| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting FOXM1 in OPM2 human myeloma cell line cell line (Study accession: SRP328179) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_14246_KO_FOXM1_SRP328179 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 20.0 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 20.0 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 20.0 |
| RCSD1 | RCSD domain containing 1 | 20.0 |
| MCM4 | minichromosome maintenance complex component 4 | 20.0 |
| SCARB1 | scavenger receptor class B, member 1 | 20.0 |
| HES6 | hes family bHLH transcription factor 6 | 20.0 |
| MYRF | myelin regulatory factor | 20.0 |
| PDIA2 | protein disulfide isomerase family A, member 2 | 20.0 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 20.0 |
| CD276 | CD276 molecule | 20.0 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 20.0 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 20.0 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 20.0 |
| CCDC86 | coiled-coil domain containing 86 | 20.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | 20.0 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 20.0 |
| EPHB2 | EPH receptor B2 | 20.0 |
| NBEAL2 | neurobeachin-like 2 | 20.0 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 20.0 |
| ZNF692 | zinc finger protein 692 | 20.0 |
| TFRC | transferrin receptor | 20.0 |
| WDR90 | WD repeat domain 90 | 20.0 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 20.0 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 20.0 |
| JAG2 | jagged 2 | 20.0 |
| BEST3 | bestrophin 3 | 20.0 |
| TNPO2 | transportin 2 | 20.0 |
| MYO18A | myosin XVIIIA | 20.0 |
| LAMA5 | laminin, alpha 5 | 20.0 |
| ABR | active BCR-related | 20.0 |
| CSK | c-src tyrosine kinase | 20.0 |
| GOLM1 | golgi membrane protein 1 | 20.0 |
| HSPA8 | heat shock 70kDa protein 8 | 20.0 |
| HIP1R | huntingtin interacting protein 1 related | 20.0 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 20.0 |
| RAI14 | retinoic acid induced 14 | 20.0 |
| TRIP10 | thyroid hormone receptor interactor 10 | 20.0 |
| ZNF121 | zinc finger protein 121 | 20.0 |
| MEGF6 | multiple EGF-like-domains 6 | 20.0 |
| SEPT3 | septin 3 | 20.0 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 20.0 |
| CD44 | CD44 molecule (Indian blood group) | 20.0 |
| SACS | sacsin molecular chaperone | 20.0 |
| RERG | RAS-like, estrogen-regulated, growth inhibitor | 20.0 |
| GSE1 | Gse1 coiled-coil protein | 20.0 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 20.0 |
| PODXL | podocalyxin-like | 20.0 |
| TAGLN2 | transgelin 2 | 20.0 |
| FKBP4 | FK506 binding protein 4, 59kDa | 20.0 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 20.0 |
| INF2 | inverted formin, FH2 and WH2 domain containing | 20.0 |
| MYADM | myeloid-associated differentiation marker | 20.0 |
| KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 | 20.0 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 20.0 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 20.0 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 20.0 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | 20.0 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 20.0 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 20.0 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 20.0 |
| ITGB7 | integrin, beta 7 | 20.0 |
| TPCN1 | two pore segment channel 1 | 20.0 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) | 20.0 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 20.0 |
| FHOD1 | formin homology 2 domain containing 1 | 20.0 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 20.0 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 20.0 |
| ADAM15 | ADAM metallopeptidase domain 15 | 20.0 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 20.0 |
| SDCCAG3 | serologically defined colon cancer antigen 3 | 20.0 |
| PAGE5 | P antigen family, member 5 (prostate associated) | 20.0 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 20.0 |
| VAV1 | vav 1 guanine nucleotide exchange factor | 20.0 |
| ARHGAP21 | Rho GTPase activating protein 21 | 20.0 |
| IL4R | interleukin 4 receptor | 20.0 |
| ANXA4 | annexin A4 | 20.0 |
| PUS7 | pseudouridylate synthase 7 (putative) | 20.0 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 20.0 |
| MED9 | mediator complex subunit 9 | 20.0 |
| MNX1 | motor neuron and pancreas homeobox 1 | 20.0 |
| PRDX2 | peroxiredoxin 2 | 20.0 |
| KAT2A | K(lysine) acetyltransferase 2A | 20.0 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 20.0 |
| NCS1 | neuronal calcium sensor 1 | 20.0 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 20.0 |
| ADAM23 | ADAM metallopeptidase domain 23 | 20.0 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 20.0 |
| CD81 | CD81 molecule | 20.0 |
| SLC25A53 | solute carrier family 25, member 53 | 20.0 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 20.0 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 20.0 |
| ENDOD1 | endonuclease domain containing 1 | 20.0 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 20.0 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 20.0 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor | 20.0 |
| NOP56 | NOP56 ribonucleoprotein | 20.0 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 20.0 |
| TFDP1 | transcription factor Dp-1 | 20.0 |
