Perturb_15453_KO_KLF4_SRP155901 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KO perturbation targeting KLF4 in prostate cancer cell PC3 cell line (Study accession: SRP155901) (PerturbAtlas)
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Genes

39 genes differentially expressed following the Perturb_15453_KO_KLF4_SRP155901 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
BMP6 bone morphogenetic protein 6 2.85892
CXCL8 chemokine (C-X-C motif) ligand 8 2.71345
GPR39 G protein-coupled receptor 39 2.4593
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.26405
PINK1 PTEN induced putative kinase 1 1.43203
TRABD2A TraB domain containing 2A 1.43083
NPC1 Niemann-Pick disease, type C1 1.39644

decreased expression

Symbol Name Standardized Value
LGALS8 lectin, galactoside-binding, soluble, 8 -8.41121
TBCE tubulin folding cofactor E -7.51637
SH3PXD2A SH3 and PX domains 2A -6.84284
COX20 COX20 cytochrome c oxidase assembly factor -4.26021
HEATR1 HEAT repeat containing 1 -4.26021
CCL15 chemokine (C-C motif) ligand 15 -4.24679
BOLA1 bolA family member 1 -4.15477
FGF14 fibroblast growth factor 14 -3.77164
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -3.40626
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 -3.36403
FANCD2OS FANCD2 opposite strand -2.98141
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF -2.87162
NR2C2 nuclear receptor subfamily 2, group C, member 2 -2.35434
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) -2.23315
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -2.1699
GLRX2 glutaredoxin 2 -2.1224
FAM166A family with sequence similarity 166, member A -2.05925
HOXA10 homeobox A10 -2.05881
C16ORF70 chromosome 16 open reading frame 70 -1.91262
FSIP1 fibrous sheath interacting protein 1 -1.82861
SZT2 seizure threshold 2 homolog (mouse) -1.7584
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -1.70142
JMJD4 jumonji domain containing 4 -1.67914
SSPN sarcospan -1.58447
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -1.58447
MRPS25 mitochondrial ribosomal protein S25 -1.55598
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing -1.54188
KIAA0895 KIAA0895 -1.43083
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -1.38753
ORAOV1 oral cancer overexpressed 1 -1.32025
C1ORF56 chromosome 1 open reading frame 56 -1.31405
CLVS1 clavesin 1 -1.30644