Perturb_4889_OE_BCL2L1_SRP131666 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting BCL2L1 in embryonic stem cell H9 cell line (Study accession: SRP131666) (PerturbAtlas)
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Genes

77 genes differentially expressed following the Perturb_4889_OE_BCL2L1_SRP131666 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
ARRB1 arrestin, beta 1 7.50312
ABHD12B abhydrolase domain containing 12B 7.09495
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 5.6976
ZDHHC22 zinc finger, DHHC-type containing 22 5.07668
SCGB3A2 secretoglobin, family 3A, member 2 4.61222
GNG4 guanine nucleotide binding protein (G protein), gamma 4 3.82125
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 2.9583
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 2.73473
HSPA8 heat shock 70kDa protein 8 2.50935
LECT1 leukocyte cell derived chemotaxin 1 2.35288
SRSF1 serine/arginine-rich splicing factor 1 2.28029
PRDX4 peroxiredoxin 4 2.23244
PDPN podoplanin 1.88632
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.69039
SLC38A5 solute carrier family 38, member 5 1.6555
FAAH fatty acid amide hydrolase 1.639
TCP1 t-complex 1 1.58156
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.57948
CHKB choline kinase beta 1.45998
PDZD4 PDZ domain containing 4 1.42552
ASS1 argininosuccinate synthase 1 1.42132
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.4139
PQBP1 polyglutamine binding protein 1 1.39092
HHLA1 HERV-H LTR-associating 1 1.39092

decreased expression

Symbol Name Standardized Value
SLIT2 slit homolog 2 (Drosophila) -8.72393
CCNA2 cyclin A2 -7.46182
TOP2A topoisomerase (DNA) II alpha 170kDa -6.6667
AASS aminoadipate-semialdehyde synthase -6.65127
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -5.69898
CTGF connective tissue growth factor -5.6976
GMFB glia maturation factor, beta -4.43927
CLTC clathrin, heavy chain (Hc) -4.22982
MYH10 myosin, heavy chain 10, non-muscle -4.14553
TAGLN transgelin -3.1315
RAB17 RAB17, member RAS oncogene family -2.95979
PCBP3 poly(rC) binding protein 3 -2.9583
ZNF146 zinc finger protein 146 -2.67117
LDHA lactate dehydrogenase A -2.52907
DUSP23 dual specificity phosphatase 23 -2.47956
COL9A3 collagen, type IX, alpha 3 -2.41437
CKAP5 cytoskeleton associated protein 5 -2.33936
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.31794
AHCTF1 AT hook containing transcription factor 1 -2.28029
H1F0 H1 histone family, member 0 -2.28029
NMD3 NMD3 ribosome export adaptor -2.28029
MAPK6 mitogen-activated protein kinase 6 -2.27998
DST dystonin -2.26148
APLN apelin -2.23244
IQGAP1 IQ motif containing GTPase activating protein 1 -2.21988
CAPN5 calpain 5 -2.13696
AJUBA ajuba LIM protein -2.13269
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.11237
ERVH48-1 endogenous retrovirus group 48, member 1 -2.07921
SCAMP1 secretory carrier membrane protein 1 -2.07921
SCFD1 sec1 family domain containing 1 -2.07921
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -1.97335
NGFR nerve growth factor receptor -1.90067
SPTBN1 spectrin, beta, non-erythrocytic 1 -1.89011
SOCS1 suppressor of cytokine signaling 1 -1.89011
USP9X ubiquitin specific peptidase 9, X-linked -1.89011
SF3B1 splicing factor 3b, subunit 1, 155kDa -1.87033
CCND2 cyclin D2 -1.81943
ADAM10 ADAM metallopeptidase domain 10 -1.74598
ZNF185 zinc finger protein 185 (LIM domain) -1.66899
THOC2 THO complex 2 -1.64281
SPTAN1 spectrin, alpha, non-erythrocytic 1 -1.57948
AP1M2 adaptor-related protein complex 1, mu 2 subunit -1.53154
CANT1 calcium activated nucleotidase 1 -1.47959
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -1.42827
CENPF centromere protein F, 350/400kDa -1.39849
ATRX alpha thalassemia/mental retardation syndrome X-linked -1.39537
CCNG1 cyclin G1 -1.39092
NUP160 nucleoporin 160kDa -1.39092
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.32706
ARCN1 archain 1 -1.31948
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -1.31589
MON2 MON2 homolog (S. cerevisiae) -1.30259