| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SNHG7 in breast cancer cell MCF7 cell line (Study accession: SRP179498) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_2543_KD_SNHG7_SRP179498 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 20.0 |
| CCDC170 | coiled-coil domain containing 170 | 20.0 |
| BBIP1 | BBSome interacting protein 1 | 20.0 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 20.0 |
| C8ORF88 | chromosome 8 open reading frame 88 | 20.0 |
| NUP88 | nucleoporin 88kDa | 20.0 |
| GANC | glucosidase, alpha; neutral C | 16.1681 |
| ZNF711 | zinc finger protein 711 | 14.3272 |
| CDH13 | cadherin 13 | 13.6333 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 12.3479 |
| KHNYN | KH and NYN domain containing | 11.411 |
| JTB | jumping translocation breakpoint | 10.9449 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 10.6243 |
| LRRC14 | leucine rich repeat containing 14 | 10.3251 |
| CSNK1D | casein kinase 1, delta | 9.49165 |
| ANKRD6 | ankyrin repeat domain 6 | 9.12074 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 8.37353 |
| PTPMT1 | protein tyrosine phosphatase, mitochondrial 1 | 8.16477 |
| WDR6 | WD repeat domain 6 | 8.08749 |
| FAM71E1 | family with sequence similarity 71, member E1 | 7.83944 |
| CCDC176 | coiled-coil domain containing 176 | 7.62262 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 7.54846 |
| ZNF263 | zinc finger protein 263 | 7.54011 |
| FN1 | fibronectin 1 | 7.39393 |
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 7.26789 |
| TRIM14 | tripartite motif containing 14 | 7.00741 |
| RECQL4 | RecQ protein-like 4 | 6.99197 |
| RNF32 | ring finger protein 32 | 6.67377 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 6.38684 |
| C2ORF16 | chromosome 2 open reading frame 16 | 6.37816 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 6.23925 |
| C11ORF57 | chromosome 11 open reading frame 57 | 6.1563 |
| RNASEH2C | ribonuclease H2, subunit C | 6.04844 |
| SOX3 | SRY (sex determining region Y)-box 3 | 6.04769 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 6.04391 |
| TREH | trehalase (brush-border membrane glycoprotein) | 5.58436 |
| PROB1 | proline-rich basic protein 1 | 5.32243 |
| DENND1C | DENN/MADD domain containing 1C | 5.32243 |
| C1ORF56 | chromosome 1 open reading frame 56 | 5.17041 |
| SH3D21 | SH3 domain containing 21 | 5.02034 |
| ABI2 | abl-interactor 2 | 4.92852 |
| SZT2 | seizure threshold 2 homolog (mouse) | 4.92774 |
| DNM2 | dynamin 2 | 4.7802 |
| PAQR3 | progestin and adipoQ receptor family member III | 4.75118 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 4.61159 |
| SDR39U1 | short chain dehydrogenase/reductase family 39U, member 1 | 4.6002 |
| CCDC78 | coiled-coil domain containing 78 | 4.59854 |
| PSD | pleckstrin and Sec7 domain containing | 4.54495 |
| TMED8 | transmembrane emp24 protein transport domain containing 8 | 4.43165 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 4.41012 |
| MED31 | mediator complex subunit 31 | 4.37788 |
| MARS | methionyl-tRNA synthetase | 4.37037 |
| CACNA2D4 | calcium channel, voltage-dependent, alpha 2/delta subunit 4 | 4.33194 |
| SYCP3 | synaptonemal complex protein 3 | 4.29732 |
| GAB2 | GRB2-associated binding protein 2 | 4.24238 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 4.23227 |
| GTPBP1 | GTP binding protein 1 | 4.23227 |
| TVP23A | trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) | 4.15756 |
| ARSG | arylsulfatase G | 4.14158 |
| SLC46A1 | solute carrier family 46 (folate transporter), member 1 | 4.07096 |
| SRRM2 | serine/arginine repetitive matrix 2 | 4.07096 |
| NCBP2L | nuclear cap binding protein subunit 2-like | 4.06634 |
| ERI2 | ERI1 exoribonuclease family member 2 | 3.90493 |
| ACBD6 | acyl-CoA binding domain containing 6 | 3.86797 |
