| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SUV39H1 in diffuse large B-cell lymphoma U937 cell line (Study accession: SRP290196) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_4396_KD_SUV39H1_SRP290196 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SUMF2 | sulfatase modifying factor 2 | 20.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | 20.0 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 20.0 |
| SQSTM1 | sequestosome 1 | 20.0 |
| FAM129A | family with sequence similarity 129, member A | 20.0 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 20.0 |
| PLIN2 | perilipin 2 | 20.0 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 20.0 |
| RNF213 | ring finger protein 213 | 20.0 |
| PLEC | plectin | 20.0 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 20.0 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 | 20.0 |
| DICER1 | dicer 1, ribonuclease type III | 20.0 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 20.0 |
| GRN | granulin | 20.0 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 20.0 |
| MYO1G | myosin IG | 20.0 |
| MYO1F | myosin IF | 20.0 |
| IFI6 | interferon, alpha-inducible protein 6 | 20.0 |
| NKTR | natural killer cell triggering receptor | 20.0 |
| GTPBP2 | GTP binding protein 2 | 20.0 |
| MROH1 | maestro heat-like repeat family member 1 | 20.0 |
| NISCH | nischarin | 20.0 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 20.0 |
| NCSTN | nicastrin | 20.0 |
| AHNAK | AHNAK nucleoprotein | 20.0 |
| C3 | complement component 3 | 20.0 |
| DENND3 | DENN/MADD domain containing 3 | 20.0 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 20.0 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 20.0 |
| MRC2 | mannose receptor, C type 2 | 20.0 |
| SH3BP2 | SH3-domain binding protein 2 | 20.0 |
| TAPBP | TAP binding protein (tapasin) | 20.0 |
| CCNL2 | cyclin L2 | 20.0 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 20.0 |
| NADK | NAD kinase | 20.0 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 20.0 |
| RASAL3 | RAS protein activator like 3 | 20.0 |
| RNF24 | ring finger protein 24 | 20.0 |
| RAB44 | RAB44, member RAS oncogene family | 20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 20.0 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 20.0 |
| GIGYF1 | GRB10 interacting GYF protein 1 | 20.0 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 20.0 |
| GUSB | glucuronidase, beta | 20.0 |
| CUL9 | cullin 9 | 20.0 |
| ARHGAP4 | Rho GTPase activating protein 4 | 20.0 |
| ANLN | anillin, actin binding protein | 20.0 |
| DMXL2 | Dmx-like 2 | 20.0 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 20.0 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 20.0 |
| FAM111A | family with sequence similarity 111, member A | 20.0 |
| AARS | alanyl-tRNA synthetase | 20.0 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit | 20.0 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 20.0 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase | 20.0 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 20.0 |
| SKI | SKI proto-oncogene | 20.0 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 20.0 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 20.0 |
| ADAM9 | ADAM metallopeptidase domain 9 | 20.0 |
| COL9A2 | collagen, type IX, alpha 2 | 20.0 |
| PLD3 | phospholipase D family, member 3 | 20.0 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| NPC2 | Niemann-Pick disease, type C2 | 20.0 |
| HLA-B | major histocompatibility complex, class I, B | 20.0 |
| HLA-A | major histocompatibility complex, class I, A | 20.0 |
| NOTCH2 | notch 2 | 20.0 |
| EFCAB14 | EF-hand calcium binding domain 14 | 20.0 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 20.0 |
| CTSD | cathepsin D | 20.0 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 20.0 |
| LYZ | lysozyme | 20.0 |
| TADA2A | transcriptional adaptor 2A | 20.0 |
| B2M | beta-2-microglobulin | 20.0 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 20.0 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | 20.0 |
| GPNMB | glycoprotein (transmembrane) nmb | 20.0 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 20.0 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | 20.0 |
| AZU1 | azurocidin 1 | 20.0 |
| PSAT1 | phosphoserine aminotransferase 1 | 20.0 |
| VEGFA | vascular endothelial growth factor A | 20.0 |
| MYO9B | myosin IXB | 20.0 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | 20.0 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 20.0 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 | 20.0 |
| RAB8B | RAB8B, member RAS oncogene family | 20.0 |
| PSAP | prosaposin | 20.0 |
| DENND4B | DENN/MADD domain containing 4B | 20.0 |
| CLIC4 | chloride intracellular channel 4 | 20.0 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 20.0 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 20.0 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 20.0 |
| IFI16 | interferon, gamma-inducible protein 16 | 20.0 |
| SUN2 | Sad1 and UNC84 domain containing 2 | 20.0 |
| HLA-C | major histocompatibility complex, class I, C | 20.0 |
| HLA-E | major histocompatibility complex, class I, E | 20.0 |
| NBEAL2 | neurobeachin-like 2 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PITX3 | paired-like homeodomain 3 | -20.0 |
