| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ADAR2 in A549 cell line (Study accession: SRP253895) (PerturbAtlas) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perturb_468_KD_ADAR2_SRP253895 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC85B | coiled-coil domain containing 85B | 20.0 |
| HOOK2 | hook microtubule-tethering protein 2 | 20.0 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 20.0 |
| SLC46A1 | solute carrier family 46 (folate transporter), member 1 | 20.0 |
| EPHA1 | EPH receptor A1 | 20.0 |
| HIST1H4I | histone cluster 1, H4i | 18.4949 |
| IAH1 | isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) | 16.8072 |
| KRT17 | keratin 17, type I | 16.2188 |
| FAS | Fas cell surface death receptor | 16.0212 |
| TMEM184A | transmembrane protein 184A | 14.1042 |
| ARHGAP5 | Rho GTPase activating protein 5 | 14.0904 |
| TMEM79 | transmembrane protein 79 | 13.68 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 13.6506 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 13.6148 |
| RPL10 | ribosomal protein L10 | 13.3116 |
| PCED1B | PC-esterase domain containing 1B | 12.594 |
| TMEM120B | transmembrane protein 120B | 12.5227 |
| WDR33 | WD repeat domain 33 | 11.7049 |
| TMEM258 | transmembrane protein 258 | 10.8657 |
| MMP24-AS1 | MMP24 antisense RNA 1 | 10.3612 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) | 10.0429 |
| BCCIP | BRCA2 and CDKN1A interacting protein | 9.87978 |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase | 9.43384 |
| RHOBTB2 | Rho-related BTB domain containing 2 | 9.37307 |
| SLC5A10 | solute carrier family 5 (sodium/sugar cotransporter), member 10 | 9.06989 |
| CIDEB | cell death-inducing DFFA-like effector b | 9.00134 |
| GRIP2 | glutamate receptor interacting protein 2 | 8.80218 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | 8.27143 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 8.09752 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 7.92026 |
| TUBA1C | tubulin, alpha 1c | 7.78593 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 7.73133 |
| NPBWR1 | neuropeptides B/W receptor 1 | 7.68924 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 7.61969 |
| SDR39U1 | short chain dehydrogenase/reductase family 39U, member 1 | 7.5007 |
| BCAN | brevican | 7.49536 |
| SPATA6L | spermatogenesis associated 6-like | 7.2349 |
| UBXN11 | UBX domain protein 11 | 7.15727 |
| NME7 | NME/NM23 family member 7 | 7.11114 |
| RBBP4 | retinoblastoma binding protein 4 | 7.09845 |
| CRTAC1 | cartilage acidic protein 1 | 6.5739 |
| MLPH | melanophilin | 6.54724 |
| UROD | uroporphyrinogen decarboxylase | 6.23422 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | 6.18292 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | 6.00608 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | 5.97933 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 | 5.88875 |
| ZNF517 | zinc finger protein 517 | 5.86729 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 5.85217 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 5.7168 |
| FKBP15 | FK506 binding protein 15, 133kDa | 5.69122 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 5.60811 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 | 5.35585 |
| WBSCR22 | Williams Beuren syndrome chromosome region 22 | 5.32174 |
| DENND1C | DENN/MADD domain containing 1C | 5.31728 |
| MRPL43 | mitochondrial ribosomal protein L43 | 5.29277 |
| KLC4 | kinesin light chain 4 | 5.2616 |
| FANCI | Fanconi anemia, complementation group I | 5.24057 |
| SAV1 | salvador family WW domain containing protein 1 | 5.03374 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 5.01313 |
| EML2 | echinoderm microtubule associated protein like 2 | 4.97084 |
| C14ORF166 | chromosome 14 open reading frame 166 | 4.9684 |
| ANKRD37 | ankyrin repeat domain 37 | 4.91159 |
| FBXO44 | F-box protein 44 | 4.87576 |
| PLTP | phospholipid transfer protein | 4.86866 |
| SLC12A9 | solute carrier family 12, member 9 | 4.79761 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 4.60643 |
| C8ORF59 | chromosome 8 open reading frame 59 | 4.55128 |
| KRT8 | keratin 8, type II | 4.53814 |
| MTCL1 | microtubule crosslinking factor 1 | 4.52631 |
| ENO3 | enolase 3 (beta, muscle) | 4.47123 |
| FAM227B | family with sequence similarity 227, member B | 4.44544 |
| FAM71E1 | family with sequence similarity 71, member E1 | 4.36984 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 4.29623 |
| CDC14B | cell division cycle 14B | 4.26382 |
| LOC128125822 | uncharacterized LOC128125822 | 4.25661 |
| CCDC18 | coiled-coil domain containing 18 | 4.24103 |
| SPATA21 | spermatogenesis associated 21 | 4.22238 |
| C12ORF43 | chromosome 12 open reading frame 43 | 4.18577 |
| ARG2 | arginase 2 | 4.17083 |
| FBXL6 | F-box and leucine-rich repeat protein 6 | 4.16355 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 | 3.98996 |
| ARHGEF39 | Rho guanine nucleotide exchange factor (GEF) 39 | 3.96552 |
| ACOT2 | acyl-CoA thioesterase 2 | 3.9122 |
| TP53I13 | tumor protein p53 inducible protein 13 | 3.90866 |
| JUND | jun D proto-oncogene | 3.90155 |
| FAM228B | family with sequence similarity 228, member B | 3.89363 |
| CNTD1 | cyclin N-terminal domain containing 1 | 3.82714 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 3.8053 |
| TSC2 | tuberous sclerosis 2 | 3.79382 |
| STRADB | STE20-related kinase adaptor beta | 3.79192 |
| RBM7 | RNA binding motif protein 7 | 3.78977 |
| AGBL5 | ATP/GTP binding protein-like 5 | 3.77227 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 3.74657 |
| LYPD1 | LY6/PLAUR domain containing 1 | 3.70016 |
| PXDC1 | PX domain containing 1 | 3.64859 |
| SRRM5 | serine/arginine repetitive matrix 5 | 3.63226 |
| CLVS1 | clavesin 1 | 3.61569 |
