| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting USP18 in 7304.1 Skeletal muscle cell line cell line (Study accession: SRP364866) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_253_KD_USP18_SRP364866 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 20.0 |
| CNN3 | calponin 3, acidic | 20.0 |
| ZNF106 | zinc finger protein 106 | 20.0 |
| CTGF | connective tissue growth factor | 20.0 |
| C1ORF198 | chromosome 1 open reading frame 198 | 20.0 |
| PACS2 | phosphofurin acidic cluster sorting protein 2 | 20.0 |
| PDLIM3 | PDZ and LIM domain 3 | 20.0 |
| TNK2 | tyrosine kinase, non-receptor, 2 | 20.0 |
| HES6 | hes family bHLH transcription factor 6 | 20.0 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 20.0 |
| EHD1 | EH-domain containing 1 | 20.0 |
| SIRT2 | sirtuin 2 | 20.0 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 20.0 |
| TRIM72 | tripartite motif containing 72, E3 ubiquitin protein ligase | 20.0 |
| SSH1 | slingshot protein phosphatase 1 | 20.0 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | 20.0 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) | 20.0 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| CRIP2 | cysteine-rich protein 2 | 20.0 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 20.0 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 20.0 |
| TNS1 | tensin 1 | 20.0 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 20.0 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 20.0 |
| METRNL | meteorin, glial cell differentiation regulator-like | 20.0 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 20.0 |
| MYOG | myogenin (myogenic factor 4) | 20.0 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 20.0 |
| GSN | gelsolin | 20.0 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 | 20.0 |
| MYO18B | myosin XVIIIB | 20.0 |
| CCND1 | cyclin D1 | 20.0 |
| CCND2 | cyclin D2 | 20.0 |
| TSPAN9 | tetraspanin 9 | 20.0 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 20.0 |
| ARF4 | ADP-ribosylation factor 4 | 20.0 |
| DMPK | dystrophia myotonica-protein kinase | 20.0 |
| CLTB | clathrin, light chain B | 20.0 |
| CLU | clusterin | 20.0 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 20.0 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 20.0 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 20.0 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 20.0 |
| MVP | major vault protein | 20.0 |
| CYB5R1 | cytochrome b5 reductase 1 | 20.0 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 20.0 |
| GOLGA2 | golgin A2 | 20.0 |
| BAX | BCL2-associated X protein | 20.0 |
| CDV3 | CDV3 homolog (mouse) | 20.0 |
| ITGA6 | integrin, alpha 6 | 20.0 |
| EFHD2 | EF-hand domain family, member D2 | 20.0 |
| MRAS | muscle RAS oncogene homolog | 20.0 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 20.0 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 | 20.0 |
| SERINC2 | serine incorporator 2 | 20.0 |
| DVL3 | dishevelled segment polarity protein 3 | 20.0 |
| KLF2 | Kruppel-like factor 2 | 20.0 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 20.0 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 20.0 |
| COL18A1 | collagen, type XVIII, alpha 1 | 20.0 |
| DSP | desmoplakin | 20.0 |
| CHKB | choline kinase beta | 20.0 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 20.0 |
| HN1 | hematological and neurological expressed 1 | 20.0 |
| ADAM19 | ADAM metallopeptidase domain 19 | 20.0 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 20.0 |
| RIN2 | Ras and Rab interactor 2 | 20.0 |
| ABLIM3 | actin binding LIM protein family, member 3 | 20.0 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 20.0 |
| ATP10A | ATPase, class V, type 10A | 20.0 |
| NCKAP5L | NCK-associated protein 5-like | 20.0 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 20.0 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 20.0 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | 20.0 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 20.0 |
| LOC102724428 | serine/threonine-protein kinase SIK1 | 20.0 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 20.0 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 20.0 |
| LIMK1 | LIM domain kinase 1 | 20.0 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 20.0 |
| CCNY | cyclin Y | 20.0 |
| IL32 | interleukin 32 | 20.0 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 20.0 |
| LMCD1 | LIM and cysteine-rich domains 1 | 20.0 |
| PRDX6 | peroxiredoxin 6 | 20.0 |
| WARS | tryptophanyl-tRNA synthetase | 20.0 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 20.0 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 20.0 |
| H3F3A | H3 histone, family 3A | 20.0 |
| ALPK3 | alpha-kinase 3 | 20.0 |
| BIN1 | bridging integrator 1 | 20.0 |
| FNDC5 | fibronectin type III domain containing 5 | 20.0 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 20.0 |
| CHN1 | chimerin 1 | 20.0 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | 20.0 |
| HMOX1 | heme oxygenase 1 | 20.0 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 20.0 |
| USO1 | USO1 vesicle transport factor | 20.0 |
| RHOB | ras homolog family member B | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CENPI | centromere protein I | -20.0 |
| KIAA1211L | KIAA1211-like | -20.0 |
