| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting NUSAP1 in prostatic carcinoma DU145 brain metastasis cell line (Study accession: SRP074246) (PerturbAtlas) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perturb_15574_KD_NUSAP1_SRP074246 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CAPN2 | calpain 2, (m/II) large subunit | 20.0 |
| FGFR1 | fibroblast growth factor receptor 1 | 20.0 |
| SAV1 | salvador family WW domain containing protein 1 | 20.0 |
| ADAMTSL4 | ADAMTS-like 4 | 20.0 |
| TMEM79 | transmembrane protein 79 | 20.0 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 20.0 |
| CSNK1D | casein kinase 1, delta | 20.0 |
| OR2I1P | olfactory receptor, family 2, subfamily I, member 1 pseudogene | 20.0 |
| SPTB | spectrin, beta, erythrocytic | 20.0 |
| TLDC2 | TBC/LysM-associated domain containing 2 | 20.0 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 20.0 |
| FAM65C | family with sequence similarity 65, member C | 20.0 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | 20.0 |
| SYTL4 | synaptotagmin-like 4 | 20.0 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 | 20.0 |
| PDZD8 | PDZ domain containing 8 | 20.0 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | 20.0 |
| SH2D2A | SH2 domain containing 2A | 20.0 |
| ZNF444 | zinc finger protein 444 | 20.0 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 20.0 |
| RPL10 | ribosomal protein L10 | 20.0 |
| TOR3A | torsin family 3, member A | 20.0 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | 20.0 |
| IL12RB2 | interleukin 12 receptor, beta 2 | 20.0 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 20.0 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | 20.0 |
| RNF214 | ring finger protein 214 | 20.0 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 20.0 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | 20.0 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 20.0 |
| TTC19 | tetratricopeptide repeat domain 19 | 20.0 |
| TICRR | TOPBP1-interacting checkpoint and replication regulator | 20.0 |
| CTC1 | CTS telomere maintenance complex component 1 | 20.0 |
| ACO1 | aconitase 1, soluble | 20.0 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 20.0 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 20.0 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 20.0 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | 20.0 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 20.0 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 20.0 |
| LIG3 | ligase III, DNA, ATP-dependent | 20.0 |
| UBXN11 | UBX domain protein 11 | 20.0 |
| CCNI2 | cyclin I family, member 2 | 20.0 |
| BTBD2 | BTB (POZ) domain containing 2 | 20.0 |
| C14ORF166 | chromosome 14 open reading frame 166 | 20.0 |
| FCHSD1 | FCH and double SH3 domains 1 | 20.0 |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase | 19.699 |
| ATXN2 | ataxin 2 | 18.9586 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) | 18.9208 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | 18.4202 |
| KIAA1614 | KIAA1614 | 18.3565 |
| PARD6G | par-6 family cell polarity regulator gamma | 17.9393 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 17.7212 |
| MTERF2 | mitochondrial transcription termination factor 2 | 17.5884 |
| LRRC34 | leucine rich repeat containing 34 | 17.4089 |
| C16ORF70 | chromosome 16 open reading frame 70 | 17.3335 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 17.055 |
| NUP50 | nucleoporin 50kDa | 17.0195 |
| CCDC159 | coiled-coil domain containing 159 | 16.9527 |
| CSF1R | colony stimulating factor 1 receptor | 16.8182 |
| C22ORF23 | chromosome 22 open reading frame 23 | 16.0296 |
| B9D1 | B9 protein domain 1 | 15.9847 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 15.7396 |
| DFNA5 | deafness, autosomal dominant 5 | 15.7129 |
| HRNR | hornerin | 15.6839 |
| GLS | glutaminase | 15.5207 |
| TSFM | Ts translation elongation factor, mitochondrial | 15.1578 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 14.9921 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 14.854 |
| DNM2 | dynamin 2 | 14.774 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 14.6981 |
| MFSD7 | major facilitator superfamily domain containing 7 | 14.4891 |
| IGSF10 | immunoglobulin superfamily, member 10 | 14.4871 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 14.481 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 | 14.3976 |
| RBBP4 | retinoblastoma binding protein 4 | 14.329 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 14.2994 |
| SGSM2 | small G protein signaling modulator 2 | 14.1529 |
| KHK | ketohexokinase (fructokinase) | 13.999 |
| TUBA1C | tubulin, alpha 1c | 13.8882 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 13.8797 |
| SMTNL1 | smoothelin-like 1 | 13.7934 |
| MYH10 | myosin, heavy chain 10, non-muscle | 13.4212 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) | 13.0984 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 13.0921 |
| BEST1 | bestrophin 1 | 13.0525 |
| SLC5A10 | solute carrier family 5 (sodium/sugar cotransporter), member 10 | 12.32 |
| AANAT | aralkylamine N-acetyltransferase | 12.1542 |
| QRFP | pyroglutamylated RFamide peptide | 12.1057 |
| COX20 | COX20 cytochrome c oxidase assembly factor | 12.0892 |
| TBPL1 | TBP-like 1 | 12.0724 |
| SPON1 | spondin 1, extracellular matrix protein | 11.9098 |
| CDHR2 | cadherin-related family member 2 | 11.8169 |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | 11.7971 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 11.6043 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 11.5307 |
| CARD14 | caspase recruitment domain family, member 14 | 11.4795 |
