Perturb_3879_KD_TMEM164_SRP333146 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting TMEM164 in colorectal adenocarcinoma cell SW480 cell line (Study accession: SRP333146) (PerturbAtlas)
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Genes

31 genes differentially expressed following the Perturb_3879_KD_TMEM164_SRP333146 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
VTI1B vesicle transport through interaction with t-SNAREs 1B 7.47087
HEATR1 HEAT repeat containing 1 3.84544
C5ORF45 chromosome 5 open reading frame 45 3.42738
TNRC6C trinucleotide repeat containing 6C 2.84608
PLTP phospholipid transfer protein 2.47215
H2AFY H2A histone family, member Y 2.29617
ERAP1 endoplasmic reticulum aminopeptidase 1 1.9118
DDA1 DET1 and DDB1 associated 1 1.78129
COG5 component of oligomeric golgi complex 5 1.715
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 1.37029

decreased expression

Symbol Name Standardized Value
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -6.29766
ENOSF1 enolase superfamily member 1 -4.45147
PAQR3 progestin and adipoQ receptor family member III -4.04313
GLRX5 glutaredoxin 5 -4.04313
UFSP2 UFM1-specific peptidase 2 -3.68496
PSMC3IP PSMC3 interacting protein -3.47178
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.83727
EME1 essential meiotic structure-specific endonuclease 1 -2.78539
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) -2.75264
LOC122455342 testis-specific serine/proline-rich protein -2.72518
SLA2 Src-like-adaptor 2 -2.41106
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -2.40371
RPAIN RPA interacting protein -2.40371
SREBF1 sterol regulatory element binding transcription factor 1 -2.08873
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -1.93979
PLLP plasmolipin -1.78129
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -1.78129
PAQR4 progestin and adipoQ receptor family member IV -1.78129
SLC25A35 solute carrier family 25, member 35 -1.69809
SNX22 sorting nexin 22 -1.34152
ERN2 endoplasmic reticulum to nucleus signaling 2 -1.33505