| SUGP2 | SURP and G patch domain containing 2 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RHOH | ras homolog family member H | -20.0 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -20.0 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -20.0 |
| TJP1 | tight junction protein 1 | -20.0 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | -20.0 |
| SNAP29 | synaptosomal-associated protein, 29kDa | -20.0 |
| DENND5B | DENN/MADD domain containing 5B | -20.0 |
| MEI1 | meiosis inhibitor 1 | -20.0 |
| PLCH1 | phospholipase C, eta 1 | -20.0 |
| CCL3 | chemokine (C-C motif) ligand 3 | -20.0 |
| GSTM1 | glutathione S-transferase mu 1 | -20.0 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | -20.0 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 | -20.0 |
| MAGED1 | melanoma antigen family D1 | -20.0 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | -20.0 |
| HRK | harakiri, BCL2 interacting protein | -20.0 |
| TXNDC15 | thioredoxin domain containing 15 | -20.0 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -20.0 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -20.0 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -20.0 |
| DPYSL2 | dihydropyrimidinase-like 2 | -20.0 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -20.0 |
| STX5 | syntaxin 5 | -20.0 |
| TMEM143 | transmembrane protein 143 | -20.0 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -20.0 |
| PLXDC2 | plexin domain containing 2 | -20.0 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | -20.0 |
| FRY | furry homolog (Drosophila) | -20.0 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -20.0 |
| PYROXD2 | pyridine nucleotide-disulphide oxidoreductase domain 2 | -20.0 |
| TRIOBP | TRIO and F-actin binding protein | -20.0 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -20.0 |
| SELL | selectin L | -20.0 |
| RAB30 | RAB30, member RAS oncogene family | -20.0 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -20.0 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -20.0 |
| FANCF | Fanconi anemia, complementation group F | -20.0 |
| ACP2 | acid phosphatase 2, lysosomal | -20.0 |
| ARHGAP9 | Rho GTPase activating protein 9 | -20.0 |
| CYTIP | cytohesin 1 interacting protein | -20.0 |
| H1FX | H1 histone family, member X | -20.0 |
| FAM167A | family with sequence similarity 167, member A | -20.0 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -20.0 |
| MBNL2 | muscleblind-like splicing regulator 2 | -20.0 |
| MLH1 | mutL homolog 1 | -20.0 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -20.0 |
| WSCD1 | WSC domain containing 1 | -20.0 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | -20.0 |
| CTH | cystathionine gamma-lyase | -20.0 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -20.0 |
| ITGA8 | integrin, alpha 8 | -20.0 |
| FBXO40 | F-box protein 40 | -20.0 |
| EMP3 | epithelial membrane protein 3 | -20.0 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -20.0 |
| TROAP | trophinin associated protein | -20.0 |
| ACVR1 | activin A receptor, type I | -20.0 |
| NMRAL1 | NmrA-like family domain containing 1 | -20.0 |
| IL21R | interleukin 21 receptor | -20.0 |
| PHF21A | PHD finger protein 21A | -20.0 |
| ADNP2 | ADNP homeobox 2 | -20.0 |
| RGS16 | regulator of G-protein signaling 16 | -20.0 |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 | -20.0 |
| SMIM14 | small integral membrane protein 14 | -20.0 |
| NDE1 | nudE neurodevelopment protein 1 | -20.0 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | -20.0 |
| DDIT3 | DNA-damage-inducible transcript 3 | -20.0 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | -20.0 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -20.0 |
| SLC35F1 | solute carrier family 35, member F1 | -20.0 |
| TUBA1A | tubulin, alpha 1a | -20.0 |
| DCC | DCC netrin 1 receptor | -20.0 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 | -20.0 |
| LY9 | lymphocyte antigen 9 | -20.0 |
| RHBDD2 | rhomboid domain containing 2 | -20.0 |
| GTSE1 | G-2 and S-phase expressed 1 | -20.0 |
| ARHGAP28 | Rho GTPase activating protein 28 | -20.0 |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | -20.0 |
| DSEL | dermatan sulfate epimerase-like | -20.0 |
| IL10RA | interleukin 10 receptor, alpha | -20.0 |
| OTOGL | otogelin-like | -20.0 |
| SHISA3 | shisa family member 3 | -20.0 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -20.0 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -20.0 |
| NLRP11 | NLR family, pyrin domain containing 11 | -20.0 |
| AMPD3 | adenosine monophosphate deaminase 3 | -20.0 |
| AMPD1 | adenosine monophosphate deaminase 1 | -20.0 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -20.0 |
| NEURL1B | neuralized E3 ubiquitin protein ligase 1B | -20.0 |
| SCPEP1 | serine carboxypeptidase 1 | -20.0 |
| SULF1 | sulfatase 1 | -20.0 |
| HLTF | helicase-like transcription factor | -20.0 |
| FICD | FIC domain containing | -20.0 |
| STBD1 | starch binding domain 1 | -20.0 |
| CLEC7A | C-type lectin domain family 7, member A | -20.0 |
| MRPS21 | mitochondrial ribosomal protein S21 | -20.0 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -20.0 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -20.0 |
| SH2D3C | SH2 domain containing 3C | -20.0 |
| HMP19 | HMP19 protein | -20.0 |
| GALC | galactosylceramidase | -20.0 |