Perturb_15861_KD_ETS1_SRP270313 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting ETS1 in Rh41 cell line (Study accession: SRP270313) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_15861_KD_ETS1_SRP270313 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
MYOM1 myomesin 1 20.0
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 20.0
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 20.0
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 20.0
LINC00514 long intergenic non-protein coding RNA 514 20.0
NCALD neurocalcin delta 20.0
SRL sarcalumenin 20.0
LPPR2 lipid phosphate phosphatase-related protein type 2 20.0
DOT1L DOT1-like histone H3K79 methyltransferase 20.0
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 20.0
KLHL30 kelch-like family member 30 20.0
PITPNM3 PITPNM family member 3 20.0
TNNI2 troponin I type 2 (skeletal, fast) 20.0
TNNT3 troponin T type 3 (skeletal, fast) 20.0
SIRT2 sirtuin 2 20.0
MFAP4 microfibrillar-associated protein 4 20.0
NEU4 sialidase 4 20.0
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 20.0
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 20.0
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 20.0
CCDC141 coiled-coil domain containing 141 20.0
FAM65B family with sequence similarity 65, member B 20.0
MYBPC2 myosin binding protein C, fast type 20.0
SYNPO2L synaptopodin 2-like 20.0
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 20.0
RAB11FIP4 RAB11 family interacting protein 4 (class II) 20.0
HR hair growth associated 20.0
RD3 retinal degeneration 3 20.0
TNNC1 troponin C type 1 (slow) 20.0
TNNC2 troponin C type 2 (fast) 20.0
LDB3 LIM domain binding 3 20.0
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 20.0
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 20.0
COL24A1 collagen, type XXIV, alpha 1 20.0
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 20.0
CAPN6 calpain 6 20.0
SMPX small muscle protein, X-linked 20.0
MYPN myopalladin 20.0
DOK7 docking protein 7 20.0
CKM creatine kinase, muscle 20.0
CBLN2 cerebellin 2 precursor 20.0
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 20.0
MYOG myogenin (myogenic factor 4) 20.0
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 20.0
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 20.0
C7 complement component 7 20.0
SAMD11 sterile alpha motif domain containing 11 20.0
FAM107A family with sequence similarity 107, member A 20.0
MVB12B multivesicular body subunit 12B 20.0
GBP2 guanylate binding protein 2, interferon-inducible 20.0
CASQ2 calsequestrin 2 (cardiac muscle) 20.0
TRIM54 tripartite motif containing 54 20.0
MRAS muscle RAS oncogene homolog 20.0
AFAP1L2 actin filament associated protein 1-like 2 20.0
C9ORF172 chromosome 9 open reading frame 172 20.0
KLHL41 kelch-like family member 41 20.0
ADGRA1 adhesion G protein-coupled receptor A1 20.0
SYN2 synapsin II 20.0
LOC285556 uncharacterized LOC285556 20.0
IGFBP5 insulin-like growth factor binding protein 5 20.0
PALMD palmdelphin 20.0
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 20.0
LMOD3 leiomodin 3 (fetal) 20.0
CREB3L2 cAMP responsive element binding protein 3-like 2 20.0
ACTN2 actinin, alpha 2 20.0
ABLIM3 actin binding LIM protein family, member 3 20.0
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 20.0
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 20.0
MYLK4 myosin light chain kinase family, member 4 20.0
XIRP1 xin actin binding repeat containing 1 20.0
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 20.0
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 20.0
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 20.0
THNSL2 threonine synthase-like 2 (S. cerevisiae) 20.0
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 20.0
SMYD1 SET and MYND domain containing 1 20.0
MYL1 myosin, light chain 1, alkali; skeletal, fast 20.0
HFE2 hemochromatosis type 2 (juvenile) 20.0
SEC24D SEC24 family member D 20.0
STC1 stanniocalcin 1 20.0
PDE4DIP phosphodiesterase 4D interacting protein 20.0
ARPP21 cAMP-regulated phosphoprotein, 21kDa 20.0
PARM1 prostate androgen-regulated mucin-like protein 1 20.0
RGL4 ral guanine nucleotide dissociation stimulator-like 4 20.0
UNC45B unc-45 homolog B (C. elegans) 20.0
TMEM63C transmembrane protein 63C 20.0
MYL4 myosin, light chain 4, alkali; atrial, embryonic 20.0
RXRG retinoid X receptor, gamma 20.0
HRC histidine rich calcium binding protein 20.0
HSPB3 heat shock 27kDa protein 3 20.0
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 20.0
MAPK10 mitogen-activated protein kinase 10 20.0
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 20.0
MYBPH myosin binding protein H 20.0
TNRC18 trinucleotide repeat containing 18 20.0
