Perturb_15872_KO_SMARCA4_SRP293781 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KO perturbation targeting SMARCA4 in rhabdomyosarcoma RH4 cell line cell line (Study accession: SRP293781) (PerturbAtlas)
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Genes

59 genes differentially expressed following the Perturb_15872_KO_SMARCA4_SRP293781 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
WRNIP1 Werner helicase interacting protein 1 7.73263
C10ORF10 chromosome 10 open reading frame 10 6.64353
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 6.00362
TTC28 tetratricopeptide repeat domain 28 4.9596
KAT6A K(lysine) acetyltransferase 6A 4.47517
ZNF804A zinc finger protein 804A 3.64012
HIPK4 homeodomain interacting protein kinase 4 2.67004
TCP11 t-complex 11, testis-specific 2.62583
MFSD7 major facilitator superfamily domain containing 7 2.50233
ZFYVE16 zinc finger, FYVE domain containing 16 2.28896
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.28699
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.25042
CAPN3 calpain 3, (p94) 2.23226
ADGRG5 adhesion G protein-coupled receptor G5 2.1586
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 2.11548
SAPCD2 suppressor APC domain containing 2 2.10746
CCDC54 coiled-coil domain containing 54 2.09038
ACTC1 actin, alpha, cardiac muscle 1 2.02024
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 2.00675
LYRM2 LYR motif containing 2 1.96542
TMEM244 transmembrane protein 244 1.89597
PRR33 proline rich 33 1.89569
TPRG1 tumor protein p63 regulated 1 1.81651
ULK2 unc-51 like autophagy activating kinase 2 1.76348
BCAN brevican 1.68779
FASTKD1 FAST kinase domains 1 1.63894
HHATL hedgehog acyltransferase-like 1.49357
CCDC43 coiled-coil domain containing 43 1.49357
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.4114
KIAA1671 KIAA1671 1.39064
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.36886
KRTAP3-2 keratin associated protein 3-2 1.32991

decreased expression

Symbol Name Standardized Value
HDGFRP3 hepatoma-derived growth factor, related protein 3 -4.22253
SLC19A1 solute carrier family 19 (folate transporter), member 1 -4.13944
LMF1 lipase maturation factor 1 -3.7461
C10ORF105 chromosome 10 open reading frame 105 -3.36043
ZNF275 zinc finger protein 275 -2.57336
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.4851
BOLA1 bolA family member 1 -2.4851
SYT7 synaptotagmin VII -2.4851
TMEM186 transmembrane protein 186 -2.29409
ISLR immunoglobulin superfamily containing leucine-rich repeat -2.11548
DCP2 decapping mRNA 2 -1.96542
C1QTNF1 C1q and tumor necrosis factor related protein 1 -1.91812
HINT2 histidine triad nucleotide binding protein 2 -1.89569
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -1.88479
NCOA3 nuclear receptor coactivator 3 -1.86263
GRIK3 glutamate receptor, ionotropic, kainate 3 -1.76348
DLD dihydrolipoamide dehydrogenase -1.66965
SPTB spectrin, beta, erythrocytic -1.64999
VIPR2 vasoactive intestinal peptide receptor 2 -1.64999
EPHA1 EPH receptor A1 -1.54697
KRT40 keratin 40, type I -1.47732
MYBPHL myosin binding protein H-like -1.35441
RAP1GAP2 RAP1 GTPase activating protein 2 -1.35193
PHGDH phosphoglycerate dehydrogenase -1.34607
FAM81A family with sequence similarity 81, member A -1.32991
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.32991
CCDC154 coiled-coil domain containing 154 -1.32215