| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting H11 in PLB-985 cell line (Study accession: ERP118037) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_14882_KO_H11_ERP118037 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR33 | proline rich 33 | 20.0 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 | 15.5533 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 | 12.4211 |
| OGG1 | 8-oxoguanine DNA glycosylase | 10.5767 |
| DTX1 | deltex 1, E3 ubiquitin ligase | 9.63167 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 8.6711 |
| TSPAN3 | tetraspanin 3 | 8.46348 |
| MARS | methionyl-tRNA synthetase | 8.39144 |
| RAB43 | RAB43, member RAS oncogene family | 8.19573 |
| BOP1 | block of proliferation 1 | 7.73056 |
| GNPTG | N-acetylglucosamine-1-phosphate transferase, gamma subunit | 7.6408 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 7.48981 |
| BEST1 | bestrophin 1 | 7.15638 |
| RPL10 | ribosomal protein L10 | 7.08458 |
| MAPK10 | mitogen-activated protein kinase 10 | 6.89685 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 6.79212 |
| DNAH10 | dynein, axonemal, heavy chain 10 | 6.70764 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | 6.60407 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 6.34453 |
| B9D1 | B9 protein domain 1 | 6.24561 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 6.18464 |
| ZNF497 | zinc finger protein 497 | 5.95315 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 5.77884 |
| MGST2 | microsomal glutathione S-transferase 2 | 5.73483 |
| PPM1N | protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) | 5.51877 |
| ARHGAP9 | Rho GTPase activating protein 9 | 5.36684 |
| UBXN11 | UBX domain protein 11 | 5.36684 |
| CSNK1D | casein kinase 1, delta | 4.95902 |
| PDAP1 | PDGFA associated protein 1 | 4.94861 |
| PFDN6 | prefoldin subunit 6 | 4.83225 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) | 4.81252 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | 4.78275 |
| NIPAL1 | NIPA-like domain containing 1 | 4.58411 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 4.55253 |
| HOOK2 | hook microtubule-tethering protein 2 | 4.54171 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | 4.50387 |
| EPHA1 | EPH receptor A1 | 4.44967 |
| TCTN1 | tectonic family member 1 | 4.41263 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | 4.36588 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 | 4.28369 |
| MPI | mannose phosphate isomerase | 4.27457 |
| STAG3 | stromal antigen 3 | 4.27457 |
| ANGPTL6 | angiopoietin-like 6 | 4.25261 |
| UNC5A | unc-5 homolog A (C. elegans) | 4.24716 |
| RAB37 | RAB37, member RAS oncogene family | 4.14022 |
| C5ORF45 | chromosome 5 open reading frame 45 | 4.12851 |
| FOXH1 | forkhead box H1 | 4.10356 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 4.03247 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | 4.00892 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 3.99344 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 3.95181 |
| OPRM1 | opioid receptor, mu 1 | 3.92916 |
| ZACN | zinc activated ligand-gated ion channel | 3.92621 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 3.87467 |
| HIST1H4I | histone cluster 1, H4i | 3.78748 |
| LINC00514 | long intergenic non-protein coding RNA 514 | 3.78748 |
| IGSF6 | immunoglobulin superfamily, member 6 | 3.78173 |
| NF1 | neurofibromin 1 | 3.72397 |
| SH3D21 | SH3 domain containing 21 | 3.71557 |
| PRKCZ | protein kinase C, zeta | 3.70655 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 3.70366 |
| ART4 | ADP-ribosyltransferase 4 (Dombrock blood group) | 3.66163 |
| ZNF804A | zinc finger protein 804A | 3.66142 |
| CORO1B | coronin, actin binding protein, 1B | 3.64195 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 3.63568 |
| EME2 | essential meiotic structure-specific endonuclease subunit 2 | 3.59421 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa | 3.58823 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | 3.49811 |
| JMJD8 | jumonji domain containing 8 | 3.48732 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | 3.38206 |
| FANCA | Fanconi anemia, complementation group A | 3.29966 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 3.26507 |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 | 3.18853 |
| DUS2 | dihydrouridine synthase 2 | 3.10127 |
| BRI3 | brain protein I3 | 3.05559 |
| TMEM186 | transmembrane protein 186 | 3.04712 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 3.02324 |
| COG5 | component of oligomeric golgi complex 5 | 2.96086 |
| GCC1 | GRIP and coiled-coil domain containing 1 | 2.94156 |
| CEMP1 | cementum protein 1 | 2.90163 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.84394 |
| PARP10 | poly (ADP-ribose) polymerase family, member 10 | 2.84004 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 2.80006 |
| PTOV1 | prostate tumor overexpressed 1 | 2.77107 |
| CLU | clusterin | 2.7278 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 2.69762 |
| IDUA | iduronidase, alpha-L- | 2.65928 |
| TMEM132A | transmembrane protein 132A | 2.60752 |
| LINGO3 | leucine rich repeat and Ig domain containing 3 | 2.58161 |
| COG7 | component of oligomeric golgi complex 7 | 2.57526 |
| USP34 | ubiquitin specific peptidase 34 | 2.56035 |
| ZNF784 | zinc finger protein 784 | 2.5463 |
| TSC2 | tuberous sclerosis 2 | 2.52989 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 2.51109 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.50975 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | 2.49949 |
| C1ORF56 | chromosome 1 open reading frame 56 | 2.40483 |
