| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting PML in Normal Human Dermal Fibroblasts (NHDF) cell (Study accession: SRP221023) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_14102_KD_PML_SRP221023 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 20.0 |
| ASPN | asporin | 20.0 |
| ASPH | aspartate beta-hydroxylase | 20.0 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| MARCH4 | membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase | 20.0 |
| PID1 | phosphotyrosine interaction domain containing 1 | 20.0 |
| P4HA3 | prolyl 4-hydroxylase, alpha polypeptide III | 20.0 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 20.0 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 20.0 |
| HAS2 | hyaluronan synthase 2 | 20.0 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 20.0 |
| BRCA1 | breast cancer 1, early onset | 20.0 |
| KIF23 | kinesin family member 23 | 20.0 |
| INSIG1 | insulin induced gene 1 | 20.0 |
| TPM4 | tropomyosin 4 | 20.0 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 20.0 |
| PERP | PERP, TP53 apoptosis effector | 20.0 |
| ZNF616 | zinc finger protein 616 | 20.0 |
| MKI67 | marker of proliferation Ki-67 | 20.0 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 20.0 |
| DDIT4L | DNA-damage-inducible transcript 4-like | 20.0 |
| FAM180A | family with sequence similarity 180, member A | 20.0 |
| PLCB4 | phospholipase C, beta 4 | 20.0 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 20.0 |
| ARHGAP18 | Rho GTPase activating protein 18 | 20.0 |
| MGLL | monoglyceride lipase | 20.0 |
| PHTF2 | putative homeodomain transcription factor 2 | 20.0 |
| GCK | glucokinase (hexokinase 4) | 20.0 |
| MOSPD2 | motile sperm domain containing 2 | 20.0 |
| DUSP3 | dual specificity phosphatase 3 | 20.0 |
| PDS5B | PDS5 cohesin associated factor B | 20.0 |
| PODXL | podocalyxin-like | 20.0 |
| ANLN | anillin, actin binding protein | 20.0 |
| CDK1 | cyclin-dependent kinase 1 | 20.0 |
| INHBA | inhibin, beta A | 20.0 |
| COL4A1 | collagen, type IV, alpha 1 | 20.0 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 20.0 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 20.0 |
| ANGPT1 | angiopoietin 1 | 20.0 |
| FRMD3 | FERM domain containing 3 | 20.0 |
| BICD2 | bicaudal D homolog 2 (Drosophila) | 20.0 |
| ESM1 | endothelial cell-specific molecule 1 | 20.0 |
| MEDAG | mesenteric estrogen-dependent adipogenesis | 20.0 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 20.0 |
| CDK14 | cyclin-dependent kinase 14 | 20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 20.0 |
| CKAP2 | cytoskeleton associated protein 2 | 20.0 |
| ATAD2 | ATPase family, AAA domain containing 2 | 20.0 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 20.0 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 20.0 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 20.0 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 20.0 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 20.0 |
| MT2A | metallothionein 2A | 20.0 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 20.0 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 20.0 |
| KNTC1 | kinetochore associated 1 | 20.0 |
| ITGA6 | integrin, alpha 6 | 20.0 |
| FHOD3 | formin homology 2 domain containing 3 | 20.0 |
| ZW10 | zw10 kinetochore protein | 20.0 |
| ABLIM3 | actin binding LIM protein family, member 3 | 20.0 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | 20.0 |
| TSPAN13 | tetraspanin 13 | 20.0 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 20.0 |
| RGS4 | regulator of G-protein signaling 4 | 20.0 |
| CTSL | cathepsin L | 20.0 |
| OGFRL1 | opioid growth factor receptor-like 1 | 20.0 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 20.0 |
| RND3 | Rho family GTPase 3 | 20.0 |
| NCAPG | non-SMC condensin I complex, subunit G | 20.0 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 20.0 |
| ANXA1 | annexin A1 | 20.0 |
| IL33 | interleukin 33 | 20.0 |
| CKAP2L | cytoskeleton associated protein 2-like | 20.0 |
| NEFM | neurofilament, medium polypeptide | 20.0 |
| HMGA2 | high mobility group AT-hook 2 | 20.0 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) | 20.0 |
| MYO10 | myosin X | 20.0 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 20.0 |
| CEP170 | centrosomal protein 170kDa | 20.0 |
| BMP2 | bone morphogenetic protein 2 | 20.0 |
| MT1E | metallothionein 1E | 20.0 |
| MMP3 | matrix metallopeptidase 3 | 20.0 |
| MMP1 | matrix metallopeptidase 1 | 20.0 |
| PRKG2 | protein kinase, cGMP-dependent, type II | 20.0 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 20.0 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 20.0 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 20.0 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 19.699 |
| LRRC58 | leucine rich repeat containing 58 | 19.5229 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 19.5229 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 19.5229 |
| CLSPN | claspin | 19.5229 |
| TBX3 | T-box 3 | 19.3979 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 19.301 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 19.2218 |
| THUMPD1 | THUMP domain containing 1 | 19.1549 |
