| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting TAF15 in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_5971_KD_TAF15_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ALS2CL | ALS2 C-terminal like | 13.2468 |
| RGAG1 | retrotransposon gag domain containing 1 | 12.4796 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 11.7484 |
| WDR62 | WD repeat domain 62 | 10.4397 |
| NUP188 | nucleoporin 188kDa | 10.2804 |
| WDR1 | WD repeat domain 1 | 10.2804 |
| MIEF2 | mitochondrial elongation factor 2 | 10.0769 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 | 9.83487 |
| ANKRD52 | ankyrin repeat domain 52 | 9.78187 |
| C10ORF76 | chromosome 10 open reading frame 76 | 9.66832 |
| RUSC2 | RUN and SH3 domain containing 2 | 9.44536 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 9.39832 |
| RNMT | RNA (guanine-7-) methyltransferase | 9.30529 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 | 9.17264 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 9.07552 |
| MSN | moesin | 8.9886 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | 8.64382 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 8.45927 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 8.11804 |
| CDHR2 | cadherin-related family member 2 | 8.09326 |
| MEF2A | myocyte enhancer factor 2A | 8.06814 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 8.05521 |
| C1ORF116 | chromosome 1 open reading frame 116 | 7.95231 |
| ANGPTL2 | angiopoietin-like 2 | 7.95231 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 | 7.84222 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | 7.63711 |
| HABP2 | hyaluronan binding protein 2 | 7.6106 |
| TLR4 | toll-like receptor 4 | 7.57089 |
| ALPK2 | alpha-kinase 2 | 7.51056 |
| ZNF41 | zinc finger protein 41 | 7.48317 |
| PDZD3 | PDZ domain containing 3 | 7.41662 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 7.41662 |
| ZFYVE27 | zinc finger, FYVE domain containing 27 | 7.34705 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | 7.29449 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 7.23461 |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 7.22258 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 7.15903 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit | 7.12706 |
| THBS2 | thrombospondin 2 | 7.08442 |
| CRY2 | cryptochrome circadian clock 2 | 6.95112 |
| SPRYD3 | SPRY domain containing 3 | 6.9256 |
| MFN2 | mitofusin 2 | 6.86331 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 6.8458 |
| HDAC6 | histone deacetylase 6 | 6.80538 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | 6.62121 |
| MAP4 | microtubule-associated protein 4 | 6.5969 |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | 6.51364 |
| OTOGL | otogelin-like | 6.50595 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 6.50119 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 6.49609 |
| TOM1 | target of myb1 (chicken) | 6.46253 |
| PPARD | peroxisome proliferator-activated receptor delta | 6.40582 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 6.3897 |
| SH3RF1 | SH3 domain containing ring finger 1 | 6.36269 |
| ATXN2L | ataxin 2-like | 6.25344 |
| RPAP1 | RNA polymerase II associated protein 1 | 6.20791 |
| NLRP1 | NLR family, pyrin domain containing 1 | 6.2059 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 6.17928 |
| TOM1L2 | target of myb1-like 2 (chicken) | 6.10279 |
| SEC24C | SEC24 family member C | 6.08239 |
| HPS4 | Hermansky-Pudlak syndrome 4 | 6.06984 |
| LAMB3 | laminin, beta 3 | 6.02761 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 5.96413 |
| IARS | isoleucyl-tRNA synthetase | 5.95219 |
| RNF123 | ring finger protein 123 | 5.93527 |
| HNF1A | HNF1 homeobox A | 5.87784 |
| SLC25A25 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | 5.87784 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 | 5.86141 |
| ZNF460 | zinc finger protein 460 | 5.76115 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 5.71556 |
| HNF4A | hepatocyte nuclear factor 4, alpha | 5.71556 |
| CDK18 | cyclin-dependent kinase 18 | 5.71108 |
| HKDC1 | hexokinase domain containing 1 | 5.69402 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 5.63754 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) | 5.56792 |
| SRPR | signal recognition particle receptor (docking protein) | 5.53746 |
| BCL2L1 | BCL2-like 1 | 5.53553 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 5.53553 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 5.51311 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) | 5.51009 |
| FAT2 | FAT atypical cadherin 2 | 5.50669 |
| KIAA0922 | KIAA0922 | 5.50255 |
| SCRN1 | secernin 1 | 5.50255 |
| TMEM63B | transmembrane protein 63B | 5.48228 |
| FCHSD1 | FCH and double SH3 domains 1 | 5.44689 |
| SNRK | SNF related kinase | 5.42244 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 | 5.40497 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | 5.40497 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 5.37421 |
| CLTCL1 | clathrin, heavy chain-like 1 | 5.34182 |
| CTC1 | CTS telomere maintenance complex component 1 | 5.30357 |
| NPC1 | Niemann-Pick disease, type C1 | 5.30308 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 5.29459 |
| CNST | consortin, connexin sorting protein | 5.27947 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 5.24465 |
| TFCP2L1 | transcription factor CP2-like 1 | 5.24054 |
| MED12 | mediator complex subunit 12 | 5.22595 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 5.21916 |
| PLD2 | phospholipase D2 | 5.19557 |
| RBM22 | RNA binding motif protein 22 | 5.19521 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MTA2 | metastasis associated 1 family, member 2 | -20.0 |
