| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CYTOR in Oral cancer cell cell line (Study accession: SRP353785) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_14249_KD_CYTOR_SRP353785 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DOC2B | double C2-like domains, beta | 20.0 |
| H1F0 | H1 histone family, member 0 | 20.0 |
| GDF15 | growth differentiation factor 15 | 20.0 |
| BTF3L4 | basic transcription factor 3-like 4 | 20.0 |
| IFI44L | interferon-induced protein 44-like | 20.0 |
| NGFR | nerve growth factor receptor | 20.0 |
| AGR2 | anterior gradient 2 | 20.0 |
| PADI3 | peptidyl arginine deiminase, type III | 20.0 |
| IL20RB | interleukin 20 receptor beta | 19.699 |
| PGLYRP4 | peptidoglycan recognition protein 4 | 19.301 |
| LOXL4 | lysyl oxidase-like 4 | 19.301 |
| HTRA1 | HtrA serine peptidase 1 | 17.9031 |
| TMPRSS4 | transmembrane protease, serine 4 | 17.2503 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 15.6229 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 15.6105 |
| CALB1 | calbindin 1, 28kDa | 15.4502 |
| TRIB3 | tribbles pseudokinase 3 | 15.4392 |
| GLUL | glutamate-ammonia ligase | 14.9593 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 14.8705 |
| RCAN1 | regulator of calcineurin 1 | 14.8657 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 14.6552 |
| NEURL1B | neuralized E3 ubiquitin protein ligase 1B | 14.6552 |
| EREG | epiregulin | 14.5006 |
| RGS3 | regulator of G-protein signaling 3 | 14.4946 |
| TSC22D3 | TSC22 domain family, member 3 | 14.3424 |
| IFI27 | interferon, alpha-inducible protein 27 | 13.3676 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 13.2173 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 12.5637 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 12.55 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 12.4523 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 | 12.3891 |
| KIF21B | kinesin family member 21B | 12.0611 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 11.727 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 11.5965 |
| ADM2 | adrenomedullin 2 | 11.1509 |
| KNDC1 | kinase non-catalytic C-lobe domain (KIND) containing 1 | 11.0978 |
| ARRDC4 | arrestin domain containing 4 | 10.6269 |
| MMP1 | matrix metallopeptidase 1 | 10.5112 |
| PSAT1 | phosphoserine aminotransferase 1 | 10.4425 |
| AREG | amphiregulin | 10.2446 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 10.2431 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 10.1586 |
| ASS1 | argininosuccinate synthase 1 | 10.1586 |
| TLCD2 | TLC domain containing 2 | 10.0833 |
| CCND2 | cyclin D2 | 9.77699 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 9.5561 |
| WASL | Wiskott-Aldrich syndrome-like | 9.55064 |
| MX2 | MX dynamin-like GTPase 2 | 9.45451 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 9.45451 |
| IFI6 | interferon, alpha-inducible protein 6 | 9.45451 |
| TBL1X | transducin (beta)-like 1X-linked | 9.40188 |
| XBP1 | X-box binding protein 1 | 9.15467 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 9.15293 |
| MXI1 | MAX interactor 1, dimerization protein | 9.02138 |
| WNT3A | wingless-type MMTV integration site family, member 3A | 8.9417 |
| GPNMB | glycoprotein (transmembrane) nmb | 8.91914 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 8.75665 |
| SLFN5 | schlafen family member 5 | 8.71376 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 8.53965 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 8.5349 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 8.42815 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 8.42226 |
| S100A7A | S100 calcium binding protein A7A | 8.28958 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 8.2449 |
| MZT1 | mitotic spindle organizing protein 1 | 8.2449 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 8.24216 |
| HID1 | HID1 domain containing | 8.23154 |
| SAMD9 | sterile alpha motif domain containing 9 | 8.22995 |
| PDE9A | phosphodiesterase 9A | 8.20002 |
| TP53I11 | tumor protein p53 inducible protein 11 | 8.17692 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 7.90374 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 7.88294 |
| GJB6 | gap junction protein, beta 6, 30kDa | 7.87504 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 7.832 |
| DDIT3 | DNA-damage-inducible transcript 3 | 7.68352 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 | 7.66441 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 7.62154 |
| MLXIPL | MLX interacting protein-like | 7.56237 |
| LAMP3 | lysosomal-associated membrane protein 3 | 7.56237 |
| AQP3 | aquaporin 3 (Gill blood group) | 7.52909 |
| TOX2 | TOX high mobility group box family member 2 | 7.52909 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 7.523 |
| SORT1 | sortilin 1 | 7.48571 |
| ESRP1 | epithelial splicing regulatory protein 1 | 7.44527 |
| IL17C | interleukin 17C | 7.37555 |
| IL1RN | interleukin 1 receptor antagonist | 7.2963 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A | 7.28796 |
| ATP9A | ATPase, class II, type 9A | 7.25393 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 7.24421 |
| CORO2A | coronin, actin binding protein, 2A | 7.24421 |
| WARS | tryptophanyl-tRNA synthetase | 7.15716 |
| ARTN | artemin | 7.13896 |
| PIGR | polymeric immunoglobulin receptor | 7.01536 |
| SH3RF3 | SH3 domain containing ring finger 3 | 7.01242 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 6.99523 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 6.9777 |
| PADI2 | peptidyl arginine deiminase, type II | 6.96156 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 6.95624 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 6.88975 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 6.88151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPIF | peptidylprolyl isomerase F | -20.0 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | -20.0 |
