| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting Pou2f3 in small cell lung cancer tuft variant NCIH1048 cell line (Study accession: SRP343255) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_16516_KD_Pou2f3_SRP343255 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPNS2 | spinster homolog 2 (Drosophila) | 20.0 |
| KRT19 | keratin 19, type I | 20.0 |
| KRT13 | keratin 13, type I | 20.0 |
| KRT15 | keratin 15, type I | 20.0 |
| GRHL3 | grainyhead-like 3 (Drosophila) | 20.0 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 20.0 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 20.0 |
| KRT5 | keratin 5, type II | 20.0 |
| SULF2 | sulfatase 2 | 20.0 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 20.0 |
| BMF | Bcl2 modifying factor | 20.0 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 20.0 |
| PLK2 | polo-like kinase 2 | 20.0 |
| TNS3 | tensin 3 | 20.0 |
| PRSS23 | protease, serine, 23 | 20.0 |
| NPR3 | natriuretic peptide receptor 3 | 20.0 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 20.0 |
| PPAP2B | phosphatidic acid phosphatase type 2B | 20.0 |
| NELL1 | NEL-like 1 (chicken) | 20.0 |
| GPNMB | glycoprotein (transmembrane) nmb | 20.0 |
| KRT28 | keratin 28, type I | 20.0 |
| AQP1 | aquaporin 1 (Colton blood group) | 20.0 |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | 20.0 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 20.0 |
| ZNF703 | zinc finger protein 703 | 20.0 |
| KRT9 | keratin 9, type I | 20.0 |
| COL17A1 | collagen, type XVII, alpha 1 | 20.0 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 20.0 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 20.0 |
| CD44 | CD44 molecule (Indian blood group) | 20.0 |
| HES1 | hes family bHLH transcription factor 1 | 20.0 |
| MGP | matrix Gla protein | 20.0 |
| BOC | BOC cell adhesion associated, oncogene regulated | 20.0 |
| MYOF | myoferlin | 20.0 |
| CYP4X1 | cytochrome P450, family 4, subfamily X, polypeptide 1 | 20.0 |
| SGK223 | homolog of rat pragma of Rnd2 | 20.0 |
| LIPG | lipase, endothelial | 20.0 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 20.0 |
| TSKU | tsukushi, small leucine rich proteoglycan | 20.0 |
| POF1B | premature ovarian failure, 1B | 20.0 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 20.0 |
| PLXNA2 | plexin A2 | 19.3979 |
| MLF2 | myeloid leukemia factor 2 | 19.2218 |
| KRT18 | keratin 18, type I | 18.2007 |
| PCDH7 | protocadherin 7 | 18.0362 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 18.0315 |
| PVRL4 | poliovirus receptor-related 4 | 17.2262 |
| PTHLH | parathyroid hormone-like hormone | 17.2175 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 17.1707 |
| KRT1 | keratin 1, type II | 16.7908 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 16.7724 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 16.5522 |
| THSD4 | thrombospondin, type I, domain containing 4 | 16.5174 |
| PLAU | plasminogen activator, urokinase | 16.0356 |
| STAC2 | SH3 and cysteine rich domain 2 | 15.8935 |
| DLX3 | distal-less homeobox 3 | 14.9938 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 14.8865 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 14.7028 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 14.6624 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 14.589 |
| FOSL2 | FOS-like antigen 2 | 14.5426 |
| PRNP | prion protein | 14.414 |
| WNT6 | wingless-type MMTV integration site family, member 6 | 14.3474 |
| FZD4 | frizzled class receptor 4 | 14.3474 |
| STON2 | stonin 2 | 14.2941 |
| FGFR2 | fibroblast growth factor receptor 2 | 14.2181 |
| FRMD6 | FERM domain containing 6 | 14.1861 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 14.0473 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 13.3487 |
| PTCH1 | patched 1 | 13.1106 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | 13.091 |
| SERINC5 | serine incorporator 5 | 12.9476 |
| LYPD1 | LY6/PLAUR domain containing 1 | 12.7075 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 12.7075 |
| PERP | PERP, TP53 apoptosis effector | 12.6266 |
| CD24 | CD24 molecule | 12.5441 |
| FOXQ1 | forkhead box Q1 | 12.3004 |
| KRT17 | keratin 17, type I | 12.211 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 12.1897 |
| KRT16 | keratin 16, type I | 11.8655 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 11.8146 |
| COL12A1 | collagen, type XII, alpha 1 | 11.6758 |
| PTPRU | protein tyrosine phosphatase, receptor type, U | 11.4797 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 11.2036 |
| NTNG1 | netrin G1 | 11.1411 |
| MCC | mutated in colorectal cancers | 10.9934 |
| YAP1 | Yes-associated protein 1 | 10.9373 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 10.805 |
| ANXA2 | annexin A2 | 10.7729 |
| FBLN1 | fibulin 1 | 10.7516 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 10.674 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 10.6224 |
| HR | hair growth associated | 10.4785 |
| RHOB | ras homolog family member B | 10.4307 |
| DDIT4 | DNA-damage-inducible transcript 4 | 10.4072 |
| IFI16 | interferon, gamma-inducible protein 16 | 10.2766 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 10.1339 |
| ACSS1 | acyl-CoA synthetase short-chain family member 1 | 9.91664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LRMP | lymphoid-restricted membrane protein | -20.0 |
