Perturb_5955_KD_RBMX_SRP271175 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting RBMX in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_5955_KD_RBMX_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
GLYATL1 glycine-N-acyltransferase-like 1 20.0
CLIC5 chloride intracellular channel 5 20.0
DCX doublecortin 20.0
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 20.0
IGSF23 immunoglobulin superfamily, member 23 20.0
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 19.1549
CCDC146 coiled-coil domain containing 146 18.4815
A1CF APOBEC1 complementation factor 16.8748
ZNF701 zinc finger protein 701 15.4146
GSTA2 glutathione S-transferase alpha 2 15.3024
ACMSD aminocarboxymuconate semialdehyde decarboxylase 12.9561
NRG1 neuregulin 1 12.7721
FAM134B family with sequence similarity 134, member B 12.0269
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 11.891
CNKSR2 connector enhancer of kinase suppressor of Ras 2 11.891
ESAM endothelial cell adhesion molecule 11.4888
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 11.3148
PRAMEF2 PRAME family member 2 10.8498
DNASE1L3 deoxyribonuclease I-like 3 10.4374
ZNF846 zinc finger protein 846 10.3348
SPANXN3 SPANX family, member N3 10.1351
TESPA1 thymocyte expressed, positive selection associated 1 9.90487
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 9.90386
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 9.62573
FYB FYN binding protein 9.56582
MOB3B MOB kinase activator 3B 9.15118
BAAT bile acid CoA:amino acid N-acyltransferase 9.10307
ACE2 angiotensin I converting enzyme 2 8.75976
EYS eyes shut homolog (Drosophila) 8.71045
C10ORF67 chromosome 10 open reading frame 67 8.69646
IGFL3 IGF-like family member 3 8.26101
MUC13 mucin 13, cell surface associated 8.04437
MRO maestro 8.01114
TLR4 toll-like receptor 4 7.97811
DIO1 deiodinase, iodothyronine, type I 7.92553
ADAMDEC1 ADAM-like, decysin 1 7.80763
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 7.5935
CCK cholecystokinin 7.48059
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 7.32471
CD163 CD163 molecule 7.2065
BMP3 bone morphogenetic protein 3 7.10896
FAM3D family with sequence similarity 3, member D 6.98866
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 6.96434
NR1H4 nuclear receptor subfamily 1, group H, member 4 6.95711
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 6.91142
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 6.7872
ANGPTL5 angiopoietin-like 5 6.74281
DENND1A DENN/MADD domain containing 1A 6.73828
CCL20 chemokine (C-C motif) ligand 20 6.72802
PADI2 peptidyl arginine deiminase, type II 6.72802
FHL1 four and a half LIM domains 1 6.70907
PRODH proline dehydrogenase (oxidase) 1 6.62545
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 6.61533
VNN1 vanin 1 6.57893
SDF4 stromal cell derived factor 4 6.42422
APOB apolipoprotein B 6.32749
S100A9 S100 calcium binding protein A9 6.30547
WIPF3 WAS/WASL interacting protein family, member 3 6.30547
ADORA3 adenosine A3 receptor 6.29818
NLRC4 NLR family, CARD domain containing 4 6.17626
ZNF560 zinc finger protein 560 5.98665
GS1-259H13.2 transmembrane protein 225-like 5.92951
WBP2NL WBP2 N-terminal like 5.86977
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 5.86552
CLDN1 claudin 1 5.80536
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 5.78759
CCRL2 chemokine (C-C motif) receptor-like 2 5.69084
BCL2L15 BCL2-like 15 5.60003
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 5.58026
AKAP6 A kinase (PRKA) anchor protein 6 5.52614
C1ORF116 chromosome 1 open reading frame 116 5.43848
SUGCT succinyl-CoA:glutarate-CoA transferase 5.43848
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 5.42925
RGCC regulator of cell cycle 5.38595
PSG2 pregnancy specific beta-1-glycoprotein 2 5.37679
MMP7 matrix metallopeptidase 7 5.36591
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 5.33076
CXCL9 chemokine (C-X-C motif) ligand 9 5.30985
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 5.28081
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 5.24204
CGN cingulin 5.13609
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 5.13414
ADM adrenomedullin 5.09529
AP1M2 adaptor-related protein complex 1, mu 2 subunit 5.0901
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5.07636
TMCO2 transmembrane and coiled-coil domains 2 4.95434
ADGRV1 adhesion G protein-coupled receptor V1 4.93169
TMIGD1 transmembrane and immunoglobulin domain containing 1 4.90398
FDX1 ferredoxin 1 4.88723
XIRP1 xin actin binding repeat containing 1 4.86625
NTNG1 netrin G1 4.84679
ZNF226 zinc finger protein 226 4.79141
LY75 lymphocyte antigen 75 4.7705
PRSS3 protease, serine, 3 4.69182
PQLC2 PQ loop repeat containing 2 4.56709
AFP alpha-fetoprotein 4.56601
SORBS2 sorbin and SH3 domain containing 2 4.52948
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 4.51384
SPINT2 serine peptidase inhibitor, Kunitz type, 2 4.49451
