
| TAGLN2 | transgelin 2 | 4.57731 |
| NEK7 | NIMA-related kinase 7 | 4.50568 |
| SOX9 | SRY (sex determining region Y)-box 9 | 4.44288 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 | 4.42202 |
| MFAP5 | microfibrillar associated protein 5 | 4.35152 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 4.00056 |
| ANPEP | alanyl (membrane) aminopeptidase | 3.7767 |
| CD44 | CD44 molecule (Indian blood group) | 3.77165 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 3.77165 |
| GPR68 | G protein-coupled receptor 68 | 3.53271 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 3.32495 |
| LAMB3 | laminin, beta 3 | 3.24812 |
| PEAR1 | platelet endothelial aggregation receptor 1 | 3.18308 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.16345 |
| ANGPT2 | angiopoietin 2 | 3.00579 |
| ADAMTSL1 | ADAMTS-like 1 | 2.97169 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | 2.96827 |
| SMTN | smoothelin | 2.9524 |
| KIAA1549L | KIAA1549-like | 2.9524 |
| ENG | endoglin | 2.85902 |
| SH2D3C | SH2 domain containing 3C | 2.83208 |
| ZNF703 | zinc finger protein 703 | 2.66323 |
| TAGLN | transgelin | 2.637 |
| OSMR | oncostatin M receptor | 2.58955 |
| PLXNA4 | plexin A4 | 2.56519 |
| WISP1 | WNT1 inducible signaling pathway protein 1 | 2.5467 |
| SLC35E4 | solute carrier family 35, member E4 | 2.54115 |
| GLIPR1 | GLI pathogenesis-related 1 | 2.51517 |
| NOTCH1 | notch 1 | 2.50654 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 2.46589 |
| MARCKSL1 | MARCKS-like 1 | 2.46589 |
| MMP28 | matrix metallopeptidase 28 | 2.43769 |
| HMGA2 | high mobility group AT-hook 2 | 2.42428 |
| PROCR | protein C receptor, endothelial | 2.37401 |
| KIFC3 | kinesin family member C3 | 2.31348 |
| SPHK1 | sphingosine kinase 1 | 2.28006 |
| NDRG1 | N-myc downstream regulated 1 | 2.13734 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 2.05329 |
| NAV1 | neuron navigator 1 | 2.02517 |
| STX1B | syntaxin 1B | 1.9862 |
| XYLT1 | xylosyltransferase I | 1.9442 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 1.92601 |
| HES1 | hes family bHLH transcription factor 1 | 1.88505 |
| VEGFC | vascular endothelial growth factor C | 1.88428 |
| FZD7 | frizzled class receptor 7 | 1.88428 |
| PLAT | plasminogen activator, tissue | 1.85618 |
| GMNN | geminin, DNA replication inhibitor | 1.83464 |
| CCDC80 | coiled-coil domain containing 80 | 1.82477 |
| ARSI | arylsulfatase family, member I | 1.79664 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 1.76703 |
| ITGA1 | integrin, alpha 1 | 1.76456 |
| FOXC2 | forkhead box C2 | 1.76163 |
| POSTN | periostin, osteoblast specific factor | 1.75873 |
| KIF21B | kinesin family member 21B | 1.74301 |
| FZD8 | frizzled class receptor 8 | 1.74124 |
| TEK | TEK tyrosine kinase, endothelial | 1.73612 |
| LRRC17 | leucine rich repeat containing 17 | 1.67084 |
| LDHA | lactate dehydrogenase A | 1.66373 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 1.58649 |
| RAB17 | RAB17, member RAS oncogene family | 1.5637 |
| DIAPH1 | diaphanous-related formin 1 | 1.53578 |
| QPCT | glutaminyl-peptide cyclotransferase | 1.53578 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 1.53342 |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 | 1.46963 |
| GRIP2 | glutamate receptor interacting protein 2 | 1.46495 |
| TUBA1A | tubulin, alpha 1a | 1.44809 |
| SYNPO | synaptopodin | 1.44399 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 1.44399 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 1.44399 |
| COTL1 | coactosin-like F-actin binding protein 1 | 1.40835 |
| SGK223 | homolog of rat pragma of Rnd2 | 1.37041 |
| C6ORF132 | chromosome 6 open reading frame 132 | 1.37041 |
| SULF1 | sulfatase 1 | 1.36366 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 1.36366 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 1.3552 |
| RAPGEF3 | Rap guanine nucleotide exchange factor (GEF) 3 | 1.35103 |
| LXN | latexin | 1.34304 |
| PTGES | prostaglandin E synthase | 1.33401 |
| KLHL4 | kelch-like family member 4 | 1.31521 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 1.3151 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | 1.3151 |
| CYP27C1 | cytochrome P450, family 27, subfamily C, polypeptide 1 | 1.30696 |
| SOD3 | superoxide dismutase 3, extracellular | 1.30346 |
| ALCAM | activated leukocyte cell adhesion molecule | 1.30263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADA | adenosine deaminase | -9.87738 |
| FTH1 | ferritin, heavy polypeptide 1 | -8.74595 |
| L1CAM | L1 cell adhesion molecule | -7.41627 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -7.15227 |
| KLF9 | Kruppel-like factor 9 | -6.02831 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -5.97838 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | -5.937 |
