Perturb_407_OE_DPP4_SRP353826 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting DPP4 in A549 cell line (Study accession: SRP353826) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_407_OE_DPP4_SRP353826 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 20.0
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 20.0
PTMA prothymosin, alpha 20.0
LDHA lactate dehydrogenase A 20.0
NCL nucleolin 20.0
CLTC clathrin, heavy chain (Hc) 20.0
EEF2 eukaryotic translation elongation factor 2 20.0
RPS11 ribosomal protein S11 20.0
RPS16 ribosomal protein S16 20.0
RPS14 ribosomal protein S14 20.0
RPS19 ribosomal protein S19 20.0
ACTG1 actin gamma 1 20.0
CLU clusterin 20.0
AKR1C3 aldo-keto reductase family 1, member C3 20.0
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 20.0
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 20.0
ASPH aspartate beta-hydroxylase 20.0
RPL27A ribosomal protein L27a 20.0
RPL13A ribosomal protein L13a 20.0
RPLP1 ribosomal protein, large, P1 20.0
RPLP0 ribosomal protein, large, P0 20.0
DDR2 discoidin domain receptor tyrosine kinase 2 20.0
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 20.0
AKR1C2 aldo-keto reductase family 1, member C2 20.0
RPS18 ribosomal protein S18 20.0
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 20.0
RPS4X ribosomal protein S4, X-linked 20.0
RPS6 ribosomal protein S6 20.0
RPS5 ribosomal protein S5 20.0
RPS3 ribosomal protein S3 20.0
RPS2 ribosomal protein S2 20.0
RPS9 ribosomal protein S9 20.0
RPS8 ribosomal protein S8 20.0
RPSA ribosomal protein SA 20.0
RPL28 ribosomal protein L28 20.0
TPT1 tumor protein, translationally-controlled 1 20.0
HSPA8 heat shock 70kDa protein 8 20.0
HSPA9 heat shock 70kDa protein 9 (mortalin) 20.0
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 20.0
RPL15 ribosomal protein L15 20.0
RPL13 ribosomal protein L13 20.0
RPL18 ribosomal protein L18 20.0
RPL19 ribosomal protein L19 20.0
PGD phosphogluconate dehydrogenase 20.0
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 20.0
TUBB2A tubulin, beta 2A class IIa 20.0
PABPC1 poly(A) binding protein, cytoplasmic 1 20.0
TXNRD1 thioredoxin reductase 1 20.0
RPS27A ribosomal protein S27a 20.0
EIF4B eukaryotic translation initiation factor 4B 20.0
RPL12 ribosomal protein L12 20.0
PPIA peptidylprolyl isomerase A (cyclophilin A) 20.0
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 20.0
RAN RAN, member RAS oncogene family 20.0
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 20.0
RPS24 ribosomal protein S24 20.0
PGK1 phosphoglycerate kinase 1 20.0
FASN fatty acid synthase 20.0
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 20.0
RPL8 ribosomal protein L8 20.0
RPL4 ribosomal protein L4 20.0
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 20.0
RPL7A ribosomal protein L7a 20.0
TPI1 triosephosphate isomerase 1 20.0
ENO1 enolase 1, (alpha) 20.0
DKK1 dickkopf WNT signaling pathway inhibitor 1 20.0
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 20.0
FTL ferritin, light polypeptide 20.0
CPLX2 complexin 2 20.0
ACTN4 actinin, alpha 4 20.0
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 20.0
YBX1 Y box binding protein 1 20.0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 20.0
HSPD1 heat shock 60kDa protein 1 (chaperonin) 20.0
RPL5 ribosomal protein L5 20.0
RPL3 ribosomal protein L3 20.0
CANX calnexin 20.0
ACTB actin, beta 20.0
PKM pyruvate kinase, muscle 20.0
NONO non-POU domain containing, octamer-binding 20.0
ANXA1 annexin A1 20.0
ANXA2 annexin A2 20.0
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 20.0
TOP2A topoisomerase (DNA) II alpha 170kDa 20.0
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 20.0
G6PD glucose-6-phosphate dehydrogenase 20.0
NAP1L1 nucleosome assembly protein 1-like 1 20.0
TMSB10 thymosin beta 10 20.0
ACLY ATP citrate lyase 20.0
SCD stearoyl-CoA desaturase (delta-9-desaturase) 20.0
RPL7 ribosomal protein L7 20.0
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 20.0
FLNA filamin A, alpha 20.0
PSAP prosaposin 20.0
IGFBP4 insulin-like growth factor binding protein 4 20.0
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 20.0
PEG10 paternally expressed 10 20.0
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 20.0
KRT18 keratin 18, type I 20.0
NQO1 NAD(P)H dehydrogenase, quinone 1 20.0

decreased expression

Symbol Name Standardized Value
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -20.0
MUC6 mucin 6, oligomeric mucus/gel-forming -20.0
