| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ARID1A in endometriotic epithelial cells 12Z-ESR1 cell line (Study accession: SRP356912) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_5426_KD_ARID1A_SRP356912 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 20.0 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 20.0 |
| SRFBP1 | serum response factor binding protein 1 | 20.0 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 20.0 |
| FSIP1 | fibrous sheath interacting protein 1 | 20.0 |
| ORAOV1 | oral cancer overexpressed 1 | 20.0 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | 20.0 |
| LYPD1 | LY6/PLAUR domain containing 1 | 20.0 |
| COL6A1 | collagen, type VI, alpha 1 | 16.0761 |
| THBS1 | thrombospondin 1 | 16.0551 |
| VIM | vimentin | 13.9843 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 12.9183 |
| PRNP | prion protein | 9.7192 |
| CTSL | cathepsin L | 9.17585 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | 8.92513 |
| ATG7 | autophagy related 7 | 8.83491 |
| PKD2L2 | polycystic kidney disease 2-like 2 | 8.79777 |
| CTGF | connective tissue growth factor | 8.41741 |
| RRBP1 | ribosome binding protein 1 | 8.30574 |
| COL6A2 | collagen, type VI, alpha 2 | 8.01036 |
| COL1A2 | collagen, type I, alpha 2 | 7.27634 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 7.2477 |
| ENO3 | enolase 3 (beta, muscle) | 7.03353 |
| CAST | calpastatin | 6.84858 |
| PEX14 | peroxisomal biogenesis factor 14 | 6.59437 |
| FAM166A | family with sequence similarity 166, member A | 6.39965 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | 6.21226 |
| CCNA1 | cyclin A1 | 5.87453 |
| PDAP1 | PDGFA associated protein 1 | 5.68789 |
| PLD4 | phospholipase D family, member 4 | 5.2144 |
| FLNB | filamin B, beta | 4.95912 |
| TRRAP | transformation/transcription domain-associated protein | 4.93478 |
| MYO10 | myosin X | 4.92004 |
| MEN1 | multiple endocrine neoplasia I | 4.69753 |
| SRR | serine racemase | 4.60671 |
| HEXB | hexosaminidase B (beta polypeptide) | 4.36207 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 4.20347 |
| RNF24 | ring finger protein 24 | 4.18714 |
| KRT17 | keratin 17, type I | 4.10282 |
| BTD | biotinidase | 4.09287 |
| RYR3 | ryanodine receptor 3 | 4.04127 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 4.03846 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 4.00655 |
| HIC1 | hypermethylated in cancer 1 | 3.7995 |
| EPHA2 | EPH receptor A2 | 3.72787 |
| FOSL1 | FOS-like antigen 1 | 3.7117 |
| GANC | glucosidase, alpha; neutral C | 3.68591 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 3.59333 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 3.50774 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | 3.41749 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 3.32723 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | 3.3043 |
| CCND1 | cyclin D1 | 3.30202 |
| CTSA | cathepsin A | 3.15865 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 3.09844 |
| ZNF814 | zinc finger protein 814 | 3.07815 |
| ZNF511 | zinc finger protein 511 | 3.03799 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 2.89122 |
| ERCC1 | excision repair cross-complementation group 1 | 2.83054 |
| MYL9 | myosin, light chain 9, regulatory | 2.76812 |
| TMSB4X | thymosin beta 4, X-linked | 2.74591 |
| CCNH | cyclin H | 2.67866 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 2.64732 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 2.64732 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 2.58862 |
| RAD17 | RAD17 homolog (S. pombe) | 2.49479 |
| SOX9 | SRY (sex determining region Y)-box 9 | 2.45655 |
| ENOSF1 | enolase superfamily member 1 | 2.43384 |
| C17ORF104 | chromosome 17 open reading frame 104 | 2.41302 |
| PFN1 | profilin 1 | 2.40053 |
| SNX32 | sorting nexin 32 | 2.39975 |
| CALR | calreticulin | 2.39529 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | 2.36475 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.3319 |
| LAMA5 | laminin, alpha 5 | 2.28712 |
| NUP153 | nucleoporin 153kDa | 2.27653 |
| CCDC85B | coiled-coil domain containing 85B | 2.26673 |
| COL4A2 | collagen, type IV, alpha 2 | 2.21574 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 2.20942 |
| ZNF575 | zinc finger protein 575 | 2.18704 |
| CCDC85C | coiled-coil domain containing 85C | 2.18036 |
| MROH8 | maestro heat-like repeat family member 8 | 2.17711 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 | 2.16949 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 2.14808 |
| FAM3C | family with sequence similarity 3, member C | 2.12411 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | 2.11142 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 2.11142 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.09325 |
| C19ORF44 | chromosome 19 open reading frame 44 | 2.08789 |
| IRS2 | insulin receptor substrate 2 | 2.07345 |
| NCL | nucleolin | 2.0064 |
| PRPF31 | pre-mRNA processing factor 31 | 2.00192 |
| ZNF227 | zinc finger protein 227 | 1.91498 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 1.90239 |
| DPP9 | dipeptidyl-peptidase 9 | 1.88119 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | 1.88119 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 1.87325 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 1.86757 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -20.0 |
| CASKIN1 | CASK interacting protein 1 | -20.0 |
| CCDC152 | coiled-coil domain containing 152 | -20.0 |
