| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting GATA3|JUN in T47D cell line (Study accession: SRP188712) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_17201_OE_GATA3|JUN_SRP188712 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBN1 | ubinuclein 1 | 20.0 |
| C12ORF73 | chromosome 12 open reading frame 73 | 20.0 |
| ANGPTL6 | angiopoietin-like 6 | 20.0 |
| C5ORF45 | chromosome 5 open reading frame 45 | 20.0 |
| TMEM184A | transmembrane protein 184A | 20.0 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 20.0 |
| TLDC2 | TBC/LysM-associated domain containing 2 | 20.0 |
| WDR86 | WD repeat domain 86 | 20.0 |
| C7ORF49 | chromosome 7 open reading frame 49 | 20.0 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 | 20.0 |
| THAP11 | THAP domain containing 11 | 20.0 |
| ABI2 | abl-interactor 2 | 20.0 |
| ACO1 | aconitase 1, soluble | 20.0 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | 18.699 |
| BEST1 | bestrophin 1 | 18.2366 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 18.2147 |
| GPR137 | G protein-coupled receptor 137 | 14.6505 |
| SUN2 | Sad1 and UNC84 domain containing 2 | 13.7183 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | 12.0543 |
| CDH13 | cadherin 13 | 11.1317 |
| RRBP1 | ribosome binding protein 1 | 11.0243 |
| GPR39 | G protein-coupled receptor 39 | 10.9702 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | 10.7526 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 9.84405 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | 8.88615 |
| GPR132 | G protein-coupled receptor 132 | 8.8784 |
| JUN | jun proto-oncogene | 8.76239 |
| TRRAP | transformation/transcription domain-associated protein | 8.69055 |
| GLS | glutaminase | 8.57375 |
| NKIRAS1 | NFKB inhibitor interacting Ras-like 1 | 8.03257 |
| COG5 | component of oligomeric golgi complex 5 | 7.99176 |
| MARS | methionyl-tRNA synthetase | 7.7747 |
| PAQR3 | progestin and adipoQ receptor family member III | 7.01996 |
| CLVS1 | clavesin 1 | 6.39578 |
| IFIH1 | interferon induced with helicase C domain 1 | 6.07641 |
| MYCBP | MYC binding protein | 5.93756 |
| RPS27A | ribosomal protein S27a | 5.87404 |
| OGFR | opioid growth factor receptor | 5.70278 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 5.29496 |
| WBSCR22 | Williams Beuren syndrome chromosome region 22 | 5.29404 |
| CTNS | cystinosin, lysosomal cystine transporter | 5.10338 |
| PERM1 | PPARGC1 and ESRR induced regulator, muscle 1 | 5.07057 |
| TRIM31 | tripartite motif containing 31 | 5.04497 |
| TRABD2A | TraB domain containing 2A | 4.90005 |
| TPBG | trophoblast glycoprotein | 4.87445 |
| NANS | N-acetylneuraminic acid synthase | 4.76019 |
| ACOT13 | acyl-CoA thioesterase 13 | 4.65294 |
| HEATR1 | HEAT repeat containing 1 | 4.51476 |
| CAST | calpastatin | 4.32009 |
| LOXL3 | lysyl oxidase-like 3 | 4.21248 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 | 4.06681 |
| C18ORF8 | chromosome 18 open reading frame 8 | 4.04376 |
| RHOC | ras homolog family member C | 4.00165 |
| MIEN1 | migration and invasion enhancer 1 | 3.99406 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 3.94111 |
| XRRA1 | X-ray radiation resistance associated 1 | 3.86545 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | 3.65275 |
| EMC9 | ER membrane protein complex subunit 9 | 3.5452 |
| TTC6 | tetratricopeptide repeat domain 6 | 3.51127 |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 3.50891 |
| BRI3 | brain protein I3 | 3.45251 |
| TRIM56 | tripartite motif containing 56 | 3.42436 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 3.2735 |
| THRA | thyroid hormone receptor, alpha | 3.24505 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 3.20586 |
