| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting MYBL2 in A549 cell line (Study accession: SRP239534) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_421_KD_MYBL2_SRP239534 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) | 20.0 |
| SPRED3 | sprouty-related, EVH1 domain containing 3 | 20.0 |
| ADGRB2 | adhesion G protein-coupled receptor B2 | 20.0 |
| FAM131B | family with sequence similarity 131, member B | 20.0 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 | 20.0 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 | 20.0 |
| TMEM59L | transmembrane protein 59-like | 20.0 |
| RAB39B | RAB39B, member RAS oncogene family | 20.0 |
| ABAT | 4-aminobutyrate aminotransferase | 20.0 |
| DAPK2 | death-associated protein kinase 2 | 19.3979 |
| DENND2A | DENN/MADD domain containing 2A | 17.6498 |
| SPTB | spectrin, beta, erythrocytic | 17.2147 |
| LOC728392 | uncharacterized LOC728392 | 17.1349 |
| RHPN1 | rhophilin, Rho GTPase binding protein 1 | 16.0643 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 15.6766 |
| SYNGR3 | synaptogyrin 3 | 15.2205 |
| GIPR | gastric inhibitory polypeptide receptor | 15.1412 |
| TMEM130 | transmembrane protein 130 | 15.0962 |
| MAP6 | microtubule-associated protein 6 | 14.9818 |
| CEND1 | cell cycle exit and neuronal differentiation 1 | 14.2054 |
| NOVA2 | neuro-oncological ventral antigen 2 | 14.1868 |
| LAT2 | linker for activation of T cells family, member 2 | 13.9771 |
| CD82 | CD82 molecule | 13.6302 |
| QPCT | glutaminyl-peptide cyclotransferase | 13.6302 |
| KIF7 | kinesin family member 7 | 13.5256 |
| CRLF2 | cytokine receptor-like factor 2 | 13.28 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 13.0136 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 12.5271 |
| KIRREL2 | kin of IRRE like 2 (Drosophila) | 12.4884 |
| SYT11 | synaptotagmin XI | 12.2582 |
| ABHD4 | abhydrolase domain containing 4 | 12.1463 |
| KLK1 | kallikrein 1 | 11.493 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 11.4573 |
| GCK | glucokinase (hexokinase 4) | 11.4457 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 11.4322 |
| SNCB | synuclein, beta | 11.3983 |
| NECAP1 | NECAP endocytosis associated 1 | 11.3103 |
| TMOD2 | tropomodulin 2 (neuronal) | 11.2718 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 11.158 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 11.0767 |
| KIF5C | kinesin family member 5C | 10.9905 |
| TMEM98 | transmembrane protein 98 | 10.7801 |
| RGAG4 | retrotransposon gag domain containing 4 | 10.7715 |
| EBI3 | Epstein-Barr virus induced 3 | 10.6273 |
| PPM1K | protein phosphatase, Mg2+/Mn2+ dependent, 1K | 10.4833 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 | 10.4662 |
| EGF | epidermal growth factor | 10.4214 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 10.2374 |
| CCDC136 | coiled-coil domain containing 136 | 10.0405 |
| ANKRD46 | ankyrin repeat domain 46 | 9.99915 |
| MARCH9 | membrane-associated ring finger (C3HC4) 9 | 9.91372 |
| BTG2 | BTG family, member 2 | 9.76161 |
| ELOVL4 | ELOVL fatty acid elongase 4 | 9.60897 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 9.40051 |
| CBX7 | chromobox homolog 7 | 9.34903 |
| S100G | S100 calcium binding protein G | 9.17692 |
| SAMD14 | sterile alpha motif domain containing 14 | 9.04744 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | 8.7576 |
| DYNLL2 | dynein, light chain, LC8-type 2 | 8.64681 |
| MR1 | major histocompatibility complex, class I-related | 8.57611 |
| ANO9 | anoctamin 9 | 8.42895 |
| DGKA | diacylglycerol kinase, alpha 80kDa | 8.37702 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | 8.31732 |
| WNK4 | WNK lysine deficient protein kinase 4 | 8.29623 |
| LRRC4B | leucine rich repeat containing 4B | 8.27215 |
| TMEM229B | transmembrane protein 229B | 8.25443 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | 8.21409 |
| TBC1D2B | TBC1 domain family, member 2B | 8.17855 |
| ANKRD24 | ankyrin repeat domain 24 | 8.15215 |
| CNTNAP1 | contactin associated protein 1 | 8.13751 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 | 8.07797 |
| JAM3 | junctional adhesion molecule 3 | 8.07646 |
| TRO | trophinin | 7.76702 |
| NACAD | NAC alpha domain containing | 7.67621 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 7.67211 |
| ZMAT3 | zinc finger, matrin-type 3 | 7.6351 |
| PLAT | plasminogen activator, tissue | 7.62379 |
| RND1 | Rho family GTPase 1 | 7.62379 |
| HPCAL4 | hippocalcin like 4 | 7.61086 |
| VPS25 | vacuolar protein sorting 25 homolog (S. cerevisiae) | 7.3814 |
| ETNK2 | ethanolamine kinase 2 | 7.36281 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | 7.325 |
| TMEM55A | transmembrane protein 55A | 7.29991 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 7.28863 |
| GFAP | glial fibrillary acidic protein | 7.28454 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 7.24118 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 7.20877 |
| PRRT3 | proline-rich transmembrane protein 3 | 7.17312 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase | 7.09249 |
| TMEM86A | transmembrane protein 86A | 7.04567 |
| LMBR1L | limb development membrane protein 1-like | 6.93078 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 6.92012 |
| GPR162 | G protein-coupled receptor 162 | 6.84751 |
| CGN | cingulin | 6.81205 |
| JUNB | jun B proto-oncogene | 6.7334 |
| SAMD9 | sterile alpha motif domain containing 9 | 6.71937 |
| TMEM26 | transmembrane protein 26 | 6.6665 |
| SELT | selenoprotein T | 6.65111 |
| GGT7 | gamma-glutamyltransferase 7 | 6.6189 |
