| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting UCHL1 in primary fibroblasts cell (Study accession: SRP391900) (PerturbAtlas) |
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65 genes differentially expressed following the Perturb_15114_OE_UCHL1_SRP391900 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 4.28214 |
| ARHGAP24 | Rho GTPase activating protein 24 | 4.28214 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 4.17481 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 3.55659 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 3.53285 |
| INSIG1 | insulin induced gene 1 | 3.40803 |
| KLF6 | Kruppel-like factor 6 | 3.40803 |
| CD276 | CD276 molecule | 3.40803 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 3.40803 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 2.3648 |
| ZBTB22 | zinc finger and BTB domain containing 22 | 2.30072 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 2.04147 |
| JUP | junction plakoglobin | 1.99253 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | 1.99253 |
| LDLR | low density lipoprotein receptor | 1.78506 |
| MYO15B | myosin XVB | 1.66475 |
| MVD | mevalonate (diphospho) decarboxylase | 1.66475 |
| ZNF316 | zinc finger protein 316 | 1.65162 |
| YPEL1 | yippee-like 1 (Drosophila) | 1.61432 |
| TET3 | tet methylcytosine dioxygenase 3 | 1.60225 |
| MXI1 | MAX interactor 1, dimerization protein | 1.59188 |
| RBM12 | RNA binding motif protein 12 | 1.58114 |
| TSPAN11 | tetraspanin 11 | 1.57093 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 1.53087 |
| DCAF16 | DDB1 and CUL4 associated factor 16 | 1.51126 |
| FASN | fatty acid synthase | 1.51126 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 1.48728 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 | 1.48728 |
| FSCN1 | fascin actin-bundling protein 1 | 1.48021 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | 1.47405 |
| C8ORF82 | chromosome 8 open reading frame 82 | 1.47405 |
| RSL24D1 | ribosomal L24 domain containing 1 | 1.44135 |
| PNPLA7 | patatin-like phospholipase domain containing 7 | 1.41091 |
| HTRA1 | HtrA serine peptidase 1 | 1.3727 |
| GBAS | glioblastoma amplified sequence | 1.35552 |
| ZNF345 | zinc finger protein 345 | 1.31524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -4.52576 |
| HEG1 | heart development protein with EGF-like domains 1 | -3.40803 |
| POFUT1 | protein O-fucosyltransferase 1 | -3.40803 |
| GXYLT1 | glucoside xylosyltransferase 1 | -2.98907 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -2.79728 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -2.67916 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -2.09314 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -2.07384 |
| JUNB | jun B proto-oncogene | -1.99253 |
| BMPER | BMP binding endothelial regulator | -1.90597 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -1.89382 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -1.78824 |
| TXNIP | thioredoxin interacting protein | -1.68139 |
| DOCK10 | dedicator of cytokinesis 10 | -1.66475 |
| MMS22L | MMS22-like, DNA repair protein | -1.65162 |
| BTG2 | BTG family, member 2 | -1.61432 |
| SELPLG | selectin P ligand | -1.59375 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -1.51126 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -1.49433 |
| SPRED3 | sprouty-related, EVH1 domain containing 3 | -1.49433 |
| FAM111B | family with sequence similarity 111, member B | -1.48728 |
| C2ORF44 | chromosome 2 open reading frame 44 | -1.48728 |
| HSPA14 | heat shock 70kDa protein 14 | -1.48614 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -1.48401 |
| TUBA1B | tubulin, alpha 1b | -1.48021 |
| E2F2 | E2F transcription factor 2 | -1.47405 |
| CDCA7 | cell division cycle associated 7 | -1.47405 |
| GPN3 | GPN-loop GTPase 3 | -1.47405 |
| CDC25A | cell division cycle 25A | -1.31524 |