| EPHA1 | EPH receptor A1 | 3.19063 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 3.16754 |
| KRT80 | keratin 80, type II | 3.1515 |
| OTUD7B | OTU deubiquitinase 7B | 3.13399 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 3.09211 |
| UPK2 | uroplakin 2 | 2.98441 |
| NUP62 | nucleoporin 62kDa | 2.95206 |
| SAMHD1 | SAM domain and HD domain 1 | 2.84228 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 2.82923 |
| MYBBP1A | MYB binding protein (P160) 1a | 2.82834 |
| LAMTOR4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | 2.82633 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 2.82218 |
| KRTAP5-8 | keratin associated protein 5-8 | 2.78401 |
| SPAG1 | sperm associated antigen 1 | 2.78401 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 2.78024 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 2.71566 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 2.69655 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 2.68419 |
| PKM | pyruvate kinase, muscle | 2.67953 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa | 2.62279 |
| MROH8 | maestro heat-like repeat family member 8 | 2.50244 |
| C1ORF54 | chromosome 1 open reading frame 54 | 2.50026 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 2.43833 |
| RAB43 | RAB43, member RAS oncogene family | 2.38318 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 2.37671 |
| ADAM9 | ADAM metallopeptidase domain 9 | 2.34168 |
| DSP | desmoplakin | 2.23749 |
| IL16 | interleukin 16 | 2.233 |
| SDC4 | syndecan 4 | 2.233 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 2.22448 |
| KIAA2018 | KIAA2018 | 2.22423 |
| FSIP1 | fibrous sheath interacting protein 1 | 2.1689 |
| TMEM132A | transmembrane protein 132A | 2.05531 |
| RSPH9 | radial spoke head 9 homolog (Chlamydomonas) | 2.0317 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 2.0244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | -20.0 |
| BBIP1 | BBSome interacting protein 1 | -20.0 |
| LRRC75A | leucine rich repeat containing 75A | -20.0 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -15.5142 |
| FAM120AOS | family with sequence similarity 120A opposite strand | -14.5241 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | -13.946 |
| ZNHIT2 | zinc finger, HIT-type containing 2 | -11.2784 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -10.3997 |
| ARG2 | arginase 2 | -8.52975 |
| TAPBP | TAP binding protein (tapasin) | -8.39399 |
| PAH | phenylalanine hydroxylase | -8.26405 |
| ATG10 | autophagy related 10 | -7.93645 |
| CFAP126 | cilia and flagella associated protein 126 | -7.84701 |
| ZNF497 | zinc finger protein 497 | -7.6502 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | -7.51539 |
| FOXH1 | forkhead box H1 | -7.2446 |
| TMPRSS4 | transmembrane protease, serine 4 | -7.20036 |
| RABL6 | RAB, member RAS oncogene family-like 6 | -6.82585 |
| CLCC1 | chloride channel CLIC-like 1 | -6.68042 |
| TRIM59 | tripartite motif containing 59 | -6.60228 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -6.44966 |
| EIF4B | eukaryotic translation initiation factor 4B | -6.17471 |
| ZBTB45 | zinc finger and BTB domain containing 45 | -6.0054 |
| STK24 | serine/threonine kinase 24 | -5.96736 |
| IL18BP | interleukin 18 binding protein | -5.59587 |
| ACBD6 | acyl-CoA binding domain containing 6 | -5.29774 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -5.0763 |
| HDDC2 | HD domain containing 2 | -4.54123 |
| C9ORF172 | chromosome 9 open reading frame 172 | -4.04271 |
| LOC122455342 | testis-specific serine/proline-rich protein | -4.00954 |
| USP3 | ubiquitin specific peptidase 3 | -3.6971 |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 | -3.67537 |
| ADCY3 | adenylate cyclase 3 | -3.64396 |
