| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting TP53 in embryonic stem cell H9 cell line (Study accession: SRP131666) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_4881_KD_TP53_SRP131666 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAT2A | methionine adenosyltransferase II, alpha | 20.0 |
| INHBE | inhibin, beta E | 11.1862 |
| TPT1 | tumor protein, translationally-controlled 1 | 11.0123 |
| MRPS12 | mitochondrial ribosomal protein S12 | 10.6182 |
| RPL17 | ribosomal protein L17 | 10.557 |
| RPL34 | ribosomal protein L34 | 9.929 |
| RPL35A | ribosomal protein L35a | 9.86299 |
| RPS27A | ribosomal protein S27a | 9.60032 |
| RPS24 | ribosomal protein S24 | 9.50981 |
| PSAT1 | phosphoserine aminotransferase 1 | 9.36508 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | 9.21138 |
| RPL24 | ribosomal protein L24 | 9.17786 |
| RPS29 | ribosomal protein S29 | 9.08318 |
| RPL5 | ribosomal protein L5 | 9.0678 |
| NPTN | neuroplastin | 8.90248 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 8.88912 |
| RPS21 | ribosomal protein S21 | 8.71517 |
| RPL37 | ribosomal protein L37 | 8.68197 |
| RPL31 | ribosomal protein L31 | 8.60869 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 8.56117 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 8.4014 |
| RPL32 | ribosomal protein L32 | 8.34538 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 8.30535 |
| TMSB4X | thymosin beta 4, X-linked | 8.14214 |
| SLIRP | SRA stem-loop interacting RNA binding protein | 8.1052 |
| RPL22L1 | ribosomal protein L22-like 1 | 8.08807 |
| RPS7 | ribosomal protein S7 | 8.01325 |
| WARS | tryptophanyl-tRNA synthetase | 8.00793 |
| BFAR | bifunctional apoptosis regulator | 7.98668 |
| ANXA7 | annexin A7 | 7.9389 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 7.90277 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 7.74316 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 7.61093 |
| SARS | seryl-tRNA synthetase | 7.54283 |
| RPL38 | ribosomal protein L38 | 7.50733 |
| ATF4 | activating transcription factor 4 | 7.48598 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 7.48398 |
| ATP5E | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | 7.4438 |
| BEX1 | brain expressed, X-linked 1 | 7.43047 |
| RPL11 | ribosomal protein L11 | 7.42395 |
| RPL30 | ribosomal protein L30 | 7.35127 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 7.20798 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 7.2076 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 7.19875 |
| LSG1 | large 60S subunit nuclear export GTPase 1 | 7.19336 |
| NOP10 | NOP10 ribonucleoprotein | 7.18209 |
| RPL14 | ribosomal protein L14 | 7.17608 |
| RPS25 | ribosomal protein S25 | 7.11914 |
| RPL28 | ribosomal protein L28 | 7.07829 |
| MRPS28 | mitochondrial ribosomal protein S28 | 7.06884 |
| RPL12 | ribosomal protein L12 | 7.06639 |
| RPS3A | ribosomal protein S3A | 6.98101 |
| DNAJC19 | DnaJ (Hsp40) homolog, subfamily C, member 19 | 6.95996 |
| RPL27 | ribosomal protein L27 | 6.92475 |
| RPL37A | ribosomal protein L37a | 6.89926 |
| RPS20 | ribosomal protein S20 | 6.88217 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 6.86851 |
| RPL39 | ribosomal protein L39 | 6.85738 |
| RGS16 | regulator of G-protein signaling 16 | 6.85677 |
| OAT | ornithine aminotransferase | 6.83592 |
| TTC5 | tetratricopeptide repeat domain 5 | 6.7744 |
| RPS23 | ribosomal protein S23 | 6.71911 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | 6.70793 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 6.66258 |
| PLIN2 | perilipin 2 | 6.65065 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 6.5732 |
| RPL19 | ribosomal protein L19 | 6.5595 |
| SNX12 | sorting nexin 12 | 6.55781 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 6.54901 |
| RPS4X | ribosomal protein S4, X-linked | 6.52504 |
| USMG5 | up-regulated during skeletal muscle growth 5 homolog (mouse) | 6.50193 |
| RHOH | ras homolog family member H | 6.48852 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 6.47709 |
| PRSS8 | protease, serine, 8 | 6.47701 |
| S100A11 | S100 calcium binding protein A11 | 6.4649 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 6.43578 |
| EIF1B | eukaryotic translation initiation factor 1B | 6.43453 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 6.38733 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | 6.38457 |
| RPL6 | ribosomal protein L6 | 6.34987 |
| COX7C | cytochrome c oxidase subunit VIIc | 6.34851 |
| CTSC | cathepsin C | 6.34369 |
| RPL4 | ribosomal protein L4 | 6.34354 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 6.30381 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 6.29237 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 6.21072 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 6.20707 |
| ARRB1 | arrestin, beta 1 | 6.20135 |
| CDC42 | cell division cycle 42 | 6.19852 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 6.19751 |
| OTX2 | orthodenticle homeobox 2 | 6.17986 |
| PNP | purine nucleoside phosphorylase | 6.17155 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 6.14342 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 6.14146 |
| RPL7 | ribosomal protein L7 | 6.12506 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 6.10269 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E | 6.08663 |
| TIMMDC1 | translocase of inner mitochondrial membrane domain containing 1 | 6.07421 |
| RPS13 | ribosomal protein S13 | 6.07397 |
