| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting RBM12B in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_5951_KD_RBM12B_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 20.0 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 14.986 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 11.6546 |
| SSFA2 | sperm specific antigen 2 | 11.6049 |
| RB1 | retinoblastoma 1 | 11.449 |
| FCHO2 | FCH domain only 2 | 10.9816 |
| CNST | consortin, connexin sorting protein | 10.6589 |
| ANLN | anillin, actin binding protein | 10.422 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 10.2632 |
| COL10A1 | collagen, type X, alpha 1 | 10.2632 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 10.2275 |
| ITGAV | integrin, alpha V | 10.1205 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 10.1205 |
| PHTF2 | putative homeodomain transcription factor 2 | 9.83963 |
| BTBD3 | BTB (POZ) domain containing 3 | 9.58918 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 9.51128 |
| KIAA1429 | KIAA1429 | 9.26954 |
| C7ORF60 | chromosome 7 open reading frame 60 | 9.05451 |
| KIAA1468 | KIAA1468 | 8.78945 |
| CLTC | clathrin, heavy chain (Hc) | 8.7085 |
| JAK2 | Janus kinase 2 | 8.70434 |
| LIN7C | lin-7 homolog C (C. elegans) | 8.28206 |
| FAR1 | fatty acyl CoA reductase 1 | 8.09199 |
| RNMT | RNA (guanine-7-) methyltransferase | 7.98487 |
| SEC24B | SEC24 family member B | 7.8413 |
| ATE1 | arginyltransferase 1 | 7.77269 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 7.75144 |
| MON2 | MON2 homolog (S. cerevisiae) | 7.65287 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 7.3196 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 7.30372 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 7.28646 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | 7.2261 |
| TTC21B | tetratricopeptide repeat domain 21B | 7.11852 |
| TTC37 | tetratricopeptide repeat domain 37 | 7.08056 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme | 7.08056 |
| TLR4 | toll-like receptor 4 | 6.90494 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 6.89435 |
| FEM1B | fem-1 homolog b (C. elegans) | 6.8841 |
| CGGBP1 | CGG triplet repeat binding protein 1 | 6.86913 |
| SCRN1 | secernin 1 | 6.80497 |
| CCND2 | cyclin D2 | 6.75766 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 6.73434 |
| FAM91A1 | family with sequence similarity 91, member A1 | 6.73033 |
| ARHGAP19 | Rho GTPase activating protein 19 | 6.70842 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 6.66341 |
| FGL2 | fibrinogen-like 2 | 6.65383 |
| NUP205 | nucleoporin 205kDa | 6.61123 |
| SMARCAD1 | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 | 6.53967 |
| ZBTB26 | zinc finger and BTB domain containing 26 | 6.53802 |
| CCL14 | chemokine (C-C motif) ligand 14 | 6.52716 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 6.40647 |
| IPO11 | importin 11 | 6.40647 |
| MED23 | mediator complex subunit 23 | 6.34705 |
| MLF2 | myeloid leukemia factor 2 | 6.29385 |
| IPO5 | importin 5 | 6.2817 |
| CLASP2 | cytoplasmic linker associated protein 2 | 6.2155 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 6.21424 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 6.13417 |
| ZNF525 | zinc finger protein 525 | 6.13417 |
| DOCK7 | dedicator of cytokinesis 7 | 6.12164 |
| KITLG | KIT ligand | 6.11224 |
| KIF11 | kinesin family member 11 | 6.01474 |
| ANKRD28 | ankyrin repeat domain 28 | 6.01121 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 6.00977 |
| PUM2 | pumilio RNA-binding family member 2 | 5.98339 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 5.97576 |
| ZBTB33 | zinc finger and BTB domain containing 33 | 5.96662 |
| HEATR5B | HEAT repeat containing 5B | 5.96662 |
| NUP160 | nucleoporin 160kDa | 5.84231 |
| MIER3 | mesoderm induction early response 1, family member 3 | 5.83048 |
| SUCO | SUN domain containing ossification factor | 5.78399 |
| NEGR1 | neuronal growth regulator 1 | 5.75947 |
| FAM160B1 | family with sequence similarity 160, member B1 | 5.73523 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 | 5.68275 |
| ATAD2 | ATPase family, AAA domain containing 2 | 5.61528 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 5.59241 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 5.56891 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 5.55769 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 5.55744 |
| FEM1C | fem-1 homolog c (C. elegans) | 5.49096 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 5.47425 |
| IDE | insulin-degrading enzyme | 5.47425 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | 5.47425 |
| CD2AP | CD2-associated protein | 5.45784 |
| STAG1 | stromal antigen 1 | 5.45548 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 5.45079 |
| MEF2A | myocyte enhancer factor 2A | 5.44163 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 5.44055 |
| ALCAM | activated leukocyte cell adhesion molecule | 5.36382 |
| LIN54 | lin-54 DREAM MuvB core complex component | 5.36382 |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 5.34928 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 5.33883 |
| ZMYM2 | zinc finger, MYM-type 2 | 5.33119 |
| STK38L | serine/threonine kinase 38 like | 5.32359 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 5.22012 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 5.15078 |