| GOLM1 | golgi membrane protein 1 | -3.48702 |
| TSPAN31 | tetraspanin 31 | -3.41868 |
| EME1 | essential meiotic structure-specific endonuclease 1 | -3.25701 |
| PEX10 | peroxisomal biogenesis factor 10 | -3.224 |
| SGCE | sarcoglycan, epsilon | -3.18381 |
| TMEM263 | transmembrane protein 263 | -3.07831 |
| TOB1 | transducer of ERBB2, 1 | -3.03642 |
| MRPS34 | mitochondrial ribosomal protein S34 | -3.00755 |
| IL24 | interleukin 24 | -2.98441 |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase | -2.86898 |
| MAP3K15 | mitogen-activated protein kinase kinase kinase 15 | -2.82584 |
| TCP1 | t-complex 1 | -2.76968 |
| TNS2 | tensin 2 | -2.75527 |
| MLX | MLX, MAX dimerization protein | -2.71566 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | -2.68947 |
| FCMR | Fc fragment of IgM receptor | -2.68341 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -2.66258 |
| CCDC176 | coiled-coil domain containing 176 | -2.65407 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -2.64806 |
| LRRC24 | leucine rich repeat containing 24 | -2.64806 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -2.63221 |
| BCAS3 | breast carcinoma amplified sequence 3 | -2.63145 |
| POLG | polymerase (DNA directed), gamma | -2.62279 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -2.60062 |
| PROB1 | proline-rich basic protein 1 | -2.5547 |
| TRIM14 | tripartite motif containing 14 | -2.54561 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -2.51953 |
| AATK | apoptosis-associated tyrosine kinase | -2.51953 |
| C12ORF60 | chromosome 12 open reading frame 60 | -2.50244 |
| PRSS23 | protease, serine, 23 | -2.49966 |
| MED31 | mediator complex subunit 31 | -2.44634 |
| SAMD14 | sterile alpha motif domain containing 14 | -2.43833 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E | -2.42787 |
| BCL7A | B-cell CLL/lymphoma 7A | -2.41991 |
| VIM | vimentin | -2.40231 |
| SARNP | SAP domain containing ribonucleoprotein | -2.2572 |
| CD37 | CD37 molecule | -2.23967 |
| HBP1 | HMG-box transcription factor 1 | -2.23318 |
| TSEN54 | TSEN54 tRNA splicing endonuclease subunit | -2.18686 |
| TMEM140 | transmembrane protein 140 | -2.1705 |
| RAD9A | RAD9 homolog A (S. pombe) | -2.16954 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H | -2.10359 |
| SLC35F4 | solute carrier family 35, member F4 | -2.03874 |
| ZBTB46 | zinc finger and BTB domain containing 46 | -2.02174 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | -2.00038 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -1.97025 |
| RHOF | ras homolog family member F (in filopodia) | -1.96138 |
| WDR33 | WD repeat domain 33 | -1.92538 |
| FANCD2OS | FANCD2 opposite strand | -1.88998 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | -1.86262 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | -1.83101 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | -1.82544 |
| JTB | jumping translocation breakpoint | -1.8216 |
| KLLN | killin, p53-regulated DNA replication inhibitor | -1.81254 |
| PMCH | pro-melanin-concentrating hormone | -1.80863 |
| MPI | mannose phosphate isomerase | -1.8055 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -1.80158 |
| STAB1 | stabilin 1 | -1.78698 |
| CCNK | cyclin K | -1.72762 |
| RECQL4 | RecQ protein-like 4 | -1.72702 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta | -1.71754 |
| FAM184B | family with sequence similarity 184, member B | -1.70652 |
| PLLP | plasmolipin | -1.70143 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -1.68342 |
| RAB23 | RAB23, member RAS oncogene family | -1.66409 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -1.64664 |
| FAM92A1 | family with sequence similarity 92, member A1 | -1.64664 |