Perturb_4347_OE_LEF1_SRP165165 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting LEF1 in dermal papilla cells cell (Study accession: SRP165165) (PerturbAtlas)
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Genes

34 genes differentially expressed following the Perturb_4347_OE_LEF1_SRP165165 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
OR2I1P olfactory receptor, family 2, subfamily I, member 1 pseudogene 4.87263
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 4.69284
CCR7 chemokine (C-C motif) receptor 7 4.00185
MESDC2 mesoderm development candidate 2 3.35914
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.35914
STC1 stanniocalcin 1 3.35914
DPH1 diphthamide biosynthesis 1 3.03348
PECAM1 platelet/endothelial cell adhesion molecule 1 2.7424
SIX5 SIX homeobox 5 2.60692
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 1.81901
TYMS thymidylate synthetase 1.62321
TBC1D17 TBC1 domain family, member 17 1.61754
CACFD1 calcium channel flower domain containing 1 1.57557
RWDD2A RWD domain containing 2A 1.57557
FMNL1 formin-like 1 1.57557
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.48873
PUS10 pseudouridylate synthase 10 1.48873
HPS4 Hermansky-Pudlak syndrome 4 1.44549
ZBTB38 zinc finger and BTB domain containing 38 1.41834
SPIDR scaffolding protein involved in DNA repair 1.41834
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.32062

decreased expression

Symbol Name Standardized Value
PCSK7 proprotein convertase subtilisin/kexin type 7 -3.03348
HAS2 hyaluronan synthase 2 -3.03348
RGMB repulsive guidance molecule family member b -1.86546
PLD4 phospholipase D family, member 4 -1.86546
CCDC85B coiled-coil domain containing 85B -1.82147
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -1.43558
FMN2 formin 2 -1.43558
WDR20 WD repeat domain 20 -1.37102
PAQR4 progestin and adipoQ receptor family member IV -1.336
PDGFC platelet derived growth factor C -1.336
C11ORF68 chromosome 11 open reading frame 68 -1.32436
IQGAP2 IQ motif containing GTPase activating protein 2 -1.32062
GPR39 G protein-coupled receptor 39 -1.30492