| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting BCL2L1 in embryonic stem cell H9 cell line (Study accession: SRP131666) (PerturbAtlas) |
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199 genes differentially expressed following the Perturb_4878_OE_BCL2L1_SRP131666 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 9.4859 |
| ARRB1 | arrestin, beta 1 | 6.89382 |
| ABHD12B | abhydrolase domain containing 12B | 6.60576 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 6.44358 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 5.5704 |
| ZDHHC22 | zinc finger, DHHC-type containing 22 | 4.74019 |
| FAAH | fatty acid amide hydrolase | 4.16909 |
| SQLE | squalene epoxidase | 3.95243 |
| BBS9 | Bardet-Biedl syndrome 9 | 3.75095 |
| SCGB3A2 | secretoglobin, family 3A, member 2 | 3.59283 |
| SFRP1 | secreted frizzled-related protein 1 | 3.42617 |
| NCL | nucleolin | 3.39753 |
| AGO2 | argonaute RISC catalytic component 2 | 3.23306 |
| EPCAM | epithelial cell adhesion molecule | 3.12727 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 3.01228 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 3.01228 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 2.99471 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 2.95719 |
| CTBP2 | C-terminal binding protein 2 | 2.81043 |
| HIPK1 | homeodomain interacting protein kinase 1 | 2.80481 |
| FAM212B | family with sequence similarity 212, member B | 2.61782 |
| BTG2 | BTG family, member 2 | 2.61699 |
| PHACTR4 | phosphatase and actin regulator 4 | 2.59538 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | 2.50194 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 2.49259 |
| PEG10 | paternally expressed 10 | 2.49241 |
| FADS1 | fatty acid desaturase 1 | 2.41988 |
| RPL7 | ribosomal protein L7 | 2.4155 |
| EIF4B | eukaryotic translation initiation factor 4B | 2.40376 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 2.37437 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 2.34527 |
| PRDX4 | peroxiredoxin 4 | 2.31576 |
| DUSP6 | dual specificity phosphatase 6 | 2.30028 |
| GLDC | glycine dehydrogenase (decarboxylating) | 2.30028 |
| GPM6B | glycoprotein M6B | 2.29561 |
| CACYBP | calcyclin binding protein | 2.28145 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 2.25659 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 2.25633 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 2.22724 |
| CDV3 | CDV3 homolog (mouse) | 2.2102 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | 2.20221 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta | 2.17704 |
| SMS | spermine synthase | 2.17704 |
| CD24 | CD24 molecule | 2.09764 |
| RPL5 | ribosomal protein L5 | 2.07913 |
| C14ORF166 | chromosome 14 open reading frame 166 | 2.07537 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 2.03703 |
| SEPHS1 | selenophosphate synthetase 1 | 2.02539 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 1.97722 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 1.8742 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) | 1.85695 |
| TMSB4X | thymosin beta 4, X-linked | 1.83029 |
| SET | SET nuclear proto-oncogene | 1.82435 |
| AGO1 | argonaute RISC catalytic component 1 | 1.82435 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 1.81255 |
| ANKRD10 | ankyrin repeat domain 10 | 1.76948 |
| HHLA1 | HERV-H LTR-associating 1 | 1.76948 |
| ATCAY | ataxia, cerebellar, Cayman type | 1.76635 |
| METTL5 | methyltransferase like 5 | 1.75732 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 1.73449 |
| AK4 | adenylate kinase 4 | 1.70267 |
| BRD3 | bromodomain containing 3 | 1.70046 |
| EMC4 | ER membrane protein complex subunit 4 | 1.69863 |
| LINC00371 | long intergenic non-protein coding RNA 371 | 1.69863 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 1.68933 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 1.68933 |
| PTMA | prothymosin, alpha | 1.68781 |
| NEK9 | NIMA-related kinase 9 | 1.67558 |
| NAV1 | neuron navigator 1 | 1.58839 |
| CHGA | chromogranin A | 1.58176 |
| ARHGAP35 | Rho GTPase activating protein 35 | 1.57725 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 1.56 |
| CMIP | c-Maf inducing protein | 1.55578 |
| DPYSL3 | dihydropyrimidinase-like 3 | 1.55481 |
| EPT1 | ethanolaminephosphotransferase 1 | 1.52498 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 1.50079 |
| ZNF282 | zinc finger protein 282 | 1.49172 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 | 1.45996 |
| KAT7 | K(lysine) acetyltransferase 7 | 1.45669 |
| NUDCD2 | NudC domain containing 2 | 1.43114 |
| LITAF | lipopolysaccharide-induced TNF factor | 1.42607 |
| NOTCH1 | notch 1 | 1.42607 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 1.40619 |
| SSBP3 | single stranded DNA binding protein 3 | 1.39121 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 1.39121 |
| MCM4 | minichromosome maintenance complex component 4 | 1.39121 |
| HSPA8 | heat shock 70kDa protein 8 | 1.36117 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 1.36117 |
| TFRC | transferrin receptor | 1.3529 |
| IVNS1ABP | influenza virus NS1A binding protein | 1.34714 |
| TMEM97 | transmembrane protein 97 | 1.34714 |
| KARS | lysyl-tRNA synthetase | 1.34714 |
| PPA1 | pyrophosphatase (inorganic) 1 | 1.34714 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 1.34714 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 1.34714 |
| ATP11A | ATPase, class VI, type 11A | 1.34711 |
| DPYSL2 | dihydropyrimidinase-like 2 | 1.3408 |
| DRG1 | developmentally regulated GTP binding protein 1 | 1.33348 |
