| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CNOT3 in CCRF-CEM cell line (Study accession: SRP117693) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_3212_KD_CNOT3_SRP117693 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 20.0 |
| EIF6 | eukaryotic translation initiation factor 6 | 20.0 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) | 20.0 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 20.0 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 20.0 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 20.0 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 20.0 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 20.0 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 20.0 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 20.0 |
| NOL7 | nucleolar protein 7, 27kDa | 20.0 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 20.0 |
| SAMM50 | SAMM50 sorting and assembly machinery component | 20.0 |
| ADRM1 | adhesion regulating molecule 1 | 20.0 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | 20.0 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 20.0 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 20.0 |
| CTPS1 | CTP synthase 1 | 20.0 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 20.0 |
| DRG1 | developmentally regulated GTP binding protein 1 | 20.0 |
| GTPBP4 | GTP binding protein 4 | 20.0 |
| PLK1 | polo-like kinase 1 | 20.0 |
| SRP68 | signal recognition particle 68kDa | 20.0 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 20.0 |
| SLBP | stem-loop binding protein | 20.0 |
| RCSD1 | RCSD domain containing 1 | 20.0 |
| NARS | asparaginyl-tRNA synthetase | 20.0 |
| MRFAP1 | Morf4 family associated protein 1 | 20.0 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase | 20.0 |
| UBXN1 | UBX domain protein 1 | 20.0 |
| HDGFRP2 | hepatoma-derived growth factor-related protein 2 | 20.0 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 20.0 |
| SMC3 | structural maintenance of chromosomes 3 | 20.0 |
| METAP2 | methionyl aminopeptidase 2 | 20.0 |
| HSPA8 | heat shock 70kDa protein 8 | 20.0 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | 20.0 |
| RTCB | RNA 2',3'-cyclic phosphate and 5'-OH ligase | 20.0 |
| CLTA | clathrin, light chain A | 20.0 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 20.0 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 20.0 |
| TBRG4 | transforming growth factor beta regulator 4 | 20.0 |
| MCM7 | minichromosome maintenance complex component 7 | 20.0 |
| MCM6 | minichromosome maintenance complex component 6 | 20.0 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | 20.0 |
| CCNB1 | cyclin B1 | 20.0 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 20.0 |
| ARFGAP2 | ADP-ribosylation factor GTPase activating protein 2 | 20.0 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 20.0 |
| TARS | threonyl-tRNA synthetase | 20.0 |
| EIF4B | eukaryotic translation initiation factor 4B | 20.0 |
| LYAR | Ly1 antibody reactive | 20.0 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 20.0 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa | 20.0 |
| XAB2 | XPA binding protein 2 | 20.0 |
| RARS | arginyl-tRNA synthetase | 20.0 |
| MRPS18B | mitochondrial ribosomal protein S18B | 20.0 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 | 20.0 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 20.0 |
| ABT1 | activator of basal transcription 1 | 20.0 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 20.0 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 20.0 |
| PFKP | phosphofructokinase, platelet | 20.0 |
| WDR3 | WD repeat domain 3 | 20.0 |
| SNW1 | SNW domain containing 1 | 20.0 |
| SAFB | scaffold attachment factor B | 20.0 |
| CCNA2 | cyclin A2 | 20.0 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 20.0 |
| ARCN1 | archain 1 | 20.0 |
| STIP1 | stress-induced phosphoprotein 1 | 20.0 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | 20.0 |
| RRP1 | ribosomal RNA processing 1 | 20.0 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) | 20.0 |
| RBM27 | RNA binding motif protein 27 | 20.0 |
| MRPL18 | mitochondrial ribosomal protein L18 | 20.0 |
| RSL1D1 | ribosomal L1 domain containing 1 | 20.0 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 20.0 |
| CDC20 | cell division cycle 20 | 20.0 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 20.0 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 20.0 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | 20.0 |
| RHOG | ras homolog family member G | 20.0 |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit | 20.0 |
| CCDC86 | coiled-coil domain containing 86 | 20.0 |
| DHX30 | DEAH (Asp-Glu-Ala-His) box helicase 30 | 20.0 |
| DHX37 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | 20.0 |
| MCMBP | minichromosome maintenance complex binding protein | 20.0 |
| GRSF1 | G-rich RNA sequence binding factor 1 | 20.0 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 20.0 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 20.0 |
| PLRG1 | pleiotropic regulator 1 | 20.0 |
| PNP | purine nucleoside phosphorylase | 20.0 |
| CDC5L | cell division cycle 5-like | 20.0 |
| NUP160 | nucleoporin 160kDa | 20.0 |
| LRRC47 | leucine rich repeat containing 47 | 20.0 |
| MRPS26 | mitochondrial ribosomal protein S26 | 20.0 |
| PRPF6 | pre-mRNA processing factor 6 | 20.0 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | 20.0 |
