| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting MPI in TWNT-4 (human hepatic stellate cell) cell (Study accession: SRP355455) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_17595_KD_MPI_SRP355455 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBP4 | guanylate binding protein 4 | 20.0 |
| INHBA | inhibin, beta A | 20.0 |
| IFITM1 | interferon induced transmembrane protein 1 | 20.0 |
| BTC | betacellulin | 20.0 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 20.0 |
| NCF2 | neutrophil cytosolic factor 2 | 20.0 |
| DUSP10 | dual specificity phosphatase 10 | 20.0 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 20.0 |
| TNIP3 | TNFAIP3 interacting protein 3 | 20.0 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 20.0 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 20.0 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 20.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | 20.0 |
| MX1 | MX dynamin-like GTPase 1 | 20.0 |
| MX2 | MX dynamin-like GTPase 2 | 20.0 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 20.0 |
| IL4I1 | interleukin 4 induced 1 | 20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 20.0 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 20.0 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 20.0 |
| C3AR1 | complement component 3a receptor 1 | 20.0 |
| CLDN14 | claudin 14 | 20.0 |
| SMTNL1 | smoothelin-like 1 | 20.0 |
| CSF3 | colony stimulating factor 3 (granulocyte) | 20.0 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 20.0 |
| IL7R | interleukin 7 receptor | 20.0 |
| CREBRF | CREB3 regulatory factor | 20.0 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 20.0 |
| GMPR | guanosine monophosphate reductase | 20.0 |
| TLR3 | toll-like receptor 3 | 20.0 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 20.0 |
| IL6 | interleukin 6 | 20.0 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 20.0 |
| ESM1 | endothelial cell-specific molecule 1 | 20.0 |
| CLDN1 | claudin 1 | 20.0 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 20.0 |
| STC1 | stanniocalcin 1 | 20.0 |
| FNDC3A | fibronectin type III domain containing 3A | 20.0 |
| PITX3 | paired-like homeodomain 3 | 20.0 |
| IL1B | interleukin 1, beta | 20.0 |
| ANGPTL1 | angiopoietin-like 1 | 20.0 |
| GRIP2 | glutamate receptor interacting protein 2 | 20.0 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | 20.0 |
| MMP3 | matrix metallopeptidase 3 | 20.0 |
| GCH1 | GTP cyclohydrolase 1 | 20.0 |
| C11ORF96 | chromosome 11 open reading frame 96 | 20.0 |
| BATF2 | basic leucine zipper transcription factor, ATF-like 2 | 20.0 |
| EREG | epiregulin | 20.0 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 20.0 |
| IL18BP | interleukin 18 binding protein | 20.0 |
| IL1A | interleukin 1, alpha | 20.0 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 20.0 |
| HLA-F | major histocompatibility complex, class I, F | 20.0 |
| CTSS | cathepsin S | 20.0 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 20.0 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 20.0 |
| IFI27 | interferon, alpha-inducible protein 27 | 20.0 |
| CCL20 | chemokine (C-C motif) ligand 20 | 20.0 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 20.0 |
| MSR1 | macrophage scavenger receptor 1 | 20.0 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 20.0 |
| ICAM1 | intercellular adhesion molecule 1 | 20.0 |
| ISG15 | ISG15 ubiquitin-like modifier | 19.699 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 19.301 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 | 19.1549 |
| IFIH1 | interferon induced with helicase C domain 1 | 18.9208 |
| NEK7 | NIMA-related kinase 7 | 18.8539 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 18.6198 |
| FMNL2 | formin-like 2 | 18.5086 |
| LGMN | legumain | 18.3098 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 18.2147 |
| FST | follistatin | 18.2076 |
| USP18 | ubiquitin specific peptidase 18 | 17.9788 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 17.8665 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 17.7696 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 17.3372 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 16.9927 |
| C1S | complement component 1, s subcomponent | 16.9927 |
| KYNU | kynureninase | 16.9234 |
| BST2 | bone marrow stromal cell antigen 2 | 16.8567 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 16.6962 |
| GBP5 | guanylate binding protein 5 | 16.6891 |
| TBC1D7 | TBC1 domain family, member 7 | 16.6878 |
| CBX1 | chromobox homolog 1 | 16.6482 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 | 16.4116 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 16.3907 |
| BDKRB1 | bradykinin receptor B1 | 16.3691 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) | 16.2991 |
| RCSD1 | RCSD domain containing 1 | 16.2904 |
| TMEM140 | transmembrane protein 140 | 16.2507 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 16.1451 |
| EDNRB | endothelin receptor type B | 16.0877 |
| CD274 | CD274 molecule | 15.9725 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 15.8582 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 15.4302 |
| PAPL | iron/zinc purple acid phosphatase-like protein | 15.3896 |
| HSH2D | hematopoietic SH2 domain containing | 15.3727 |
| NINJ1 | ninjurin 1 | 15.3553 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL12A1 | collagen, type XII, alpha 1 | -20.0 |
