| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting TRIB1 in Prostate cancer cell lines DU145 cell line (Study accession: SRP176423) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_15425_OE_TRIB1_SRP176423 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 20.0 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 20.0 |
| CNN3 | calponin 3, acidic | 20.0 |
| LBH | limb bud and heart development | 20.0 |
| FBLN1 | fibulin 1 | 20.0 |
| FSCN1 | fascin actin-bundling protein 1 | 20.0 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 20.0 |
| MPG | N-methylpurine-DNA glycosylase | 20.0 |
| BMP4 | bone morphogenetic protein 4 | 20.0 |
| HBEGF | heparin-binding EGF-like growth factor | 20.0 |
| SPTB | spectrin, beta, erythrocytic | 20.0 |
| TRIB1 | tribbles pseudokinase 1 | 20.0 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 20.0 |
| PSAT1 | phosphoserine aminotransferase 1 | 20.0 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 20.0 |
| HES7 | hes family bHLH transcription factor 7 | 20.0 |
| TM4SF1 | transmembrane 4 L six family member 1 | 20.0 |
| MEGF9 | multiple EGF-like-domains 9 | 20.0 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 20.0 |
| TNNC1 | troponin C type 1 (slow) | 20.0 |
| DUSP4 | dual specificity phosphatase 4 | 20.0 |
| KIF5B | kinesin family member 5B | 20.0 |
| MYEOV | myeloma overexpressed | 20.0 |
| THBS1 | thrombospondin 1 | 20.0 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 20.0 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 20.0 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 20.0 |
| PRKCA | protein kinase C, alpha | 20.0 |
| NPNT | nephronectin | 20.0 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 20.0 |
| CES3 | carboxylesterase 3 | 20.0 |
| DNM3 | dynamin 3 | 20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 20.0 |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 | 20.0 |
| STAMBPL1 | STAM binding protein-like 1 | 20.0 |
| MCAM | melanoma cell adhesion molecule | 20.0 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 20.0 |
| ALPPL2 | alkaline phosphatase, placental-like 2 | 20.0 |
| MATN2 | matrilin 2 | 20.0 |
| SDPR | serum deprivation response | 20.0 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 20.0 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 20.0 |
| PARD3 | par-3 family cell polarity regulator | 20.0 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 20.0 |
| ALPP | alkaline phosphatase, placental | 20.0 |
| ENO3 | enolase 3 (beta, muscle) | 20.0 |
| FAM102B | family with sequence similarity 102, member B | 20.0 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 20.0 |
| GPC1 | glypican 1 | 20.0 |
| DUSP13 | dual specificity phosphatase 13 | 19.699 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 19.3979 |
| SELENBP1 | selenium binding protein 1 | 19.301 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 19.301 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 19.2218 |
| ANTXR1 | anthrax toxin receptor 1 | 19.0 |
| ETV5 | ets variant 5 | 18.8239 |
| S100A10 | S100 calcium binding protein A10 | 18.7959 |
| ARL5B | ADP-ribosylation factor-like 5B | 18.585 |
| GPX3 | glutathione peroxidase 3 | 18.5686 |
| MTSS1L | metastasis suppressor 1-like | 18.4949 |
| SFMBT2 | Scm-like with four mbt domains 2 | 18.4559 |
| NRCAM | neuronal cell adhesion molecule | 18.3188 |
| GJA3 | gap junction protein, alpha 3, 46kDa | 17.7773 |
| FOLR1 | folate receptor 1 (adult) | 17.7773 |
| REEP2 | receptor accessory protein 2 | 17.6596 |
| FERMT2 | fermitin family member 2 | 17.3979 |
| DNM1 | dynamin 1 | 17.1101 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 17.1101 |
| WWTR1 | WW domain containing transcription regulator 1 | 17.0372 |
| CGN | cingulin | 17.0101 |
| PCID2 | PCI domain containing 2 | 17.0052 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 16.983 |
| JUP | junction plakoglobin | 16.923 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 16.7254 |
| PHGDH | phosphoglycerate dehydrogenase | 16.7022 |
| P3H2 | prolyl 3-hydroxylase 2 | 16.6735 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 16.5045 |
| CDR2L | cerebellar degeneration-related protein 2-like | 16.4924 |
| RPS29 | ribosomal protein S29 | 16.3325 |
| AXL | AXL receptor tyrosine kinase | 16.2631 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 16.2586 |
| CMIP | c-Maf inducing protein | 16.0427 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | 15.9916 |
| PKP4 | plakophilin 4 | 15.9455 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 15.2053 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 14.6027 |
| CCND1 | cyclin D1 | 14.5498 |
| TMEM56 | transmembrane protein 56 | 14.5445 |
| GAL | galanin/GMAP prepropeptide | 14.5256 |
| MMP28 | matrix metallopeptidase 28 | 14.4892 |
| LIMCH1 | LIM and calponin homology domains 1 | 14.3008 |
| PPME1 | protein phosphatase methylesterase 1 | 14.0957 |
| EGF | epidermal growth factor | 14.0637 |
| WRB | tryptophan rich basic protein | 14.0387 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 | 13.9716 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled | 13.9612 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | 13.6955 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 13.6514 |
