Perturb_14096_KD_HMGN3_DRP007117 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting HMGN3 in normal blie duct cell MMNK-1 cell line (Study accession: DRP007117) (PerturbAtlas)
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Genes

57 genes differentially expressed following the Perturb_14096_KD_HMGN3_DRP007117 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
TPM4 tropomyosin 4 8.46397
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 4.8341
OGFR opioid growth factor receptor 4.15478
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.21292
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 3.06076
MESDC2 mesoderm development candidate 2 2.92707
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 2.8597
MME membrane metallo-endopeptidase 2.66861
TSC22D1 TSC22 domain family, member 1 2.65885
ZNF721 zinc finger protein 721 2.5768
HPCAL4 hippocalcin like 4 2.54936
C1QTNF6 C1q and tumor necrosis factor related protein 6 2.51957
MAP1B microtubule-associated protein 1B 2.37608
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.29245
MAP7D2 MAP7 domain containing 2 1.83293
SETD7 SET domain containing (lysine methyltransferase) 7 1.81999
BICD2 bicaudal D homolog 2 (Drosophila) 1.81999
KCTD17 potassium channel tetramerization domain containing 17 1.81999
ZNF678 zinc finger protein 678 1.72126
DCBLD2 discoidin, CUB and LCCL domain containing 2 1.69669
NOLC1 nucleolar and coiled-body phosphoprotein 1 1.69669
DPYSL2 dihydropyrimidinase-like 2 1.66346
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 1.61033
F2R coagulation factor II (thrombin) receptor 1.51815
ZNF675 zinc finger protein 675 1.41492
RGS19 regulator of G-protein signaling 19 1.36705

decreased expression

Symbol Name Standardized Value
HMGN3 high mobility group nucleosomal binding domain 3 -20.0
MORN2 MORN repeat containing 2 -14.1696
GIPC2 GIPC PDZ domain containing family, member 2 -8.58568
TANGO6 transport and golgi organization 6 homolog (Drosophila) -8.46397
TLL2 tolloid-like 2 -8.24604
G0S2 G0/G1 switch 2 -5.82375
MMP10 matrix metallopeptidase 10 -4.4568
AKAP12 A kinase (PRKA) anchor protein 12 -4.15478
FNDC3A fibronectin type III domain containing 3A -3.82984
INHBA inhibin, beta A -3.80852
EI24 etoposide induced 2.4 -3.07841
IGSF3 immunoglobulin superfamily, member 3 -2.69718
TMEM64 transmembrane protein 64 -2.69718
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -2.46474
KRT14 keratin 14, type I -2.46474
PARP1 poly (ADP-ribose) polymerase 1 -2.42471
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.39098
MYEOV myeloma overexpressed -2.12318
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -1.88413
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -1.83727
MMP1 matrix metallopeptidase 1 -1.83698
CTSS cathepsin S -1.78639
FBXO33 F-box protein 33 -1.69669
UPP1 uridine phosphorylase 1 -1.52378
BHLHE40 basic helix-loop-helix family, member e40 -1.51116
SSB Sjogren syndrome antigen B (autoantigen La) -1.50168
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) -1.44588
LAMC2 laminin, gamma 2 -1.43467
RABL3 RAB, member of RAS oncogene family-like 3 -1.43467
CDC37L1 cell division cycle 37-like 1 -1.41492
NCOA3 nuclear receptor coactivator 3 -1.40594