| METTL7A | methyltransferase like 7A | -20.0 |
| KIAA0101 | KIAA0101 | -20.0 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -20.0 |
| C1ORF112 | chromosome 1 open reading frame 112 | -20.0 |
| MUC1 | mucin 1, cell surface associated | -20.0 |
| LOC81691 | exonuclease NEF-sp | -20.0 |
| PASK | PAS domain containing serine/threonine kinase | -20.0 |
| HPCAL4 | hippocalcin like 4 | -20.0 |
| DEPDC1B | DEP domain containing 1B | -20.0 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -20.0 |
| SH2D6 | SH2 domain containing 6 | -20.0 |
| CEP152 | centrosomal protein 152kDa | -20.0 |
| CENPH | centromere protein H | -20.0 |
| RMI1 | RecQ mediated genome instability 1 | -20.0 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -20.0 |
| BRCA2 | breast cancer 2, early onset | -20.0 |
| SGOL1 | shugoshin-like 1 (S. pombe) | -20.0 |
| C1ORF21 | chromosome 1 open reading frame 21 | -20.0 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | -20.0 |
| GSG2 | germ cell associated 2 (haspin) | -20.0 |
| PTGFR | prostaglandin F receptor (FP) | -20.0 |
| VRK1 | vaccinia related kinase 1 | -20.0 |
| MMS22L | MMS22-like, DNA repair protein | -20.0 |
| AGTR1 | angiotensin II receptor, type 1 | -20.0 |
| MRPL36 | mitochondrial ribosomal protein L36 | -20.0 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | -20.0 |
| SOCS2 | suppressor of cytokine signaling 2 | -20.0 |
| CNTRL | centriolin | -20.0 |
| PTK2B | protein tyrosine kinase 2 beta | -20.0 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -20.0 |
| DDIAS | DNA damage-induced apoptosis suppressor | -20.0 |
| BLM | Bloom syndrome, RecQ helicase-like | -20.0 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -20.0 |
| ESCO2 | establishment of sister chromatid cohesion N-acetyltransferase 2 | -20.0 |
| ORC1 | origin recognition complex, subunit 1 | -20.0 |
| PSMC3IP | PSMC3 interacting protein | -20.0 |
| APOLD1 | apolipoprotein L domain containing 1 | -20.0 |
| TPRKB | TP53RK binding protein | -20.0 |
| HELLS | helicase, lymphoid-specific | -20.0 |
| ANGPT1 | angiopoietin 1 | -20.0 |
| E2F2 | E2F transcription factor 2 | -20.0 |
| E2F8 | E2F transcription factor 8 | -20.0 |
| CDC7 | cell division cycle 7 | -20.0 |
| TMEM97 | transmembrane protein 97 | -20.0 |
| CCDC15 | coiled-coil domain containing 15 | -20.0 |
| CCDC18 | coiled-coil domain containing 18 | -20.0 |
| ARHGEF39 | Rho guanine nucleotide exchange factor (GEF) 39 | -20.0 |
| NFIB | nuclear factor I/B | -20.0 |
| LRRC20 | leucine rich repeat containing 20 | -20.0 |
| CCDC77 | coiled-coil domain containing 77 | -20.0 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -20.0 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -20.0 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -20.0 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -20.0 |
| GARS | glycyl-tRNA synthetase | -20.0 |
| MCM8 | minichromosome maintenance complex component 8 | -20.0 |
| IER3IP1 | immediate early response 3 interacting protein 1 | -20.0 |
| EME1 | essential meiotic structure-specific endonuclease 1 | -20.0 |
| MTFR2 | mitochondrial fission regulator 2 | -20.0 |
| SFRP5 | secreted frizzled-related protein 5 | -20.0 |
| CDCA7 | cell division cycle associated 7 | -20.0 |
| FAM111B | family with sequence similarity 111, member B | -20.0 |
| RMI2 | RecQ mediated genome instability 2 | -20.0 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -20.0 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -20.0 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -20.0 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -20.0 |
| CEP128 | centrosomal protein 128kDa | -20.0 |
| TRAIP | TRAF interacting protein | -20.0 |
| CTSV | cathepsin V | -20.0 |
| TICRR | TOPBP1-interacting checkpoint and replication regulator | -20.0 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -20.0 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -20.0 |
| DNA2 | DNA replication helicase/nuclease 2 | -20.0 |
| CDC25C | cell division cycle 25C | -20.0 |
| KIF18A | kinesin family member 18A | -20.0 |
| ERCC6L | excision repair cross-complementation group 6-like | -20.0 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -20.0 |
| KLHL23 | kelch-like family member 23 | -20.0 |
| SPIN4 | spindlin family, member 4 | -20.0 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -20.0 |
| C16ORF59 | chromosome 16 open reading frame 59 | -20.0 |
| CEP44 | centrosomal protein 44kDa | -20.0 |
| FAM72B | family with sequence similarity 72, member B | -20.0 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 | -20.0 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -20.0 |
| C18ORF54 | chromosome 18 open reading frame 54 | -20.0 |
| RAD51AP1 | RAD51 associated protein 1 | -20.0 |
| LCNL1 | lipocalin-like 1 | -20.0 |
| ARHGAP28 | Rho GTPase activating protein 28 | -20.0 |
| FAM132B | family with sequence similarity 132, member B | -20.0 |
| CDCA7L | cell division cycle associated 7-like | -20.0 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -20.0 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -20.0 |
| PNMT | phenylethanolamine N-methyltransferase | -20.0 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | -20.0 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -20.0 |
| CENPL | centromere protein L | -20.0 |
