| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting H3C1 in fibroblast cell line (Study accession: SRP106792) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_5880_OE_H3C1_SRP106792 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| USP53 | ubiquitin specific peptidase 53 | 20.0 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 20.0 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 20.0 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 20.0 |
| RTN4 | reticulon 4 | 20.0 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 20.0 |
| PALM2-AKAP2 | PALM2-AKAP2 readthrough | 20.0 |
| CD276 | CD276 molecule | 20.0 |
| EPAS1 | endothelial PAS domain protein 1 | 20.0 |
| H1F0 | H1 histone family, member 0 | 20.0 |
| LMAN1 | lectin, mannose-binding, 1 | 20.0 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 20.0 |
| SCARB2 | scavenger receptor class B, member 2 | 20.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | 20.0 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 20.0 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 20.0 |
| SDCBP | syndecan binding protein (syntenin) | 20.0 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 20.0 |
| LITAF | lipopolysaccharide-induced TNF factor | 20.0 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 20.0 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 20.0 |
| MACF1 | microtubule-actin crosslinking factor 1 | 20.0 |
| TNC | tenascin C | 20.0 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 20.0 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 20.0 |
| RNF213 | ring finger protein 213 | 20.0 |
| TNPO1 | transportin 1 | 20.0 |
| CSF1 | colony stimulating factor 1 (macrophage) | 20.0 |
| TXNRD1 | thioredoxin reductase 1 | 20.0 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 20.0 |
| CCND1 | cyclin D1 | 20.0 |
| LAMA4 | laminin, alpha 4 | 20.0 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 20.0 |
| MCFD2 | multiple coagulation factor deficiency 2 | 20.0 |
| ZC3H7B | zinc finger CCCH-type containing 7B | 20.0 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 20.0 |
| RAI14 | retinoic acid induced 14 | 20.0 |
| TMEM30A | transmembrane protein 30A | 20.0 |
| C3 | complement component 3 | 20.0 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 20.0 |
| COL4A1 | collagen, type IV, alpha 1 | 20.0 |
| FRMD6 | FERM domain containing 6 | 20.0 |
| TRIO | trio Rho guanine nucleotide exchange factor | 20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 20.0 |
| CD44 | CD44 molecule (Indian blood group) | 20.0 |
| CAPRIN1 | cell cycle associated protein 1 | 20.0 |
| CLSTN1 | calsyntenin 1 | 20.0 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 20.0 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 20.0 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 20.0 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 20.0 |
| MTPN | myotrophin | 20.0 |
| DST | dystonin | 20.0 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 20.0 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 20.0 |
| SCRN1 | secernin 1 | 20.0 |
| ADAM9 | ADAM metallopeptidase domain 9 | 20.0 |
| HEG1 | heart development protein with EGF-like domains 1 | 20.0 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 20.0 |
| B2M | beta-2-microglobulin | 20.0 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 20.0 |
| ANTXR1 | anthrax toxin receptor 1 | 20.0 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 20.0 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 20.0 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 20.0 |
| MCL1 | myeloid cell leukemia 1 | 20.0 |
| TRNP1 | TMF1-regulated nuclear protein 1 | 20.0 |
| HLA-B | major histocompatibility complex, class I, B | 20.0 |
| SLC38A1 | solute carrier family 38, member 1 | 20.0 |
| SLC38A2 | solute carrier family 38, member 2 | 20.0 |
| FBN1 | fibrillin 1 | 20.0 |
| CTSK | cathepsin K | 20.0 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 20.0 |
| ARHGAP29 | Rho GTPase activating protein 29 | 20.0 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 20.0 |
| LOXL4 | lysyl oxidase-like 4 | 20.0 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 20.0 |
| FGF2 | fibroblast growth factor 2 (basic) | 20.0 |
| MYLK | myosin light chain kinase | 20.0 |
| MLF2 | myeloid leukemia factor 2 | 20.0 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 20.0 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 20.0 |
| IL6ST | interleukin 6 signal transducer | 20.0 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 20.0 |
| GPNMB | glycoprotein (transmembrane) nmb | 20.0 |
| HLA-C | major histocompatibility complex, class I, C | 20.0 |
| PRRX1 | paired related homeobox 1 | 20.0 |
| TMEM132A | transmembrane protein 132A | 20.0 |
| SULF1 | sulfatase 1 | 20.0 |
| RND3 | Rho family GTPase 3 | 20.0 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 20.0 |
| NEK7 | NIMA-related kinase 7 | 20.0 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 20.0 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 20.0 |
| PRNP | prion protein | 20.0 |
| CANX | calnexin | 20.0 |
| MME | membrane metallo-endopeptidase | 20.0 |
