| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting STING1 in breast cancer cell SUM159PT cell line (Study accession: SRP358852) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_2748_KO_STING1_SRP358852 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPNMB | glycoprotein (transmembrane) nmb | 20.0 |
| SLC44A2 | solute carrier family 44 (choline transporter), member 2 | 20.0 |
| S100A4 | S100 calcium binding protein A4 | 20.0 |
| TSC22D1 | TSC22 domain family, member 1 | 20.0 |
| FBLN1 | fibulin 1 | 20.0 |
| FBLN5 | fibulin 5 | 20.0 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 20.0 |
| VSTM2L | V-set and transmembrane domain containing 2 like | 20.0 |
| PDZD2 | PDZ domain containing 2 | 20.0 |
| CNTNAP2 | contactin associated protein-like 2 | 20.0 |
| KRT75 | keratin 75, type II | 20.0 |
| FN1 | fibronectin 1 | 20.0 |
| HMGB1 | high mobility group box 1 | 20.0 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 20.0 |
| NPR3 | natriuretic peptide receptor 3 | 20.0 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 20.0 |
| CCDC80 | coiled-coil domain containing 80 | 20.0 |
| OLFML2A | olfactomedin-like 2A | 20.0 |
| SDC2 | syndecan 2 | 20.0 |
| DGKH | diacylglycerol kinase, eta | 20.0 |
| MID1IP1 | MID1 interacting protein 1 | 20.0 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 20.0 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 20.0 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 20.0 |
| C3 | complement component 3 | 20.0 |
| KDR | kinase insert domain receptor | 20.0 |
| STAC2 | SH3 and cysteine rich domain 2 | 20.0 |
| MRC2 | mannose receptor, C type 2 | 20.0 |
| RPL21 | ribosomal protein L21 | 20.0 |
| COL3A1 | collagen, type III, alpha 1 | 20.0 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 20.0 |
| PDS5B | PDS5 cohesin associated factor B | 20.0 |
| GAS6 | growth arrest-specific 6 | 20.0 |
| CDC16 | cell division cycle 16 | 20.0 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 20.0 |
| CHAMP1 | chromosome alignment maintaining phosphoprotein 1 | 20.0 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 | 20.0 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 20.0 |
| MEGF6 | multiple EGF-like-domains 6 | 20.0 |
| CUL4A | cullin 4A | 20.0 |
| CRYAB | crystallin, alpha B | 20.0 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 20.0 |
| COL4A4 | collagen, type IV, alpha 4 | 20.0 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 20.0 |
| CADPS2 | Ca++-dependent secretion activator 2 | 20.0 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 20.0 |
| TMSB4X | thymosin beta 4, X-linked | 20.0 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 20.0 |
| FAM20C | family with sequence similarity 20, member C | 20.0 |
| MCAM | melanoma cell adhesion molecule | 20.0 |
| BTNL9 | butyrophilin-like 9 | 20.0 |
| S100A10 | S100 calcium binding protein A10 | 20.0 |
| ZNF704 | zinc finger protein 704 | 20.0 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 20.0 |
| MLIP | muscular LMNA-interacting protein | 20.0 |
| MAOA | monoamine oxidase A | 20.0 |
| LAMB2 | laminin, beta 2 (laminin S) | 20.0 |
| RASA3 | RAS p21 protein activator 3 | 20.0 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 20.0 |
| RTN1 | reticulon 1 | 20.0 |
| SLC25A30 | solute carrier family 25, member 30 | 20.0 |
| TUBA1A | tubulin, alpha 1a | 20.0 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 20.0 |
| TP63 | tumor protein p63 | 20.0 |
| PROS1 | protein S (alpha) | 20.0 |
| F10 | coagulation factor X | 20.0 |
| NEURL1B | neuralized E3 ubiquitin protein ligase 1B | 20.0 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 20.0 |
| MXD4 | MAX dimerization protein 4 | 20.0 |
| GTF3A | general transcription factor IIIA | 20.0 |
| COL5A3 | collagen, type V, alpha 3 | 20.0 |
| LAMP1 | lysosomal-associated membrane protein 1 | 20.0 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 20.0 |
| TFDP1 | transcription factor Dp-1 | 20.0 |
| FAM213A | family with sequence similarity 213, member A | 20.0 |
| CDON | cell adhesion associated, oncogene regulated | 20.0 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 20.0 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 20.0 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 20.0 |
| FOXO1 | forkhead box O1 | 20.0 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 19.5229 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 19.5229 |
| COL6A1 | collagen, type VI, alpha 1 | 19.301 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | 19.0458 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 18.8239 |
| APOE | apolipoprotein E | 18.7447 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | 18.4949 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 18.4559 |
| CADM3 | cell adhesion molecule 3 | 18.301 |
| FOXN3 | forkhead box N3 | 17.9508 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 17.6968 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 17.6478 |
| COL12A1 | collagen, type XII, alpha 1 | 17.5986 |
| SERINC2 | serine incorporator 2 | 17.5986 |
| KIF20A | kinesin family member 20A | 17.466 |
| CRISP3 | cysteine-rich secretory protein 3 | 17.1746 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 16.8804 |
