Perturb_3925_KD_VPS37C_SRP266781 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting VPS37C in colorectal cancer cell DLD-1 cell line (Study accession: SRP266781) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

31 genes differentially expressed following the Perturb_3925_KD_VPS37C_SRP266781 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 6.46873
PRR9 proline rich 9 6.16282
HMGA2 high mobility group AT-hook 2 3.36695
WDR1 WD repeat domain 1 3.23371
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 2.69855
INSIG1 insulin induced gene 1 2.27839
CREBZF CREB/ATF bZIP transcription factor 1.81833
TIMP3 TIMP metallopeptidase inhibitor 3 1.62402
GLUL glutamate-ammonia ligase 1.61532
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.55213
RCC2 regulator of chromosome condensation 2 1.34982

decreased expression

Symbol Name Standardized Value
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -14.5375
RRM2 ribonucleotide reductase M2 -6.46873
IGSF3 immunoglobulin superfamily, member 3 -5.39892
TCAF1 TRPM8 channel-associated factor 1 -4.5591
AAGAB alpha- and gamma-adaptin binding protein -4.53064
ZDHHC9 zinc finger, DHHC-type containing 9 -4.53064
NRARP NOTCH-regulated ankyrin repeat protein -4.40759
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 -4.31968
CLCC1 chloride channel CLIC-like 1 -3.94636
EPDR1 ependymin related 1 -3.64304
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.28449
TUFT1 tuftelin 1 -2.79776
USP22 ubiquitin specific peptidase 22 -2.75277
RWDD2B RWD domain containing 2B -2.71426
UBE2Z ubiquitin-conjugating enzyme E2Z -2.64954
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -2.06707
OSBPL1A oxysterol binding protein-like 1A -1.94605
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -1.57171
FXR1 fragile X mental retardation, autosomal homolog 1 -1.52061
RAD9A RAD9 homolog A (S. pombe) -1.41913