| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting CD248 in synovial sarcoma cell SJSA-1 tissue (Study accession: SRP402549) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_16980_KO_CD248_SRP402549 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SRFBP1 | serum response factor binding protein 1 | 17.5376 |
| CDC14B | cell division cycle 14B | 14.6893 |
| PHF10 | PHD finger protein 10 | 10.4165 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) | 9.8924 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 8.62959 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 8.32518 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 7.94278 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | 6.70991 |
| USP20 | ubiquitin specific peptidase 20 | 6.51413 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 6.21288 |
| MBNL1 | muscleblind-like splicing regulator 1 | 5.56911 |
| C5ORF45 | chromosome 5 open reading frame 45 | 5.06093 |
| HIST1H4I | histone cluster 1, H4i | 4.72398 |
| FSIP1 | fibrous sheath interacting protein 1 | 4.47884 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) | 4.3114 |
| NF1 | neurofibromin 1 | 3.90638 |
| JMJD8 | jumonji domain containing 8 | 3.89851 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta | 3.64949 |
| ANKRD37 | ankyrin repeat domain 37 | 3.35426 |
| IQCK | IQ motif containing K | 3.23539 |
| KCP | kielin/chordin-like protein | 3.1985 |
| TMEM79 | transmembrane protein 79 | 3.16903 |
| CEP63 | centrosomal protein 63kDa | 3.05237 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 2.99187 |
| AGBL5 | ATP/GTP binding protein-like 5 | 2.948 |
| FAM228B | family with sequence similarity 228, member B | 2.93805 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 2.93737 |
| FUZ | fuzzy planar cell polarity protein | 2.88737 |
| CNTD1 | cyclin N-terminal domain containing 1 | 2.8403 |
| CTNS | cystinosin, lysosomal cystine transporter | 2.7675 |
| KCTD2 | potassium channel tetramerization domain containing 2 | 2.74215 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 2.73913 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 2.70473 |
| MPC2 | mitochondrial pyruvate carrier 2 | 2.62106 |
| FGF2 | fibroblast growth factor 2 (basic) | 2.61675 |
| NUP62 | nucleoporin 62kDa | 2.47509 |
| ZNF655 | zinc finger protein 655 | 2.46196 |
| ZBTB21 | zinc finger and BTB domain containing 21 | 2.43579 |
| PLD4 | phospholipase D family, member 4 | 2.40145 |
| SNX24 | sorting nexin 24 | 2.39968 |
| C15ORF40 | chromosome 15 open reading frame 40 | 2.39477 |
| DOK4 | docking protein 4 | 2.33285 |
| FKBP15 | FK506 binding protein 15, 133kDa | 2.3079 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 2.3079 |
| LINC01183 | long intergenic non-protein coding RNA 1183 | 2.3079 |
| PGF | placental growth factor | 2.30163 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | 2.28876 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | 2.27186 |
| ZACN | zinc activated ligand-gated ion channel | 2.26098 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 2.25259 |
| HTRA1 | HtrA serine peptidase 1 | 2.24475 |
| YPEL4 | yippee-like 4 (Drosophila) | 2.24423 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 2.22955 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 2.21183 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | 2.20551 |
| CIITA | class II, major histocompatibility complex, transactivator | 2.19724 |
| TMEM262 | transmembrane protein 262 | 2.15999 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E | 2.12183 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | 2.09596 |
| TATDN1 | TatD DNase domain containing 1 | 2.09577 |
| C12ORF65 | chromosome 12 open reading frame 65 | 2.09408 |
| ZNF497 | zinc finger protein 497 | 2.08389 |
| CARD14 | caspase recruitment domain family, member 14 | 2.07279 |
