| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting HER2 in T47D cell line (Study accession: SRP166112) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_17198_OE_HER2_SRP166112 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FXYD5 | FXYD domain containing ion transport regulator 5 | 20.0 |
| TPM1 | tropomyosin 1 (alpha) | 20.0 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 20.0 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 20.0 |
| SDCBP | syndecan binding protein (syntenin) | 20.0 |
| SFXN1 | sideroflexin 1 | 20.0 |
| ASPH | aspartate beta-hydroxylase | 20.0 |
| PKP3 | plakophilin 3 | 20.0 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 20.0 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 20.0 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 20.0 |
| SHISA5 | shisa family member 5 | 20.0 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 20.0 |
| CD63 | CD63 molecule | 20.0 |
| SDC1 | syndecan 1 | 20.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | 20.0 |
| TRIB3 | tribbles pseudokinase 3 | 20.0 |
| OSMR | oncostatin M receptor | 20.0 |
| SURF4 | surfeit 4 | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| S100A9 | S100 calcium binding protein A9 | 20.0 |
| IFI6 | interferon, alpha-inducible protein 6 | 20.0 |
| PLK2 | polo-like kinase 2 | 20.0 |
| MX1 | MX dynamin-like GTPase 1 | 20.0 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 20.0 |
| IFITM2 | interferon induced transmembrane protein 2 | 20.0 |
| CCND3 | cyclin D3 | 20.0 |
| BST2 | bone marrow stromal cell antigen 2 | 20.0 |
| LY6E | lymphocyte antigen 6 complex, locus E | 20.0 |
| OCLN | occludin | 20.0 |
| TSPAN1 | tetraspanin 1 | 20.0 |
| TMEM40 | transmembrane protein 40 | 20.0 |
| ABCC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 11 | 20.0 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 20.0 |
| ACER3 | alkaline ceramidase 3 | 20.0 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 20.0 |
| CCND1 | cyclin D1 | 20.0 |
| TXNRD1 | thioredoxin reductase 1 | 20.0 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 20.0 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 20.0 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 20.0 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 20.0 |
| DAP | death-associated protein | 20.0 |
| CD44 | CD44 molecule (Indian blood group) | 20.0 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 20.0 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 20.0 |
| S100P | S100 calcium binding protein P | 20.0 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 20.0 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 20.0 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 20.0 |
| PFKP | phosphofructokinase, platelet | 20.0 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 20.0 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 20.0 |
| PRSS8 | protease, serine, 8 | 20.0 |
| FHL2 | four and a half LIM domains 2 | 20.0 |
| S100A16 | S100 calcium binding protein A16 | 20.0 |
| TSKU | tsukushi, small leucine rich proteoglycan | 20.0 |
| ESRP1 | epithelial splicing regulatory protein 1 | 20.0 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 20.0 |
| TXNIP | thioredoxin interacting protein | 20.0 |
| WDR1 | WD repeat domain 1 | 20.0 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 20.0 |
| COMT | catechol-O-methyltransferase | 20.0 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 20.0 |
| HLA-B | major histocompatibility complex, class I, B | 20.0 |
| ACTN1 | actinin, alpha 1 | 20.0 |
| EZR | ezrin | 20.0 |
| TSPAN15 | tetraspanin 15 | 20.0 |
| ERO1L | ERO1-like (S. cerevisiae) | 20.0 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 20.0 |
| RRM2 | ribonucleotide reductase M2 | 20.0 |
| UGDH | UDP-glucose 6-dehydrogenase | 20.0 |
| PVR | poliovirus receptor | 20.0 |
| KRT7 | keratin 7, type II | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| SDSL | serine dehydratase-like | 20.0 |
| GRSF1 | G-rich RNA sequence binding factor 1 | 20.0 |
| ANXA1 | annexin A1 | 20.0 |
| MST1R | macrophage stimulating 1 receptor | 20.0 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 20.0 |
| CDCP1 | CUB domain containing protein 1 | 20.0 |
| PXDN | peroxidasin | 20.0 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 20.0 |
| LMCD1 | LIM and cysteine-rich domains 1 | 20.0 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 20.0 |
| CDC25B | cell division cycle 25B | 20.0 |
| TMEM45B | transmembrane protein 45B | 20.0 |
| PPL | periplakin | 20.0 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 20.0 |
| CCDC6 | coiled-coil domain containing 6 | 20.0 |
| KRT18 | keratin 18, type I | 20.0 |
| PRNP | prion protein | 20.0 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | 20.0 |
| AGR2 | anterior gradient 2 | 20.0 |
| PRAME | preferentially expressed antigen in melanoma | 20.0 |
| HLA-C | major histocompatibility complex, class I, C | 20.0 |
| HLA-E | major histocompatibility complex, class I, E | 20.0 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 20.0 |