| TMSB10 | thymosin beta 10 | -20.0 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -18.6576 |
| PTMA | prothymosin, alpha | -16.7486 |
| ROMO1 | reactive oxygen species modulator 1 | -16.1344 |
| ALDOA | aldolase A, fructose-bisphosphate | -14.6953 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -14.1342 |
| NCL | nucleolin | -13.87 |
| TOMM5 | translocase of outer mitochondrial membrane 5 homolog (yeast) | -13.5544 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -13.2468 |
| HIST1H1D | histone cluster 1, H1d | -12.6555 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -12.4772 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -11.064 |
| HSPE1 | heat shock 10kDa protein 1 | -10.7155 |
| C11ORF31 | chromosome 11 open reading frame 31 | -10.4484 |
| MINOS1 | mitochondrial inner membrane organizing system 1 | -10.3733 |
| CETN2 | centrin, EF-hand protein, 2 | -10.2954 |
| ATP5E | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | -10.2804 |
| NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | -10.1818 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -10.0184 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -10.0184 |
| FTH1 | ferritin, heavy polypeptide 1 | -9.67556 |
| ARF6 | ADP-ribosylation factor 6 | -9.66832 |
| HIST2H2AC | histone cluster 2, H2ac | -9.56166 |
| SEC61G | Sec61 gamma subunit | -9.53064 |
| ATP5I | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E | -9.39832 |
| CSTB | cystatin B (stefin B) | -9.29895 |
| RGS10 | regulator of G-protein signaling 10 | -9.28776 |
| SEC61B | Sec61 beta subunit | -9.249 |
| TXN | thioredoxin | -9.249 |
| UQCC3 | ubiquinol-cytochrome c reductase complex assembly factor 3 | -9.16797 |
| RPL35 | ribosomal protein L35 | -9.07552 |
| IFITM2 | interferon induced transmembrane protein 2 | -9.06157 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -8.99146 |
| CSNK2B | casein kinase 2, beta polypeptide | -8.9886 |
| RWDD1 | RWD domain containing 1 | -8.9886 |
| ALDH16A1 | aldehyde dehydrogenase 16 family, member A1 | -8.94625 |
| TFDP1 | transcription factor Dp-1 | -8.74156 |
| CCDC34 | coiled-coil domain containing 34 | -8.71055 |
| HAUS1 | HAUS augmin-like complex, subunit 1 | -8.60213 |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | -8.54208 |
| TMEM14A | transmembrane protein 14A | -8.53793 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -8.51707 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -8.45927 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -8.45927 |
| BST2 | bone marrow stromal cell antigen 2 | -8.42924 |
| ANAPC11 | anaphase promoting complex subunit 11 | -8.42924 |
| PFDN4 | prefoldin subunit 4 | -8.38812 |
| TSPO | translocator protein (18kDa) | -8.32727 |
| MRPL46 | mitochondrial ribosomal protein L46 | -8.32727 |
| CENPU | centromere protein U | -8.32727 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -8.31625 |
| KIAA0101 | KIAA0101 | -8.22492 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | -8.18883 |
| MNS1 | meiosis-specific nuclear structural 1 | -8.17361 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 | -8.11024 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -8.09317 |
| RPL26 | ribosomal protein L26 | -8.09295 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -8.01837 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -8.00633 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -7.9399 |
| RPL32 | ribosomal protein L32 | -7.77084 |
| LINC00493 | long intergenic non-protein coding RNA 493 | -7.69654 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -7.41662 |
| C4ORF3 | chromosome 4 open reading frame 3 | -7.36052 |
| LARP7 | La ribonucleoprotein domain family, member 7 | -7.34133 |
| BOLA3 | bolA family member 3 | -7.33975 |
| C1ORF131 | chromosome 1 open reading frame 131 | -7.32724 |
| SNRNP27 | small nuclear ribonucleoprotein 27kDa (U4/U6.U5) | -7.30995 |
| FTL | ferritin, light polypeptide | -7.30901 |
| IFITM1 | interferon induced transmembrane protein 1 | -7.28617 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | -7.27334 |
| EID1 | EP300 interacting inhibitor of differentiation 1 | -7.27334 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -7.26463 |
| SVIP | small VCP/p97-interacting protein | -7.25545 |
| EIF5B | eukaryotic translation initiation factor 5B | -7.23461 |
| LAGE3 | L antigen family, member 3 | -7.23461 |
| COMMD6 | COMM domain containing 6 | -7.23134 |
| USMG5 | up-regulated during skeletal muscle growth 5 homolog (mouse) | -7.17585 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -7.17585 |
| IFI27L2 | interferon, alpha-inducible protein 27-like 2 | -7.16503 |
| TWIST1 | twist family bHLH transcription factor 1 | -7.15903 |
| ADAM19 | ADAM metallopeptidase domain 19 | -7.15305 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -7.12903 |
| SERF2 | small EDRK-rich factor 2 | -7.10105 |
| PET100 | PET100 homolog (S. cerevisiae) | -7.09672 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -7.05229 |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | -7.05184 |
| HINT1 | histidine triad nucleotide binding protein 1 | -7.04909 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -7.03299 |
| CD99 | CD99 molecule | -7.00266 |
| RANBP1 | RAN binding protein 1 | -6.97283 |
| RPL27 | ribosomal protein L27 | -6.97283 |
| FAM162A | family with sequence similarity 162, member A | -6.97283 |
| TMEM258 | transmembrane protein 258 | -6.96735 |
| MYEOV2 | myeloma overexpressed 2 | -6.94065 |
| XPA | xeroderma pigmentosum, complementation group A | -6.8908 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -6.87877 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -6.86053 |
| SKA2 | spindle and kinetochore associated complex subunit 2 | -6.83687 |