| HIP1 | huntingtin interacting protein 1 | 1.3179 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -12.5481 |
| TAGLN | transgelin | -11.7997 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | -8.08814 |
| TRIB3 | tribbles pseudokinase 3 | -7.69396 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -7.44298 |
| DUSP23 | dual specificity phosphatase 23 | -7.0656 |
| HGH1 | HGH1 homolog (S. cerevisiae) | -6.60576 |
| MYL9 | myosin, light chain 9, regulatory | -5.86258 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -5.5704 |
| LDHA | lactate dehydrogenase A | -5.27453 |
| RBM14 | RNA binding motif protein 14 | -5.16219 |
| AJUBA | ajuba LIM protein | -5.12223 |
| REPIN1 | replication initiator 1 | -4.99697 |
| VWA1 | von Willebrand factor A domain containing 1 | -4.7789 |
| RPL39L | ribosomal protein L39-like | -4.40842 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -4.00091 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 | -3.98513 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -3.89988 |
| CLSTN1 | calsyntenin 1 | -3.77051 |
| PCBP3 | poly(rC) binding protein 3 | -3.60983 |
| INHBE | inhibin, beta E | -3.60983 |
| CMTM3 | CKLF-like MARVEL transmembrane domain containing 3 | -3.59283 |
| BOK | BCL2-related ovarian killer | -3.30357 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -3.24722 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | -2.95047 |
| SLC38A10 | solute carrier family 38, member 10 | -2.88531 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.87635 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | -2.84008 |
| AARS | alanyl-tRNA synthetase | -2.78116 |
| RAB17 | RAB17, member RAS oncogene family | -2.78116 |
| NLRX1 | NLR family member X1 | -2.68543 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -2.62982 |
| AKNA | AT-hook transcription factor | -2.61782 |
| SCAMP4 | secretory carrier membrane protein 4 | -2.59133 |
| MAT2A | methionine adenosyltransferase II, alpha | -2.59133 |
| GSTM1 | glutathione S-transferase mu 1 | -2.58293 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.58293 |
| SLC35A4 | solute carrier family 35, member A4 | -2.52227 |
| TNKS1BP1 | tankyrase 1 binding protein 1, 182kDa | -2.50928 |
| COL26A1 | collagen, type XXVI, alpha 1 | -2.50194 |
| ULK3 | unc-51 like kinase 3 | -2.47131 |
| BCAS3 | breast carcinoma amplified sequence 3 | -2.41988 |
| GMFB | glia maturation factor, beta | -2.40376 |
| SLC35B2 | solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 | -2.35635 |
| WDR13 | WD repeat domain 13 | -2.30028 |
| LEMD2 | LEM domain containing 2 | -2.25659 |
| NMD3 | NMD3 ribosome export adaptor | -2.2102 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -2.2102 |
| MAP7D1 | MAP7 domain containing 1 | -2.19813 |
| WDR54 | WD repeat domain 54 | -2.16773 |
| KHNYN | KH and NYN domain containing | -2.15854 |
| CCNA2 | cyclin A2 | -2.12608 |
| CAPN5 | calpain 5 | -2.12378 |
| LRRC40 | leucine rich repeat containing 40 | -2.08459 |
| MED16 | mediator complex subunit 16 | -2.04252 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -2.04252 |
| THEM6 | thioesterase superfamily member 6 | -2.03293 |
| SESN2 | sestrin 2 | -2.03293 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 | -2.02514 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -1.99534 |
| SEMA6C | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | -1.98812 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | -1.96853 |
| MEN1 | multiple endocrine neoplasia I | -1.96641 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -1.96641 |
| ENO2 | enolase 2 (gamma, neuronal) | -1.96166 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -1.96166 |
| C8ORF82 | chromosome 8 open reading frame 82 | -1.88328 |
| PTDSS2 | phosphatidylserine synthase 2 | -1.88328 |
| FLOT2 | flotillin 2 | -1.87838 |
| PUS1 | pseudouridylate synthase 1 | -1.8742 |
| PODXL2 | podocalyxin-like 2 | -1.84211 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | -1.84188 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -1.82435 |
| INTS5 | integrator complex subunit 5 | -1.81255 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | -1.78193 |
| TMEM222 | transmembrane protein 222 | -1.78046 |
| PCDH1 | protocadherin 1 | -1.77957 |
| PTOV1 | prostate tumor overexpressed 1 | -1.76948 |
| BCKDK | branched chain ketoacid dehydrogenase kinase | -1.76948 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | -1.76948 |
| CCNG1 | cyclin G1 | -1.71414 |
| EXOC7 | exocyst complex component 7 | -1.70046 |
| CBX2 | chromobox homolog 2 | -1.70046 |
| CECR5 | cat eye syndrome chromosome region, candidate 5 | -1.69383 |
| PLD2 | phospholipase D2 | -1.68933 |
| TBC1D13 | TBC1 domain family, member 13 | -1.68933 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) | -1.68933 |
| TMTC3 | transmembrane and tetratricopeptide repeat containing 3 | -1.68933 |
| H2AFX | H2A histone family, member X | -1.68602 |
| MAST2 | microtubule associated serine/threonine kinase 2 | -1.68602 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -1.64959 |
| ADAM10 | ADAM metallopeptidase domain 10 | -1.64103 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -1.63417 |
| NISCH | nischarin | -1.62454 |
| ESYT1 | extended synaptotagmin-like protein 1 | -1.62413 |
| TSC22D3 | TSC22 domain family, member 3 | -1.62413 |
| TEF | thyrotrophic embryonic factor | -1.62413 |
| FAM160A2 | family with sequence similarity 160, member A2 | -1.58176 |
| CROCC | ciliary rootlet coiled-coil, rootletin | -1.57725 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -1.57225 |