| FADS1 | fatty acid desaturase 1 | -20.0 |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase | -20.0 |
| C22ORF23 | chromosome 22 open reading frame 23 | -20.0 |
| HIST1H4I | histone cluster 1, H4i | -20.0 |
| SNX22 | sorting nexin 22 | -20.0 |
| MPI | mannose phosphate isomerase | -20.0 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | -20.0 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -20.0 |
| ZBTB46 | zinc finger and BTB domain containing 46 | -20.0 |
| GLIPR1 | GLI pathogenesis-related 1 | -17.4962 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | -16.9983 |
| TMEM258 | transmembrane protein 258 | -15.9656 |
| RAPSN | receptor-associated protein of the synapse | -15.6756 |
| TCP1 | t-complex 1 | -13.7015 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -12.8912 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -12.5688 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | -12.5688 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -12.2927 |
| SAMD14 | sterile alpha motif domain containing 14 | -12.2836 |
| PEX10 | peroxisomal biogenesis factor 10 | -11.6411 |
| SPC24 | SPC24, NDC80 kinetochore complex component | -11.1899 |
| C14ORF166 | chromosome 14 open reading frame 166 | -11.1033 |
| HARBI1 | harbinger transposase derived 1 | -11.0551 |
| EPB41 | erythrocyte membrane protein band 4.1 | -10.9618 |
| TMEM53 | transmembrane protein 53 | -10.8653 |
| PRPF39 | pre-mRNA processing factor 39 | -9.52053 |
| FZD4 | frizzled class receptor 4 | -8.93643 |
| BBIP1 | BBSome interacting protein 1 | -8.92513 |
| BEST1 | bestrophin 1 | -8.84836 |
| C1ORF54 | chromosome 1 open reading frame 54 | -8.27934 |
| NECAB1 | N-terminal EF-hand calcium binding protein 1 | -8.24503 |
| SLC2A4RG | SLC2A4 regulator | -8.20446 |
| CDK4 | cyclin-dependent kinase 4 | -8.0514 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -7.93109 |
| LRRC75A | leucine rich repeat containing 75A | -7.86709 |
| LOC122455342 | testis-specific serine/proline-rich protein | -7.77528 |
| MED12L | mediator complex subunit 12-like | -7.46794 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -7.20373 |
| E2F5 | E2F transcription factor 5, p130-binding | -6.93084 |
| CDC42SE1 | CDC42 small effector 1 | -6.6964 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor | -6.69327 |
| UNC45A | unc-45 homolog A (C. elegans) | -6.44529 |
| C11ORF57 | chromosome 11 open reading frame 57 | -6.44464 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -6.18195 |
| CFAP126 | cilia and flagella associated protein 126 | -6.01311 |
| C2ORF16 | chromosome 2 open reading frame 16 | -5.72254 |
| MAP7D1 | MAP7 domain containing 1 | -5.61972 |
| RBBP4 | retinoblastoma binding protein 4 | -5.61972 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -5.34273 |
| TMEM97 | transmembrane protein 97 | -5.3128 |
| SFRP1 | secreted frizzled-related protein 1 | -5.27764 |
| ALX3 | ALX homeobox 3 | -5.16494 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -5.16486 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -5.15902 |
| INTS8 | integrator complex subunit 8 | -5.09924 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -4.93652 |
| AXL | AXL receptor tyrosine kinase | -4.88731 |
| TMEM200B | transmembrane protein 200B | -4.80075 |
| H2AFY | H2A histone family, member Y | -4.59337 |
| SIK2 | salt-inducible kinase 2 | -4.47102 |
| FAM175A | family with sequence similarity 175, member A | -4.42589 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -4.37737 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -4.2515 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | -4.21168 |
| MVK | mevalonate kinase | -4.21056 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | -4.17264 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -4.15904 |
| RNF214 | ring finger protein 214 | -4.03889 |
| CPM | carboxypeptidase M | -4.02487 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -4.0037 |
| GCSAM | germinal center-associated, signaling and motility | -3.89726 |
| TNPO1 | transportin 1 | -3.83221 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | -3.82893 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -3.66488 |
| FTL | ferritin, light polypeptide | -3.57993 |
| NR2C2AP | nuclear receptor 2C2-associated protein | -3.56117 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -3.52965 |
| C5ORF45 | chromosome 5 open reading frame 45 | -3.51456 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -3.38401 |
| SATL1 | spermidine/spermine N1-acetyl transferase-like 1 | -3.37953 |
| SARM1 | sterile alpha and TIR motif containing 1 | -3.3394 |
| NOL7 | nucleolar protein 7, 27kDa | -3.24791 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -3.24765 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -3.2306 |
| CRLS1 | cardiolipin synthase 1 | -3.22688 |
| SMCR8 | Smith-Magenis syndrome chromosome region, candidate 8 | -3.18599 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -3.14607 |
| DDHD2 | DDHD domain containing 2 | -3.07324 |
| B3GAT2 | beta-1,3-glucuronyltransferase 2 | -3.01591 |
| H1F0 | H1 histone family, member 0 | -2.98399 |
| LMNTD2 | lamin tail domain containing 2 | -2.98014 |
| JUND | jun D proto-oncogene | -2.97284 |
| MARCH7 | membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase | -2.94789 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -2.93908 |
| ZNF263 | zinc finger protein 263 | -2.91992 |
| ZNF503 | zinc finger protein 503 | -2.90895 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -2.9063 |