USH1C Usher syndrome 1C (autosomal recessive, severe) 4.48604

decreased expression

Symbol Name Standardized Value
RRM2 ribonucleotide reductase M2 -20.0
RBMX RNA binding motif protein, X-linked -20.0
OXSR1 oxidative stress responsive 1 -20.0
LMF1 lipase maturation factor 1 -20.0
PLK4 polo-like kinase 4 -19.699
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -17.6925
MKI67 marker of proliferation Ki-67 -16.9622
HIST1H1D histone cluster 1, H1d -15.2271
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -14.671
UQCRC2 ubiquinol-cytochrome c reductase core protein II -12.8458
KIF15 kinesin family member 15 -12.7721
ATAD2 ATPase family, AAA domain containing 2 -12.3155
HIST1H1A histone cluster 1, H1a -12.3155
SGOL2 shugoshin-like 2 (S. pombe) -12.2404
SHCBP1 SHC SH2-domain binding protein 1 -12.0269
EXO1 exonuclease 1 -11.4612
NCAPG non-SMC condensin I complex, subunit G -11.1155
TOP2A topoisomerase (DNA) II alpha 170kDa -10.9034
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -10.8519
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -10.8109
RBMXL1 RNA binding motif protein, X-linked-like 1 -10.7168
BARD1 BRCA1 associated RING domain 1 -10.1339
CCNA2 cyclin A2 -10.0833
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -10.0153
SKA1 spindle and kinetochore associated complex subunit 1 -9.72345
CKAP2L cytoskeleton associated protein 2-like -9.64629
PARP14 poly (ADP-ribose) polymerase family, member 14 -9.37644
WDR76 WD repeat domain 76 -9.16749
KIF4A kinesin family member 4A -8.96955
HJURP Holliday junction recognition protein -8.94347
SLFN11 schlafen family member 11 -8.71059
UHRF1 ubiquitin-like with PHD and ring finger domains 1 -8.69646
FANCD2 Fanconi anemia, complementation group D2 -8.68967
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -8.57735
KIF11 kinesin family member 11 -8.54962
LMNB1 lamin B1 -8.53194
HMGB2 high mobility group box 2 -8.44342
HELLS helicase, lymphoid-specific -8.35203
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -8.31064
RRM1 ribonucleotide reductase M1 -8.31064
MCM7 minichromosome maintenance complex component 7 -8.31064
MSH2 mutS homolog 2 -8.29175
TXNL4A thioredoxin-like 4A -8.29142
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -8.28476
TROAP trophinin associated protein -8.28405
DEPDC1 DEP domain containing 1 -8.0672
HIST1H1B histone cluster 1, H1b -8.05208
HIST1H4I histone cluster 1, H4i -8.01012
GCC1 GRIP and coiled-coil domain containing 1 -7.86931
NUF2 NUF2, NDC80 kinetochore complex component -7.85005
CDC6 cell division cycle 6 -7.85005
FAM151B family with sequence similarity 151, member B -7.79157
SLIT2 slit homolog 2 (Drosophila) -7.75989
DEPDC1B DEP domain containing 1B -7.74968
GTSE1 G-2 and S-phase expressed 1 -7.6345
KIAA0101 KIAA0101 -7.63389
FAM46A family with sequence similarity 46, member A -7.5749
CDK1 cyclin-dependent kinase 1 -7.56686
ORC1 origin recognition complex, subunit 1 -7.55664
TTC26 tetratricopeptide repeat domain 26 -7.42614
RFC5 replication factor C (activator 1) 5, 36.5kDa -7.37718
FOPNL FGFR1OP N-terminal like -7.3712
MCM5 minichromosome maintenance complex component 5 -7.28327
AASS aminoadipate-semialdehyde synthase -7.22719
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -7.2029
FBXO5 F-box protein 5 -7.16781
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -7.16579
ERCC6L excision repair cross-complementation group 6-like -7.11185
CENPO centromere protein O -7.10449
CCNE2 cyclin E2 -7.10296
CDCA7 cell division cycle associated 7 -6.98583
ANLN anillin, actin binding protein -6.87169
RRAGB Ras-related GTP binding B -6.87054
ATAD5 ATPase family, AAA domain containing 5 -6.81194
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -6.79636
NEIL3 nei endonuclease VIII-like 3 (E. coli) -6.73828
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -6.73806
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -6.70063
MTFMT mitochondrial methionyl-tRNA formyltransferase -6.65733
ZMPSTE24 zinc metallopeptidase STE24 -6.64287
KIF23 kinesin family member 23 -6.49181
CENPU centromere protein U -6.48988
WDHD1 WD repeat and HMG-box DNA binding protein 1 -6.48162
CLOCK clock circadian regulator -6.45838
FAM64A family with sequence similarity 64, member A -6.41561
GINS2 GINS complex subunit 2 (Psf2 homolog) -6.39605
PLK1 polo-like kinase 1 -6.26962
ARHGAP11A Rho GTPase activating protein 11A -6.26338
CEP295 centrosomal protein 295kDa -6.18691
ZC3H14 zinc finger CCCH-type containing 14 -6.09552
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 -6.08973
BIRC5 baculoviral IAP repeat containing 5 -6.0817
KIF2C kinesin family member 2C -6.07183
KIF20A kinesin family member 20A -6.04753
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -6.04753
TCF19 transcription factor 19 -6.04327
CDC45 cell division cycle 45 -6.03343
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -6.02986
KIAA1467 KIAA1467 -5.98643
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -5.90432