| NOP16 | NOP16 nucleolar protein | 3.72765 |
| MAX | MYC associated factor X | 3.71046 |
| PIAS3 | protein inhibitor of activated STAT, 3 | 3.71046 |
| INO80E | INO80 complex subunit E | 3.70554 |
| NAA20 | N(alpha)-acetyltransferase 20, NatB catalytic subunit | 3.66403 |
| SERINC4 | serine incorporator 4 | 3.59021 |
| COG5 | component of oligomeric golgi complex 5 | 3.54574 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) | 3.53877 |
| SIAE | sialic acid acetylesterase | 3.52491 |
| CERS2 | ceramide synthase 2 | 3.46377 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 3.42812 |
| TMEM115 | transmembrane protein 115 | 3.38762 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 3.37514 |
| FAM228B | family with sequence similarity 228, member B | 3.27837 |
| LOC101927685 | heat shock transcription factor, X-linked-like | 3.20661 |
| ZNF337 | zinc finger protein 337 | 3.20661 |
| YPEL3 | yippee-like 3 (Drosophila) | 3.09192 |
| BDNF | brain-derived neurotrophic factor | 3.07585 |
| PQBP1 | polyglutamine binding protein 1 | 3.06295 |
| ERVH48-1 | endogenous retrovirus group 48, member 1 | 3.05338 |
| USP37 | ubiquitin specific peptidase 37 | 3.04228 |
| PEX10 | peroxisomal biogenesis factor 10 | 2.94167 |
| EMC9 | ER membrane protein complex subunit 9 | 2.91712 |
| CCDC152 | coiled-coil domain containing 152 | 2.88981 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 2.86015 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 2.8598 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 2.82399 |
| RMDN1 | regulator of microtubule dynamics 1 | 2.73672 |
| TOB1 | transducer of ERBB2, 1 | 2.73357 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | 2.71776 |
| WDR24 | WD repeat domain 24 | 2.71776 |
| NKAIN4 | Na+/K+ transporting ATPase interacting 4 | 2.70958 |
| SHARPIN | SHANK-associated RH domain interactor | 2.66787 |
| GRK6 | G protein-coupled receptor kinase 6 | 2.66659 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | 2.65317 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 | 2.65189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POLR3H | polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) | -20.0 |
| C12ORF60 | chromosome 12 open reading frame 60 | -20.0 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -20.0 |
| FSIP1 | fibrous sheath interacting protein 1 | -20.0 |
| SNX22 | sorting nexin 22 | -20.0 |
| CTNS | cystinosin, lysosomal cystine transporter | -20.0 |
| ATG7 | autophagy related 7 | -20.0 |
| MXD3 | MAX dimerization protein 3 | -20.0 |
| TMEM186 | transmembrane protein 186 | -20.0 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | -18.6383 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | -18.041 |
| FAM69B | family with sequence similarity 69, member B | -16.2995 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -15.756 |
| RELL1 | RELT-like 1 | -14.39 |
| PCED1B | PC-esterase domain containing 1B | -14.1463 |
| KRT17 | keratin 17, type I | -13.5361 |
| RHOF | ras homolog family member F (in filopodia) | -13.4806 |
| BMP6 | bone morphogenetic protein 6 | -12.9569 |
| DEK | DEK proto-oncogene | -12.873 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | -12.4128 |
| TMEM120B | transmembrane protein 120B | -11.7662 |
| TP53I13 | tumor protein p53 inducible protein 13 | -11.7662 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | -11.7631 |
| FAM166A | family with sequence similarity 166, member A | -10.5263 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | -10.4628 |
| OTUD4 | OTU deubiquitinase 4 | -10.3373 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -10.1956 |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | -9.40114 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 | -9.1188 |