| AREG | amphiregulin | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CAB39L | calcium binding protein 39-like | -20.0 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -20.0 |
| NINJ1 | ninjurin 1 | -20.0 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -20.0 |
| GSTM4 | glutathione S-transferase mu 4 | -20.0 |
| HSPB11 | heat shock protein family B (small), member 11 | -20.0 |
| KRT23 | keratin 23, type I | -20.0 |
| C9ORF3 | chromosome 9 open reading frame 3 | -20.0 |
| FTO | fat mass and obesity associated | -20.0 |
| METTL7A | methyltransferase like 7A | -20.0 |
| AIG1 | androgen-induced 1 | -20.0 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | -20.0 |
| NNT | nicotinamide nucleotide transhydrogenase | -20.0 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -20.0 |
| TENM3 | teneurin transmembrane protein 3 | -20.0 |
| TENM2 | teneurin transmembrane protein 2 | -20.0 |
| CORO2A | coronin, actin binding protein, 2A | -20.0 |
| SLC39A11 | solute carrier family 39, member 11 | -20.0 |
| TTC3 | tetratricopeptide repeat domain 3 | -20.0 |
| PHPT1 | phosphohistidine phosphatase 1 | -20.0 |
| FN1 | fibronectin 1 | -20.0 |
| KIF20A | kinesin family member 20A | -20.0 |
| SFXN2 | sideroflexin 2 | -20.0 |
| CMBL | carboxymethylenebutenolidase homolog (Pseudomonas) | -20.0 |
| SYBU | syntabulin (syntaxin-interacting) | -20.0 |
| BTD | biotinidase | -20.0 |
| ESR1 | estrogen receptor 1 | -20.0 |
| PPM1K | protein phosphatase, Mg2+/Mn2+ dependent, 1K | -20.0 |
| IL1R1 | interleukin 1 receptor, type I | -20.0 |
| PALLD | palladin, cytoskeletal associated protein | -20.0 |
| SOAT1 | sterol O-acyltransferase 1 | -20.0 |
| PCP4L1 | Purkinje cell protein 4 like 1 | -20.0 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -20.0 |
| CADM1 | cell adhesion molecule 1 | -20.0 |
| SATB1 | SATB homeobox 1 | -20.0 |
| CDV3 | CDV3 homolog (mouse) | -20.0 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -20.0 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -20.0 |
| GLA | galactosidase, alpha | -20.0 |
| PTGES | prostaglandin E synthase | -20.0 |
| BNIPL | BCL2/adenovirus E1B 19kD interacting protein like | -20.0 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -20.0 |
| SEPT8 | septin 8 | -20.0 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -20.0 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -20.0 |
| NDRG2 | NDRG family member 2 | -20.0 |
| BLMH | bleomycin hydrolase | -20.0 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -20.0 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -20.0 |
| GPX4 | glutathione peroxidase 4 | -20.0 |
| PHACTR1 | phosphatase and actin regulator 1 | -20.0 |
| PIR | pirin (iron-binding nuclear protein) | -20.0 |
| THYN1 | thymocyte nuclear protein 1 | -20.0 |
| MTUS1 | microtubule associated tumor suppressor 1 | -20.0 |
| SLC22A23 | solute carrier family 22, member 23 | -20.0 |
| LTA4H | leukotriene A4 hydrolase | -20.0 |
| XG | Xg blood group | -20.0 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -20.0 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -20.0 |
| OLFML3 | olfactomedin-like 3 | -20.0 |
| PHGDH | phosphoglycerate dehydrogenase | -20.0 |
| FANCA | Fanconi anemia, complementation group A | -20.0 |
| PGR | progesterone receptor | -20.0 |
| GNMT | glycine N-methyltransferase | -20.0 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -20.0 |
| MB | myoglobin | -20.0 |
| MAP1A | microtubule-associated protein 1A | -20.0 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -20.0 |
| BCL6 | B-cell CLL/lymphoma 6 | -20.0 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -20.0 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -20.0 |
| C9ORF116 | chromosome 9 open reading frame 116 | -20.0 |
| TPD52L1 | tumor protein D52-like 1 | -20.0 |
| LOC105375355 | uroplakin-3b | -20.0 |
| TCTN1 | tectonic family member 1 | -20.0 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -20.0 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -20.0 |
| COL12A1 | collagen, type XII, alpha 1 | -20.0 |
| ANXA9 | annexin A9 | -20.0 |
| CDC20 | cell division cycle 20 | -20.0 |
| SIAE | sialic acid acetylesterase | -20.0 |
| ARL4D | ADP-ribosylation factor-like 4D | -20.0 |
| SELENBP1 | selenium binding protein 1 | -20.0 |
| PXK | PX domain containing serine/threonine kinase | -20.0 |
| PLCE1 | phospholipase C, epsilon 1 | -20.0 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -20.0 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | -20.0 |
| BCAS1 | breast carcinoma amplified sequence 1 | -20.0 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | -20.0 |
| EHF | ets homologous factor | -20.0 |
| SEPP1 | selenoprotein P, plasma, 1 | -20.0 |
| TCEA3 | transcription elongation factor A (SII), 3 | -20.0 |
| BRD8 | bromodomain containing 8 | -20.0 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -20.0 |
| CSAD | cysteine sulfinic acid decarboxylase | -20.0 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -20.0 |
| SCPEP1 | serine carboxypeptidase 1 | -20.0 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -20.0 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -20.0 |
| CENPF | centromere protein F, 350/400kDa | -20.0 |
