Perturb_15174_KD_LOC157273_SRP238261 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting LOC157273 in primary human hepatocyte tissue (Study accession: SRP238261) (PerturbAtlas)
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Genes

29 genes differentially expressed following the Perturb_15174_KD_LOC157273_SRP238261 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
TUBA1C tubulin, alpha 1c 4.74767
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 4.74767
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 3.57188
PLD4 phospholipase D family, member 4 3.40083
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 3.36466
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.66061
DLD dihydrolipoamide dehydrogenase 2.07645
ZCCHC14 zinc finger, CCHC domain containing 14 2.00239
NANS N-acetylneuraminic acid synthase 1.91051
MKRN2 makorin ring finger protein 2 1.86679
ITGB1BP1 integrin beta 1 binding protein 1 1.58678
CCNK cyclin K 1.55491
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 1.5014
PGF placental growth factor 1.5014
MALSU1 mitochondrial assembly of ribosomal large subunit 1 1.5014
CISD3 CDGSH iron sulfur domain 3 1.5014
MIA3 melanoma inhibitory activity family, member 3 1.50023
MXRA8 matrix-remodelling associated 8 1.43051
MYO7B myosin VIIB 1.43051
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 1.33042
WDR54 WD repeat domain 54 1.33042
PKLR pyruvate kinase, liver and RBC 1.32493

decreased expression

Symbol Name Standardized Value
HMHA1 histocompatibility (minor) HA-1 -3.33638
THAP3 THAP domain containing, apoptosis associated protein 3 -2.80482
TMEM50B transmembrane protein 50B -2.55492
USP30 ubiquitin specific peptidase 30 -2.26358
KCP kielin/chordin-like protein -1.69142
MRPS34 mitochondrial ribosomal protein S34 -1.48842
BDKRB1 bradykinin receptor B1 -1.32493