| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting AJUBA in Sw480 cell line (Study accession: SRP253076) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_16970_KD_AJUBA_SRP253076 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PIWIL4 | piwi-like RNA-mediated gene silencing 4 | 13.2036 |
| NLRP12 | NLR family, pyrin domain containing 12 | 9.56729 |
| KCNT1 | potassium channel, sodium activated subfamily T, member 1 | 9.03291 |
| RGS7 | regulator of G-protein signaling 7 | 9.01433 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 6.31883 |
| T | T, brachyury homolog (mouse) | 6.02862 |
| MRPS34 | mitochondrial ribosomal protein S34 | 4.85748 |
| HFE | hemochromatosis | 4.65997 |
| GPR39 | G protein-coupled receptor 39 | 4.60481 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 4.60481 |
| TSPAN5 | tetraspanin 5 | 4.44754 |
| TMEM52B | transmembrane protein 52B | 3.97561 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 3.85713 |
| ADAMTSL4 | ADAMTS-like 4 | 3.56297 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | 3.54498 |
| MROH1 | maestro heat-like repeat family member 1 | 3.32222 |
| CABLES2 | Cdk5 and Abl enzyme substrate 2 | 3.22737 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 3.20806 |
| FZD4 | frizzled class receptor 4 | 3.12949 |
| RPS6KL1 | ribosomal protein S6 kinase-like 1 | 3.02684 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | 2.9736 |
| KRTAP4-16P | keratin associated protein 4-16, pseudogene | 2.81467 |
| CEP112 | centrosomal protein 112kDa | 2.77823 |
| WRAP73 | WD repeat containing, antisense to TP73 | 2.73638 |
| LONP1 | lon peptidase 1, mitochondrial | 2.70647 |
| ROM1 | retinal outer segment membrane protein 1 | 2.67504 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | 2.63652 |
| RNF167 | ring finger protein 167 | 2.6173 |
| PDZD4 | PDZ domain containing 4 | 2.60818 |
| CAMTA2 | calmodulin binding transcription activator 2 | 2.54542 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 2.51678 |
| MCPH1 | microcephalin 1 | 2.4364 |
| LCA5 | Leber congenital amaurosis 5 | 2.42737 |
| GALE | UDP-galactose-4-epimerase | 2.42737 |
| ST5 | suppression of tumorigenicity 5 | 2.37346 |
| PLEC | plectin | 2.35947 |
| VWA5B2 | von Willebrand factor A domain containing 5B2 | 2.30673 |
| HAGHL | hydroxyacylglutathione hydrolase-like | 2.30097 |
| MLF2 | myeloid leukemia factor 2 | 2.26532 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 2.26532 |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H | 2.25037 |
| MPPE1 | metallophosphoesterase 1 | 2.24594 |
| RGMA | repulsive guidance molecule family member a | 2.2394 |
| TMC8 | transmembrane channel-like 8 | 2.22732 |
| LEKR1 | leucine, glutamate and lysine rich 1 | 2.22204 |
| C16ORF93 | chromosome 16 open reading frame 93 | 2.20285 |
| SSTR5 | somatostatin receptor 5 | 2.20061 |
| CLIC3 | chloride intracellular channel 3 | 2.12819 |
| PTOV1 | prostate tumor overexpressed 1 | 2.12819 |
| MYO7B | myosin VIIB | 2.11217 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 2.04489 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | 2.03756 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 2.02562 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 2.00449 |
| FSCN2 | fascin actin-bundling protein 2, retinal | 1.9994 |
| KDM6B | lysine (K)-specific demethylase 6B | 1.9994 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 | 1.99083 |
| NUP62 | nucleoporin 62kDa | 1.94171 |
| ZIC5 | Zic family member 5 | 1.92003 |
| CFL1 | cofilin 1 (non-muscle) | 1.91267 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 1.91252 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 1.91109 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 1.90576 |
| PAM | peptidylglycine alpha-amidating monooxygenase | 1.88992 |
| SLC35F4 | solute carrier family 35, member F4 | 1.87715 |