| C1S | complement component 1, s subcomponent | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -20.0 |
| BMF | Bcl2 modifying factor | -20.0 |
| SEPT4 | septin 4 | -20.0 |
| SOX6 | SRY (sex determining region Y)-box 6 | -20.0 |
| INHBE | inhibin, beta E | -20.0 |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | -20.0 |
| LTC4S | leukotriene C4 synthase | -20.0 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -20.0 |
| LOC388849 | uncharacterized LOC388849 | -20.0 |
| TMEM91 | transmembrane protein 91 | -20.0 |
| IRF6 | interferon regulatory factor 6 | -20.0 |
| TBX15 | T-box 15 | -20.0 |
| P4HA3 | prolyl 4-hydroxylase, alpha polypeptide III | -20.0 |
| CCL8 | chemokine (C-C motif) ligand 8 | -20.0 |
| SHF | Src homology 2 domain containing F | -20.0 |
| GLIS1 | GLIS family zinc finger 1 | -20.0 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 | -20.0 |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -20.0 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -20.0 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit | -20.0 |
| FABP3 | fatty acid binding protein 3, muscle and heart | -20.0 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | -20.0 |
| NUDT8 | nudix (nucleoside diphosphate linked moiety X)-type motif 8 | -20.0 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | -20.0 |
| CHRD | chordin | -20.0 |
| FAM78A | family with sequence similarity 78, member A | -20.0 |
| LRRC71 | leucine rich repeat containing 71 | -20.0 |
| PNPLA3 | patatin-like phospholipase domain containing 3 | -20.0 |
| CBS | cystathionine-beta-synthase | -20.0 |
| KIAA0226L | KIAA0226-like | -20.0 |
| ASB5 | ankyrin repeat and SOCS box containing 5 | -20.0 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -20.0 |
| GIPR | gastric inhibitory polypeptide receptor | -20.0 |
| GBGT1 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 | -20.0 |
| HOXC11 | homeobox C11 | -20.0 |
| HOXC10 | homeobox C10 | -20.0 |
| SPAG4 | sperm associated antigen 4 | -20.0 |
| SAA1 | serum amyloid A1 | -20.0 |
| CPAMD8 | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 | -20.0 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -20.0 |
| ULBP1 | UL16 binding protein 1 | -20.0 |
| HOXC6 | homeobox C6 | -20.0 |
| AMPH | amphiphysin | -20.0 |
| TGFBR3L | transforming growth factor, beta receptor III-like | -20.0 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -20.0 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -20.0 |
| PRRT2 | proline-rich transmembrane protein 2 | -20.0 |
| PCBP3 | poly(rC) binding protein 3 | -20.0 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 | -20.0 |
| PTH1R | parathyroid hormone 1 receptor | -20.0 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | -20.0 |
| NTF3 | neurotrophin 3 | -20.0 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 | -20.0 |
| TMEM130 | transmembrane protein 130 | -20.0 |
| CBX8 | chromobox homolog 8 | -20.0 |
| HOXD9 | homeobox D9 | -20.0 |
| NAALADL1 | N-acetylated alpha-linked acidic dipeptidase-like 1 | -20.0 |
| PCED1B | PC-esterase domain containing 1B | -20.0 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -20.0 |
| VAX2 | ventral anterior homeobox 2 | -20.0 |
| DUSP23 | dual specificity phosphatase 23 | -20.0 |
| FAHD2B | fumarylacetoacetate hydrolase domain containing 2B | -20.0 |
| DOCK8 | dedicator of cytokinesis 8 | -20.0 |
| MYO15B | myosin XVB | -20.0 |
| CEND1 | cell cycle exit and neuronal differentiation 1 | -20.0 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | -20.0 |
| ABI3 | ABI family, member 3 | -20.0 |
| KIAA1683 | KIAA1683 | -20.0 |
| KRT33B | keratin 33B, type I | -20.0 |
| TRIM7 | tripartite motif containing 7 | -20.0 |
| SLC38A5 | solute carrier family 38, member 5 | -20.0 |
| HOXA9 | homeobox A9 | -20.0 |
| EMB | embigin | -20.0 |
| PEX11G | peroxisomal biogenesis factor 11 gamma | -20.0 |
| ACE | angiotensin I converting enzyme | -20.0 |
| CPM | carboxypeptidase M | -20.0 |
| GSTO2 | glutathione S-transferase omega 2 | -20.0 |
| IRX6 | iroquois homeobox 6 | -20.0 |
| IRX2 | iroquois homeobox 2 | -20.0 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -20.0 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -20.0 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -20.0 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -20.0 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | -20.0 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -20.0 |
| JCHAIN | joining chain of multimeric IgA and IgM | -20.0 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) | -20.0 |
| COMTD1 | catechol-O-methyltransferase domain containing 1 | -20.0 |
| RADIL | Ras association and DIL domains | -20.0 |
| KRT16 | keratin 16, type I | -20.0 |
| KRT15 | keratin 15, type I | -20.0 |
| HSPB3 | heat shock 27kDa protein 3 | -20.0 |
| FAM84A | family with sequence similarity 84, member A | -20.0 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -20.0 |
| ANKRD35 | ankyrin repeat domain 35 | -20.0 |
| RGN | regucalcin | -20.0 |
| PHYHD1 | phytanoyl-CoA dioxygenase domain containing 1 | -20.0 |
| MT1F | metallothionein 1F | -20.0 |
| KIF26A | kinesin family member 26A | -20.0 |
| CORO6 | coronin 6 | -20.0 |