| LRRC59 | leucine rich repeat containing 59 | 13.6064 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 13.2983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALCAM | activated leukocyte cell adhesion molecule | -20.0 |
| LAMC2 | laminin, gamma 2 | -20.0 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -20.0 |
| IER3 | immediate early response 3 | -20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -20.0 |
| TPBG | trophoblast glycoprotein | -20.0 |
| PTGES | prostaglandin E synthase | -20.0 |
| IFITM3 | interferon induced transmembrane protein 3 | -20.0 |
| FAM83A | family with sequence similarity 83, member A | -20.0 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -20.0 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -20.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | -20.0 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 | -20.0 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -20.0 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -20.0 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -20.0 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -20.0 |
| BIRC3 | baculoviral IAP repeat containing 3 | -20.0 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -20.0 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -20.0 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -20.0 |
| TNIP1 | TNFAIP3 interacting protein 1 | -20.0 |
| TNC | tenascin C | -20.0 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -20.0 |
| NAMPT | nicotinamide phosphoribosyltransferase | -20.0 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -20.0 |
| C3 | complement component 3 | -20.0 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -20.0 |
| MGLL | monoglyceride lipase | -20.0 |
| PTK2B | protein tyrosine kinase 2 beta | -20.0 |
| CSF1 | colony stimulating factor 1 (macrophage) | -20.0 |
| LAMA3 | laminin, alpha 3 | -20.0 |
| TAPBP | TAP binding protein (tapasin) | -20.0 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -20.0 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -20.0 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -20.0 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -20.0 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -20.0 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -20.0 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -20.0 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -20.0 |
| ISG15 | ISG15 ubiquitin-like modifier | -20.0 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -20.0 |
| SLPI | secretory leukocyte peptidase inhibitor | -20.0 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -20.0 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -20.0 |
| RUNX1 | runt-related transcription factor 1 | -20.0 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -20.0 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -20.0 |
| ITGA1 | integrin, alpha 1 | -20.0 |
| IFI44 | interferon-induced protein 44 | -20.0 |
| MT2A | metallothionein 2A | -20.0 |
| PLSCR1 | phospholipid scramblase 1 | -20.0 |
| TMEM132A | transmembrane protein 132A | -20.0 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -20.0 |
| DOC2A | double C2-like domains, alpha | -20.0 |
| MGST1 | microsomal glutathione S-transferase 1 | -20.0 |
| IFIH1 | interferon induced with helicase C domain 1 | -20.0 |
| TRIM25 | tripartite motif containing 25 | -20.0 |
| C1RL | complement component 1, r subcomponent-like | -20.0 |
| LCN2 | lipocalin 2 | -20.0 |
| ADAM8 | ADAM metallopeptidase domain 8 | -20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -20.0 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -20.0 |
| BCL3 | B-cell CLL/lymphoma 3 | -20.0 |
| TSPAN15 | tetraspanin 15 | -20.0 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -20.0 |
| CTSB | cathepsin B | -20.0 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -20.0 |
| SAMD9 | sterile alpha motif domain containing 9 | -20.0 |
| PFKL | phosphofructokinase, liver | -20.0 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -20.0 |
| MMD | monocyte to macrophage differentiation-associated | -20.0 |
| HLA-C | major histocompatibility complex, class I, C | -20.0 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -20.0 |
| SDC4 | syndecan 4 | -20.0 |
| VEGFA | vascular endothelial growth factor A | -20.0 |
| CYBRD1 | cytochrome b reductase 1 | -20.0 |
| OSMR | oncostatin M receptor | -20.0 |
| MLF2 | myeloid leukemia factor 2 | -20.0 |
| FN1 | fibronectin 1 | -20.0 |
| C1S | complement component 1, s subcomponent | -20.0 |
| IFI6 | interferon, alpha-inducible protein 6 | -20.0 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -20.0 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -20.0 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -20.0 |
| HHIPL2 | HHIP-like 2 | -20.0 |
| NNMT | nicotinamide N-methyltransferase | -20.0 |
| TGM2 | transglutaminase 2 | -20.0 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -20.0 |
| ANXA8 | annexin A8 | -20.0 |
| IL32 | interleukin 32 | -20.0 |
| CDCP1 | CUB domain containing protein 1 | -20.0 |
| NLRP12 | NLR family, pyrin domain containing 12 | -20.0 |
| ICAM1 | intercellular adhesion molecule 1 | -20.0 |
| PARP10 | poly (ADP-ribose) polymerase family, member 10 | -20.0 |
| TMEM178B | transmembrane protein 178B | -19.699 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -19.699 |
| MX1 | MX dynamin-like GTPase 1 | -19.699 |