| MINOS1 | mitochondrial inner membrane organizing system 1 | 1.87339 |
| AMOTL1 | angiomotin like 1 | 1.85602 |
| ADCK5 | aarF domain containing kinase 5 | 1.83928 |
| YIPF7 | Yip1 domain family, member 7 | 1.83508 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 1.82337 |
| CLDN19 | claudin 19 | 1.82337 |
| SV2C | synaptic vesicle glycoprotein 2C | 1.78803 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 1.7849 |
| RPL26L1 | ribosomal protein L26-like 1 | 1.78195 |
| RPL28 | ribosomal protein L28 | 1.77738 |
| ADGRD2 | adhesion G protein-coupled receptor D2 | 1.77738 |
| PARP10 | poly (ADP-ribose) polymerase family, member 10 | 1.77631 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 1.73032 |
| BRD9 | bromodomain containing 9 | 1.71325 |
| C12ORF49 | chromosome 12 open reading frame 49 | 1.704 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 1.704 |
| MED16 | mediator complex subunit 16 | 1.704 |
| SCTR | secretin receptor | 1.66994 |
| LRRC24 | leucine rich repeat containing 24 | 1.66644 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) | 1.64688 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 1.61491 |
| KLC1 | kinesin light chain 1 | 1.60576 |
| MAMDC4 | MAM domain containing 4 | 1.59717 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 1.58111 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 1.56562 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1.55467 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | 1.54423 |
| C3ORF56 | chromosome 3 open reading frame 56 | 1.53447 |
| TMCO6 | transmembrane and coiled-coil domains 6 | 1.53198 |
| SZT2 | seizure threshold 2 homolog (mouse) | 1.52535 |
| EVA1B | eva-1 homolog B (C. elegans) | 1.52476 |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | 1.51022 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 | 1.50717 |
| PEX6 | peroxisomal biogenesis factor 6 | 1.50446 |
| C1QTNF8 | C1q and tumor necrosis factor related protein 8 | 1.50413 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COLCA2 | colorectal cancer associated 2 | -20.0 |
| MVB12B | multivesicular body subunit 12B | -19.0458 |
| GPRIN1 | G protein regulated inducer of neurite outgrowth 1 | -14.2959 |
| FAM13C | family with sequence similarity 13, member C | -7.37612 |
| USP24 | ubiquitin specific peptidase 24 | -6.8668 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -6.65267 |
| MMP24-AS1 | MMP24 antisense RNA 1 | -6.46468 |
| USP37 | ubiquitin specific peptidase 37 | -6.43161 |
| GRIP2 | glutamate receptor interacting protein 2 | -5.40852 |
| ZSWIM7 | zinc finger, SWIM-type containing 7 | -5.22388 |
| C1ORF111 | chromosome 1 open reading frame 111 | -4.93497 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -4.7416 |
| VWA8 | von Willebrand factor A domain containing 8 | -4.73539 |
| RNF157 | ring finger protein 157 | -4.73539 |
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | -4.51196 |
| TSPAN11 | tetraspanin 11 | -4.47077 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -4.00677 |
| FGFR1 | fibroblast growth factor receptor 1 | -3.95181 |
| DTX1 | deltex 1, E3 ubiquitin ligase | -3.94003 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -3.47196 |
| CPLX2 | complexin 2 | -3.22751 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 | -3.14273 |
| PTBP3 | polypyrimidine tract binding protein 3 | -3.08885 |
| LETM2 | leucine zipper-EF-hand containing transmembrane protein 2 | -3.03283 |
| GAL3ST3 | galactose-3-O-sulfotransferase 3 | -2.9736 |
| CATSPER1 | cation channel, sperm associated 1 | -2.8506 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 | -2.69467 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -2.66346 |
| CLSTN2 | calsyntenin 2 | -2.585 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | -2.54765 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -2.51834 |