| PPARG | peroxisome proliferator-activated receptor gamma | 19.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CPT1C | carnitine palmitoyltransferase 1C | -20.0 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -20.0 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -20.0 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -20.0 |
| ISG15 | ISG15 ubiquitin-like modifier | -20.0 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | -20.0 |
| STAC | SH3 and cysteine rich domain | -20.0 |
| IRF7 | interferon regulatory factor 7 | -20.0 |
| CXCL16 | chemokine (C-X-C motif) ligand 16 | -20.0 |
| MEX3B | mex-3 RNA binding family member B | -20.0 |
| NEO1 | neogenin 1 | -20.0 |
| TMEM14B | transmembrane protein 14B | -20.0 |
| TMEM14C | transmembrane protein 14C | -20.0 |
| RNF167 | ring finger protein 167 | -20.0 |
| DHX58 | DEXH (Asp-Glu-X-His) box polypeptide 58 | -20.0 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -20.0 |
| IFITM1 | interferon induced transmembrane protein 1 | -20.0 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -20.0 |
| TRO | trophinin | -20.0 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | -20.0 |
| PKDCC | protein kinase domain containing, cytoplasmic | -20.0 |
| RCOR1 | REST corepressor 1 | -20.0 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | -20.0 |
| CYB561 | cytochrome b561 | -20.0 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -20.0 |
| LOC728392 | uncharacterized LOC728392 | -20.0 |
| LAMA5 | laminin, alpha 5 | -20.0 |
| BAALC | brain and acute leukemia, cytoplasmic | -20.0 |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 | -20.0 |
| BST2 | bone marrow stromal cell antigen 2 | -20.0 |
| EMILIN2 | elastin microfibril interfacer 2 | -20.0 |
| COMMD9 | COMM domain containing 9 | -20.0 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | -20.0 |
| AKNA | AT-hook transcription factor | -20.0 |
| GPX7 | glutathione peroxidase 7 | -20.0 |
| SYT11 | synaptotagmin XI | -20.0 |
| PTK2B | protein tyrosine kinase 2 beta | -20.0 |
| GDF5 | growth differentiation factor 5 | -20.0 |
| FAM171A1 | family with sequence similarity 171, member A1 | -20.0 |
| BRSK1 | BR serine/threonine kinase 1 | -20.0 |
| A2M | alpha-2-macroglobulin | -20.0 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -20.0 |
| ADGRB2 | adhesion G protein-coupled receptor B2 | -20.0 |
| MRVI1 | murine retrovirus integration site 1 homolog | -20.0 |
| SBSN | suprabasin | -20.0 |
| C3 | complement component 3 | -20.0 |
| SOCS2 | suppressor of cytokine signaling 2 | -20.0 |
| MOCOS | molybdenum cofactor sulfurase | -20.0 |
| SLC7A14 | solute carrier family 7, member 14 | -20.0 |
| ITGA7 | integrin, alpha 7 | -20.0 |
| EGR3 | early growth response 3 | -20.0 |
| LMOD1 | leiomodin 1 (smooth muscle) | -20.0 |
| DAB1 | Dab, reelin signal transducer, homolog 1 (Drosophila) | -20.0 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -20.0 |
| PARD3 | par-3 family cell polarity regulator | -20.0 |
| SARM1 | sterile alpha and TIR motif containing 1 | -20.0 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 | -20.0 |
| C11ORF96 | chromosome 11 open reading frame 96 | -20.0 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -20.0 |
| SV2A | synaptic vesicle glycoprotein 2A | -20.0 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -20.0 |
| CPXM1 | carboxypeptidase X (M14 family), member 1 | -20.0 |
| TYMP | thymidine phosphorylase | -20.0 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | -20.0 |
| CHMP3 | charged multivesicular body protein 3 | -20.0 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -20.0 |
| ADRA2A | adrenoceptor alpha 2A | -20.0 |
| KRTAP1-5 | keratin associated protein 1-5 | -20.0 |
| UNC5B | unc-5 homolog B (C. elegans) | -20.0 |
| CEND1 | cell cycle exit and neuronal differentiation 1 | -20.0 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 | -20.0 |
| TSPAN11 | tetraspanin 11 | -20.0 |
| IFI35 | interferon-induced protein 35 | -20.0 |
| SAMHD1 | SAM domain and HD domain 1 | -20.0 |
| FZD4 | frizzled class receptor 4 | -20.0 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -20.0 |
| PBX2 | pre-B-cell leukemia homeobox 2 | -20.0 |
| MX2 | MX dynamin-like GTPase 2 | -20.0 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -20.0 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 | -20.0 |
| MYD88 | myeloid differentiation primary response 88 | -20.0 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -20.0 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -20.0 |
| KREMEN1 | kringle containing transmembrane protein 1 | -20.0 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 | -20.0 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -20.0 |
| IFI27 | interferon, alpha-inducible protein 27 | -20.0 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -20.0 |
| TLCD2 | TLC domain containing 2 | -20.0 |
| PPL | periplakin | -20.0 |
| ACAN | aggrecan | -20.0 |
| MEST | mesoderm specific transcript | -20.0 |
| C10ORF10 | chromosome 10 open reading frame 10 | -20.0 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -20.0 |
| SELENBP1 | selenium binding protein 1 | -20.0 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin | -20.0 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -20.0 |
| IRX3 | iroquois homeobox 3 | -20.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | -20.0 |