| TMEM119 | transmembrane protein 119 | -20.0 |
| MCM6 | minichromosome maintenance complex component 6 | -20.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | -20.0 |
| THBS1 | thrombospondin 1 | -18.4949 |
| FAM101B | family with sequence similarity 101, member B | -18.1192 |
| PRKCA | protein kinase C, alpha | -18.0809 |
| MXD3 | MAX dimerization protein 3 | -17.7645 |
| SAPCD2 | suppressor APC domain containing 2 | -17.6162 |
| CPA4 | carboxypeptidase A4 | -17.5258 |
| RRM2 | ribonucleotide reductase M2 | -16.7716 |
| LIMK1 | LIM domain kinase 1 | -16.1503 |
| SDC1 | syndecan 1 | -14.982 |
| VCAN | versican | -14.9769 |
| MKI67 | marker of proliferation Ki-67 | -14.9423 |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 | -14.9238 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 | -14.8642 |
| LMNB1 | lamin B1 | -14.7578 |
| CLU | clusterin | -14.6285 |
| CCNF | cyclin F | -14.4042 |
| CLDN11 | claudin 11 | -14.1097 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -14.0366 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -13.9025 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -13.7651 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -13.7598 |
| FN1 | fibronectin 1 | -13.626 |
| KIF20A | kinesin family member 20A | -13.4964 |
| ADAMTS15 | ADAM metallopeptidase with thrombospondin type 1 motif, 15 | -13.3833 |
| COL14A1 | collagen, type XIV, alpha 1 | -13.2771 |
| TERT | telomerase reverse transcriptase | -13.2647 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -13.2253 |
| RPLP0 | ribosomal protein, large, P0 | -13.0182 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -12.8636 |
| OXTR | oxytocin receptor | -12.6927 |
| HMGB2 | high mobility group box 2 | -12.4976 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -12.4089 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -12.4089 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -12.2263 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -12.1743 |
| MCM4 | minichromosome maintenance complex component 4 | -12.1421 |
| RRM1 | ribonucleotide reductase M1 | -12.1281 |
| MXRA7 | matrix-remodelling associated 7 | -12.0603 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -11.9752 |
| TFRC | transferrin receptor | -11.9659 |
| RPL3 | ribosomal protein L3 | -11.8981 |
| COL1A2 | collagen, type I, alpha 2 | -11.7936 |
| NEGR1 | neuronal growth regulator 1 | -11.7389 |
| WDR34 | WD repeat domain 34 | -11.5459 |
| SLC25A39 | solute carrier family 25, member 39 | -11.4239 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -11.3583 |
| STMN1 | stathmin 1 | -11.3552 |
| CENPM | centromere protein M | -11.2941 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -11.2517 |
| CYBRD1 | cytochrome b reductase 1 | -11.2476 |
| PTGFRN | prostaglandin F2 receptor inhibitor | -11.1441 |
| FLNA | filamin A, alpha | -11.0476 |
| PRR11 | proline rich 11 | -10.6609 |
| RIN1 | Ras and Rab interactor 1 | -10.6587 |
| LMNB2 | lamin B2 | -10.6327 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -10.6059 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -10.5906 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -10.5814 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -10.5321 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -10.5038 |
| ANLN | anillin, actin binding protein | -10.4636 |
| ASF1B | anti-silencing function 1B histone chaperone | -10.4368 |
| ESCO2 | establishment of sister chromatid cohesion N-acetyltransferase 2 | -10.4204 |
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | -10.381 |
| TCF19 | transcription factor 19 | -10.2606 |
| RAB3B | RAB3B, member RAS oncogene family | -10.2594 |
| FEN1 | flap structure-specific endonuclease 1 | -10.201 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -10.1635 |
| TK1 | thymidine kinase 1, soluble | -10.1458 |
| H2AFV | H2A histone family, member V | -10.1105 |
| CDCA3 | cell division cycle associated 3 | -10.0766 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -10.0014 |
| LRRC2 | leucine rich repeat containing 2 | -9.95496 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | -9.92153 |
| HN1L | hematological and neurological expressed 1-like | -9.79896 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -9.73158 |
| FSCN1 | fascin actin-bundling protein 1 | -9.72745 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -9.67715 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -9.54552 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -9.30891 |
| RPL21 | ribosomal protein L21 | -9.28046 |
| TTPAL | tocopherol (alpha) transfer protein-like | -9.26257 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -9.26132 |
| CCNG1 | cyclin G1 | -9.22291 |
| TYMS | thymidylate synthetase | -9.21035 |
| HIC1 | hypermethylated in cancer 1 | -9.18226 |
| H2AFX | H2A histone family, member X | -9.07389 |
| KIF4A | kinesin family member 4A | -9.07037 |
| CMBL | carboxymethylenebutenolidase homolog (Pseudomonas) | -9.05156 |
| SETD7 | SET domain containing (lysine methyltransferase) 7 | -8.98283 |
| LOXL1 | lysyl oxidase-like 1 | -8.87486 |
| FHL2 | four and a half LIM domains 2 | -8.86639 |
| CDC6 | cell division cycle 6 | -8.801 |
| DHCR24 | 24-dehydrocholesterol reductase | -8.79236 |
| TMEM97 | transmembrane protein 97 | -8.78224 |
| MCM7 | minichromosome maintenance complex component 7 | -8.72094 |