| TMEM198 | transmembrane protein 198 | 3.61536 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | 3.60797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DSE | dermatan sulfate epimerase | -20.0 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -20.0 |
| EXOSC9 | exosome component 9 | -20.0 |
| TRIM59 | tripartite motif containing 59 | -20.0 |
| HAS3 | hyaluronan synthase 3 | -20.0 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -20.0 |
| ACOT13 | acyl-CoA thioesterase 13 | -20.0 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | -20.0 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | -20.0 |
| GPR39 | G protein-coupled receptor 39 | -20.0 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -20.0 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 | -20.0 |
| ADCY3 | adenylate cyclase 3 | -20.0 |
| SULF2 | sulfatase 2 | -18.8861 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -17.3019 |
| KLC1 | kinesin light chain 1 | -16.8788 |
| B9D1 | B9 protein domain 1 | -16.4928 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | -16.3979 |
| PMEL | premelanosome protein | -16.1062 |
| SAMD11 | sterile alpha motif domain containing 11 | -14.6468 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) | -14.3427 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -13.4123 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -13.2934 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -13.2821 |
| FAM166A | family with sequence similarity 166, member A | -12.8927 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -12.8876 |
| INTS8 | integrator complex subunit 8 | -12.4741 |
| CCDC107 | coiled-coil domain containing 107 | -12.4559 |
| GLRX2 | glutaredoxin 2 | -12.414 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -11.6774 |
| IFT80 | intraflagellar transport 80 | -11.5854 |
| NT5DC4 | 5'-nucleotidase domain containing 4 | -11.3519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -11.2727 |
| LOC122455342 | testis-specific serine/proline-rich protein | -10.9831 |
| ZNF276 | zinc finger protein 276 | -10.628 |
| FANCD2OS | FANCD2 opposite strand | -10.3032 |
| LRRC59 | leucine rich repeat containing 59 | -10.0429 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -9.66886 |
| LCTL | lactase-like | -9.56069 |
| SLC51A | solute carrier family 51, alpha subunit | -9.10003 |
| PLLP | plasmolipin | -8.98795 |
| MLX | MLX, MAX dimerization protein | -8.77819 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like | -8.09752 |
| KIF7 | kinesin family member 7 | -7.98147 |
| FAM149B1 | family with sequence similarity 149, member B1 | -7.87121 |
| C9ORF43 | chromosome 9 open reading frame 43 | -7.83601 |
| KIAA0895 | KIAA0895 | -7.77096 |
| KIF1B | kinesin family member 1B | -7.75937 |
| PAQR4 | progestin and adipoQ receptor family member IV | -7.69113 |
| SAMD14 | sterile alpha motif domain containing 14 | -7.3274 |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 | -7.30132 |
| FEN1 | flap structure-specific endonuclease 1 | -7.20961 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | -7.19506 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -7.12142 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -7.04152 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -7.03773 |
| POLG | polymerase (DNA directed), gamma | -6.89223 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -6.26674 |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | -6.14148 |
| ZC3H14 | zinc finger CCCH-type containing 14 | -5.96849 |
| TEFM | transcription elongation factor, mitochondrial | -5.90338 |
| CPSF4L | cleavage and polyadenylation specific factor 4-like | -5.87411 |
| MYO19 | myosin XIX | -5.85217 |
| HSPA8 | heat shock 70kDa protein 8 | -5.63992 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -5.54625 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | -5.52541 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -5.42276 |
| C5ORF45 | chromosome 5 open reading frame 45 | -5.35401 |
| NECAB1 | N-terminal EF-hand calcium binding protein 1 | -5.33988 |
| NOSTRIN | nitric oxide synthase trafficking | -5.26017 |
| ENOSF1 | enolase superfamily member 1 | -5.06286 |
| DND1 | DND microRNA-mediated repression inhibitor 1 | -4.95923 |
| SLA2 | Src-like-adaptor 2 | -4.86891 |
| CLCC1 | chloride channel CLIC-like 1 | -4.85207 |
| DIS3L | DIS3 like exosome 3'-5' exoribonuclease | -4.77591 |
| RPS29 | ribosomal protein S29 | -4.76266 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -4.7483 |
| ANXA1 | annexin A1 | -4.63887 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -4.56041 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | -4.55975 |
| KPNB1 | karyopherin (importin) beta 1 | -4.52264 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -4.40619 |
| RRM2 | ribonucleotide reductase M2 | -4.33713 |
| HSPA4 | heat shock 70kDa protein 4 | -4.16022 |
| GYG1 | glycogenin 1 | -4.09712 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -4.08714 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) | -4.04687 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -4.03942 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -4.01967 |
| FAM122C | family with sequence similarity 122C | -4.0039 |
| NCL | nucleolin | -3.95512 |
| RPL4 | ribosomal protein L4 | -3.90114 |
| RIC3 | RIC3 acetylcholine receptor chaperone | -3.89985 |
| KIF20A | kinesin family member 20A | -3.88937 |
| DOC2A | double C2-like domains, alpha | -3.8304 |
| SLC35B4 | solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 | -3.82195 |
| EML5 | echinoderm microtubule associated protein like 5 | -3.77227 |
| DDIT3 | DNA-damage-inducible transcript 3 | -3.76606 |
| TMPO | thymopoietin | -3.70853 |
| MFSD6 | major facilitator superfamily domain containing 6 | -3.7041 |
