| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SNHG1 in carboplatin resistance retinoblastoma cell line Weri-RB1/CRP cell line (Study accession: SRP313438) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_3016_KD_SNHG1_SRP313438 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGF2 | fibroblast growth factor 2 (basic) | 20.0 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 20.0 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 20.0 |
| TOB1 | transducer of ERBB2, 1 | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 20.0 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 20.0 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 20.0 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 20.0 |
| LRRC59 | leucine rich repeat containing 59 | 20.0 |
| TUBB4B | tubulin, beta 4B class IVb | 20.0 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 20.0 |
| MKI67 | marker of proliferation Ki-67 | 20.0 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 20.0 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 20.0 |
| STEAP2 | STEAP family member 2, metalloreductase | 20.0 |
| FNDC3A | fibronectin type III domain containing 3A | 20.0 |
| TTC5 | tetratricopeptide repeat domain 5 | 20.0 |
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D | 20.0 |
| C1S | complement component 1, s subcomponent | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| MAGED1 | melanoma antigen family D1 | 20.0 |
| TNS4 | tensin 4 | 20.0 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 20.0 |
| CCL5 | chemokine (C-C motif) ligand 5 | 20.0 |
| MCM7 | minichromosome maintenance complex component 7 | 20.0 |
| MRC2 | mannose receptor, C type 2 | 20.0 |
| CCND1 | cyclin D1 | 20.0 |
| CCND3 | cyclin D3 | 20.0 |
| HSPA4 | heat shock 70kDa protein 4 | 20.0 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 20.0 |
| STMN1 | stathmin 1 | 20.0 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 20.0 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 20.0 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 20.0 |
| GRAMD1B | GRAM domain containing 1B | 20.0 |
| CNTN1 | contactin 1 | 20.0 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 20.0 |
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 20.0 |
| MCM4 | minichromosome maintenance complex component 4 | 20.0 |
| MYRF | myelin regulatory factor | 20.0 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 20.0 |
| COL7A1 | collagen, type VII, alpha 1 | 20.0 |
| COL4A2 | collagen, type IV, alpha 2 | 20.0 |
| SMOC1 | SPARC related modular calcium binding 1 | 20.0 |
| NAMPT | nicotinamide phosphoribosyltransferase | 20.0 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 20.0 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 20.0 |
| MARS | methionyl-tRNA synthetase | 20.0 |
| VCAN | versican | 20.0 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 20.0 |
| ANKRD52 | ankyrin repeat domain 52 | 20.0 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 20.0 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 20.0 |
| RANGAP1 | Ran GTPase activating protein 1 | 20.0 |
| CBX6 | chromobox homolog 6 | 20.0 |
| USB1 | U6 snRNA biogenesis 1 | 20.0 |
| FASN | fatty acid synthase | 20.0 |
| HSPG2 | heparan sulfate proteoglycan 2 | 20.0 |
| LCN2 | lipocalin 2 | 20.0 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 20.0 |
| MYO15B | myosin XVB | 20.0 |
| FANCI | Fanconi anemia, complementation group I | 20.0 |
| STIP1 | stress-induced phosphoprotein 1 | 20.0 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 20.0 |
| GHITM | growth hormone inducible transmembrane protein | 20.0 |
| PCNA | proliferating cell nuclear antigen | 20.0 |
| ACACA | acetyl-CoA carboxylase alpha | 20.0 |
| HLA-A | major histocompatibility complex, class I, A | 20.0 |
| SLC25A39 | solute carrier family 25, member 39 | 20.0 |
| GPC1 | glypican 1 | 20.0 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 20.0 |
| CALU | calumenin | 20.0 |
| RAB27B | RAB27B, member RAS oncogene family | 20.0 |
| PCNXL3 | pecanex-like 3 (Drosophila) | 20.0 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 20.0 |
| MEGF8 | multiple EGF-like-domains 8 | 20.0 |
| SAE1 | SUMO1 activating enzyme subunit 1 | 20.0 |
| ANXA1 | annexin A1 | 20.0 |
| PYGB | phosphorylase, glycogen; brain | 20.0 |
| GCN1L1 | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 20.0 |
| KIF1C | kinesin family member 1C | 20.0 |
| PSAT1 | phosphoserine aminotransferase 1 | 20.0 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 20.0 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 20.0 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 20.0 |
| WARS | tryptophanyl-tRNA synthetase | 20.0 |
| IRF2BPL | interferon regulatory factor 2 binding protein-like | 20.0 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 20.0 |
| PLAU | plasminogen activator, urokinase | 20.0 |
| TXNIP | thioredoxin interacting protein | 20.0 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 20.0 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 20.0 |
| RPA1 | replication protein A1, 70kDa | 20.0 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 | 20.0 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 20.0 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 20.0 |
| TMPO | thymopoietin | 20.0 |