| FOXI1 | forkhead box I1 | -20.0 |
| HEPACAM2 | HEPACAM family member 2 | -20.0 |
| BMP2 | bone morphogenetic protein 2 | -20.0 |
| DPYSL3 | dihydropyrimidinase-like 3 | -20.0 |
| PLXNC1 | plexin C1 | -20.0 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -20.0 |
| RGS13 | regulator of G-protein signaling 13 | -20.0 |
| FGF7 | fibroblast growth factor 7 | -20.0 |
| GRASP | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein | -20.0 |
| GFI1B | growth factor independent 1B transcription repressor | -20.0 |
| PSD2 | pleckstrin and Sec7 domain containing 2 | -20.0 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -20.0 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -20.0 |
| PLA2G4D | phospholipase A2, group IVD (cytosolic) | -20.0 |
| ETV4 | ets variant 4 | -20.0 |
| CLSTN2 | calsyntenin 2 | -20.0 |
| CCM2L | cerebral cavernous malformation 2-like | -20.0 |
| MME | membrane metallo-endopeptidase | -20.0 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | -20.0 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | -20.0 |
| ALOX5 | arachidonate 5-lipoxygenase | -20.0 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | -20.0 |
| POU2F3 | POU class 2 homeobox 3 | -20.0 |
| CDH22 | cadherin 22, type 2 | -20.0 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -20.0 |
| C5ORF58 | chromosome 5 open reading frame 58 | -20.0 |
| CRYM | crystallin, mu | -20.0 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | -20.0 |
| RNMT | RNA (guanine-7-) methyltransferase | -20.0 |
| AVIL | advillin | -20.0 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -20.0 |
| PDZRN3 | PDZ domain containing ring finger 3 | -20.0 |
| RGS21 | regulator of G-protein signaling 21 | -19.699 |
| RNF144B | ring finger protein 144B | -19.5229 |
| C11ORF53 | chromosome 11 open reading frame 53 | -19.3979 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -19.0969 |
| SKAP2 | src kinase associated phosphoprotein 2 | -18.6778 |
| PALMD | palmdelphin | -18.3565 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -18.2924 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -17.8996 |
| MAP2 | microtubule-associated protein 2 | -17.8633 |
| MSTN | myostatin | -17.4634 |
| COL2A1 | collagen, type II, alpha 1 | -17.0017 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -16.5191 |
| CCDC129 | coiled-coil domain containing 129 | -16.1565 |
| B4GALNT2 | beta-1,4-N-acetyl-galactosaminyl transferase 2 | -15.9694 |
| TRIM58 | tripartite motif containing 58 | -15.6188 |
| PTPRT | protein tyrosine phosphatase, receptor type, T | -15.2748 |
| PROX1 | prospero homeobox 1 | -15.143 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -15.143 |
| CNKSR3 | CNKSR family member 3 | -14.1062 |
| DCHS2 | dachsous cadherin-related 2 | -14.0048 |
| RORB | RAR-related orphan receptor B | -13.7336 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -13.595 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) | -13.1201 |
| OTX2 | orthodenticle homeobox 2 | -13.0867 |
| IPO4 | importin 4 | -12.832 |
| NREP | neuronal regeneration related protein | -12.8019 |
| DLG2 | discs, large homolog 2 (Drosophila) | -12.6218 |
| PCDH19 | protocadherin 19 | -12.434 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -12.301 |
| LOX | lysyl oxidase | -12.2352 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -12.215 |
| PIR | pirin (iron-binding nuclear protein) | -11.8289 |
| ADGRB2 | adhesion G protein-coupled receptor B2 | -11.3721 |
| CCDC50 | coiled-coil domain containing 50 | -11.1954 |
| BMX | BMX non-receptor tyrosine kinase | -11.076 |
| INSM1 | insulinoma-associated 1 | -11.0683 |
| CHST9 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 | -11.009 |
| AASS | aminoadipate-semialdehyde synthase | -10.9171 |
| GRM4 | glutamate receptor, metabotropic 4 | -10.3102 |
| SLC22A23 | solute carrier family 22, member 23 | -10.1677 |
| DUSP4 | dual specificity phosphatase 4 | -9.79765 |
| CLIC5 | chloride intracellular channel 5 | -9.76429 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -9.63189 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -9.47537 |
| TSC1 | tuberous sclerosis 1 | -9.46875 |
| EPHA3 | EPH receptor A3 | -9.30019 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | -9.20903 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -9.19591 |
| ATG9B | autophagy related 9B | -9.10837 |
| STC2 | stanniocalcin 2 | -9.10172 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -8.9336 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -8.62722 |
| DCLK2 | doublecortin-like kinase 2 | -8.62644 |
| SERTAD4 | SERTA domain containing 4 | -8.57958 |
| SOX9 | SRY (sex determining region Y)-box 9 | -8.11029 |
| PHOSPHO1 | phosphatase, orphan 1 | -8.11029 |
| MTSS1 | metastasis suppressor 1 | -8.03086 |
| EFNB2 | ephrin-B2 | -8.0248 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain | -8.00014 |
| NCAM1 | neural cell adhesion molecule 1 | -7.77838 |
| EGFR | epidermal growth factor receptor | -7.75544 |
| ONECUT2 | one cut homeobox 2 | -7.72724 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | -7.41541 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 | -7.23135 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -7.05961 |
| TNIK | TRAF2 and NCK interacting kinase | -6.96039 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 | -6.88078 |