| MMRN2 | multimerin 2 | -2.45344 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -2.33064 |
| MLPH | melanophilin | -2.29719 |
| PCED1B | PC-esterase domain containing 1B | -2.25978 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -2.22975 |
| NUDCD2 | NudC domain containing 2 | -2.22225 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -2.10694 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -2.07508 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -2.04762 |
| MCOLN1 | mucolipin 1 | -1.94171 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -1.94171 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -1.85715 |
| LMOD1 | leiomodin 1 (smooth muscle) | -1.84876 |
| PYGL | phosphorylase, glycogen, liver | -1.84789 |
| THEM5 | thioesterase superfamily member 5 | -1.81271 |
| ENSA | endosulfine alpha | -1.79755 |
| CHMP1A | charged multivesicular body protein 1A | -1.79755 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | -1.79371 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -1.78803 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | -1.78306 |
| IGF1R | insulin-like growth factor 1 receptor | -1.77738 |
| LNPEP | leucyl/cystinyl aminopeptidase | -1.77631 |
| FLG2 | filaggrin family member 2 | -1.77493 |
| TRIM31 | tripartite motif containing 31 | -1.77493 |
| CRTAC1 | cartilage acidic protein 1 | -1.76585 |
| SESN3 | sestrin 3 | -1.76524 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -1.72686 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -1.70017 |
| ASPH | aspartate beta-hydroxylase | -1.68635 |
| GRPR | gastrin-releasing peptide receptor | -1.68635 |
| NGFR | nerve growth factor receptor | -1.68305 |
| RAB13 | RAB13, member RAS oncogene family | -1.66803 |
| KIF23 | kinesin family member 23 | -1.66496 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -1.66248 |
| BRD7 | bromodomain containing 7 | -1.65794 |
| KRT5 | keratin 5, type II | -1.63502 |
| PLCD1 | phospholipase C, delta 1 | -1.62365 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -1.62077 |
| SIGLEC16 | sialic acid binding Ig-like lectin 16 (gene/pseudogene) | -1.59717 |
| ARHGAP1 | Rho GTPase activating protein 1 | -1.57866 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | -1.57438 |
| PPP1R1B | protein phosphatase 1, regulatory (inhibitor) subunit 1B | -1.57282 |
| TMEM194B | transmembrane protein 194B | -1.56562 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -1.56562 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -1.55796 |
| LTA4H | leukotriene A4 hydrolase | -1.55211 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | -1.54866 |
| CACNA2D4 | calcium channel, voltage-dependent, alpha 2/delta subunit 4 | -1.53198 |
| TPT1 | tumor protein, translationally-controlled 1 | -1.52476 |
| TFRC | transferrin receptor | -1.50717 |
| GPI | glucose-6-phosphate isomerase | -1.50717 |
| ATP5SL | ATP5S-like | -1.50037 |
| H1F0 | H1 histone family, member 0 | -1.49052 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -1.46506 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -1.46317 |
| GPALPP1 | GPALPP motifs containing 1 | -1.46099 |
| GPR68 | G protein-coupled receptor 68 | -1.46099 |
| LBH | limb bud and heart development | -1.42158 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -1.40918 |
| ENO1 | enolase 1, (alpha) | -1.39957 |
| ITGAV | integrin, alpha V | -1.39957 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 | -1.37048 |
| TCF19 | transcription factor 19 | -1.3696 |
| HOXA10 | homeobox A10 | -1.36169 |
| LOC101929469 | uncharacterized protein ENSP00000372125 | -1.34278 |
| LOC441239 | uncharacterized LOC441239 | -1.34278 |
| CKAP2L | cytoskeleton associated protein 2-like | -1.34019 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -1.32662 |
| H2AFY | H2A histone family, member Y | -1.32628 |