| GFM2 | G elongation factor, mitochondrial 2 | 2.06502 |
| PKD2L2 | polycystic kidney disease 2-like 2 | 2.03715 |
| SNX22 | sorting nexin 22 | 2.03503 |
| CRMP1 | collapsin response mediator protein 1 | 2.03503 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 2.00183 |
| TOR3A | torsin family 3, member A | 1.98091 |
| PROX2 | prospero homeobox 2 | 1.97838 |
| CCDC151 | coiled-coil domain containing 151 | 1.96834 |
| SNAP47 | synaptosomal-associated protein, 47kDa | 1.96013 |
| CUX2 | cut-like homeobox 2 | 1.94494 |
| MYO7B | myosin VIIB | 1.9324 |
| ZNF263 | zinc finger protein 263 | 1.92886 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 1.92344 |
| ARL10 | ADP-ribosylation factor-like 10 | 1.91981 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 1.91063 |
| GOLGA4 | golgin A4 | 1.88386 |
| SIK2 | salt-inducible kinase 2 | 1.85405 |
| TMEM198 | transmembrane protein 198 | 1.84136 |
| TTC39A | tetratricopeptide repeat domain 39A | 1.84003 |
| JMJD1C | jumonji domain containing 1C | 1.83497 |
| POLR3H | polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) | 1.83363 |
| LINC00854 | long intergenic non-protein coding RNA 854 | 1.82394 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 1.82026 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 1.79753 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 1.79753 |
| SLA2 | Src-like-adaptor 2 | 1.7899 |
| HFE | hemochromatosis | 1.78122 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 1.77956 |
| TMEM97 | transmembrane protein 97 | 1.77666 |
| A1BG | alpha-1-B glycoprotein | 1.76297 |
| NUP88 | nucleoporin 88kDa | 1.73079 |
| BCL7A | B-cell CLL/lymphoma 7A | 1.73079 |
| MICA | MHC class I polypeptide-related sequence A | 1.72591 |
| SGCE | sarcoglycan, epsilon | 1.72352 |
| C17ORF104 | chromosome 17 open reading frame 104 | 1.70692 |
| NALCN | sodium leak channel, non selective | 1.70431 |
| C14ORF93 | chromosome 14 open reading frame 93 | 1.69654 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 | -18.4949 |
| DISP2 | dispatched homolog 2 (Drosophila) | -9.89441 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -9.62987 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | -9.36489 |
| L3MBTL2 | l(3)mbt-like 2 (Drosophila) | -9.34704 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | -9.252 |
| BLM | Bloom syndrome, RecQ helicase-like | -8.04598 |
| HDLBP | high density lipoprotein binding protein | -7.21501 |
| GLYCTK | glycerate kinase | -6.62779 |
| ADRM1 | adhesion regulating molecule 1 | -6.21288 |
| MPPE1 | metallophosphoesterase 1 | -5.7466 |
| PRCD | progressive rod-cone degeneration | -5.51489 |
| SLC51B | solute carrier family 51, beta subunit | -5.31188 |
| TRIM37 | tripartite motif containing 37 | -5.15137 |
| KIAA0895 | KIAA0895 | -5.13722 |
| CCDC85B | coiled-coil domain containing 85B | -5.04058 |
| GRK5 | G protein-coupled receptor kinase 5 | -4.93288 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | -4.64042 |
| SCLT1 | sodium channel and clathrin linker 1 | -4.58211 |
| INHBC | inhibin, beta C | -4.44702 |
| TYRP1 | tyrosinase-related protein 1 | -4.37529 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -4.3114 |
| ZNF276 | zinc finger protein 276 | -4.19889 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -4.07899 |
| FAM149B1 | family with sequence similarity 149, member B1 | -3.92423 |
| ATP5H | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d | -3.88595 |
| RAP1GAP | RAP1 GTPase activating protein | -3.85895 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | -3.80084 |
| STK17A | serine/threonine kinase 17a | -3.73096 |
| WBSCR22 | Williams Beuren syndrome chromosome region 22 | -3.71409 |
| CSNK1D | casein kinase 1, delta | -3.68075 |
| PTOV1 | prostate tumor overexpressed 1 | -3.47814 |