ASPDH aspartate dehydrogenase domain containing -20.0
CHRNG cholinergic receptor, nicotinic, gamma (muscle) -20.0
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -20.0
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B -20.0
CYB5R2 cytochrome b5 reductase 2 -20.0
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -20.0
LINC00514 long intergenic non-protein coding RNA 514 -20.0
ECT2L epithelial cell transforming 2 like -20.0
PVRIG poliovirus receptor related immunoglobulin domain containing -20.0
C17ORF50 chromosome 17 open reading frame 50 -20.0
SGPP2 sphingosine-1-phosphate phosphatase 2 -20.0
GJB5 gap junction protein, beta 5, 31.1kDa -20.0
S100A5 S100 calcium binding protein A5 -20.0
C8ORF74 chromosome 8 open reading frame 74 -20.0
ZBTB32 zinc finger and BTB domain containing 32 -20.0
SMIM5 small integral membrane protein 5 -20.0
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) -20.0
TDRD6 tudor domain containing 6 -20.0
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 -20.0
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -20.0
DET1 de-etiolated homolog 1 (Arabidopsis) -20.0
FN3K fructosamine 3 kinase -20.0
LIPC lipase, hepatic -20.0
TUBA3D tubulin, alpha 3d -20.0
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -20.0
GPM6B glycoprotein M6B -20.0
TTC23L tetratricopeptide repeat domain 23-like -20.0
RGMA repulsive guidance molecule family member a -20.0
LDB3 LIM domain binding 3 -20.0
GPR34 G protein-coupled receptor 34 -20.0
GRAMD2 GRAM domain containing 2 -20.0
YPEL4 yippee-like 4 (Drosophila) -20.0
FAM13C family with sequence similarity 13, member C -20.0
CES4A carboxylesterase 4A -20.0
SYT13 synaptotagmin XIII -20.0
FBXO24 F-box protein 24 -20.0
PCDHGC3 protocadherin gamma subfamily C, 3 -20.0
C4ORF19 chromosome 4 open reading frame 19 -20.0
ACMSD aminocarboxymuconate semialdehyde decarboxylase -20.0
OR7C1 olfactory receptor, family 7, subfamily C, member 1 -20.0
NPNT nephronectin -20.0
CFAP43 cilia and flagella associated protein 43 -20.0
SPARCL1 SPARC-like 1 (hevin) -20.0
TACR2 tachykinin receptor 2 -20.0
LOC100506374 uncharacterized LOC100506374 -20.0
BLNK B-cell linker -20.0
TAS1R3 taste receptor, type 1, member 3 -20.0
VCAN versican -20.0
PHACTR1 phosphatase and actin regulator 1 -20.0
LRRC19 leucine rich repeat containing 19 -20.0
PRPH peripherin -20.0
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -20.0
CCDC181 coiled-coil domain containing 181 -20.0
LMOD1 leiomodin 1 (smooth muscle) -20.0
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 -20.0
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) -20.0
TBC1D10C TBC1 domain family, member 10C -20.0
ZNF785 zinc finger protein 785 -20.0
ARR3 arrestin 3, retinal (X-arrestin) -20.0
PEX5L peroxisomal biogenesis factor 5-like -20.0
LRRC7 leucine rich repeat containing 7 -20.0
PLAC9 placenta-specific 9 -20.0
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 -20.0
HOXA11 homeobox A11 -20.0
NKAIN4 Na+/K+ transporting ATPase interacting 4 -20.0
UNC5C unc-5 homolog C (C. elegans) -20.0
C11ORF42 chromosome 11 open reading frame 42 -20.0
INSL3 insulin-like 3 (Leydig cell) -20.0
KCTD19 potassium channel tetramerization domain containing 19 -20.0
CYTH4 cytohesin 4 -20.0
FAT2 FAT atypical cadherin 2 -20.0
HOXA7 homeobox A7 -20.0
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -20.0
NPY4R neuropeptide Y receptor Y4 -20.0
GRIK1 glutamate receptor, ionotropic, kainate 1 -20.0
CD101 CD101 molecule -20.0
VIPR2 vasoactive intestinal peptide receptor 2 -20.0
FILIP1 filamin A interacting protein 1 -20.0
CYSRT1 cysteine-rich tail protein 1 -20.0
PLA2G10 phospholipase A2, group X -20.0
CFAP57 cilia and flagella associated protein 57 -20.0
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 -20.0
MYO1H myosin IH -20.0
ZNF154 zinc finger protein 154 -20.0
TMEM45B transmembrane protein 45B -20.0
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -20.0
FGF14 fibroblast growth factor 14 -20.0
ERICH6 glutamate-rich 6 -20.0
LOC100129216 beta-defensin 131-like -20.0
ZNF57 zinc finger protein 57 -20.0
TMEM74B transmembrane protein 74B -20.0
SARNP SAP domain containing ribonucleoprotein -20.0
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -20.0
EIF4E3 eukaryotic translation initiation factor 4E family member 3 -20.0
EPX eosinophil peroxidase -20.0
MMP9 matrix metallopeptidase 9 -20.0
MMP7 matrix metallopeptidase 7 -20.0
ABI3BP ABI family, member 3 (NESH) binding protein -20.0