| FAM184B | family with sequence similarity 184, member B | 2.40153 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 2.3843 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 2.37599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFT20 | intraflagellar transport 20 | -10.4932 |
| TP53BP1 | tumor protein p53 binding protein 1 | -10.1491 |
| RELL2 | RELT-like 2 | -8.58797 |
| TCP1 | t-complex 1 | -8.58004 |
| LSMEM2 | leucine-rich single-pass membrane protein 2 | -8.37383 |
| IL17D | interleukin 17D | -7.93309 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | -7.61055 |
| CERKL | ceramide kinase-like | -6.73539 |
| MTIF3 | mitochondrial translational initiation factor 3 | -6.66429 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -6.26446 |
| PMEL | premelanosome protein | -5.59848 |
| DIS3L | DIS3 like exosome 3'-5' exoribonuclease | -5.55459 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | -5.36684 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -5.36515 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | -5.32642 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | -5.30477 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -5.26586 |
| LOC122455342 | testis-specific serine/proline-rich protein | -5.18042 |
| CALR | calreticulin | -5.17152 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | -5.08368 |
| BMP6 | bone morphogenetic protein 6 | -4.93542 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | -4.92065 |
| BBS2 | Bardet-Biedl syndrome 2 | -4.83225 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -4.82101 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | -4.75444 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -4.71943 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 | -4.68425 |
| RNF214 | ring finger protein 214 | -4.52132 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -4.45343 |
| ERCC1 | excision repair cross-complementation group 1 | -4.4275 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | -4.14022 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -4.10356 |
| KLC1 | kinesin light chain 1 | -4.10356 |
| RHOF | ras homolog family member F (in filopodia) | -3.98133 |
| SRR | serine racemase | -3.84455 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -3.7729 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -3.72984 |
| INTS8 | integrator complex subunit 8 | -3.71557 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -3.60938 |
| ADAM17 | ADAM metallopeptidase domain 17 | -3.56684 |
| PLCE1 | phospholipase C, epsilon 1 | -3.55123 |
| DOPEY1 | dopey family member 1 | -3.46062 |
| CLVS1 | clavesin 1 | -3.42 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -3.38206 |
| SPAG17 | sperm associated antigen 17 | -3.3773 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | -3.32306 |
| ZFHX3 | zinc finger homeobox 3 | -3.31219 |
| ZNF771 | zinc finger protein 771 | -3.25611 |
| MPO | myeloperoxidase | -3.18885 |
| ARL10 | ADP-ribosylation factor-like 10 | -3.13669 |
| TTI2 | TELO2 interacting protein 2 | -3.13451 |
| TSPAN31 | tetraspanin 31 | -3.11879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -3.0897 |
| VIL1 | villin 1 | -3.06536 |
| ACBD6 | acyl-CoA binding domain containing 6 | -3.05559 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -3.04394 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | -2.9934 |
| FAM69B | family with sequence similarity 69, member B | -2.95615 |
| TFRC | transferrin receptor | -2.95134 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.93815 |
| CTSB | cathepsin B | -2.90523 |
| GSE1 | Gse1 coiled-coil protein | -2.88217 |
| FKRP | fukutin related protein | -2.87603 |
| ENOSF1 | enolase superfamily member 1 | -2.84394 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -2.82552 |
| USHBP1 | Usher syndrome 1C binding protein 1 | -2.79355 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -2.75929 |
| MIF4GD | MIF4G domain containing | -2.69569 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.66766 |
| FBXO11 | F-box protein 11 | -2.65449 |
| ACO2 | aconitase 2, mitochondrial | -2.64896 |
| ERCC4 | excision repair cross-complementation group 4 | -2.64361 |
| MLX | MLX, MAX dimerization protein | -2.62182 |
| STK17A | serine/threonine kinase 17a | -2.58292 |
| HIRIP3 | HIRA interacting protein 3 | -2.52989 |
| FANCD2OS | FANCD2 opposite strand | -2.49229 |
| RPL21 | ribosomal protein L21 | -2.43839 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -2.40399 |
| ZNF593OS | ZNF593 opposite strand | -2.39483 |
| EME1 | essential meiotic structure-specific endonuclease 1 | -2.38481 |
| LRRC75A | leucine rich repeat containing 75A | -2.3843 |
| ENO1 | enolase 1, (alpha) | -2.37599 |
| DHCR24 | 24-dehydrocholesterol reductase | -2.37296 |
| NUCB2 | nucleobindin 2 | -2.37287 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) | -2.31532 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -2.31006 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -2.28611 |
| MRPL47 | mitochondrial ribosomal protein L47 | -2.25435 |
| NPB | neuropeptide B | -2.24682 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | -2.24379 |
| MCMDC2 | minichromosome maintenance domain containing 2 | -2.24379 |
| OTUD4 | OTU deubiquitinase 4 | -2.23935 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | -2.23651 |
| OPN1SW | opsin 1 (cone pigments), short-wave-sensitive | -2.23042 |
| LRRC59 | leucine rich repeat containing 59 | -2.20842 |
| ZC3H14 | zinc finger CCCH-type containing 14 | -2.19588 |
| C12ORF73 | chromosome 12 open reading frame 73 | -2.19051 |
| VRK2 | vaccinia related kinase 2 | -2.18167 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L | -2.17805 |
| PLLP | plasmolipin | -2.17645 |