| NCAPH | non-SMC condensin I complex, subunit H | 20.0 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 20.0 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FKBP5 | FK506 binding protein 5 | -20.0 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -20.0 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -20.0 |
| RAB21 | RAB21, member RAS oncogene family | -20.0 |
| CANT1 | calcium activated nucleotidase 1 | -20.0 |
| BIRC5 | baculoviral IAP repeat containing 5 | -20.0 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -20.0 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -20.0 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 | -20.0 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -20.0 |
| RNF145 | ring finger protein 145 | -20.0 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -20.0 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -20.0 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -20.0 |
| FZD6 | frizzled class receptor 6 | -20.0 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -20.0 |
| ZBED1 | zinc finger, BED-type containing 1 | -20.0 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -20.0 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -20.0 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -20.0 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -20.0 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | -20.0 |
| SRPR | signal recognition particle receptor (docking protein) | -20.0 |
| TMEM30A | transmembrane protein 30A | -20.0 |
| MCM3 | minichromosome maintenance complex component 3 | -20.0 |
| BST2 | bone marrow stromal cell antigen 2 | -20.0 |
| RPN2 | ribophorin II | -20.0 |
| BZW1 | basic leucine zipper and W2 domains 1 | -20.0 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | -20.0 |
| RNF26 | ring finger protein 26 | -20.0 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -20.0 |
| SARAF | store-operated calcium entry-associated regulatory factor | -20.0 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -20.0 |
| KLF13 | Kruppel-like factor 13 | -20.0 |
| E2F2 | E2F transcription factor 2 | -20.0 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -20.0 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -20.0 |
| DESI1 | desumoylating isopeptidase 1 | -20.0 |
| NEK7 | NIMA-related kinase 7 | -20.0 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 | -20.0 |
| H2AFV | H2A histone family, member V | -20.0 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -20.0 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -20.0 |
| KLHL15 | kelch-like family member 15 | -20.0 |
| AZIN1 | antizyme inhibitor 1 | -20.0 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -20.0 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -20.0 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -20.0 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 | -20.0 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -20.0 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -20.0 |
| CALU | calumenin | -20.0 |
| AES | amino-terminal enhancer of split | -20.0 |
| MESDC1 | mesoderm development candidate 1 | -20.0 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -20.0 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 | -20.0 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -20.0 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -20.0 |
| PSAP | prosaposin | -20.0 |
| EXTL3 | exostosin-like glycosyltransferase 3 | -20.0 |
| CLIC4 | chloride intracellular channel 4 | -20.0 |
| IGF2R | insulin-like growth factor 2 receptor | -20.0 |
| UBL3 | ubiquitin-like 3 | -20.0 |
| CASC4 | cancer susceptibility candidate 4 | -20.0 |
| NAA20 | N(alpha)-acetyltransferase 20, NatB catalytic subunit | -20.0 |
| TFG | TRK-fused gene | -20.0 |
| ABI2 | abl-interactor 2 | -20.0 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -20.0 |
| FTL | ferritin, light polypeptide | -20.0 |
| SYPL1 | synaptophysin-like 1 | -20.0 |
| ATXN7L3 | ataxin 7-like 3 | -19.699 |
| BTBD3 | BTB (POZ) domain containing 3 | -19.699 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -19.1549 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -19.1549 |
| ZNF664 | zinc finger protein 664 | -18.9208 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -18.699 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -18.585 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -18.4815 |
| ITM2A | integral membrane protein 2A | -18.4685 |
| CHD3 | chromodomain helicase DNA binding protein 3 | -18.4437 |
| IMPAD1 | inositol monophosphatase domain containing 1 | -18.284 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -18.2596 |
| SP3 | Sp3 transcription factor | -18.2518 |
| C12ORF49 | chromosome 12 open reading frame 49 | -18.1739 |
| DYNLL2 | dynein, light chain, LC8-type 2 | -18.1135 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | -17.6271 |
| SKA3 | spindle and kinetochore associated complex subunit 3 | -17.3979 |
| DGCR2 | DiGeorge syndrome critical region gene 2 | -17.3958 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -17.1945 |
| SFT2D2 | SFT2 domain containing 2 | -17.1561 |
| PTMA | prothymosin, alpha | -17.0921 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -16.8486 |
| DHCR24 | 24-dehydrocholesterol reductase | -16.7897 |
| ELMSAN1 | ELM2 and Myb/SANT-like domain containing 1 | -16.6716 |
| CERS2 | ceramide synthase 2 | -16.4319 |
| SC5D | sterol-C5-desaturase | -16.2713 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -16.1153 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -16.0765 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | -15.9005 |