| BRD7 | bromodomain containing 7 | -3.443 |
| DDIT3 | DNA-damage-inducible transcript 3 | -3.42394 |
| RHOC | ras homolog family member C | -3.42189 |
| CDC42SE1 | CDC42 small effector 1 | -3.2376 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -3.15842 |
| C8ORF59 | chromosome 8 open reading frame 59 | -2.97303 |
| TMEM258 | transmembrane protein 258 | -2.96926 |
| INHBE | inhibin, beta E | -2.9578 |
| PAQR3 | progestin and adipoQ receptor family member III | -2.948 |
| ATXN2 | ataxin 2 | -2.90769 |
| ANGPT4 | angiopoietin 4 | -2.73568 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | -2.73568 |
| HPS4 | Hermansky-Pudlak syndrome 4 | -2.67451 |
| COL1A1 | collagen, type I, alpha 1 | -2.62693 |
| MRPL51 | mitochondrial ribosomal protein L51 | -2.61308 |
| H1FX | H1 histone family, member X | -2.61308 |
| C11ORF68 | chromosome 11 open reading frame 68 | -2.51134 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) | -2.47802 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -2.40145 |
| C3ORF17 | chromosome 3 open reading frame 17 | -2.39477 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -2.25259 |
| MRPS25 | mitochondrial ribosomal protein S25 | -2.21986 |
| POLH | polymerase (DNA directed), eta | -2.15999 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | -2.14748 |
| RANGRF | RAN guanine nucleotide release factor | -2.13431 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 | -2.11872 |
| TUBA4A | tubulin, alpha 4a | -2.09577 |
| COX20 | COX20 cytochrome c oxidase assembly factor | -2.09577 |
| STAC3 | SH3 and cysteine rich domain 3 | -2.05517 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.05282 |
| NCOA4 | nuclear receptor coactivator 4 | -2.04756 |
| TREH | trehalase (brush-border membrane glycoprotein) | -2.01957 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | -1.99557 |
| IRS1 | insulin receptor substrate 1 | -1.98091 |
| KLK2 | kallikrein-related peptidase 2 | -1.96834 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -1.92515 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -1.91063 |
| GLI1 | GLI family zinc finger 1 | -1.90975 |
| ENOSF1 | enolase superfamily member 1 | -1.90014 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -1.88441 |
| ABI2 | abl-interactor 2 | -1.84003 |
| HOOK2 | hook microtubule-tethering protein 2 | -1.82026 |
| DDHD2 | DDHD domain containing 2 | -1.81415 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -1.81415 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -1.81415 |
| ILVBL | ilvB (bacterial acetolactate synthase)-like | -1.79352 |
| LOC122455342 | testis-specific serine/proline-rich protein | -1.77775 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | -1.76297 |
| OGG1 | 8-oxoguanine DNA glycosylase | -1.75387 |
| ORAOV1 | oral cancer overexpressed 1 | -1.74744 |
| SKP1 | S-phase kinase-associated protein 1 | -1.73079 |
| MARS | methionyl-tRNA synthetase | -1.73079 |
| AP3M1 | adaptor-related protein complex 3, mu 1 subunit | -1.73034 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -1.72352 |
| IGSF10 | immunoglobulin superfamily, member 10 | -1.72352 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -1.72352 |
| ELN | elastin | -1.7009 |
| MTERF4 | mitochondrial transcription termination factor 4 | -1.69537 |
| C7ORF49 | chromosome 7 open reading frame 49 | -1.67377 |
| FAM160B2 | family with sequence similarity 160, member B2 | -1.65461 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 | -1.64514 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | -1.64514 |
| GSE1 | Gse1 coiled-coil protein | -1.64261 |
| CENPO | centromere protein O | -1.63758 |
| KLC1 | kinesin light chain 1 | -1.61981 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -1.59889 |
| CBX1 | chromobox homolog 1 | -1.59889 |
| MAX | MYC associated factor X | -1.57965 |
