| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting HER2 in T47D cell line (Study accession: SRP166112) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_17188_OE_HER2_SRP166112 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EI24 | etoposide induced 2.4 | 20.0 |
| GBA | glucosidase, beta, acid | 20.0 |
| SDCBP | syndecan binding protein (syntenin) | 20.0 |
| HEXB | hexosaminidase B (beta polypeptide) | 20.0 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 20.0 |
| SFXN3 | sideroflexin 3 | 20.0 |
| SNX8 | sorting nexin 8 | 20.0 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 20.0 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 | 20.0 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 20.0 |
| SQSTM1 | sequestosome 1 | 20.0 |
| G6PD | glucose-6-phosphate dehydrogenase | 20.0 |
| SRP68 | signal recognition particle 68kDa | 20.0 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 20.0 |
| MAF1 | MAF1 homolog (S. cerevisiae) | 20.0 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 20.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | 20.0 |
| TRIB3 | tribbles pseudokinase 3 | 20.0 |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 20.0 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 20.0 |
| CDK16 | cyclin-dependent kinase 16 | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| STX3 | syntaxin 3 | 20.0 |
| INSIG1 | insulin induced gene 1 | 20.0 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 20.0 |
| SCARB2 | scavenger receptor class B, member 2 | 20.0 |
| CST3 | cystatin C | 20.0 |
| MFSD5 | major facilitator superfamily domain containing 5 | 20.0 |
| LY6E | lymphocyte antigen 6 complex, locus E | 20.0 |
| TMEM40 | transmembrane protein 40 | 20.0 |
| SEPHS2 | selenophosphate synthetase 2 | 20.0 |
| RPS2 | ribosomal protein S2 | 20.0 |
| HS1BP3 | HCLS1 binding protein 3 | 20.0 |
| AHNAK2 | AHNAK nucleoprotein 2 | 20.0 |
| CAPN2 | calpain 2, (m/II) large subunit | 20.0 |
| GM2A | GM2 ganglioside activator | 20.0 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 20.0 |
| DHCR7 | 7-dehydrocholesterol reductase | 20.0 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 20.0 |
| VPS18 | vacuolar protein sorting 18 homolog (S. cerevisiae) | 20.0 |
| PKP3 | plakophilin 3 | 20.0 |
| MTDH | metadherin | 20.0 |
| MVD | mevalonate (diphospho) decarboxylase | 20.0 |
| RNF10 | ring finger protein 10 | 20.0 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 20.0 |
| TMEM97 | transmembrane protein 97 | 20.0 |
| PPP4C | protein phosphatase 4, catalytic subunit | 20.0 |
| MSMO1 | methylsterol monooxygenase 1 | 20.0 |
| TMEM38B | transmembrane protein 38B | 20.0 |
| HPS1 | Hermansky-Pudlak syndrome 1 | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| CTSA | cathepsin A | 20.0 |
| CTSF | cathepsin F | 20.0 |
| WBP2 | WW domain binding protein 2 | 20.0 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 | 20.0 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 20.0 |
| PFKP | phosphofructokinase, platelet | 20.0 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 20.0 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 20.0 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 20.0 |
| PRSS8 | protease, serine, 8 | 20.0 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 20.0 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 20.0 |
| ERO1L | ERO1-like (S. cerevisiae) | 20.0 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 20.0 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 20.0 |
| MTCH1 | mitochondrial carrier 1 | 20.0 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 20.0 |
| OPTN | optineurin | 20.0 |
| ZDHHC3 | zinc finger, DHHC-type containing 3 | 20.0 |
| ACTN1 | actinin, alpha 1 | 20.0 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 20.0 |
| FAM102A | family with sequence similarity 102, member A | 20.0 |
| SLC38A7 | solute carrier family 38, member 7 | 20.0 |
| FTH1 | ferritin, heavy polypeptide 1 | 20.0 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 20.0 |
| FAM213A | family with sequence similarity 213, member A | 20.0 |
| SQLE | squalene epoxidase | 20.0 |
| GPNMB | glycoprotein (transmembrane) nmb | 20.0 |
| GUCD1 | guanylyl cyclase domain containing 1 | 20.0 |
| GLMP | glycosylated lysosomal membrane protein | 20.0 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 20.0 |
| C6ORF1 | chromosome 6 open reading frame 1 | 20.0 |
| AMDHD2 | amidohydrolase domain containing 2 | 20.0 |
| GRSF1 | G-rich RNA sequence binding factor 1 | 20.0 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | 20.0 |
| PKM | pyruvate kinase, muscle | 20.0 |
| STARD10 | StAR-related lipid transfer (START) domain containing 10 | 20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 20.0 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 20.0 |
| TSKU | tsukushi, small leucine rich proteoglycan | 20.0 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 20.0 |
| PEG10 | paternally expressed 10 | 20.0 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 20.0 |
| APOD | apolipoprotein D | 20.0 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 | 20.0 |
| RORC | RAR-related orphan receptor C | 20.0 |