| PAQR5 | progestin and adipoQ receptor family member V | 20.0 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TBC1D22A | TBC1 domain family, member 22A | -20.0 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -20.0 |
| ATXN1 | ataxin 1 | -20.0 |
| PKD1L2 | polycystic kidney disease 1-like 2 (gene/pseudogene) | -20.0 |
| MUC1 | mucin 1, cell surface associated | -20.0 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -20.0 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -20.0 |
| FAM210A | family with sequence similarity 210, member A | -20.0 |
| IL4I1 | interleukin 4 induced 1 | -20.0 |
| LOX | lysyl oxidase | -20.0 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A | -20.0 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -20.0 |
| ATG14 | autophagy related 14 | -20.0 |
| MATR3 | matrin 3 | -20.0 |
| PER2 | period circadian clock 2 | -20.0 |
| WDR54 | WD repeat domain 54 | -20.0 |
| CA9 | carbonic anhydrase IX | -20.0 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -20.0 |
| RBM7 | RNA binding motif protein 7 | -20.0 |
| ALPK2 | alpha-kinase 2 | -20.0 |
| LBH | limb bud and heart development | -20.0 |
| CACNA1B | calcium channel, voltage-dependent, N type, alpha 1B subunit | -20.0 |
| CTGF | connective tissue growth factor | -20.0 |
| AGTPBP1 | ATP/GTP binding protein 1 | -20.0 |
| SEC61G | Sec61 gamma subunit | -20.0 |
| NKX3-1 | NK3 homeobox 1 | -20.0 |
| KAT6B | K(lysine) acetyltransferase 6B | -20.0 |
| KDM4C | lysine (K)-specific demethylase 4C | -20.0 |
| THBS1 | thrombospondin 1 | -20.0 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -20.0 |
| TMEM47 | transmembrane protein 47 | -20.0 |
| SH3D21 | SH3 domain containing 21 | -20.0 |
| DUSP8 | dual specificity phosphatase 8 | -20.0 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | -20.0 |
| PHF11 | PHD finger protein 11 | -20.0 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -20.0 |
| INSIG2 | insulin induced gene 2 | -20.0 |
| OPN3 | opsin 3 | -20.0 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -20.0 |
| AZI2 | 5-azacytidine induced 2 | -20.0 |
| SECTM1 | secreted and transmembrane 1 | -20.0 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -20.0 |
| SIM2 | single-minded family bHLH transcription factor 2 | -20.0 |
| TLR3 | toll-like receptor 3 | -20.0 |
| MOB3A | MOB kinase activator 3A | -20.0 |
| RSRP1 | arginine/serine-rich protein 1 | -20.0 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | -20.0 |
| BARX1 | BARX homeobox 1 | -20.0 |
| SPAG4 | sperm associated antigen 4 | -20.0 |
| LOC128125822 | uncharacterized LOC128125822 | -20.0 |
| UPK1A | uroplakin 1A | -20.0 |
| SLC45A1 | solute carrier family 45, member 1 | -20.0 |
| DRD1 | dopamine receptor D1 | -20.0 |
| C11ORF96 | chromosome 11 open reading frame 96 | -20.0 |
| DAPK3 | death-associated protein kinase 3 | -20.0 |
| EDN2 | endothelin 2 | -20.0 |
| C7ORF60 | chromosome 7 open reading frame 60 | -20.0 |
| ZNF703 | zinc finger protein 703 | -20.0 |
| RAB40C | RAB40C, member RAS oncogene family | -20.0 |
| RFX1 | regulatory factor X, 1 (influences HLA class II expression) | -20.0 |
| GAL3ST1 | galactose-3-O-sulfotransferase 1 | -20.0 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | -20.0 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | -20.0 |
| PLA1A | phospholipase A1 member A | -20.0 |
| FOXN3 | forkhead box N3 | -20.0 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -20.0 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -20.0 |
| RIMKLA | ribosomal modification protein rimK-like family member A | -20.0 |
| ATP10A | ATPase, class V, type 10A | -20.0 |
| DOCK7 | dedicator of cytokinesis 7 | -20.0 |
| THEMIS2 | thymocyte selection associated family member 2 | -20.0 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -20.0 |
| FBXO46 | F-box protein 46 | -20.0 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -20.0 |
| C8ORF58 | chromosome 8 open reading frame 58 | -20.0 |
| CLK4 | CDC-like kinase 4 | -20.0 |
| TET2 | tet methylcytosine dioxygenase 2 | -20.0 |
| ZFX | zinc finger protein, X-linked | -20.0 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -20.0 |
| TMEM184A | transmembrane protein 184A | -20.0 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) | -20.0 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -20.0 |
| PRDM1 | PR domain containing 1, with ZNF domain | -20.0 |
| DPYSL4 | dihydropyrimidinase-like 4 | -20.0 |
| CHML | choroideremia-like (Rab escort protein 2) | -20.0 |
| BMP6 | bone morphogenetic protein 6 | -20.0 |
| CLEC2B | C-type lectin domain family 2, member B | -20.0 |
| NLRP6 | NLR family, pyrin domain containing 6 | -20.0 |
| IL18BP | interleukin 18 binding protein | -20.0 |
| HSF4 | heat shock transcription factor 4 | -20.0 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 | -20.0 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -20.0 |
| IL1RAP | interleukin 1 receptor accessory protein | -20.0 |
| TBC1D25 | TBC1 domain family, member 25 | -20.0 |
| KCTD11 | potassium channel tetramerization domain containing 11 | -20.0 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -20.0 |
| TMEM45A | transmembrane protein 45A | -20.0 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -20.0 |
| POU5F1 | POU class 5 homeobox 1 | -20.0 |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 | -20.0 |