| SLC46A3 | solute carrier family 46, member 3 | 16.7951 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 16.7542 |
| ARHGAP29 | Rho GTPase activating protein 29 | 16.6289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | -20.0 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -20.0 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -20.0 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -20.0 |
| FOXA2 | forkhead box A2 | -20.0 |
| TNC | tenascin C | -20.0 |
| CA9 | carbonic anhydrase IX | -20.0 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -20.0 |
| CA12 | carbonic anhydrase XII | -20.0 |
| DIO2 | deiodinase, iodothyronine, type II | -20.0 |
| DBN1 | drebrin 1 | -20.0 |
| VCL | vinculin | -20.0 |
| EFNB2 | ephrin-B2 | -20.0 |
| TENM3 | teneurin transmembrane protein 3 | -20.0 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -20.0 |
| MAGEC2 | melanoma antigen family C2 | -20.0 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -20.0 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | -20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -20.0 |
| KRT81 | keratin 81, type II | -20.0 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -20.0 |
| IL7R | interleukin 7 receptor | -20.0 |
| CP | ceruloplasmin (ferroxidase) | -20.0 |
| SAA1 | serum amyloid A1 | -20.0 |
| SLC12A8 | solute carrier family 12, member 8 | -20.0 |
| RUNX2 | runt-related transcription factor 2 | -20.0 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -20.0 |
| TLR4 | toll-like receptor 4 | -20.0 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | -20.0 |
| COL6A3 | collagen, type VI, alpha 3 | -20.0 |
| VCAN | versican | -20.0 |
| COL1A1 | collagen, type I, alpha 1 | -20.0 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | -20.0 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -20.0 |
| LOXL2 | lysyl oxidase-like 2 | -20.0 |
| CDCP1 | CUB domain containing protein 1 | -20.0 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -20.0 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -20.0 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -20.0 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -20.0 |
| F2R | coagulation factor II (thrombin) receptor | -20.0 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -20.0 |
| IL1RL1 | interleukin 1 receptor-like 1 | -20.0 |
| CPA4 | carboxypeptidase A4 | -20.0 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -20.0 |
| CCNA2 | cyclin A2 | -20.0 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -20.0 |
| TAGLN | transgelin | -20.0 |
| TGM2 | transglutaminase 2 | -20.0 |
| ADRA1D | adrenoceptor alpha 1D | -20.0 |
| BEX1 | brain expressed, X-linked 1 | -20.0 |
| DMKN | dermokine | -19.699 |
| CNTN1 | contactin 1 | -19.699 |
| PCDH7 | protocadherin 7 | -19.0969 |
| HMGA1 | high mobility group AT-hook 1 | -18.2366 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 | -18.1308 |
| KIFC3 | kinesin family member C3 | -18.0757 |
| CADM1 | cell adhesion molecule 1 | -17.6696 |
| KRT80 | keratin 80, type II | -17.3605 |
| SLIT2 | slit homolog 2 (Drosophila) | -17.2668 |
| EGR1 | early growth response 1 | -17.1675 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -16.8557 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -16.7778 |
| ISG15 | ISG15 ubiquitin-like modifier | -16.7258 |
| TENM2 | teneurin transmembrane protein 2 | -16.6334 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -16.5962 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -16.388 |
| ARHGAP23 | Rho GTPase activating protein 23 | -16.2464 |
| MYO1B | myosin IB | -16.1753 |
| TGFB1 | transforming growth factor, beta 1 | -15.847 |
| ERCC6 | excision repair cross-complementation group 6 | -15.7307 |
| DNER | delta/notch-like EGF repeat containing | -15.6008 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -15.3704 |
| FHL2 | four and a half LIM domains 2 | -15.2133 |
| NEBL | nebulette | -15.1524 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -15.0309 |
| KLK2 | kallikrein-related peptidase 2 | -14.812 |
| IGF1R | insulin-like growth factor 1 receptor | -14.6886 |
| DNM1 | dynamin 1 | -14.2504 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -14.1711 |
| TMEM156 | transmembrane protein 156 | -14.1459 |
| ELFN2 | extracellular leucine-rich repeat and fibronectin type III domain containing 2 | -14.0915 |
| FGFR1 | fibroblast growth factor receptor 1 | -13.8866 |
| TMEM173 | transmembrane protein 173 | -13.6536 |
| TP53I11 | tumor protein p53 inducible protein 11 | -13.5744 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -13.536 |
| MTUS1 | microtubule associated tumor suppressor 1 | -13.467 |
| DUSP5 | dual specificity phosphatase 5 | -13.3291 |
| C12ORF75 | chromosome 12 open reading frame 75 | -13.0277 |
| TXNRD2 | thioredoxin reductase 2 | -12.79 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -12.7591 |
| CPE | carboxypeptidase E | -12.3576 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -12.2164 |
| SYT11 | synaptotagmin XI | -12.2156 |
| NNMT | nicotinamide N-methyltransferase | -12.0371 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -12.0371 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -11.98 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -11.766 |
| TNS4 | tensin 4 | -11.6366 |