| HMOX1 | heme oxygenase 1 | 20.0 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 20.0 |
| RAB7A | RAB7A, member RAS oncogene family | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARL4D | ADP-ribosylation factor-like 4D | -20.0 |
| PRLR | prolactin receptor | -20.0 |
| ZNF552 | zinc finger protein 552 | -20.0 |
| KIAA1161 | KIAA1161 | -20.0 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -20.0 |
| HIST1H2BG | histone cluster 1, H2bg | -20.0 |
| TGFB3 | transforming growth factor, beta 3 | -20.0 |
| TOB1 | transducer of ERBB2, 1 | -20.0 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -20.0 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | -20.0 |
| TNS3 | tensin 3 | -20.0 |
| STC2 | stanniocalcin 2 | -20.0 |
| MAGED1 | melanoma antigen family D1 | -20.0 |
| SELENBP1 | selenium binding protein 1 | -20.0 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -20.0 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -20.0 |
| SPDEF | SAM pointed domain containing ETS transcription factor | -20.0 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -20.0 |
| CYBRD1 | cytochrome b reductase 1 | -20.0 |
| TENM3 | teneurin transmembrane protein 3 | -20.0 |
| TMC4 | transmembrane channel-like 4 | -20.0 |
| FN1 | fibronectin 1 | -20.0 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | -20.0 |
| KRT23 | keratin 23, type I | -20.0 |
| CPAMD8 | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 | -20.0 |
| PPM1K | protein phosphatase, Mg2+/Mn2+ dependent, 1K | -20.0 |
| PALLD | palladin, cytoskeletal associated protein | -20.0 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -20.0 |
| THBS1 | thrombospondin 1 | -20.0 |
| ADD3 | adducin 3 (gamma) | -20.0 |
| SUOX | sulfite oxidase | -20.0 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -20.0 |
| CADM1 | cell adhesion molecule 1 | -20.0 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -20.0 |
| RPL17 | ribosomal protein L17 | -20.0 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -20.0 |
| GAA | glucosidase, alpha; acid | -20.0 |
| HIST1H2AC | histone cluster 1, H2ac | -20.0 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -20.0 |
| BNIPL | BCL2/adenovirus E1B 19kD interacting protein like | -20.0 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | -20.0 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -20.0 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -20.0 |
| LIPC | lipase, hepatic | -20.0 |
| CLDN1 | claudin 1 | -20.0 |
| SATB1 | SATB homeobox 1 | -20.0 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -20.0 |
| PHACTR1 | phosphatase and actin regulator 1 | -20.0 |
| PIP | prolactin-induced protein | -20.0 |
| IGSF3 | immunoglobulin superfamily, member 3 | -20.0 |
| MFSD10 | major facilitator superfamily domain containing 10 | -20.0 |
| SLC22A23 | solute carrier family 22, member 23 | -20.0 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | -20.0 |
| WDR6 | WD repeat domain 6 | -20.0 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -20.0 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -20.0 |
| KIAA1324 | KIAA1324 | -20.0 |
| PHGDH | phosphoglycerate dehydrogenase | -20.0 |
| PGR | progesterone receptor | -20.0 |
| CISH | cytokine inducible SH2-containing protein | -20.0 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -20.0 |
| CCDC170 | coiled-coil domain containing 170 | -20.0 |
| CCNA2 | cyclin A2 | -20.0 |
| LAMB2 | laminin, beta 2 (laminin S) | -20.0 |
| BCL6 | B-cell CLL/lymphoma 6 | -20.0 |
| LOC105375355 | uroplakin-3b | -20.0 |
| STOM | stomatin | -20.0 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -20.0 |
| UPK2 | uroplakin 2 | -20.0 |
| GNMT | glycine N-methyltransferase | -20.0 |
| TCTN1 | tectonic family member 1 | -20.0 |
| EHF | ets homologous factor | -20.0 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -20.0 |
| CSAD | cysteine sulfinic acid decarboxylase | -20.0 |
| ACTB | actin, beta | -20.0 |
| PXK | PX domain containing serine/threonine kinase | -20.0 |
| FGF12 | fibroblast growth factor 12 | -20.0 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -20.0 |
| BCAS1 | breast carcinoma amplified sequence 1 | -20.0 |
| CCNO | cyclin O | -20.0 |
| TMPRSS13 | transmembrane protease, serine 13 | -20.0 |
| COL12A1 | collagen, type XII, alpha 1 | -20.0 |
| SIAE | sialic acid acetylesterase | -20.0 |
| CLK3 | CDC-like kinase 3 | -20.0 |
| KRT19 | keratin 19, type I | -20.0 |
| CERS2 | ceramide synthase 2 | -20.0 |
| EDN1 | endothelin 1 | -20.0 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | -20.0 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -20.0 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | -20.0 |
| KRT15 | keratin 15, type I | -20.0 |
| SLC40A1 | solute carrier family 40 (iron-regulated transporter), member 1 | -20.0 |
| CAB39L | calcium binding protein 39-like | -19.699 |
| MAP1A | microtubule-associated protein 1A | -19.699 |
| FSTL1 | follistatin-like 1 | -19.699 |
| IL1R1 | interleukin 1 receptor, type I | -19.301 |
| PLXNB1 | plexin B1 | -19.1549 |
| C9ORF3 | chromosome 9 open reading frame 3 | -19.0458 |
| BTD | biotinidase | -18.9208 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | -18.8861 |