COL5A3 collagen, type V, alpha 3 20.0
MYOZ2 myozenin 2 20.0
TMEM8C transmembrane protein 8C 20.0
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 20.0
MYOM3 myomesin 3 20.0

decreased expression

Symbol Name Standardized Value
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) -20.0
FAM131B family with sequence similarity 131, member B -20.0
SPRY4 sprouty homolog 4 (Drosophila) -20.0
TCHH trichohyalin -20.0
AKR1C3 aldo-keto reductase family 1, member C3 -20.0
SEZ6 seizure related 6 homolog (mouse) -20.0
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -20.0
CCM2L cerebral cavernous malformation 2-like -20.0
SOX9 SRY (sex determining region Y)-box 9 -20.0
LAPTM5 lysosomal protein transmembrane 5 -20.0
NDRG1 N-myc downstream regulated 1 -20.0
LMO2 LIM domain only 2 (rhombotin-like 1) -20.0
TES testin LIM domain protein -20.0
C12ORF75 chromosome 12 open reading frame 75 -20.0
PLXNA4 plexin A4 -20.0
ETV4 ets variant 4 -20.0
BMP4 bone morphogenetic protein 4 -20.0
FAM49A family with sequence similarity 49, member A -20.0
TUFT1 tuftelin 1 -20.0
IGFBP6 insulin-like growth factor binding protein 6 -20.0
STX3 syntaxin 3 -20.0
PLK2 polo-like kinase 2 -20.0
NQO1 NAD(P)H dehydrogenase, quinone 1 -20.0
GMFG glia maturation factor, gamma -20.0
LOX lysyl oxidase -20.0
PTPRE protein tyrosine phosphatase, receptor type, E -20.0
GPSM3 G-protein signaling modulator 3 -20.0
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -20.0
THBS1 thrombospondin 1 -20.0
RAB3B RAB3B, member RAS oncogene family -20.0
SHROOM4 shroom family member 4 -20.0
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -20.0
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -20.0
DUSP6 dual specificity phosphatase 6 -20.0
CADM4 cell adhesion molecule 4 -20.0
NTM neurotrimin -20.0
ASIC2 acid sensing (proton gated) ion channel 2 -20.0
ARHGAP19 Rho GTPase activating protein 19 -20.0
VSIG10 V-set and immunoglobulin domain containing 10 -20.0
TLE4 transducin-like enhancer of split 4 -20.0
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -20.0
LTBP2 latent transforming growth factor beta binding protein 2 -20.0
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -20.0
TMEM233 transmembrane protein 233 -20.0
IL27RA interleukin 27 receptor, alpha -20.0
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 -20.0
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -20.0
RUNX2 runt-related transcription factor 2 -20.0
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -20.0
MYO5B myosin VB -20.0
ITGA6 integrin, alpha 6 -20.0
TLL2 tolloid-like 2 -20.0
S100A16 S100 calcium binding protein A16 -20.0
TNXB tenascin XB -20.0
RGS16 regulator of G-protein signaling 16 -20.0
PLAU plasminogen activator, urokinase -20.0
NOG noggin -20.0
TMEM132B transmembrane protein 132B -20.0
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -20.0
APOE apolipoprotein E -20.0
CAV2 caveolin 2 -20.0
OLFML3 olfactomedin-like 3 -20.0
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -20.0
CDH18 cadherin 18, type 2 -20.0
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -20.0
PPP1R26 protein phosphatase 1, regulatory subunit 26 -20.0
LAMB3 laminin, beta 3 -20.0
COL27A1 collagen, type XXVII, alpha 1 -20.0
CPXM1 carboxypeptidase X (M14 family), member 1 -20.0
TRAPPC8 trafficking protein particle complex 8 -20.0
SPRED3 sprouty-related, EVH1 domain containing 3 -20.0
SFRP4 secreted frizzled-related protein 4 -20.0
EMP1 epithelial membrane protein 1 -20.0
PFKP phosphofructokinase, platelet -20.0
CAV1 caveolin 1, caveolae protein, 22kDa -20.0
NBPF3 neuroblastoma breakpoint family, member 3 -20.0
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -20.0
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -20.0
CEP41 centrosomal protein 41kDa -20.0
ENG endoglin -20.0
FLT1 fms-related tyrosine kinase 1 -20.0
ELMOD1 ELMO/CED-12 domain containing 1 -20.0
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -20.0
COL2A1 collagen, type II, alpha 1 -20.0
EPHB1 EPH receptor B1 -20.0
RASIP1 Ras interacting protein 1 -20.0
GALC galactosylceramidase -20.0
PSAT1 phosphoserine aminotransferase 1 -20.0
DDAH1 dimethylarginine dimethylaminohydrolase 1 -20.0
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -20.0
HMOX1 heme oxygenase 1 -20.0
ARFGEF3 ARFGEF family member 3 -20.0
DMBT1 deleted in malignant brain tumors 1 -20.0
TIMP3 TIMP metallopeptidase inhibitor 3 -20.0
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -20.0
FADS3 fatty acid desaturase 3 -20.0
NPAS1 neuronal PAS domain protein 1 -20.0
NNMT nicotinamide N-methyltransferase -20.0
EGLN3 egl-9 family hypoxia-inducible factor 3 -20.0
DSCAM Down syndrome cell adhesion molecule -20.0