Perturb_2745_KD_EMP2_SRP215373 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting EMP2 in breast cancer cell SUM149PT cell (Study accession: SRP215373) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

42 genes differentially expressed following the Perturb_2745_KD_EMP2_SRP215373 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
FLNA filamin A, alpha 13.5213
PCSK7 proprotein convertase subtilisin/kexin type 7 6.01279
FN1 fibronectin 1 5.35193
C12ORF73 chromosome 12 open reading frame 73 4.75705
CALR calreticulin 4.52715
IFNLR1 interferon, lambda receptor 1 3.9106
ITGB1BP1 integrin beta 1 binding protein 1 3.08992
CBR4 carbonyl reductase 4 2.85524
PMEPA1 prostate transmembrane protein, androgen induced 1 2.53817
LDLRAD2 low density lipoprotein receptor class A domain containing 2 2.47711
COL4A2 collagen, type IV, alpha 2 2.19757
C5ORF45 chromosome 5 open reading frame 45 1.98106
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 1.89415
TCP1 t-complex 1 1.59916
PLEC plectin 1.57345
MYH9 myosin, heavy chain 9, non-muscle 1.57155
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.57155
INTS8 integrator complex subunit 8 1.48377

decreased expression

Symbol Name Standardized Value
PHKG1 phosphorylase kinase, gamma 1 (muscle) -20.0
NDRG1 N-myc downstream regulated 1 -9.79451
LRRC75A leucine rich repeat containing 75A -5.87619
CASP14 caspase 14, apoptosis-related cysteine peptidase -5.36647
ELP2 elongator acetyltransferase complex subunit 2 -5.2476
C12ORF60 chromosome 12 open reading frame 60 -3.9295
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) -3.9106
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -3.81219
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -3.69272
ERAP1 endoplasmic reticulum aminopeptidase 1 -3.64812
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -2.92087
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39 -2.77776
DSE dermatan sulfate epimerase -2.77776
PROB1 proline-rich basic protein 1 -2.53817
SZT2 seizure threshold 2 homolog (mouse) -2.47711
CTSD cathepsin D -2.47711
ABI2 abl-interactor 2 -2.38254
NME7 NME/NM23 family member 7 -2.37867
SYT11 synaptotagmin XI -2.28881
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) -2.0457
MSLN mesothelin -1.68635
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.68635
TUBB6 tubulin, beta 6 class V -1.63759
MFSD11 major facilitator superfamily domain containing 11 -1.55784