| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting H14 in PLB-985 cell line (Study accession: ERP118037) (PerturbAtlas) |
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106 genes differentially expressed following the Perturb_14878_KO_H14_ERP118037 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MKS1 | Meckel syndrome, type 1 | 20.0 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 15.5105 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 11.2571 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | 9.68491 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 9.01557 |
| FAM131A | family with sequence similarity 131, member A | 4.97704 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 4.75032 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 4.53132 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 | 4.51978 |
| CDC14B | cell division cycle 14B | 3.69889 |
| FSIP1 | fibrous sheath interacting protein 1 | 3.61275 |
| CISD3 | CDGSH iron sulfur domain 3 | 3.60269 |
| SPDYE3 | speedy/RINGO cell cycle regulator family member E3 | 3.38713 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | 3.20993 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | 3.13636 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | 2.74114 |
| TMEM160 | transmembrane protein 160 | 2.68388 |
| CERKL | ceramide kinase-like | 2.68388 |
| RHOF | ras homolog family member F (in filopodia) | 2.54881 |
| AHNAK2 | AHNAK nucleoprotein 2 | 2.53532 |
| GPR162 | G protein-coupled receptor 162 | 2.50679 |
| FCHSD1 | FCH and double SH3 domains 1 | 2.4703 |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) | 2.4703 |
| PLLP | plasmolipin | 2.20298 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | 2.20298 |
| IL17D | interleukin 17D | 2.19557 |
| EPX | eosinophil peroxidase | 2.0095 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 2.00235 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 1.98507 |
| GATA2 | GATA binding protein 2 | 1.93896 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | 1.93025 |
| PRR29 | proline rich 29 | 1.92762 |
| C16ORF93 | chromosome 16 open reading frame 93 | 1.90396 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 1.89134 |
| C1ORF74 | chromosome 1 open reading frame 74 | 1.83223 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 1.80579 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 1.7927 |
| RELL2 | RELT-like 2 | 1.7767 |
| ACTR1A | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) | 1.75718 |
| MMEL1 | membrane metallo-endopeptidase-like 1 | 1.70237 |
| AVPR2 | arginine vasopressin receptor 2 | 1.69499 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 1.53037 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | 1.49063 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | 1.36155 |
| AHNAK | AHNAK nucleoprotein | 1.35608 |
| ERICH6B | glutamate-rich 6B | 1.3531 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 1.34507 |
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 1.32759 |
| VASH1 | vasohibin 1 | 1.30974 |
| TRIM24 | tripartite motif containing 24 | 1.30568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MPO | myeloperoxidase | -12.313 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -9.0158 |
| LPO | lactoperoxidase | -7.90118 |
| PANK2 | pantothenate kinase 2 | -7.84386 |
| MTBP | MDM2 binding protein | -7.84386 |
| BRICD5 | BRICHOS domain containing 5 | -7.00913 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -6.79119 |
| RELL1 | RELT-like 1 | -6.05596 |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 | -4.90178 |
| OGG1 | 8-oxoguanine DNA glycosylase | -4.0976 |
| LIPM | lipase, family member M | -3.8608 |
| PAQR4 | progestin and adipoQ receptor family member IV | -3.39553 |
| PMM2 | phosphomannomutase 2 | -3.37204 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -3.33888 |
| BAIAP3 | BAI1-associated protein 3 | -3.2709 |
| PRTN3 | proteinase 3 | -3.13636 |
| PCNXL4 | pecanex-like 4 (Drosophila) | -3.12257 |
| EME2 | essential meiotic structure-specific endonuclease subunit 2 | -3.07718 |
| GCDH | glutaryl-CoA dehydrogenase | -2.87847 |
| KIAA1257 | KIAA1257 | -2.85441 |
| THOC6 | THO complex 6 | -2.7085 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.69244 |
| SLC45A4 | solute carrier family 45, member 4 | -2.66073 |
| MCM2 | minichromosome maintenance complex component 2 | -2.63787 |
| PRR33 | proline rich 33 | -2.60276 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | -2.51974 |
| ZNF263 | zinc finger protein 263 | -2.36647 |
| C1ORF228 | chromosome 1 open reading frame 228 | -2.36149 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.29495 |
| DNASE1 | deoxyribonuclease I | -2.26637 |
| ALG1 | ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase | -2.25731 |
| CCNA2 | cyclin A2 | -2.02654 |
| MGAM | maltase-glucoamylase | -2.00235 |
| ARMC5 | armadillo repeat containing 5 | -1.90558 |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) | -1.90558 |
| EIF4E3 | eukaryotic translation initiation factor 4E family member 3 | -1.83223 |
| COMMD5 | COMM domain containing 5 | -1.83223 |
| NF1 | neurofibromin 1 | -1.72113 |
| FKRP | fukutin related protein | -1.69499 |
| FKBP15 | FK506 binding protein 15, 133kDa | -1.6694 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -1.62564 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -1.60618 |
| MPG | N-methylpurine-DNA glycosylase | -1.57865 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | -1.55715 |
| CTBP1 | C-terminal binding protein 1 | -1.5546 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -1.55228 |
| MPRIP | myosin phosphatase Rho interacting protein | -1.53726 |
| TMPO | thymopoietin | -1.49756 |
| C12ORF45 | chromosome 12 open reading frame 45 | -1.48427 |
| TMEM120B | transmembrane protein 120B | -1.40428 |
| WDR24 | WD repeat domain 24 | -1.39852 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -1.39852 |
| MYL5 | myosin, light chain 5, regulatory | -1.37593 |
| FAM195A | family with sequence similarity 195, member A | -1.34027 |
| MRPS18C | mitochondrial ribosomal protein S18C | -1.32684 |
| PRIMPOL | primase and polymerase (DNA-directed) | -1.30544 |
