| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Mut perturbation targeting LST8 in Non-small cell lung cancer(H1299) cell line (Study accession: SRP330127) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_14087_Mut_LST8_SRP330127 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMC1A | structural maintenance of chromosomes 1A | 20.0 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 20.0 |
| EIF5A | eukaryotic translation initiation factor 5A | 20.0 |
| TUBB6 | tubulin, beta 6 class V | 20.0 |
| MACF1 | microtubule-actin crosslinking factor 1 | 20.0 |
| TCP1 | t-complex 1 | 20.0 |
| TUBB4B | tubulin, beta 4B class IVb | 20.0 |
| MCM7 | minichromosome maintenance complex component 7 | 20.0 |
| MCM4 | minichromosome maintenance complex component 4 | 20.0 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 20.0 |
| TM4SF1 | transmembrane 4 L six family member 1 | 20.0 |
| KHSRP | KH-type splicing regulatory protein | 20.0 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 20.0 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 20.0 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 20.0 |
| TPM3 | tropomyosin 3 | 20.0 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 20.0 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 20.0 |
| MKI67 | marker of proliferation Ki-67 | 20.0 |
| EIF5 | eukaryotic translation initiation factor 5 | 20.0 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 20.0 |
| RBMX | RNA binding motif protein, X-linked | 20.0 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 20.0 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 20.0 |
| KPNB1 | karyopherin (importin) beta 1 | 20.0 |
| ACTG1 | actin gamma 1 | 20.0 |
| ANLN | anillin, actin binding protein | 20.0 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 20.0 |
| CAPRIN1 | cell cycle associated protein 1 | 20.0 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 20.0 |
| MYOF | myoferlin | 20.0 |
| TUBB2A | tubulin, beta 2A class IIa | 20.0 |
| SFPQ | splicing factor proline/glutamine-rich | 20.0 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 20.0 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 20.0 |
| VDAC1 | voltage-dependent anion channel 1 | 20.0 |
| MORF4L2 | mortality factor 4 like 2 | 20.0 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 20.0 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 20.0 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 20.0 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 20.0 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 20.0 |
| PTMA | prothymosin, alpha | 20.0 |
| LDHA | lactate dehydrogenase A | 20.0 |
| CFL1 | cofilin 1 (non-muscle) | 20.0 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 20.0 |
| NCL | nucleolin | 20.0 |
| FOSL1 | FOS-like antigen 1 | 20.0 |
| CD44 | CD44 molecule (Indian blood group) | 20.0 |
| JADE2 | jade family PHD finger 2 | 20.0 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 20.0 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 20.0 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 20.0 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 20.0 |
| RAN | RAN, member RAS oncogene family | 20.0 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 20.0 |
| EMP1 | epithelial membrane protein 1 | 20.0 |
| WDR1 | WD repeat domain 1 | 20.0 |
| CKAP5 | cytoskeleton associated protein 5 | 20.0 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 20.0 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 20.0 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 20.0 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 20.0 |
| YBX1 | Y box binding protein 1 | 20.0 |
| ITGA6 | integrin, alpha 6 | 20.0 |
| ENO1 | enolase 1, (alpha) | 20.0 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 20.0 |
| CCNA2 | cyclin A2 | 20.0 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 20.0 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 20.0 |
| ACTN4 | actinin, alpha 4 | 20.0 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 20.0 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 | 20.0 |
| SLC38A2 | solute carrier family 38, member 2 | 20.0 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 20.0 |
| FLNA | filamin A, alpha | 20.0 |
| HMGB1 | high mobility group box 1 | 20.0 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 20.0 |
| ANXA1 | annexin A1 | 20.0 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 20.0 |
| HMGA2 | high mobility group AT-hook 2 | 20.0 |
| XPO1 | exportin 1 | 20.0 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 20.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | 20.0 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 20.0 |
| TPX2 | TPX2, microtubule-associated | 20.0 |
| PTBP1 | polypyrimidine tract binding protein 1 | 20.0 |
| NONO | non-POU domain containing, octamer-binding | 20.0 |
| PKM | pyruvate kinase, muscle | 20.0 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | 20.0 |
| LDLR | low density lipoprotein receptor | 20.0 |
| LMNA | lamin A/C | 20.0 |
| LMNB2 | lamin B2 | 20.0 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 20.0 |
| SSFA2 | sperm specific antigen 2 | 20.0 |
| IPO5 | importin 5 | 20.0 |