| DDIT4 | DNA-damage-inducible transcript 4 | -5.6798 |
| TP53I11 | tumor protein p53 inducible protein 11 | -5.42997 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -5.34536 |
| DUSP27 | dual specificity phosphatase 27 (putative) | -5.24886 |
| MMP11 | matrix metallopeptidase 11 | -5.24886 |
| LCNL1 | lipocalin-like 1 | -4.86271 |
| ACKR3 | atypical chemokine receptor 3 | -4.68871 |
| ACVR1C | activin A receptor, type IC | -4.60967 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -4.51157 |
| FTL | ferritin, light polypeptide | -4.50568 |
| CTSH | cathepsin H | -3.31315 |
| TFRC | transferrin receptor | -3.04234 |
| GPNMB | glycoprotein (transmembrane) nmb | -2.91132 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -2.87065 |
| TAPBPL | TAP binding protein-like | -2.76797 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | -2.75165 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | -2.71063 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -2.637 |
| ANGPT1 | angiopoietin 1 | -2.62915 |
| SLC25A29 | solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 | -2.61135 |
| SHISA9 | shisa family member 9 | -2.60125 |
| NHLRC3 | NHL repeat containing 3 | -2.59682 |
| CLEC3B | C-type lectin domain family 3, member B | -2.58955 |
| TENM2 | teneurin transmembrane protein 2 | -2.5886 |
| MEGF9 | multiple EGF-like-domains 9 | -2.43048 |
| CTSL | cathepsin L | -2.40674 |
| UNC5D | unc-5 homolog D (C. elegans) | -2.37318 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -2.28276 |
| ALOX5 | arachidonate 5-lipoxygenase | -2.28006 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | -2.2553 |
| IL34 | interleukin 34 | -2.22277 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | -2.13199 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.09005 |
| HAVCR2 | hepatitis A virus cellular receptor 2 | -2.06023 |
| MOSPD2 | motile sperm domain containing 2 | -2.02194 |
| DBP | D site of albumin promoter (albumin D-box) binding protein | -1.98987 |
| SLC16A14 | solute carrier family 16, member 14 | -1.98411 |
| MYBPC2 | myosin binding protein C, fast type | -1.9536 |
| CTSK | cathepsin K | -1.9442 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -1.9442 |
| TNFAIP8L3 | tumor necrosis factor, alpha-induced protein 8-like 3 | -1.88428 |
| TRIM9 | tripartite motif containing 9 | -1.87723 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -1.80849 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -1.79033 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -1.74301 |
| CCND3 | cyclin D3 | -1.74301 |
| KLHL41 | kelch-like family member 41 | -1.74301 |
| KLF13 | Kruppel-like factor 13 | -1.74301 |
| SLC16A6 | solute carrier family 16, member 6 | -1.71611 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -1.69866 |
| AMDHD2 | amidohydrolase domain containing 2 | -1.6748 |
| ANTXR1 | anthrax toxin receptor 1 | -1.66759 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 | -1.65933 |
| TCN2 | transcobalamin II | -1.65054 |
| KLHL24 | kelch-like family member 24 | -1.64965 |
| STEAP4 | STEAP family member 4 | -1.63449 |
| DPP7 | dipeptidyl-peptidase 7 | -1.61181 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -1.59143 |
| RAB39B | RAB39B, member RAS oncogene family | -1.58662 |
| FZD5 | frizzled class receptor 5 | -1.58649 |
| CMTM3 | CKLF-like MARVEL transmembrane domain containing 3 | -1.564 |
| FAM111A | family with sequence similarity 111, member A | -1.564 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit | -1.56007 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -1.55936 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -1.55469 |
| PAPLN | papilin, proteoglycan-like sulfated glycoprotein | -1.53578 |
| WSB1 | WD repeat and SOCS box containing 1 | -1.52827 |
| WEE1 | WEE1 G2 checkpoint kinase | -1.50316 |
| RGS11 | regulator of G-protein signaling 11 | -1.48373 |
| OLFML2A | olfactomedin-like 2A | -1.48361 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -1.47927 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -1.4522 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | -1.4481 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -1.43971 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -1.43674 |
| FLCN | folliculin | -1.41064 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 | -1.40835 |
| ASS1 | argininosuccinate synthase 1 | -1.39243 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -1.37041 |
| CD34 | CD34 molecule | -1.37041 |
| S100A3 | S100 calcium binding protein A3 | -1.3552 |
| TMEM194A | transmembrane protein 194A | -1.35103 |
| FAM107A | family with sequence similarity 107, member A | -1.31365 |
| SERINC5 | serine incorporator 5 | -1.31365 |
| ACVR2A | activin A receptor, type IIA | -1.30696 |
| RFTN1 | raftlin, lipid raft linker 1 | -1.30696 |