| IRS1 | insulin receptor substrate 1 | -9.10589 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -8.77401 |
| PKN3 | protein kinase N3 | -8.3295 |
| ADGRF3 | adhesion G protein-coupled receptor F3 | -8.14821 |
| PFDN6 | prefoldin subunit 6 | -7.54471 |
| KRT8 | keratin 8, type II | -7.25757 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -7.23521 |
| MAP3K15 | mitogen-activated protein kinase kinase kinase 15 | -7.15306 |
| TUBA1C | tubulin, alpha 1c | -7.10231 |
| CCDC42B | coiled-coil domain containing 42B | -7.07981 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | -6.93872 |
| B9D1 | B9 protein domain 1 | -6.82543 |
| ORAOV1 | oral cancer overexpressed 1 | -6.50196 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -6.36023 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | -5.8709 |
| ENO1 | enolase 1, (alpha) | -5.8042 |
| SAMD11 | sterile alpha motif domain containing 11 | -5.63732 |
| BMP7 | bone morphogenetic protein 7 | -5.55965 |
| TSPAN31 | tetraspanin 31 | -5.47005 |
| KRT23 | keratin 23, type I | -5.37479 |
| BCCIP | BRCA2 and CDKN1A interacting protein | -5.32243 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -5.11526 |
| C21ORF2 | chromosome 21 open reading frame 2 | -4.95186 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -4.88836 |
| IGF1R | insulin-like growth factor 1 receptor | -4.84676 |
| TRABD2A | TraB domain containing 2A | -4.84676 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | -4.65325 |
| PLK2 | polo-like kinase 2 | -4.57771 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -4.48597 |
| PMEL | premelanosome protein | -4.46801 |
| GPR39 | G protein-coupled receptor 39 | -4.45177 |
| KRT40 | keratin 40, type I | -4.44324 |
| RBM4B | RNA binding motif protein 4B | -4.41993 |
| GLIPR1 | GLI pathogenesis-related 1 | -4.37463 |
| C14ORF79 | chromosome 14 open reading frame 79 | -4.35021 |
| SYNC | syncoilin, intermediate filament protein | -4.32973 |
| PLLP | plasmolipin | -4.25564 |
| COL9A3 | collagen, type IX, alpha 3 | -4.24238 |
| ANAPC10 | anaphase promoting complex subunit 10 | -4.23528 |
| KIF5A | kinesin family member 5A | -4.23056 |
| DALRD3 | DALR anticodon binding domain containing 3 | -4.1255 |
| C12ORF65 | chromosome 12 open reading frame 65 | -4.11733 |
| TPM3 | tropomyosin 3 | -4.06634 |
| KRI1 | KRI1 homolog (S. cerevisiae) | -4.01299 |
| RPL10A | ribosomal protein L10a | -4.01208 |
| RPL14 | ribosomal protein L14 | -3.98071 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -3.89379 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | -3.85699 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -3.8282 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -3.82023 |
| CLVS1 | clavesin 1 | -3.78966 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -3.75973 |
| AREG | amphiregulin | -3.75924 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | -3.69727 |
| SULF2 | sulfatase 2 | -3.68579 |
| S100A10 | S100 calcium binding protein A10 | -3.68579 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -3.64083 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | -3.63742 |
| PKM | pyruvate kinase, muscle | -3.61797 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -3.60557 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | -3.5744 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -3.5707 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -3.56381 |
| MED12L | mediator complex subunit 12-like | -3.49363 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -3.48295 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -3.42812 |
| BRI3 | brain protein I3 | -3.42033 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -3.37142 |
| STAB1 | stabilin 1 | -3.3552 |
| RPL30 | ribosomal protein L30 | -3.32579 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -3.20722 |