| RAD21 | RAD21 homolog (S. pombe) | 20.0 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor | 20.0 |
| ACTB | actin, beta | 20.0 |
| SMS | spermine synthase | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NATD1 | N-acetyltransferase domain containing 1 | -20.0 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | -20.0 |
| SPEG | SPEG complex locus | -20.0 |
| ENGASE | endo-beta-N-acetylglucosaminidase | -20.0 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -20.0 |
| FBXO2 | F-box protein 2 | -20.0 |
| PAPPA2 | pappalysin 2 | -20.0 |
| ADTRP | androgen-dependent TFPI-regulating protein | -20.0 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -20.0 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -20.0 |
| TTC39A | tetratricopeptide repeat domain 39A | -20.0 |
| TUBG2 | tubulin, gamma 2 | -20.0 |
| SPX | spexin hormone | -20.0 |
| ASS1 | argininosuccinate synthase 1 | -20.0 |
| LTB4R | leukotriene B4 receptor | -20.0 |
| TMEM8B | transmembrane protein 8B | -20.0 |
| SLC25A27 | solute carrier family 25, member 27 | -20.0 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -20.0 |
| SLIT1 | slit homolog 1 (Drosophila) | -20.0 |
| STK32A | serine/threonine kinase 32A | -20.0 |
| OLFML2A | olfactomedin-like 2A | -20.0 |
| SDC3 | syndecan 3 | -20.0 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic | -20.0 |
| SYNGR1 | synaptogyrin 1 | -20.0 |
| DMGDH | dimethylglycine dehydrogenase | -20.0 |
| ANKRD24 | ankyrin repeat domain 24 | -20.0 |
| DMKN | dermokine | -20.0 |
| ASIC1 | acid sensing (proton gated) ion channel 1 | -20.0 |
| CCND2 | cyclin D2 | -20.0 |
| NGEF | neuronal guanine nucleotide exchange factor | -20.0 |
| VWA5A | von Willebrand factor A domain containing 5A | -20.0 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -20.0 |
| GIPR | gastric inhibitory polypeptide receptor | -20.0 |
| AKNA | AT-hook transcription factor | -20.0 |
| HTRA1 | HtrA serine peptidase 1 | -20.0 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -20.0 |
| CLSTN3 | calsyntenin 3 | -20.0 |
| CCDC92 | coiled-coil domain containing 92 | -20.0 |
| MIB2 | mindbomb E3 ubiquitin protein ligase 2 | -20.0 |
| RNF212 | ring finger protein 212 | -20.0 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -20.0 |
| GPR160 | G protein-coupled receptor 160 | -20.0 |
| CAPN12 | calpain 12 | -20.0 |
| PEX6 | peroxisomal biogenesis factor 6 | -20.0 |
| GGT7 | gamma-glutamyltransferase 7 | -20.0 |
| TLE2 | transducin-like enhancer of split 2 | -20.0 |
| GAS6 | growth arrest-specific 6 | -20.0 |
| CLGN | calmegin | -20.0 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -20.0 |
| SELM | selenoprotein M | -20.0 |
| TRAPPC6A | trafficking protein particle complex 6A | -20.0 |
| ALS2CL | ALS2 C-terminal like | -20.0 |
| ADSSL1 | adenylosuccinate synthase like 1 | -20.0 |
| RNASET2 | ribonuclease T2 | -20.0 |
| CYS1 | cystin 1 | -20.0 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -20.0 |
| SCRN2 | secernin 2 | -20.0 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -20.0 |
| HSPA1B | heat shock 70kDa protein 1B | -20.0 |
| CLTCL1 | clathrin, heavy chain-like 1 | -20.0 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | -20.0 |
| RELN | reelin | -20.0 |
| MAPT | microtubule-associated protein tau | -20.0 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -20.0 |
| MACROD1 | MACRO domain containing 1 | -20.0 |
| SYT1 | synaptotagmin I | -20.0 |
| TRNP1 | TMF1-regulated nuclear protein 1 | -20.0 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase | -20.0 |
| ABLIM3 | actin binding LIM protein family, member 3 | -20.0 |
| FAM102A | family with sequence similarity 102, member A | -20.0 |
| PRUNE2 | prune homolog 2 (Drosophila) | -20.0 |
| MYO15B | myosin XVB | -20.0 |
| TSPYL2 | TSPY-like 2 | -20.0 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -20.0 |
| TSLP | thymic stromal lymphopoietin | -20.0 |
| PCYOX1L | prenylcysteine oxidase 1 like | -20.0 |
| C1RL | complement component 1, r subcomponent-like | -20.0 |
| MST1 | macrophage stimulating 1 | -20.0 |
| MMP2 | matrix metallopeptidase 2 | -20.0 |
| MOXD1 | monooxygenase, DBH-like 1 | -20.0 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 | -20.0 |
| TLCD2 | TLC domain containing 2 | -20.0 |
| LAMP3 | lysosomal-associated membrane protein 3 | -20.0 |
| BCAS4 | breast carcinoma amplified sequence 4 | -20.0 |
| PORCN | porcupine homolog (Drosophila) | -20.0 |
| REEP2 | receptor accessory protein 2 | -20.0 |
| GSAP | gamma-secretase activating protein | -20.0 |
| RABL3 | RAB, member of RAS oncogene family-like 3 | -20.0 |
| CSAD | cysteine sulfinic acid decarboxylase | -20.0 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -20.0 |
| ZFAND2A | zinc finger, AN1-type domain 2A | -20.0 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -20.0 |
| MR1 | major histocompatibility complex, class I-related | -20.0 |
| PCED1A | PC-esterase domain containing 1A | -20.0 |
| DPEP3 | dipeptidase 3 | -20.0 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -20.0 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -20.0 |
| ACBD4 | acyl-CoA binding domain containing 4 | -20.0 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -20.0 |
| ATP6V0D2 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 | -20.0 |