| MYH16 | myosin, heavy chain 16 pseudogene | -15.9708 |
| IL1R2 | interleukin 1 receptor, type II | -14.1752 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | -13.7526 |
| ARL4C | ADP-ribosylation factor-like 4C | -12.8602 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) | -12.7524 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -12.2717 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -12.0272 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -11.8618 |
| BYSL | bystin-like | -10.4867 |
| TUBB4B | tubulin, beta 4B class IVb | -9.51195 |
| CPA4 | carboxypeptidase A4 | -9.40082 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -9.04428 |
| WNT7A | wingless-type MMTV integration site family, member 7A | -9.03 |
| CTGF | connective tissue growth factor | -8.95669 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | -8.89706 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -8.67731 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 | -8.39611 |
| SPHK1 | sphingosine kinase 1 | -8.31984 |
| RRAD | Ras-related associated with diabetes | -8.23528 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -8.08697 |
| CCNA2 | cyclin A2 | -7.66717 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -7.53693 |
| NOL6 | nucleolar protein 6 (RNA-associated) | -7.52909 |
| NKX1-2 | NK1 homeobox 2 | -7.48571 |
| ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | -7.31572 |
| HSPA8 | heat shock 70kDa protein 8 | -6.91597 |
| VCP | valosin containing protein | -6.89088 |
| IFFO2 | intermediate filament family orphan 2 | -6.8461 |
| PLK1 | polo-like kinase 1 | -6.63515 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -6.56801 |
| ELAC2 | elaC ribonuclease Z 2 | -6.45112 |
| PGAM5 | phosphoglycerate mutase family member 5 | -6.34902 |
| ODC1 | ornithine decarboxylase 1 | -6.31092 |
| BRICD5 | BRICHOS domain containing 5 | -6.29208 |
| CORO6 | coronin 6 | -6.233 |
| HCFC1 | host cell factor C1 | -6.09879 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -6.08675 |
| TMEM109 | transmembrane protein 109 | -6.08338 |
| ACTB | actin, beta | -6.0017 |
| GPATCH4 | G patch domain containing 4 | -5.92138 |
| HSPA1A | heat shock 70kDa protein 1A | -5.7611 |
| DOK3 | docking protein 3 | -5.74273 |
| ATAD3B | ATPase family, AAA domain containing 3B | -5.74273 |
| HSPE1 | heat shock 10kDa protein 1 | -5.73 |
| TMEM97 | transmembrane protein 97 | -5.65463 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -5.61841 |
| SAFB | scaffold attachment factor B | -5.58569 |
| FJX1 | four jointed box 1 (Drosophila) | -5.54182 |
| ZNF574 | zinc finger protein 574 | -5.50105 |
| AEN | apoptosis enhancing nuclease | -5.47837 |
| SRRT | serrate, RNA effector molecule | -5.36745 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -5.36608 |
| PTDSS1 | phosphatidylserine synthase 1 | -5.34995 |
| CARD10 | caspase recruitment domain family, member 10 | -5.34302 |
| ZNF488 | zinc finger protein 488 | -5.26155 |
| ORC1 | origin recognition complex, subunit 1 | -5.24315 |
| SCRIB | scribbled planar cell polarity protein | -5.23885 |
| MLKL | mixed lineage kinase domain-like | -5.21953 |
| CD3EAP | CD3e molecule, epsilon associated protein | -5.21953 |
| FHOD1 | formin homology 2 domain containing 1 | -5.19079 |
| DHX37 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | -5.14188 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) | -5.12574 |
| MCRS1 | microspherule protein 1 | -5.09439 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | -5.03006 |
| C9ORF69 | chromosome 9 open reading frame 69 | -5.01638 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -4.97431 |
| GRPEL1 | GrpE-like 1, mitochondrial (E. coli) | -4.95442 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -4.92344 |
| RBM19 | RNA binding motif protein 19 | -4.86394 |
| FEM1A | fem-1 homolog a (C. elegans) | -4.85682 |
| SRRM2 | serine/arginine repetitive matrix 2 | -4.85516 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -4.8286 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.82594 |
| CMTM4 | CKLF-like MARVEL transmembrane domain containing 4 | -4.82395 |
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) | -4.81051 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -4.77253 |
| TRIM16 | tripartite motif containing 16 | -4.76243 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | -4.73753 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -4.70455 |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | -4.70016 |
| VAMP3 | vesicle-associated membrane protein 3 | -4.65429 |
| FAM57A | family with sequence similarity 57, member A | -4.6237 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | -4.61733 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | -4.6017 |
| GLA | galactosidase, alpha | -4.5174 |
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | -4.50638 |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) | -4.46741 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) | -4.461 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | -4.46055 |
| FERMT3 | fermitin family member 3 | -4.44943 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -4.41737 |
| MCM5 | minichromosome maintenance complex component 5 | -4.41184 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | -4.40332 |
| HSPB8 | heat shock 22kDa protein 8 | -4.39721 |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | -4.3766 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) | -4.34822 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | -4.34724 |
| KTI12 | KTI12 homolog, chromatin associated (S. cerevisiae) | -4.33556 |