| TBC1D4 | TBC1 domain family, member 4 | 5.1291 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5.12141 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 5.10106 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit | 5.10106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -11.6546 |
| ALDOA | aldolase A, fructose-bisphosphate | -10.6589 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D | -10.155 |
| PRODH | proline dehydrogenase (oxidase) 1 | -9.83963 |
| HEPH | hephaestin | -9.72038 |
| SGK2 | serum/glucocorticoid regulated kinase 2 | -9.08257 |
| S100A3 | S100 calcium binding protein A3 | -8.78945 |
| CFB | complement factor B | -8.31167 |
| CLDN2 | claudin 2 | -8.06882 |
| DIO1 | deiodinase, iodothyronine, type I | -7.9417 |
| JUND | jun D proto-oncogene | -7.79366 |
| NNMT | nicotinamide N-methyltransferase | -7.70524 |
| GJB1 | gap junction protein, beta 1, 32kDa | -7.28002 |
| RNF186 | ring finger protein 186 | -7.20423 |
| METTL7B | methyltransferase like 7B | -7.19761 |
| IL32 | interleukin 32 | -6.71162 |
| TMEM37 | transmembrane protein 37 | -6.56193 |
| LMF1 | lipase maturation factor 1 | -6.53967 |
| LAD1 | ladinin 1 | -6.13686 |
| RAB24 | RAB24, member RAS oncogene family | -6.08725 |
| ABRACL | ABRA C-terminal like | -5.83055 |
| REEP6 | receptor accessory protein 6 | -5.80395 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -5.68275 |
| IL2RG | interleukin 2 receptor, gamma | -5.64378 |
| FOLR1 | folate receptor 1 (adult) | -5.55102 |
| DLK2 | delta-like 2 homolog (Drosophila) | -5.26729 |
| MUC21 | mucin 21, cell surface associated | -5.15078 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -5.10106 |
| TRAPPC8 | trafficking protein particle complex 8 | -4.90105 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -4.87192 |
| HPR | haptoglobin-related protein | -4.87192 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | -4.83325 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -4.80389 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -4.72756 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z | -4.72486 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | -4.72312 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -4.66377 |
| KRT18 | keratin 18, type I | -4.65867 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -4.6362 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -4.57884 |
| F11R | F11 receptor | -4.5724 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 | -4.41915 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | -4.37952 |
| EFHD1 | EF-hand domain family, member D1 | -4.37496 |
| ANKS4B | ankyrin repeat and sterile alpha motif domain containing 4B | -4.32297 |
| CES1 | carboxylesterase 1 | -4.31894 |
| TM4SF20 | transmembrane 4 L six family member 20 | -4.27967 |
| MUC12 | mucin 12, cell surface associated | -4.27809 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -4.24313 |
| CXCL16 | chemokine (C-X-C motif) ligand 16 | -4.21251 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -4.19861 |
| BST2 | bone marrow stromal cell antigen 2 | -4.17447 |
| AIF1L | allograft inflammatory factor 1-like | -4.06807 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -3.93442 |
| PLA2G16 | phospholipase A2, group XVI | -3.88525 |
| APOL1 | apolipoprotein L, 1 | -3.88525 |
| EPS8L3 | EPS8-like 3 | -3.84227 |
| CTSB | cathepsin B | -3.73984 |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | -3.68302 |
| RRBP1 | ribosome binding protein 1 | -3.6624 |
| ACY1 | aminoacylase 1 | -3.65173 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -3.59437 |
| HMOX2 | heme oxygenase 2 | -3.57127 |
| SAA1 | serum amyloid A1 | -3.56195 |
| WIPF3 | WAS/WASL interacting protein family, member 3 | -3.51259 |
| S100A1 | S100 calcium binding protein A1 | -3.48343 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | -3.48343 |
| SERPINE3 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 | -3.47586 |
| PIP | prolactin-induced protein | -3.43201 |
| BDKRB1 | bradykinin receptor B1 | -3.39813 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -3.39053 |
| ANKRD11 | ankyrin repeat domain 11 | -3.39042 |
| SHOX2 | short stature homeobox 2 | -3.39002 |
| PLA2G12B | phospholipase A2, group XIIB | -3.30668 |
| KHK | ketohexokinase (fructokinase) | -3.24603 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -3.21334 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -3.17949 |
| MTTP | microsomal triglyceride transfer protein | -3.15034 |
| PTMS | parathymosin | -3.14486 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -3.12957 |
| PDZD3 | PDZ domain containing 3 | -3.10678 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -3.10678 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 | -3.08455 |
| KRT78 | keratin 78, type II | -3.0828 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -3.07114 |
| ART5 | ADP-ribosyltransferase 5 | -3.06266 |
| F10 | coagulation factor X | -3.05708 |
| C6ORF132 | chromosome 6 open reading frame 132 | -3.03955 |
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | -3.01904 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -3.00606 |
| CTSA | cathepsin A | -3.00606 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | -3.00132 |
| FABP1 | fatty acid binding protein 1, liver | -3.00132 |
| GPX4 | glutathione peroxidase 4 | -3.00132 |
| TAT | tyrosine aminotransferase | -2.98949 |
| UGT1A9 | UDP glucuronosyltransferase 1 family, polypeptide A9 | -2.97756 |
| CD99 | CD99 molecule | -2.97362 |
| FTH1 | ferritin, heavy polypeptide 1 | -2.95732 |
| PTGES | prostaglandin E synthase | -2.94877 |
| ARRB1 | arrestin, beta 1 | -2.94085 |