| TMEM180 | transmembrane protein 180 | 11.3717 |
| PHACTR3 | phosphatase and actin regulator 3 | 11.3614 |
| SDS | serine dehydratase | 11.3449 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MLX | MLX, MAX dimerization protein | -20.0 |
| DNASE1 | deoxyribonuclease I | -20.0 |
| KIF2A | kinesin heavy chain member 2A | -20.0 |
| SBF2 | SET binding factor 2 | -20.0 |
| FAM57A | family with sequence similarity 57, member A | -20.0 |
| ZNF263 | zinc finger protein 263 | -20.0 |
| FANCD2OS | FANCD2 opposite strand | -20.0 |
| WDR20 | WD repeat domain 20 | -20.0 |
| CDC14B | cell division cycle 14B | -20.0 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | -20.0 |
| SCLT1 | sodium channel and clathrin linker 1 | -20.0 |
| CCNK | cyclin K | -20.0 |
| AFG3L2 | AFG3-like AAA ATPase 2 | -20.0 |
| VPS9D1 | VPS9 domain containing 1 | -20.0 |
| EXOSC9 | exosome component 9 | -20.0 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) | -20.0 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -20.0 |
| CLCC1 | chloride channel CLIC-like 1 | -20.0 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -20.0 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -20.0 |
| ENOSF1 | enolase superfamily member 1 | -20.0 |
| C16ORF62 | chromosome 16 open reading frame 62 | -20.0 |
| SRR | serine racemase | -20.0 |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha | -20.0 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -20.0 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -20.0 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 | -20.0 |
| WTAP | Wilms tumor 1 associated protein | -20.0 |
| PAX9 | paired box 9 | -20.0 |
| SYCP3 | synaptonemal complex protein 3 | -20.0 |
| TCP1 | t-complex 1 | -20.0 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -20.0 |
| FZD4 | frizzled class receptor 4 | -20.0 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -20.0 |
| KDM8 | lysine (K)-specific demethylase 8 | -20.0 |
| TRIM59 | tripartite motif containing 59 | -20.0 |
| FANCL | Fanconi anemia, complementation group L | -20.0 |
| GPS2 | G protein pathway suppressor 2 | -20.0 |
| CCDC107 | coiled-coil domain containing 107 | -20.0 |
| ZNF276 | zinc finger protein 276 | -20.0 |
| ADCY7 | adenylate cyclase 7 | -20.0 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 | -20.0 |
| KLC1 | kinesin light chain 1 | -20.0 |
| ADCY3 | adenylate cyclase 3 | -20.0 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -20.0 |
| LHFPL5 | lipoma HMGIC fusion partner-like 5 | -20.0 |
| SRRM2 | serine/arginine repetitive matrix 2 | -20.0 |
| KRT8 | keratin 8, type II | -20.0 |
| KIAA0895 | KIAA0895 | -20.0 |
| TSPAN31 | tetraspanin 31 | -20.0 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -20.0 |
| C12ORF65 | chromosome 12 open reading frame 65 | -20.0 |
| PDGFRL | platelet-derived growth factor receptor-like | -20.0 |
| ANAPC10 | anaphase promoting complex subunit 10 | -19.1549 |
| OTUD4 | OTU deubiquitinase 4 | -19.0969 |
| SLC9B1 | solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 | -19.0 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | -18.8861 |
| GLIPR1 | GLI pathogenesis-related 1 | -18.8539 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -18.3468 |
| IFT80 | intraflagellar transport 80 | -18.3468 |
| FSIP1 | fibrous sheath interacting protein 1 | -18.1805 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -18.1427 |
| RUFY1 | RUN and FYVE domain containing 1 | -17.7122 |
| METTL20 | methyltransferase like 20 | -17.6162 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -17.5482 |
| RBM25 | RNA binding motif protein 25 | -17.5214 |
| TMEM80 | transmembrane protein 80 | -17.4868 |
| ALG1 | ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase | -17.4214 |
| CNTD1 | cyclin N-terminal domain containing 1 | -17.3655 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -17.1669 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | -17.1391 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -17.0218 |
| C19ORF54 | chromosome 19 open reading frame 54 | -16.8668 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -16.7997 |
| FHOD3 | formin homology 2 domain containing 3 | -16.3806 |
| TMEM140 | transmembrane protein 140 | -15.567 |
| PDZD11 | PDZ domain containing 11 | -15.4995 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -15.3806 |
| TVP23A | trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) | -15.3006 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific | -15.1309 |
| ASB14 | ankyrin repeat and SOCS box containing 14 | -15.0965 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 | -14.9278 |
| CINP | cyclin-dependent kinase 2 interacting protein | -14.5188 |
| SCAI | suppressor of cancer cell invasion | -14.4062 |
| HERPUD2 | HERPUD family member 2 | -14.351 |
| BRI3 | brain protein I3 | -14.2511 |
| METTL5 | methyltransferase like 5 | -14.0196 |
| C9ORF16 | chromosome 9 open reading frame 16 | -13.4763 |
| XRRA1 | X-ray radiation resistance associated 1 | -13.3896 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -12.9684 |
| MAX | MYC associated factor X | -12.9467 |
| USP34 | ubiquitin specific peptidase 34 | -12.8432 |
| SEPT2 | septin 2 | -12.8129 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -12.5383 |
| SPSB2 | splA/ryanodine receptor domain and SOCS box containing 2 | -12.4302 |
| EFCAB10 | EF-hand calcium binding domain 10 | -12.3392 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -12.2271 |
| HAS3 | hyaluronan synthase 3 | -12.1291 |
| EXOC3 | exocyst complex component 3 | -12.1057 |
| RCE1 | Ras converting CAAX endopeptidase 1 | -12.017 |