| FRY | furry homolog (Drosophila) | 6.60622 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF768 | zinc finger protein 768 | -20.0 |
| MIA3 | melanoma inhibitory activity family, member 3 | -20.0 |
| EHD2 | EH-domain containing 2 | -20.0 |
| H1F0 | H1 histone family, member 0 | -20.0 |
| POM121C | POM121 transmembrane nucleoporin C | -20.0 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -20.0 |
| VANGL1 | VANGL planar cell polarity protein 1 | -20.0 |
| SAPCD2 | suppressor APC domain containing 2 | -20.0 |
| EXTL3 | exostosin-like glycosyltransferase 3 | -20.0 |
| IMMT | inner membrane protein, mitochondrial | -20.0 |
| MCM9 | minichromosome maintenance complex component 9 | -20.0 |
| ASPH | aspartate beta-hydroxylase | -20.0 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -20.0 |
| ZNF765 | zinc finger protein 765 | -20.0 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | -20.0 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -20.0 |
| RCC2 | regulator of chromosome condensation 2 | -20.0 |
| LAMP1 | lysosomal-associated membrane protein 1 | -20.0 |
| TSHZ1 | teashirt zinc finger homeobox 1 | -20.0 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | -20.0 |
| PUM1 | pumilio RNA-binding family member 1 | -20.0 |
| MYO1C | myosin IC | -20.0 |
| POM121 | POM121 transmembrane nucleoporin | -20.0 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -20.0 |
| DAP | death-associated protein | -20.0 |
| JARID2 | jumonji, AT rich interactive domain 2 | -20.0 |
| PRR14 | proline rich 14 | -20.0 |
| NGRN | neugrin, neurite outgrowth associated | -20.0 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -20.0 |
| TSPAN9 | tetraspanin 9 | -20.0 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -20.0 |
| OTUD4 | OTU deubiquitinase 4 | -20.0 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -20.0 |
| ZNF766 | zinc finger protein 766 | -20.0 |
| REXO1 | REX1, RNA exonuclease 1 homolog (S. cerevisiae) | -20.0 |
| SLAIN2 | SLAIN motif family, member 2 | -20.0 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -20.0 |
| THUMPD1 | THUMP domain containing 1 | -20.0 |
| CERK | ceramide kinase | -20.0 |
| PCBP4 | poly(rC) binding protein 4 | -20.0 |
| FAM168B | family with sequence similarity 168, member B | -20.0 |
| CEL | carboxyl ester lipase | -20.0 |
| ZNF845 | zinc finger protein 845 | -19.699 |
| RRBP1 | ribosome binding protein 1 | -19.3979 |
| SOCS6 | suppressor of cytokine signaling 6 | -19.301 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -18.7696 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -18.6778 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -18.585 |
| MED14 | mediator complex subunit 14 | -18.1024 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | -17.9747 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -17.9547 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 | -17.8827 |
| FBXW5 | F-box and WD repeat domain containing 5 | -17.6364 |
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | -17.3726 |
| MTX3 | metaxin 3 | -17.2832 |
| FAM168A | family with sequence similarity 168, member A | -17.2596 |
| NUMB | numb homolog (Drosophila) | -17.1107 |
| SLC2A4RG | SLC2A4 regulator | -17.1096 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -17.0506 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | -16.9439 |
| LRFN1 | leucine rich repeat and fibronectin type III domain containing 1 | -16.8633 |
| SHISA5 | shisa family member 5 | -16.7849 |
| CENPA | centromere protein A | -16.6068 |
| TSPAN14 | tetraspanin 14 | -16.6068 |
| ADPGK | ADP-dependent glucokinase | -16.5952 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | -16.4609 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -16.4274 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | -16.4244 |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) | -16.3372 |
| CENPE | centromere protein E, 312kDa | -16.3372 |
| F2R | coagulation factor II (thrombin) receptor | -16.3179 |
| FAM122B | family with sequence similarity 122B | -16.2233 |
| PHF6 | PHD finger protein 6 | -16.175 |
| TBC1D13 | TBC1 domain family, member 13 | -16.0393 |
| PRR12 | proline rich 12 | -15.9563 |
| JMJD6 | jumonji domain containing 6 | -15.9559 |
| COG2 | component of oligomeric golgi complex 2 | -15.8419 |
| HLTF | helicase-like transcription factor | -15.7877 |
| ABHD2 | abhydrolase domain containing 2 | -15.7415 |
| USF2 | upstream transcription factor 2, c-fos interacting | -15.7324 |
| GLRX5 | glutaredoxin 5 | -15.713 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -15.5887 |
| ZNF480 | zinc finger protein 480 | -15.5446 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -15.3854 |
| MED16 | mediator complex subunit 16 | -15.2872 |
| DEPDC1B | DEP domain containing 1B | -15.2039 |
| FAM120A | family with sequence similarity 120A | -15.1787 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -15.1412 |
| MXD3 | MAX dimerization protein 3 | -15.0409 |
| MAP1S | microtubule-associated protein 1S | -14.9993 |
| CYB5R3 | cytochrome b5 reductase 3 | -14.8285 |
| MTA1 | metastasis associated 1 | -14.7508 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -14.7102 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -14.6711 |
| RSPRY1 | ring finger and SPRY domain containing 1 | -14.6148 |
| POGK | pogo transposable element with KRAB domain | -14.5519 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -14.5026 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -14.4843 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -14.2474 |
| MFAP3L | microfibrillar-associated protein 3-like | -14.1868 |