| CTH | cystathionine gamma-lyase | 6.0603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMG20B | high mobility group 20B | -20.0 |
| CORO1B | coronin, actin binding protein, 1B | -20.0 |
| MED16 | mediator complex subunit 16 | -20.0 |
| CTGF | connective tissue growth factor | -20.0 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -20.0 |
| MAP7D1 | MAP7 domain containing 1 | -20.0 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | -20.0 |
| HES6 | hes family bHLH transcription factor 6 | -20.0 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -20.0 |
| MRPL41 | mitochondrial ribosomal protein L41 | -20.0 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | -20.0 |
| CCDC85B | coiled-coil domain containing 85B | -20.0 |
| COL26A1 | collagen, type XXVI, alpha 1 | -20.0 |
| ALDH16A1 | aldehyde dehydrogenase 16 family, member A1 | -20.0 |
| TMC6 | transmembrane channel-like 6 | -20.0 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | -20.0 |
| MID1IP1 | MID1 interacting protein 1 | -20.0 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) | -20.0 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -20.0 |
| LIMD2 | LIM domain containing 2 | -20.0 |
| TMEM129 | transmembrane protein 129, E3 ubiquitin protein ligase | -20.0 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) | -20.0 |
| MTA1 | metastasis associated 1 | -20.0 |
| FBXW5 | F-box and WD repeat domain containing 5 | -20.0 |
| MPST | mercaptopyruvate sulfurtransferase | -20.0 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -20.0 |
| RBM42 | RNA binding motif protein 42 | -20.0 |
| NDN | necdin, melanoma antigen (MAGE) family member | -20.0 |
| C16ORF13 | chromosome 16 open reading frame 13 | -20.0 |
| UNC119 | unc-119 homolog (C. elegans) | -20.0 |
| MFSD3 | major facilitator superfamily domain containing 3 | -20.0 |
| TRABD | TraB domain containing | -20.0 |
| VASP | vasodilator-stimulated phosphoprotein | -20.0 |
| TONSL | tonsoku-like, DNA repair protein | -20.0 |
| BRAT1 | BRCA1-associated ATM activator 1 | -20.0 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -20.0 |
| C7ORF50 | chromosome 7 open reading frame 50 | -20.0 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -20.0 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | -20.0 |
| COL4A2 | collagen, type IV, alpha 2 | -20.0 |
| BOP1 | block of proliferation 1 | -20.0 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | -20.0 |
| WDR34 | WD repeat domain 34 | -20.0 |
| FPGS | folylpolyglutamate synthase | -20.0 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -20.0 |
| ANXA11 | annexin A11 | -20.0 |
| HAPLN3 | hyaluronan and proteoglycan link protein 3 | -20.0 |
| ZNF574 | zinc finger protein 574 | -20.0 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -20.0 |
| GRAMD1A | GRAM domain containing 1A | -20.0 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | -20.0 |
| DVL2 | dishevelled segment polarity protein 2 | -20.0 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -20.0 |
| DAPK3 | death-associated protein kinase 3 | -20.0 |
| ULK3 | unc-51 like kinase 3 | -20.0 |
| HDAC5 | histone deacetylase 5 | -20.0 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -20.0 |
| CERS4 | ceramide synthase 4 | -20.0 |
| PODXL2 | podocalyxin-like 2 | -20.0 |
| H2AFX | H2A histone family, member X | -20.0 |
| TRIP6 | thyroid hormone receptor interactor 6 | -20.0 |
| THOP1 | thimet oligopeptidase 1 | -20.0 |
| ZNF219 | zinc finger protein 219 | -20.0 |
| CCL13 | chemokine (C-C motif) ligand 13 | -20.0 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -20.0 |
| SORBS3 | sorbin and SH3 domain containing 3 | -20.0 |
| MAP1S | microtubule-associated protein 1S | -20.0 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase | -20.0 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -20.0 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -20.0 |
| TSEN54 | TSEN54 tRNA splicing endonuclease subunit | -20.0 |
| MFSD10 | major facilitator superfamily domain containing 10 | -20.0 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 | -20.0 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog | -20.0 |
| MRPS26 | mitochondrial ribosomal protein S26 | -20.0 |
| TTYH3 | tweety family member 3 | -20.0 |
| MED9 | mediator complex subunit 9 | -20.0 |
| C16ORF59 | chromosome 16 open reading frame 59 | -20.0 |
| R3HDM4 | R3H domain containing 4 | -20.0 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -20.0 |
| FAM189B | family with sequence similarity 189, member B | -20.0 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 | -20.0 |
| CENPV | centromere protein V | -20.0 |
| ATAD3A | ATPase family, AAA domain containing 3A | -20.0 |
| MDFI | MyoD family inhibitor | -20.0 |
| INTS1 | integrator complex subunit 1 | -20.0 |
| PRELID1 | PRELI domain containing 1 | -20.0 |
| SLC38A10 | solute carrier family 38, member 10 | -20.0 |
| FAM213B | family with sequence similarity 213, member B | -20.0 |
| ATP5D | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | -20.0 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -20.0 |
| KRT19 | keratin 19, type I | -20.0 |
| CYBA | cytochrome b-245, alpha polypeptide | -20.0 |
| HSF1 | heat shock transcription factor 1 | -20.0 |
| ZNF672 | zinc finger protein 672 | -20.0 |
| AGRN | agrin | -20.0 |
| TBCB | tubulin folding cofactor B | -20.0 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -20.0 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -20.0 |
| ATG4D | autophagy related 4D, cysteine peptidase | -20.0 |