| RPL26L1 | ribosomal protein L26-like 1 | -20.0 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -20.0 |
| EML1 | echinoderm microtubule associated protein like 1 | -20.0 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) | -20.0 |
| AVEN | apoptosis, caspase activation inhibitor | -20.0 |
| LMO1 | LIM domain only 1 (rhombotin 1) | -20.0 |
| MRPL54 | mitochondrial ribosomal protein L54 | -20.0 |
| MREG | melanoregulin | -20.0 |
| TERT | telomerase reverse transcriptase | -20.0 |
| HRSP12 | heat-responsive protein 12 | -20.0 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 | -20.0 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -20.0 |
| FERMT1 | fermitin family member 1 | -20.0 |
| PITX1 | paired-like homeodomain 1 | -20.0 |
| ANXA2R | annexin A2 receptor | -20.0 |
| FAM81A | family with sequence similarity 81, member A | -20.0 |
| CLCN2 | chloride channel, voltage-sensitive 2 | -20.0 |
| MRPL23 | mitochondrial ribosomal protein L23 | -20.0 |
| IL2RB | interleukin 2 receptor, beta | -20.0 |
| TBC1D4 | TBC1 domain family, member 4 | -20.0 |
| COQ3 | coenzyme Q3 methyltransferase | -20.0 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | -20.0 |
| CCNE1 | cyclin E1 | -20.0 |
| THAP4 | THAP domain containing 4 | -20.0 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -20.0 |
| ANAPC15 | anaphase promoting complex subunit 15 | -20.0 |
| DTD1 | D-tyrosyl-tRNA deacylase 1 | -20.0 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like | -20.0 |
| TSPAN5 | tetraspanin 5 | -20.0 |
| L3MBTL3 | l(3)mbt-like 3 (Drosophila) | -20.0 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -20.0 |
| TMEM261 | transmembrane protein 261 | -20.0 |
| SHROOM2 | shroom family member 2 | -20.0 |
| DUSP2 | dual specificity phosphatase 2 | -20.0 |
| BEND3 | BEN domain containing 3 | -20.0 |
| CD3EAP | CD3e molecule, epsilon associated protein | -20.0 |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) | -20.0 |
| PRR7 | proline rich 7 (synaptic) | -20.0 |
| LYRM1 | LYR motif containing 1 | -20.0 |
| ZNF584 | zinc finger protein 584 | -20.0 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | -20.0 |
| NKRF | NFKB repressing factor | -20.0 |
| E2F5 | E2F transcription factor 5, p130-binding | -20.0 |
| C3ORF80 | chromosome 3 open reading frame 80 | -20.0 |
| GOLGA7B | golgin A7 family, member B | -20.0 |
| SLAMF8 | SLAM family member 8 | -20.0 |
| RUNX2 | runt-related transcription factor 2 | -20.0 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -20.0 |
| LOC124902392 | uncharacterized LOC124902392 | -20.0 |
| ART3 | ADP-ribosyltransferase 3 | -20.0 |
| PINX1 | PIN2/TERF1 interacting, telomerase inhibitor 1 | -20.0 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -20.0 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | -20.0 |
| PAGE1 | P antigen family, member 1 (prostate associated) | -20.0 |
| NEGR1 | neuronal growth regulator 1 | -20.0 |
| FXN | frataxin | -20.0 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -20.0 |
| WFDC1 | WAP four-disulfide core domain 1 | -20.0 |
| C1ORF233 | chromosome 1 open reading frame 233 | -20.0 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | -20.0 |
| ALKBH2 | alkB, alkylation repair homolog 2 (E. coli) | -20.0 |
| GRIN3A | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A | -20.0 |
| MRPL12 | mitochondrial ribosomal protein L12 | -20.0 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -20.0 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -20.0 |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) | -20.0 |
| SPATA13 | spermatogenesis associated 13 | -20.0 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -20.0 |
| HIST1H1C | histone cluster 1, H1c | -20.0 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -20.0 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | -20.0 |
| RASL11A | RAS-like, family 11, member A | -20.0 |
| CTXN1 | cortexin 1 | -20.0 |
| SCFD2 | sec1 family domain containing 2 | -20.0 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -20.0 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -20.0 |
| FRMPD2 | FERM and PDZ domain containing 2 | -20.0 |
| LINC00094 | long intergenic non-protein coding RNA 94 | -20.0 |
| CBR1 | carbonyl reductase 1 | -20.0 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B | -20.0 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -20.0 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | -20.0 |
| DMWD | dystrophia myotonica, WD repeat containing | -20.0 |
| NLRP7 | NLR family, pyrin domain containing 7 | -20.0 |
| TRIM71 | tripartite motif containing 71, E3 ubiquitin protein ligase | -20.0 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -20.0 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 | -20.0 |
| EXOSC4 | exosome component 4 | -20.0 |
| RGS16 | regulator of G-protein signaling 16 | -20.0 |
| PMM2 | phosphomannomutase 2 | -20.0 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -20.0 |
| KRT9 | keratin 9, type I | -20.0 |
| CBWD2 | COBW domain containing 2 | -20.0 |
| CBWD1 | COBW domain containing 1 | -20.0 |
| ECE2 | endothelin converting enzyme 2 | -20.0 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | -20.0 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | -20.0 |
| ENDOD1 | endonuclease domain containing 1 | -20.0 |
| TCF4 | transcription factor 4 | -20.0 |
